Pharmacovigilance Manager Jobs
Pharmacovigilance Manager jobs are open across pharmaceutical companies, biotechs, CROs, and medical device firms, with specializations in drug safety reporting, risk management, and regulatory affairs, at levels from associate manager to senior director. Find a role that fits below and apply directly.
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Open roles9
Top stateMassachusetts
Top employerAmgen
Top cityWaltham, MA
Work type40% Remote
Top industryBiotechnology
Showing 5 of 9+ Pharmacovigilance Manager jobs
Senior Manager, Pharmacovigilance Scientist
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Added 3w ago
Immunocore
Senior Manager, Pharmacovigilance Scientist
Gaithersburg, Maryland
Added 3w ago
Senior Manager, Pharmacovigilance Operations
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Added 3w ago
Viridian Therapeutics
Senior Manager, Pharmacovigilance Operations
Waltham, Massachusetts
Added 3w ago
Senior Manager, Clinical Trial Delivery and Pharmacovigilance Documentation Excellence
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Added 1mo ago
Takeda Pharmaceuticals
Senior Manager, Clinical Trial Delivery and Pharmacovigilance Documentation Excellence
Cambridge, Massachusetts
Added 1mo ago
Senior Manager, Drug Safety & Pharmacovigilance
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Added 1mo ago
Travere Therapeutics
Senior Manager, Drug Safety & Pharmacovigilance
San Diego, California
Added 1mo ago
Project Manager - Pharmacovigilance
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Added 1mo ago
United Biosource Corporation
Project Manager - Pharmacovigilance
Remote
Added 1mo ago
Added 3w ago
Senior Manager, Pharmacovigilance Scientist
Immunocore·Gaithersburg, Maryland
Job functions:
$145k - $170k/yr
Master's degree in nursing
Job Description
Vacancy No
VN898
Employment Type
Full Time
Location of role
Gaithersburg, MD, Radnor, PA, Oxford, UK
Department
Regulatory Affairs
Key Responsibilities
The Senior Manager, Pharmacovigilance Scientist applies broad expertise in pharmacovigilance and related activities for assigned development and marketed products throughout the product lifecycle.
The role is responsible for leading product-level safety surveillance, signal management, benefit-risk evaluation, aggregate safety reporting, and risk management planning while ensuring compliance with global pharmacovigilance regulations and company procedures. The Senior Manager addresses safety problems that require evaluating variables and integrating data from multiple clinical, nonclinical, and post-marketing areas. The individual determines the methodology used for safety analyses, exercises independent judgment in developing methods and evaluation criteria, and serves as a best-practice resource within Global Patient Safety.
Working collaboratively with Safety Physicians and Pharmacovigilance Operations, the Senior Manager contributes directly to the development of pharmacovigilance strategy within their area, drives the safety strategy of larger cross-functional projects, and represents the function in interactions with cross-functional project teams, safety governance committees, and executive-level colleagues. The individual may lead functional project teams and may directly oversee external vendors in the Safety Sciences area.
KEY RESPONSIBILITIES
Lead safety surveillance for assigned investigational and/or marketed products.
Lead signal detection, evaluation, documentation, communication, and closure in accordance with Immunocore procedures and global regulatory requirements.
Integrate and interpret safety data from clinical trials, individual case safety reports, literature, aggregate analyses, and other relevant sources.
Lead benefit-risk assessments and communicate recommendations to Safety Management Teams and governance bodies.
Escalate emerging safety issues and potential risks to appropriate senior stakeholders.
Lead the planning, authoring, review, and timely delivery of aggregate safety reports, including DSURs, PBRERs/PSURs, and PADERs, as applicable.
Lead or review key safety documents, including Investigator Brochures, Reference Safety Information, Risk Management Plans, and safety sections of regulatory submissions.
Ensure safety documentation is scientifically rigorous, consistent, and compliant with global regulatory requirements.
Establish and manage timelines, cross-functional review processes, and quality standards for assigned deliverables
Lead development and maintenance of product-specific pharmacovigilance plans and Risk Management Plans.
Evaluate risk-minimization measures and post-authorization safety commitments.
Provide pharmacovigilance input to clinical development, protocol design, safety monitoring, labeling, and lifecycle-management activities.
Partner with Regulatory Affairs and Medical Affairs to ensure consistent safety messaging.
Represent Pharmacovigilance on program teams, governance forums, and relevant internal and external meetings.
Coordinate work performed by assigned cross-functional contributors, contractors, consultants, or vendors.
Maintain compliance with applicable global pharmacovigilance regulations, Immunocore procedures, and inspection-readiness requirements.
Support Health Authority questions, audits, inspections, deviation investigations, and CAPA activities.
Serve as a best-practice resource and lead process improvements, including development or revision of SOPs and work instructions.
