Platform Engineer Jobs in South Carolina
Platform Engineer jobs in South Carolina are drawing steady demand across financial services, defense contracting, and healthcare technology, with openings at every level from junior engineer to principal architect. Most hiring is concentrated in Charlotte-adjacent markets like Fort Mill and Rock Hill, along with Columbia and Charleston, where employers such as Blackbaud, Booz Allen Hamilton, and SCANA-affiliated utilities maintain engineering teams. Cloud infrastructure automation, Kubernetes orchestration, and CI/CD pipeline development are the specialties appearing most consistently in South Carolina postings. Scan the live roles below and apply to whichever ones fit.
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Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
We are seeking a Senior Staff Software Engineer to help architect and build the data platform and backend services for our healthcare SaaS solutions. This is a hands-on technical leadership role requiring deep expertise in database and data architecture, cloud-native backend development, scalability, security, and healthcare interoperability.
The ideal candidate combines strong software engineering skills with the ability to design secure, high-performance data architectures for large-scale, multi-tenant applications handling sensitive healthcare data.
Key Responsibilities
- Architect and develop scalable backend services and data platforms for multi-tenant SaaS applications.
- Design and optimize relational and non-relational database architectures, data models, and storage strategies.
- Build scalable data ingestion, integration, and processing capabilities for large and complex healthcare datasets.
- Design cloud-native data architectures incorporating databases, data lakes/lakehouses, and distributed data platforms.
- Develop APIs and integration capabilities supporting healthcare interoperability, including HL7 and FHIR.
- Ensure appropriate architecture for security, encryption, access control, auditability, data governance, retention, and regulatory compliance.
- Design for high availability, disaster recovery, performance, and scalability.
- Provide technical leadership and architectural guidance while remaining hands-on with design and development.
- Collaborate with Software Engineering, Product, Security, Quality, and Regulatory teams.
Required Qualifications
- Bachelor’s or Master’s degree in Computer Science, Engineering, Information Systems, or related field.
- 10+ years of software engineering experience, including significant backend and data-platform development.
- Deep experience designing and optimizing relational databases such as PostgreSQL, SQL Server, or MySQL.
- Experience with NoSQL technologies such as MongoDB, Cosmos DB, or equivalent.
- Strong experience with cloud platforms (Azure, AWS, or GCP) and cloud-native architectures.
- Experience with modern data pipelines, ingestion frameworks, data lakes/lakehouses, and distributed data architectures.
- Strong understanding of multi-tenant SaaS architecture, APIs, scalability, security, and data governance.
- Experience designing systems that handle sensitive or regulated data.
Preferred Qualifications
- Healthcare software or regulated-industry experience.
- Experience with HL7, FHIR, EHR/EMR integration, or healthcare interoperability.
- Experience with Databricks, Azure Data Factory, Kafka, Spark, or similar technologies.
- Experience with containerized environments such as Docker and Kubernetes.
Compensation and Benefits
The salary range estimated for this position based in Indiana is $135,800.00–$203,750.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
We are seeking a Senior Staff Software Engineer to help architect and build the data platform and backend services for our healthcare SaaS solutions. This is a hands-on technical leadership role requiring deep expertise in database and data architecture, cloud-native backend development, scalability, security, and healthcare interoperability.
The ideal candidate combines strong software engineering skills with the ability to design secure, high-performance data architectures for large-scale, multi-tenant applications handling sensitive healthcare data.
Key Responsibilities
- Architect and develop scalable backend services and data platforms for multi-tenant SaaS applications.
- Design and optimize relational and non-relational database architectures, data models, and storage strategies.
- Build scalable data ingestion, integration, and processing capabilities for large and complex healthcare datasets.
- Design cloud-native data architectures incorporating databases, data lakes/lakehouses, and distributed data platforms.
- Develop APIs and integration capabilities supporting healthcare interoperability, including HL7 and FHIR.
- Ensure appropriate architecture for security, encryption, access control, auditability, data governance, retention, and regulatory compliance.
- Design for high availability, disaster recovery, performance, and scalability.
- Provide technical leadership and architectural guidance while remaining hands-on with design and development.
- Collaborate with Software Engineering, Product, Security, Quality, and Regulatory teams.
