Principal Medical Science Liaison Jobs
Principal Medical Science Liaison jobs are open across pharmaceutical, biotechnology, and medical device companies, from senior MSL to principal and director level, with specializations in oncology, rare disease, and immunology. Scan the live roles below and apply to whichever ones fit.
Find JobsLooking for remote work? View remote principal medical science liaison jobs →Overview
Showing 5 of 438+ Principal Medical Science Liaison jobs











Salt Lake City, United States of America | Full time | Field-based | R1569875
Join a Team Advancing Innovation in Hematologic Malignancies - Hematology/Oncology Medical Science Liaison
IQVIA is seeking experienced Medical Science Liaisons (MSLs) to support a late-stage clinical development program in Acute Myeloid Leukemia (AML). This role provides the opportunity to engage with investigators, hematologists, oncologists, and other healthcare professionals at the forefront of AML research and patient care.
The MSL serves as a field-based scientific resource responsible for facilitating scientific exchange, communicating clinical and translational data, and gathering insights related to disease biology, treatment approaches, measurable residual disease (MRD), relapse risk, and evolving standards of care. The role is intended to strengthen the organization's understanding of the scientific and clinical landscape while supporting Medical Affairs and clinical development objectives through meaningful engagement with the oncology community.
Minimum Requirements:
- Advanced clinical or scientific degree required; PharmD, MD, DO, PhD, DNP, NP, PA or equivalent strongly preferred from an accredited institution.
- Minimum of 4 years of Medical Science Liaison (MSL) experience or relevant clinical experience (including being a clinical development scientist in pharma/ biotech) within hematology and/or oncology.
- Minimum 3 years of experience in hematology/oncology required, with demonstrated therapeutic area expertise.
- Demonstrated track record of success in medical affairs, clinical development, clinical practice, scientific engagement, or related healthcare roles.
- Strong understanding of healthcare stakeholder segments, treatment landscapes, and market dynamics within oncology.
- Proven ability to communicate complex scientific and clinical information effectively to diverse audiences, including healthcare professionals, researchers, and key opinion leaders.
- Proficiency with business and communication technologies, including CRM platforms, Microsoft Office Suite, Microsoft Teams, and other digital engagement tools.
- Ability to work independently while collaborating effectively within cross-functional teams.
- Position may require compliance with client-specific site access requirements, including applicable vaccination or health screening protocols.
- Familiarity with the planning and execution of clinical trials in oncology and the processes underlying independent investigator-initiated clinical and/or translational research studies, including registries and observational studies.
- Knowledge of treatment guidelines, clinical research processes, FDA regulations and OIG guidelines.
- Valid driver's license and ability to travel extensively within the assigned territory.
- Willingness and ability to travel up to 70% of the time.
Preferred Experience:
- Experience supporting AML, MDS, bone marrow transplant, cellular therapy, cancer immunotherapy, or related hematologic malignancies.
- Prior product launch experience within the oncology or rare disease ‘space’.
- Existing strong relationships with academic and community hematology/oncology centers.
Networking and partnering with important external customers, including medical thought leaders, academic institutions, NCI Cooperative groups (e.g., ECOG-ACRIN, SWOG, etc.), various clinical trial consortia, large group community practices, medical directors of clinical groups, CMS and insurance carriers, as well as oncology pharmacy directors.
Position Descriptions and Duties:
Scientific Exchange & Stakeholder Engagement
- Develop and maintain scientific relationships with KOLs, academic investigators, community hematology/oncology leaders, and priority institutions across the assigned territory.
- Engage in compliant, peer-to-peer scientific discussions regarding AML, hematologic malignancies, immunotherapy approaches, mechanisms of action, clinical trial data, biomarkers, MRD, relapse risk, and evolving standards of care.
- Communicate complex clinical and scientific information clearly and credibly to diverse external stakeholders, including physicians, researchers, advanced practice providers, pharmacists, nurses, and multidisciplinary care teams.