Maintain current knowledge of pharmacovigilance regulations, industry guidance, and relevant therapeutic-area science.
SUPERVISORY RESPONSIBILITY
This position does not have direct line management responsibilities.
COMPETENCIES
Strong understanding of pharmacovigilance principles, benefit-risk assessment, and global drug safety regulations.
Scientific and analytical thinking with the ability to interpret complex safety data.
Experience performing signal detection and aggregate safety analyses.
Excellent written communication and scientific writing skills.
Strong organizational and project management abilities.
Ability to work independently while collaborating effectively across multidisciplinary teams.
Sound judgment, attention to detail, and commitment to patient safety and regulatory compliance.
Proficiency with safety databases and pharmacovigilance systems.
EXPERIENCE & KNOWLEDGE
Essential
12+ years of experience within the biotechnology or pharmaceutical industry.
Experience supporting safety surveillance for clinical development and/or marketed products.
Experience with signal detection, signal evaluation, and benefit-risk assessment.
Experience authoring or contributing to aggregate safety reports (DSURs, PBRERs/PSURs, PADERs, RMP).
Working knowledge of global pharmacovigilance regulations including FDA, EMA, MHRA, ICH, GVP, and CIOMS.
Proven track record of presenting complex scientific and safety information to governance bodies and senior/executive-level colleagues.
Experience participating in or supporting regulatory inspections, audits, and CAPA remediation.
Demonstrated capacity to lead cross-functional project teams and mentor junior professional colleagues.
Desirable
Experience with biologics, oncology, immunology, TCR therapeutics, or other advanced therapies.
Experience with post-marketing safety commitments, PASS studies, or risk-minimization effectiveness assessments.
Experience working with safety databases such as Argus, ARISg, or Veeva Safety.
Working familiarity with pharmacoepidemiology, observational studies, or real-world data.
Relevant professional certification in pharmacovigilance or drug safety.
EDUCATION & QUALIFICATIONS
Bachelor’s degree in life sciences, pharmacy, nursing, or a related scientific discipline.
Advanced degree in life sciences, pharmacy, nursing, public health, or related scientific discipline (MS, PharmD, PhD preferred).
Relevant pharmacovigilance or drug safety certification is desirable.
Excellent written and verbal English communication skills.
US Salary Range
$145,000 to $170,000
The role is responsible for leading product-level safety surveillance, signal management, benefit-risk evaluation, aggregate safety reporting, and risk management planning while ensuring compliance with global pharmacovigilance regulations and company procedures. The Senior Manager addresses safety problems that require evaluating variables and integrating data from multiple clinical, nonclinical, and post-marketing areas. The individual determines the methodology used for safety analyses, exercises independent judgment in developing methods and evaluation criteria, and serves as a best-practice resource within Global Patient Safety.
Working collaboratively with Safety Physicians and Pharmacovigilance Operations, the Senior Manager contributes directly to the development of pharmacovigilance strategy within their area, drives the safety strategy of larger cross-functional projects, and represents the function in interactions with cross-functional project teams, safety governance committees, and executive-level colleagues. The individual may lead functional project teams and may directly oversee external vendors in the Safety Sciences area.
KEY RESPONSIBILITIES
SUPERVISORY RESPONSIBILITY
This position does not have direct line management responsibilities.
COMPETENCIES
EXPERIENCE & KNOWLEDGE
Essential
Desirable
EDUCATION & QUALIFICATIONS
US Salary Range
$145,000 to $170,000
About the Company
Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
Immunocore
Senior Manager, Pharmacovigilance Scientist
Gaithersburg, Maryland
Added 3w ago
Job functions:
$145k - $170k/yr
Master's degree in nursing
Job Description
Vacancy No
VN898
Employment Type
Full Time
Location of role
Gaithersburg, MD, Radnor, PA, Oxford, UK
Department
Regulatory Affairs
Key Responsibilities
The Senior Manager, Pharmacovigilance Scientist applies broad expertise in pharmacovigilance and related activities for assigned development and marketed products throughout the product lifecycle.
The role is responsible for leading product-level safety surveillance, signal management, benefit-risk evaluation, aggregate safety reporting, and risk management planning while ensuring compliance with global pharmacovigilance regulations and company procedures. The Senior Manager addresses safety problems that require evaluating variables and integrating data from multiple clinical, nonclinical, and post-marketing areas. The individual determines the methodology used for safety analyses, exercises independent judgment in developing methods and evaluation criteria, and serves as a best-practice resource within Global Patient Safety.
Working collaboratively with Safety Physicians and Pharmacovigilance Operations, the Senior Manager contributes directly to the development of pharmacovigilance strategy within their area, drives the safety strategy of larger cross-functional projects, and represents the function in interactions with cross-functional project teams, safety governance committees, and executive-level colleagues. The individual may lead functional project teams and may directly oversee external vendors in the Safety Sciences area.
