Rare Disease Business Manager Jobs
Rare Disease Business Manager jobs are open across pharmaceutical, biotechnology, and specialty therapeutics companies, from associate and territory levels through senior and regional leadership, with specializations in orphan drug commercialization, patient access strategy, and rare disease account management. Find a role that fits from the openings below and apply directly.
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About This Role
The Global Medical Director, Rare Disease (SMA) Medical Education role is part of Rare Disease (SMA/ALS) Global Medical team, a strategic partner within Biogen that helps inform medical practice across our therapeutic areas and pipeline to improve meaningful patient outcomes. As a key member of this team the incumbent reports into to the Rare Disease (SMA/ALS) Global Medical Lead and is the accountable lead for shaping and driving the global medical education strategy for Biogen's Spinal Muscular Atrophy (SMA) portfolio — spanning marketed assets — in close collaboration with Clinical Development, the Product Development (PDC), regional/ICOE medical teams, and commercial/market access partners.
What You’ll Do
Strategy
Lead the long-range planning, development and execution of the Global SMA medical education strategy, tactics, and budget, advancing critical scientific narratives across regions and aligning with Biogen's Global Medical Plan and portfolio priorities.
Serve as the Global medical expert for the SMA portfolio, guiding lifecycle management and evidence strategy across the treatment journey.
Lead publication planning, KME/scientific engagement strategy and education plans for the SMA franchise, shaping treatment optimization and standard-of-care narratives ahead of evolving clinical practice.
Scientific Leadership
Provide medical oversight and direction across clinical development programs and lead scientific positioning and strategy.
Own the neurofilament light chain (NfL) narrative and biomarker positioning, driving alignment across initiatives, functions, and regions, and resolving inconsistencies in the scientific story.
Partner with Evidence Generation Medical Director on the global SMA evidence generation strategy, including real-world evidence, biomarker development, and registrational study support, in close collaboration and alignment with regional clinical experts and cross-functional partners.
Present data at global medical affairs events, including advisory boards, trainings, congresses, and medical education events; build and nurture relationships with external stakeholders (HCPs, healthcare institutions, advocacy groups) across the global SMA therapeutic landscape.
Governance & Execution
Serve as the global medical contact for key functions/stakeholders (e.g., Clinical Development, PDC, regional/ICOE medical teams, Commercial, Market Access, Legal/Compliance, Value & Evidence Generation) and as global medical lead for aligning processes, decision making, medical tactics, and metrics through a robust operating rhythm.
Provide medical review and direction across publications and scientific communications (abstracts, posters, manuscripts), Medical Information (including complex/non-standard escalations), and affiliate/regional support requests; reinforce and train governance processes for scientific narrative, publication content, and agency involvement.
Lead end-to-end planning and content development for global SMA medical symposia (e.g., the WMS Medical Symposium), including speaker engagement, contracting, and coordination with regional medical teams and cross-functional partners.
Lead medical training strategy and planning tied to congress readouts, new manuscript data, and key scientific topics, including delivery of training materials and support for related Q&A; contribute to development/adaptation of medical materials (presentations, briefs, talking points) per review requirements.
Co-lead recurring cross-functional medical forums, including a monthly meeting to align global SMA medical teams and a quarterly insights forum to synthesize medical insights and inform planning.
Leadership
Lead from where you are, coach each other, creating a positive team climate in alignment with Biogen's culture.
Who You Are
You are a scientific or clinical professional with a passion for science and deep scientific knowledge. You have a marked curiosity about healthcare and business opportunities. You keep patients, payers and physicians top of mind in your daily work and collaborate across regions to solve critical scientific and business challenges.
Required Skills
MD, PhD, PharmD or comparable advanced degree
Minimum of 8 years of pharmaceutical industry experience, preferably with prior work in regional/global roles. Substitution of industry work with relevant clinical practice experience in neuromuscular or rare disease may be considered.
