Program Director Jobs in Boston, MA
Program Director jobs in Boston are concentrated in healthcare, higher education, and nonprofit management, with major openings in the Longwood Medical Area, Fenway, and downtown's Financial District. Employers currently hiring include Takeda Pharmaceuticals, North Suffolk Community Services, and Owl Labs. See the openings below and apply to the ones that match your experience.
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Job Description
Are you looking for a patient-focused, innovation-driven company to inspire you and empower you to shine? Join us as an Associate Director, Clinical Operations Program Lead based remotely reporting to the Senior Director, Clinical Operations.
At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to work towards their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, and work toward excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to provide Better Health and a Brighter Future to people around the world.
Here, you will be a necessary contributor to our inspiring, bold mission.
GOALS:
- Develop and lead the program-level operational strategy and planning on assigned programs in close collaboration with our strategic partners and other vendors.
- Represent Clinical Operations at the Global Program Team (GPT) and partner with Global Clinical Lead to lead the Clinical Sub Team (CST) accountable for the development and execution of the CDP.
- Provide program-level sponsor’s operational oversight of our strategic partners and other vendors to ensure the effective execution of the clinical studies on time, with high quality and within agreed budget.
ACCOUNTABILITIES:
- Accountable to the GPT for the translation of the CDP into an optimal operational strategy and plan. Ensures assessment of various scenarios operational for optimal execution of the CDP. Maintain close communication with the Global Program Leader and Global Clinical Lead to ensure expectations and activities are aligned.
- On assigned clinical programs, develop and lead the clinical program operational strategy in close collaboration with the Clinical Operations Managers (COMs), strategic partners, CROs, and other vendors.
- Serve as the point of escalation for the COMs for issues that can’t be resolved at the study level. Collaborate with COMs and cross-functional counterparts to oversee the performance of activities assigned to our strategic partners, CROs, and other vendors.
- Responsible for budget planning and accountable for external spend related to clinical program execution. Works closely with COMs, Global Program Manager (GPM), and Finance to ensure on a regular basis that budgets, enrolment, and gaiting are accurate.
- Responsible for participating in strategic cross-functional initiatives for process and/or business improvements.
- Communicates program status and issues to ensure timely decision-making by senior management.
- May participate in Business Development/in-licensing/alliances evaluations by providing operational due diligence.
- Review and provide expert clinical operations input into clinical documents related to the drug development process and into preparation for key regulatory meetings as appropriate.
- Leads Clinical Operations aspects of inspection readiness activities and acts as subject matter expert during regulatory inspections.
- Lead or participate in cross-functional strategic initiatives and process improvement.
- Actively seek new ways of working more efficiently to meet the needs of clinical development.
- Demonstrate advanced Takeda Leadership Behaviors and act as a role model for Takeda´s values.
EDUCATION AND EXPERIENCE:
Bachelor’s Degree or international equivalent required, Life Sciences preferred. Advanced degree is highly desirable.
10 or more years’ experience in pharmaceutical industry and/or clinical research organization, including 7 or more years clinical study/project management.
Experience must include early phase clinical studies/Phase 2 studies or later phase global programs.
Experience in more than one therapeutic area is highly desired.
Expertise in global regulatory and compliance requirements for clinical research, including but not limited to US CFR, EU CTD, and ICH GCP.
Awareness of local country requirements is also required
Demonstrated excellence in program management, including scenario assessment, risk assessment and contingency planning
Demonstrated excellent matrix leadership and communication skills
Able to influence without authority
Excellent teamwork, communication, organizational, interpersonal, conflict resolution and problem-solving skills
Entrepreneurial and innovative; takes measured risks; thinks outside the box; challenge the status quo
Pragmatic and willing to drive and support change
Is comfortable with ambiguity
Embody a culture of continual improvement and innovation; promote knowledge sharing
Fluent business English (oral and written)
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Massachusetts - VirtualU.S. Base Salary Range:
$154,400.00 - $242,550.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
Massachusetts - VirtualWorker Type
EmployeeWorker Sub-Type
RegularTime Type
Full timeJob Exempt
Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.#LI-Remote
See All 42 Program Director Jobs in Boston
Find roles in Boston that match your experience and apply in just a few clicks.
Find Program Director JobsProgram Director Job Market in Boston
Who's Hiring
- Takeda Pharmaceuticals7

- North Suffolk Community Services3

- Owl Labs2

- SimpliSafe2

- Centessa Pharmaceuticals2C
Top Industries Hiring
- Healthcare & Medical Services10
- Medical Devices6
- Technology & Software5
- Electronics & Hardware5
- Education4
Program Director Jobs in Boston: Frequently Asked Questions
How do I get a program director job in Boston?
Target the sectors that drive Boston's program director market: academic medical centers in the Longwood Medical Area, research universities along the Charles River corridor, and large nonprofits concentrated in Back Bay and the South End. Candidates who combine cross-functional leadership experience with familiarity in grant management, clinical operations, or research administration stand out. Networking through Boston's dense higher-education and healthcare communities also opens doors faster than applying cold.
Which companies hire program directors in Boston?
Companies currently hiring program directors in Boston include Takeda Pharmaceuticals, North Suffolk Community Services, and Owl Labs, per current listings on Migrate Mate as of June 2026. Boston's employer mix skews heavily toward academic hospitals, research institutions, universities, and mission-driven nonprofits, making it one of the more specialized program director markets in the country.
Are there remote program director jobs in Boston?
Yes, though availability depends heavily on the sector, since program directors in clinical, research, or campus-based roles are typically required on-site. About 38% of program director openings tied to Boston are remote or hybrid as of June 2026, with the most flexibility found in technology-adjacent program management and foundation or policy-focused roles.
How can I get a program director job in Boston with little or no experience?
The most realistic entry path in Boston is moving up from a program manager or program coordinator role within one of the city's large healthcare systems, universities, or nonprofits. Organizations in Longwood, Allston-Brighton, and Cambridge frequently hire coordinators and associate program managers who can grow into director-level positions internally. Demonstrating budget ownership, stakeholder management, and measurable program outcomes on your resume matters more than tenure in this market.
Which industries hire the most program directors in Boston?
The sectors hiring the most program directors in Boston are Healthcare & Medical Services, Medical Devices, and Technology & Software, based on current listings on Migrate Mate as of June 2026. Boston's concentration of world-class hospitals, research universities, and a deep nonprofit sector means demand for program directors is unusually strong and consistent compared to most U.S. cities.
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