Physician Assistant Jobs in Columbia, SC
Physician assistant jobs in Columbia, South Carolina are concentrated in the Midlands medical corridor, the Vista district, and Forest Acres, with strong demand across hospital systems, urgent care networks, and specialty clinics. Employers hiring right now include Prisma Health, Lexington Health, and Prisma Health Urgent Care. Find a role that fits below and apply directly.
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Job Summary
Provides assistant surgical services in the operating room as well as other selected medical services under the direction of the surgeon.- Provides general surgical assistant services in operating room.10%
- Assists surgeon with prepping and until completion of procedure.15%
- Removes drains, tubes and catheters.10%
- Closes incisions.15%
- Assists with patient office visits and assumes call when assigned. 10%
- Performs all charting, summaries, correspondence and required paperwork for purposes of documenting care and billing. 10%
- Participates in physician educational programs provided by Employer relative to capitated medicine and implications relative to physician practice patterns. 5%
- Participates in:
Establishment of quality assurance programs
Establishment of Utilization Management programs
Selection of management information systems
Development of patient education surveys
Development of patient satisfaction surveys 5%- Assists in the development of operational and capital budgets. 5%
- Participates in operational assessments in search of revenue enhancement, expense reductions, consolidation efficiencies and billing opportunities. 5%
- Assists in post-operative care of patients including daily rounds and wound assessments. 10%
Physician Assistant Program or Program Certificate equivalent
1 year - Appropriate Clinical Experience
- NCCPA certification and current Physician Assistant licensure in the state in which the team member is working.
- BLS
- Prescriptive Authority for state in which team member is working
- Controlled Substance license for state in which team member is working; Federal DEA license
Completion of Physician Assistant Surgical Residency Program or approved Surgical Physician Assistant graduate program
Work Shift
Day (United States of America)Location
1333 Taylor St BaptistFacility
3488 Surgical 1333 Taylor 5FDepartment
34881000 Surgical 1333 Taylor 5F-Practice OperationsShare your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.
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Find Physician Assistant JobsPhysician Assistant Job Market in Columbia
Who's Hiring
- Prisma Health21

- Lexington Health6

- Prisma Health Urgent Care4

- Optum1

- Curana Health1

Top Industries Hiring
- Healthcare & Medical Services26
- Consulting & Professional Services8
- Agriculture & Farming1
Physician Assistant Jobs in Columbia: Frequently Asked Questions
How do I get a physician assistant job in Columbia?
The strongest path into Columbia's PA market is through its large hospital systems and the network of specialty and urgent care clinics that surround them in areas like Forest Acres, Northeast Columbia, and the Midlands corridor. Candidates with surgical, emergency medicine, or primary care rotations stand out. Applying directly to health system career portals and targeting multisite clinic groups gives you the best local traction.
Which companies hire physician assistants in Columbia?
Employers hiring physician assistants in Columbia right now include Prisma Health, Lexington Health, and Prisma Health Urgent Care, based on current listings on Migrate Mate as of July 2026. Columbia's market is anchored by academic medical centers, large regional health systems, and a growing layer of independent specialty and urgent care practices throughout the metro.
Are there remote physician assistant jobs in Columbia?
Yes, though remote opportunities are limited for physician assistants given the hands-on, patient-facing nature of most roles. About 0% of physician assistant openings tied to Columbia are remote or hybrid as of July 2026, and those roles tend to be in telemedicine triage, utilization review, or care management functions connected to Columbia's larger health system employers.
How can I get a physician assistant job in Columbia with little or no experience?
The most realistic entry path in Columbia is through large health system residency or post-graduate training programs, which give new graduates supervised clinical hours in a structured setting. Multisite urgent care groups and federally qualified health centers in the Midlands region also hire new graduates into supervised roles. Demonstrating strong rotation performance and local clinical connections accelerates hiring in a market where most openings are filled through internal referrals.
Which industries hire the most physician assistants in Columbia?
The sectors hiring the most physician assistants in Columbia are Healthcare & Medical Services, Consulting & Professional Services, and Agriculture & Farming, based on current listings on Migrate Mate as of July 2026. Columbia's role as a state capital and home to a major research university health system drives consistent demand across those sectors, reinforced by the region's expanding network of outpatient specialty and primary care facilities.
Related Jobs in South Carolina
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