KEY RESPONSIBILITIES
Lead safety surveillance for assigned investigational and/or marketed products.
Lead signal detection, evaluation, documentation, communication, and closure in accordance with Immunocore procedures and global regulatory requirements.
Integrate and interpret safety data from clinical trials, individual case safety reports, literature, aggregate analyses, and other relevant sources.
Lead benefit-risk assessments and communicate recommendations to Safety Management Teams and governance bodies.
Escalate emerging safety issues and potential risks to appropriate senior stakeholders.
Lead the planning, authoring, review, and timely delivery of aggregate safety reports, including DSURs, PBRERs/PSURs, and PADERs, as applicable.
Lead or review key safety documents, including Investigator Brochures, Reference Safety Information, Risk Management Plans, and safety sections of regulatory submissions.
Ensure safety documentation is scientifically rigorous, consistent, and compliant with global regulatory requirements.
Establish and manage timelines, cross-functional review processes, and quality standards for assigned deliverables
Lead development and maintenance of product-specific pharmacovigilance plans and Risk Management Plans.
Evaluate risk-minimization measures and post-authorization safety commitments.
Provide pharmacovigilance input to clinical development, protocol design, safety monitoring, labeling, and lifecycle-management activities.
Partner with Regulatory Affairs and Medical Affairs to ensure consistent safety messaging.
Represent Pharmacovigilance on program teams, governance forums, and relevant internal and external meetings.
Coordinate work performed by assigned cross-functional contributors, contractors, consultants, or vendors.
Maintain compliance with applicable global pharmacovigilance regulations, Immunocore procedures, and inspection-readiness requirements.
Support Health Authority questions, audits, inspections, deviation investigations, and CAPA activities.
Serve as a best-practice resource and lead process improvements, including development or revision of SOPs and work instructions.
Maintain current knowledge of pharmacovigilance regulations, industry guidance, and relevant therapeutic-area science.
SUPERVISORY RESPONSIBILITY
This position does not have direct line management responsibilities.
COMPETENCIES
Strong understanding of pharmacovigilance principles, benefit-risk assessment, and global drug safety regulations.
Scientific and analytical thinking with the ability to interpret complex safety data.
Experience performing signal detection and aggregate safety analyses.
Excellent written communication and scientific writing skills.
Strong organizational and project management abilities.
Ability to work independently while collaborating effectively across multidisciplinary teams.
Sound judgment, attention to detail, and commitment to patient safety and regulatory compliance.
Proficiency with safety databases and pharmacovigilance systems.
EXPERIENCE & KNOWLEDGE
Essential
12+ years of experience within the biotechnology or pharmaceutical industry.
Experience supporting safety surveillance for clinical development and/or marketed products.
Experience with signal detection, signal evaluation, and benefit-risk assessment.
Experience authoring or contributing to aggregate safety reports (DSURs, PBRERs/PSURs, PADERs, RMP).
Working knowledge of global pharmacovigilance regulations including FDA, EMA, MHRA, ICH, GVP, and CIOMS.
Proven track record of presenting complex scientific and safety information to governance bodies and senior/executive-level colleagues.
Experience participating in or supporting regulatory inspections, audits, and CAPA remediation.
Demonstrated capacity to lead cross-functional project teams and mentor junior professional colleagues.
Desirable
Experience with biologics, oncology, immunology, TCR therapeutics, or other advanced therapies.
Experience with post-marketing safety commitments, PASS studies, or risk-minimization effectiveness assessments.
Experience working with safety databases such as Argus, ARISg, or Veeva Safety.
Working familiarity with pharmacoepidemiology, observational studies, or real-world data.
Relevant professional certification in pharmacovigilance or drug safety.
EDUCATION & QUALIFICATIONS
Bachelor’s degree in life sciences, pharmacy, nursing, or a related scientific discipline.
Advanced degree in life sciences, pharmacy, nursing, public health, or related scientific discipline (MS, PharmD, PhD preferred).
Relevant pharmacovigilance or drug safety certification is desirable.
Excellent written and verbal English communication skills.
US Salary Range
$145,000 to $170,000
The role is responsible for leading product-level safety surveillance, signal management, benefit-risk evaluation, aggregate safety reporting, and risk management planning while ensuring compliance with global pharmacovigilance regulations and company procedures. The Senior Manager addresses safety problems that require evaluating variables and integrating data from multiple clinical, nonclinical, and post-marketing areas. The individual determines the methodology used for safety analyses, exercises independent judgment in developing methods and evaluation criteria, and serves as a best-practice resource within Global Patient Safety.