- Support disease-state education, scientific education programs, advisory boards, investigator meetings, and other medical activities, as appropriate and in accordance with approved materials and compliance requirements.
- Tactically execute scientific exchange with healthcare professionals (HCPs), KOLs, formulary committees, and other key stakeholders using client company-approved material.
- Identify medical community training and educational needs.
- Serve as a first and direct point of contact for investigators for the initiation of investigator-initiated studies.
- Provide investigators with technical support for study development.
- Identify and communicate key clinical and research issues from industry leaders to MSL leadership to help shape company research, development, marketing plans and strategies.
- Maintain clinical expertise through aggressive self-education, including attendance at relevant conferences, scientific workshops and review of key journals.
- Increase client company visibility with current and future thought leaders.
- Enhance professional interaction between client company and industry leaders.
Insight Generation & Strategic Medical Intelligence
- Capture and communicate actionable field insights related to unmet medical needs, clinical practice patterns, treatment barriers, evidence gaps, stakeholder perceptions, patient identification, sequencing considerations, and adoption considerations.
- Synthesize external insights into clear, objective themes and strategic recommendations that inform Medical Affairs, Clinical Development, evidence generation, scientific communications, and launch readiness activities.
- Monitor and communicate developments in the competitive landscape, emerging data, clinical trial activity, guideline evolution, congress intelligence, and investigator interests within AML and related hematologic malignancies.
- Serve as the voice of external oncology stakeholders internally, ensuring field-derived perspectives are integrated into strategic planning and cross-functional decision-making.
Clinical Development & Research Support
- Identify and cultivate relationships with current and potential clinical trial investigators, research centers, cooperative groups, and institutions with expertise in AML, MDS, transplant, cellular therapy, and related hematologic malignancies.
- Identify, establish and maintain collaborative relationships with key investigators/ key opinion leaders and institutions strategic to the effective use of company products at a tactical level.
- Support scientific discussions related to ongoing and planned clinical development programs, including trial awareness and site engagement activities, as appropriate.
- Maintain current knowledge of relevant clinical literature, congress data, trial designs, endpoints, and emerging therapeutic approaches in hematologic oncology.
- Identify clinical research opportunities that are consistent with company objectives.
Medical Affairs Collaboration & Execution
- Partner with Medical Affairs leadership and cross-functional colleagues to execute the field medical plan
- Document scientific interactions and insights accurately and timely in the appropriate CRM or insight management system.
- Maintain the highest standards of scientific integrity, ethics, and compliance in all external and internal activities.
#LI-CES
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com
IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe
IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
The potential base pay range for this role is $170,000-$210,000 annually. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.Where you'll work
Field-based
You’ll work where the action is — out in the field, directly engaging with our customers, sites or partners. Field-based roles offer the opportunity to build relationships face-to-face, gain real-world insights and make a tangible impact.
Culture
Culture at IQVIA is built on a shared belief: that when people are empowered with better data, smarter technology and deeper expertise, they can change what’s possible for patients. Across every team and every corner of the globe, you’ll find colleagues who genuinely care — about the mission and about each other. That’s what makes this a place where people tend to stay, grow and do the best work of their careers.
Principal Medical Science Liaison Jobs by Experience Level
See All 438+ Principal Medical Science Liaison Jobs
Find roles that match your experience and apply in just a few clicks.
Find JobsPrincipal Medical Science Liaison Job Market
Who's Hiring
- Amgen70