Relevant experience in Rare Disease required (preferably SMA and/or neuromuscular disease)
Experience in developing medical education, evidence generation required
Experience and expertise with biomarker strategy, digital medical solutions, processes, and systems
Strong working knowledge of global regulations as relevant to Medical Affairs
Preferred Skills
Experience with medical launch as well as products at different stages of the lifecycle
Demonstrated ability to effectively lead and collaborate with global, regional, and/or affiliate medical teams to ensure regional activities are executed in alignment with global medical strategy and ensuring the insights and needs from them are known and properly addressed
Ability to manage projects and take initiative to solve complex and challenging problems
Experience managing and developing a global team of Medical Affairs professionals
Job Level: Management
Additional Information
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being ; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year Employee Resource Groups participation
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
About This Role
The Global Medical Director, Rare Disease (SMA) Medical Education role is part of Rare Disease (SMA/ALS) Global Medical team, a strategic partner within Biogen that helps inform medical practice across our therapeutic areas and pipeline to improve meaningful patient outcomes. As a key member of this team the incumbent reports into to the Rare Disease (SMA/ALS) Global Medical Lead and is the accountable lead for shaping and driving the global medical education strategy for Biogen's Spinal Muscular Atrophy (SMA) portfolio — spanning marketed assets — in close collaboration with Clinical Development, the Product Development (PDC), regional/ICOE medical teams, and commercial/market access partners.
What You’ll Do
Strategy
Lead the long-range planning, development and execution of the Global SMA medical education strategy, tactics, and budget, advancing critical scientific narratives across regions and aligning with Biogen's Global Medical Plan and portfolio priorities.
Serve as the Global medical expert for the SMA portfolio, guiding lifecycle management and evidence strategy across the treatment journey.
Lead publication planning, KME/scientific engagement strategy and education plans for the SMA franchise, shaping treatment optimization and standard-of-care narratives ahead of evolving clinical practice.
Scientific Leadership
Provide medical oversight and direction across clinical development programs and lead scientific positioning and strategy.
Own the neurofilament light chain (NfL) narrative and biomarker positioning, driving alignment across initiatives, functions, and regions, and resolving inconsistencies in the scientific story.
Partner with Evidence Generation Medical Director on the global SMA evidence generation strategy, including real-world evidence, biomarker development, and registrational study support, in close collaboration and alignment with regional clinical experts and cross-functional partners.
Present data at global medical affairs events, including advisory boards, trainings, congresses, and medical education events; build and nurture relationships with external stakeholders (HCPs, healthcare institutions, advocacy groups) across the global SMA therapeutic landscape.
Governance & Execution
Serve as the global medical contact for key functions/stakeholders (e.g., Clinical Development, PDC, regional/ICOE medical teams, Commercial, Market Access, Legal/Compliance, Value & Evidence Generation) and as global medical lead for aligning processes, decision making, medical tactics, and metrics through a robust operating rhythm.
Provide medical review and direction across publications and scientific communications (abstracts, posters, manuscripts), Medical Information (including complex/non-standard escalations), and affiliate/regional support requests; reinforce and train governance processes for scientific narrative, publication content, and agency involvement.
Lead end-to-end planning and content development for global SMA medical symposia (e.g., the WMS Medical Symposium), including speaker engagement, contracting, and coordination with regional medical teams and cross-functional partners.
Lead medical training strategy and planning tied to congress readouts, new manuscript data, and key scientific topics, including delivery of training materials and support for related Q&A; contribute to development/adaptation of medical materials (presentations, briefs, talking points) per review requirements.
Co-lead recurring cross-functional medical forums, including a monthly meeting to align global SMA medical teams and a quarterly insights forum to synthesize medical insights and inform planning.
Leadership
Lead from where you are, coach each other, creating a positive team climate in alignment with Biogen's culture.
Who You Are
You are a scientific or clinical professional with a passion for science and deep scientific knowledge. You have a marked curiosity about healthcare and business opportunities. You keep patients, payers and physicians top of mind in your daily work and collaborate across regions to solve critical scientific and business challenges.
Required Skills
MD, PhD, PharmD or comparable advanced degree
Minimum of 8 years of pharmaceutical industry experience, preferably with prior work in regional/global roles. Substitution of industry work with relevant clinical practice experience in neuromuscular or rare disease may be considered.
Relevant experience in Rare Disease required (preferably SMA and/or neuromuscular disease)
Experience in developing medical education, evidence generation required
Experience and expertise with biomarker strategy, digital medical solutions, processes, and systems
Strong working knowledge of global regulations as relevant to Medical Affairs
Preferred Skills
Experience with medical launch as well as products at different stages of the lifecycle
Demonstrated ability to effectively lead and collaborate with global, regional, and/or affiliate medical teams to ensure regional activities are executed in alignment with global medical strategy and ensuring the insights and needs from them are known and properly addressed
Ability to manage projects and take initiative to solve complex and challenging problems
Experience managing and developing a global team of Medical Affairs professionals
Job Level: Management
Additional Information
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being ; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year Employee Resource Groups participation
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
Rare Disease Business Manager Jobs by Experience Level
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Find JobsRare Disease Business Manager Job Market
Who's Hiring
- Taylor Strategy Partners25T
- Amgen20
- Takeda Pharmaceuticals19
- Alkermes12
- サイネオス・ヘルス7サ
Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Medical Devices
- Science & Research
- Healthcare & Medical Services
- Staffing & Recruiting
What Employers Look For
The qualifications that appear most often in rare disease business manager jobs.