Working collaboratively with Safety Physicians and Pharmacovigilance Operations, the Senior Manager contributes directly to the development of pharmacovigilance strategy within their area, drives the safety strategy of larger cross-functional projects, and represents the function in interactions with cross-functional project teams, safety governance committees, and executive-level colleagues. The individual may lead functional project teams and may directly oversee external vendors in the Safety Sciences area.
KEY RESPONSIBILITIES
SUPERVISORY RESPONSIBILITY
This position does not have direct line management responsibilities.
COMPETENCIES
EXPERIENCE & KNOWLEDGE
Essential
Desirable
EDUCATION & QUALIFICATIONS
US Salary Range
$145,000 to $170,000
About the Company
Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
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Find JobsPharmacovigilance Manager Job Market
Who's Hiring
Top Industries Hiring
- Biotechnology & Pharmaceuticals
What Employers Look For
The qualifications that appear most often in pharmacovigilance manager jobs.
- Bachelor's or advanced degree in life sciences, pharmacy, medicine, or a related field
- Direct experience with individual case safety report processing and aggregate safety reporting
- Proficiency with an adverse event management system such as Argus or ARISg
- Familiarity with ICH E2 guidelines and applicable FDA or EMA pharmacovigilance regulations
- Experience authoring or reviewing PSURs, PBRERs, or RMPs for regulatory submission
- Strong signal detection, risk assessment, and cross-functional collaboration skills
Tips for Your Pharmacovigilance Manager Job Search
Tailor your resume to signal reporting depth
Hiring managers scan for concrete signal processing experience, so call out the specific databases you've worked in, the adverse event volumes you've managed, and any periodic safety update reports you've authored. Vague descriptions of 'safety monitoring' get passed over fast.
Highlight your regulatory submission experience clearly
Many pharmacovigilance manager postings require hands-on experience with IND, NDA, or BLA submissions. If you've contributed to a PSUR, PBRER, or REMS document, name the submission type explicitly rather than burying it under general 'regulatory support' language.
Apply early to roles that fit
Migrate Mate lists pharmacovigilance manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Target postings by therapeutic area alignment
Oncology, rare disease, and cardiovascular drug programs each carry distinct safety reporting demands. When you apply to a posting in a specific therapeutic area, reference any prior experience in that area explicitly so reviewers don't have to infer the connection.
Prepare a case narrative for every interview round
Interviewers frequently ask you to walk through a real signal detection or aggregate report scenario end to end. Having one strong case narrative ready, covering your data source, methodology, regulatory decision, and outcome, keeps your answers concrete and interview-ready.
Negotiate start date around any notice period obligations
Drug safety teams often need pharmacovigilance managers to begin during an active regulatory cycle, so a compressed start timeline is common. Knowing your exact notice obligation in advance lets you counter a rushed start date without losing the offer.
Pharmacovigilance Manager Jobs: Frequently Asked Questions
Which companies are hiring the most pharmacovigilance managers?
Amgen, Insmed, and Immunocore are hiring the most pharmacovigilance managers right now, with openings concentrated in Massachusetts, California, and Virginia, based on current listings on Migrate Mate as of November 2026. Demand tends to cluster around companies with active late-stage pipelines or post-market safety commitments.
How many pharmacovigilance manager jobs are remote?
About 80% of pharmacovigilance manager openings are fully remote or hybrid as of November 2026, reflecting the document-heavy, system-based nature of much of the work. Roles focused on aggregate reporting, case processing oversight, and signal management are the most likely to offer remote or hybrid arrangements, while positions requiring close site coordination may remain on-site.
How do you become a pharmacovigilance manager?
Most pharmacovigilance managers start in an individual case safety reporting or drug safety associate role, build experience with adverse event databases and regulatory submissions, then move into a senior associate or specialist position before stepping into management. Earning familiarity with ICH E2 guidelines, completing relevant continuing education, and taking on cross-functional project ownership accelerates the path to a manager title.
Can you get a pharmacovigilance manager job without direct management experience?
Yes, many employers will consider candidates who have led safety reporting projects, mentored junior staff, or coordinated cross-functional review meetings, even without a formal direct-report title. Framing those experiences in terms of accountability, decision-making, and team outcomes helps close the gap. Some smaller biotechs and CROs explicitly hire strong individual contributors into their first pharmacovigilance manager role.
What does the pharmacovigilance manager interview process look like?
The process typically starts with a recruiter screen, followed by a hiring manager interview focused on your regulatory and reporting experience. A technical panel or case study round often comes next, where you walk through a signal detection or aggregate report scenario. Final rounds usually involve senior directors or cross-functional partners in medical affairs or regulatory, and some employers include a short written exercise.
Where can I find and apply to pharmacovigilance manager jobs?
You can find and apply to pharmacovigilance manager jobs on Migrate Mate, which lists current openings from pharmaceutical companies, biotechs, CROs, and medical device firms across the United States. Find roles that match your experience and apply directly to each listing.
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