- Syneos Health Commercial Solutions38

- サイネオス・ヘルス37

- IQVIA24

- Praxis Precision Medicines16

Top Industries Hiring
- Biotechnology & Pharmaceuticals37
- Healthcare & Medical Services10
- Science & Research9
- Consulting & Professional Services7
- Medical Devices3
What Employers Look For
The qualifications that appear most often in principal medical science liaison jobs.
- Advanced scientific degree (PharmD, MD, or PhD) in a relevant life sciences field
- Minimum five to eight years of field medical affairs or MSL experience
- Deep therapeutic area expertise in oncology, rare disease, or immunology
- Demonstrated KOL engagement and scientific exchange at a senior level
- Strong understanding of FDA promotional regulations and medical affairs compliance standards
- Experience contributing to medical strategy, advisory boards, or scientific platform development
Tips for Your Principal Medical Science Liaison Job Search
Tailor your CV to therapeutic area depth
Hiring managers for principal MSL roles prioritize deep scientific expertise over breadth. Lead your CV with your specific therapeutic area, name the disease states you've covered, and list publications or clinical trial work that demonstrates that depth.
Highlight cross-functional medical affairs contributions
Principal-level roles expect leadership beyond field work. Document your involvement in advisory boards, medical strategy, KOL development plans, or scientific platform development, since these distinguish you from standard MSL candidates and signal readiness for the step up.
Apply early to roles that fit
Migrate Mate lists principal medical science liaison openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Target companies by pipeline stage
Principal MSLs are often hired ahead of a product launch or major label expansion. Search for companies with late-stage Phase III assets or recent FDA approvals in your therapeutic area, as those employers have the strongest near-term need for senior field medical talent.
Prepare a scientific narrative for the platform interview
Most principal MSL interviews include a scientific platform presentation to a mock KOL panel. Rehearse translating dense clinical data into a clear, evidence-based narrative aimed at a specialist audience, and anticipate off-label questions that test your compliance instincts.
Negotiate territory scope and home-office setup
At the principal level, territory design and remote infrastructure matter as much as base compensation. Ask specifically about territory size, regional team structure, and whether the role has a defined path to a regional or national medical affairs position before you accept.
Principal Medical Science Liaison Jobs: Frequently Asked Questions
Which companies are hiring the most principal medical science liaisons?
Amgen, Syneos Health Commercial Solutions, and サイネオス・ヘルス are hiring the most principal medical science liaisons right now, with openings concentrated in California, Texas, and Massachusetts, based on current listings on Migrate Mate as of November 2026. Activity tends to cluster around companies with active late-stage pipelines or recent product approvals.
How many principal medical science liaison jobs are remote?
About 83% of principal medical science liaison openings are fully remote or hybrid as of November 2026, reflecting the inherently field-based nature of the role. Scientific platform and medical strategy responsibilities tend to allow more remote flexibility than territory coverage work, which still typically requires regional travel.
How do you become a principal medical science liaison?
Start by earning an advanced scientific degree such as a PharmD, MD, or PhD, then build field MSL experience in a defined therapeutic area. Develop a strong KOL network, contribute to medical strategy or advisory board planning, and take on mentorship or team lead responsibilities. Employers promoting to the principal level look for demonstrated scientific leadership beyond standard field engagement.
Can you get a principal medical science liaison role with limited MSL experience?
Moving directly into a principal MSL role without prior MSL experience is uncommon because the title signals senior field medical leadership. Candidates from clinical research, medical affairs consulting, or physician practice can compete if they demonstrate deep therapeutic area expertise, existing KOL relationships, and familiarity with regulatory boundaries around scientific exchange.
What does the principal medical science liaison interview process look like?
The process typically runs three to five rounds and includes a recruiter screen, a hiring manager interview focused on therapeutic area expertise and medical affairs strategy, a scientific platform presentation to a mock specialist audience, and a cross-functional panel with medical affairs, compliance, and commercial stakeholders. Some companies add a written case study or a KOL engagement scenario to assess scientific communication and compliance judgment.
Where can I find and apply to principal medical science liaison jobs?
You can find and apply to principal medical science liaison jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your therapeutic area and seniority, then apply directly to each listing that fits your background and target geography.
See All 438+ Principal Medical Science Liaison Jobs
Find roles that match your experience and apply in just a few clicks.
Find Jobs