- Minimum two to five years of specialty pharmaceutical or rare disease sales experience
- Demonstrated experience working with specialty pharmacies, patient hubs, and access programs
- Bachelor's degree in life sciences, business, or a related field
- Proven ability to engage key opinion leaders, academic medical centers, and specialists
- Strong understanding of payer landscape, prior authorization processes, and reimbursement pathways
- Proficiency with CRM platforms and ability to analyze territory data and sales reports
Tips for Your Rare Disease Business Manager Job Search
Tailor your resume for orphan drug context
Highlight any experience with low-prevalence conditions, rare disease patient advocacy, or small patient population commercialization. Hiring managers in this space weigh disease-area fluency heavily, so make your therapeutic knowledge visible, not buried in generic sales language.
Quantify access wins, not just revenue
Rare disease roles involve complex payer and hub navigation. Describe specific formulary wins, prior authorization pull-through results, or patient services program outcomes you drove. Generic quota attainment numbers mean less here than demonstrated access expertise.
Filter openings by therapeutic area first
Rare disease business manager roles vary widely by condition category, from lysosomal storage disorders to rare hematology to neuromuscular disease. Searching by disease area rather than title alone surfaces roles where your background gives you a real competitive edge.
Apply early to roles that fit
Migrate Mate lists rare disease business manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare case-based interview answers for access scenarios
Expect interviewers to present a scenario where a payer restricts access or a patient faces a coverage gap. Walk through your actual problem-solving process for those situations, referencing hub services, patient assistance programs, or specialty pharmacy coordination you have used.
Negotiate territory scope and support resources
Rare disease territories are often geographically large with small patient populations concentrated in academic medical centers. During offer negotiation, ask specifically about field reimbursement support, medical science liaison coverage, and patient services staffing in your geography.
Rare Disease Business Manager Jobs: Frequently Asked Questions
Which companies are hiring the most rare disease business managers?
The companies hiring the most rare disease business managers right now include Taylor Strategy Partners, Amgen, and Takeda Pharmaceuticals, with the largest share of openings in New Jersey, Texas, and Ohio, based on current listings on Migrate Mate as of August 2026. Rare disease hiring tends to cluster around companies with active orphan drug pipelines or recent rare disease product launches.
How many rare disease business manager jobs are remote?
About 86% of rare disease business manager openings are fully remote or hybrid as of August 2026, though field-based territory roles remain the dominant model in this specialty. Functions such as patient services strategy, national accounts support, and rare disease training roles are most likely to offer fully remote or hybrid arrangements.
How do you become a rare disease business manager?
Most rare disease business managers start with several years in specialty pharmaceutical sales before transitioning into rare disease. Building familiarity with a specific disease area, developing relationships with rare disease specialists and patient advocacy organizations, and gaining experience with hub services and prior authorization processes are the most direct paths into the role.
Can you get a rare disease business manager job with limited experience?
Breaking into rare disease without direct experience is competitive, but candidates who have worked in adjacent specialty areas such as oncology, neurology, or immunology, and who can demonstrate experience with complex payer access or specialty pharmacy navigation, are frequently considered. Showing deep disease-area knowledge and connections within the rare disease community can offset a shorter sales record.
What does the rare disease business manager interview process look like?
The process typically includes an initial phone screen with a recruiter, followed by a hiring manager video interview focused on rare disease experience and access case scenarios. Finalists usually complete a business plan presentation or ride-along assessment with a regional director. References and background checks occur before an offer is extended, and the full process commonly runs four to six weeks.
Where can I find and apply to rare disease business manager jobs?
You can find and apply to rare disease business manager jobs on Migrate Mate, which lists current openings from across the United States in one place. Search the available roles, find the ones that fit your experience and target geography, and apply directly to each listing from the page.
See All 130+ Rare Disease Business Manager Jobs
Find roles that match your experience and apply in just a few clicks.
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