Required Qualifications
- Bachelor’s or Master’s degree in Computer Science, Engineering, Information Systems, or related field.
- 10+ years of software engineering experience, including significant backend and data-platform development.
- Deep experience designing and optimizing relational databases such as PostgreSQL, SQL Server, or MySQL.
- Experience with NoSQL technologies such as MongoDB, Cosmos DB, or equivalent.
- Strong experience with cloud platforms (Azure, AWS, or GCP) and cloud-native architectures.
- Experience with modern data pipelines, ingestion frameworks, data lakes/lakehouses, and distributed data architectures.
- Strong understanding of multi-tenant SaaS architecture, APIs, scalability, security, and data governance.
- Experience designing systems that handle sensitive or regulated data.
Preferred Qualifications
- Healthcare software or regulated-industry experience.
- Experience with HL7, FHIR, EHR/EMR integration, or healthcare interoperability.
- Experience with Databricks, Azure Data Factory, Kafka, Spark, or similar technologies.
- Experience with containerized environments such as Docker and Kubernetes.
Compensation and Benefits
The salary range estimated for this position based in Indiana is $135,800.00–$203,750.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
See All 7 Platform Engineer Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Platform Engineer JobsPlatform Engineer Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Platform Engineer Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
What South Carolina Employers Look For
The qualifications that appear most often in platform engineer jobs across South Carolina.
- Bachelor's degree in computer science, software engineering, or a related technical field
- Hands-on experience with Kubernetes, Docker, and container orchestration at scale
- Proficiency with infrastructure-as-code tools such as Terraform or Ansible
- Experience designing and maintaining CI/CD pipelines using Jenkins, GitLab, or similar tooling
- Familiarity with major cloud platforms including AWS, Azure, or Google Cloud
- Strong scripting ability in Python, Bash, or Go for automation and tooling development
Platform Engineer Jobs in South Carolina: Frequently Asked Questions
How do you become a platform engineer in South Carolina?
Platform engineering has no state-issued license in South Carolina, so entry is credential-and-experience driven. Most employers expect a bachelor's degree in computer science or a closely related field, though some hire from associate programs at technical colleges like Trident Technical or Midlands Technical. Cloud certifications from AWS or Google, combined with a portfolio of infrastructure projects on version-controlled repositories, are the clearest edge for candidates entering the South Carolina market.
Which companies hire platform engineers in South Carolina?
South Carolina platform engineer roles are posted by LPL Financial, Akima, and CVS Health and others right now, based on current listings on Migrate Mate as of November 2026. Defense contractors around the Joint Base Charleston corridor and financial technology firms headquartered in the Charlotte metro's South Carolina suburbs are particularly consistent sources of platform engineer openings.
Which South Carolina cities have the most platform engineer jobs?
Fort Mill, South Carolina, and Mauldin account for the largest share of platform engineer openings in South Carolina. Columbia's concentration of state government agencies, university systems, and regional financial institutions drives demand there, while Charleston's defense and aerospace presence and the Fort Mill and Rock Hill corridor's proximity to Charlotte's financial technology sector explain activity in those markets.
Are there remote platform engineer jobs in South Carolina?
Yes, and more than most fields. About 100% of platform engineer openings tied to South Carolina are remote or hybrid as of November 2026, reflecting how much of the work lives in cloud consoles and code repositories rather than physical infrastructure. The most fully remote roles tend to be in cloud-native tooling, internal developer platform development, and automation engineering, where output is measured by deployed code rather than on-site presence.
How can I get hired as a platform engineer in South Carolina with little or no experience?
The most realistic entry path is a DevOps or site reliability associate role, which several South Carolina employers use as a feeder into full platform engineering positions. Booz Allen Hamilton and defense contractors in the Charleston area run structured associate programs for recent graduates of computer science or information technology programs. Candidates who can demonstrate working Terraform configurations, a GitHub portfolio, and a cloud practitioner certification from AWS have a concrete edge when approaching South Carolina employers with no prior full-time platform experience.
Where can I find and apply to platform engineer jobs in South Carolina?
You can find and apply to platform engineer jobs in South Carolina on Migrate Mate, which lists current openings in the state. Search the available roles, identify the ones that match your experience and location preference, and apply directly to whichever positions fit.
See All 7 Platform Engineer Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Platform Engineer Jobs