Rare Disease Business Manager Jobs
Rare Disease Business Manager jobs are open across pharmaceutical, biotechnology, and specialty therapeutics companies, from associate and territory levels through senior and regional leadership, with specializations in orphan drug commercialization, patient access strategy, and rare disease account management. Find a role that fits from the openings below and apply directly.
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Job Description
About the Role:
The Rare Disease Business Manager (RDBM) is responsible for driving sales and territory growth through effective execution of sales strategies and tactics in a rare neurological sleep disorder, called narcolepsy type 1. This role involves collaboration with their Regional Business Leader and other cross-functional, customer-facing teams to ensure healthcare providers (HCPs) are well educated and that appropriate patients have access to a new therapeutic option, once approved by federal agencies. Reporting into a Regional Business Leader, the RDBM will support a new product introduction in a new therapeutic area for Takeda. Strong execution, insights gathering, and building our Company’s reputation will be critical to our success. The role will establish and build impactful relationships with targeted HCPs and accounts within their geographic territory. Following regulatory approval, the Rare Disease Business Manager will play a key role in generating demand for a new therapeutic option by focusing on educating and informing healthcare professionals by providing clinical information and in-depth knowledge of the product, the orexin system, and narcolepsy type 1.
How you will contribute:
- Results Focused: Demonstrates a strong sense of urgency to drive results and achieve strong performance by delivering a high level of sales effort will be necessary for a successful rare disease product introduction.
- Clinical Expertise: Possesses and delivers exceptional disease state, product knowledge, and selling skills in working with HCPs to support product education and drive demand.
- Sales Strategy and Execution: Following approval, drive sales by implementing sales and marketing plans, leveraging strong selling skills utilizing approved, on-label materials to achieve monthly, quarterly, and annual sales goals. Execute brand strategies and manage all business related activities within the assigned geographic territory, focusing on achieving sales goals and advancing the diagnosis and treatment of NT1.
- Specialty Customer Engagement: Builds strong relationships with, and educates healthcare professionals (HCPs), including sleep specialists, neurologists, pulmonologists, sleep centers and associated clinic staff, on disease state and approved Takeda orexin therapies.
- Strategic Analysis and Territory Planning: Strategically analyze local, regional, and national business trends and apply data to assess business opportunities and strategic priorities. Leverage market insights to appropriately tailor regional and local business strategies to market trends and customer needs.
- Communication Skills: Strong communication skills will be critical in discussions with specialty HCPs and accounts for a rare disease therapy. Utilize CRM system to document account profiles, develop pre-call plans and record post-call activities.
- Financial Responsibility: Manage a territory budget in a manner that is consistent with all Takeda compliance policies.
- Cross-Functional Collaboration: Partner with internal teams such as Patient Access, Market Access, Marketing to align on strategies and tactics that support customer and business outcomes. Collaborate with Sales and Marketing leadership to provide feedback that further supports sales tactics and performance. Foster a collaborative culture of accountability and engagement with cross-functional team members to enhance performance and impact.
- Compliance and Ethical Standards: Exemplify Takeda’s patient-first values and commitment to upholding high standards of customer satisfaction. Adhere strictly to all Takeda compliance policies, guidelines, training and relevant laws and regulations. Demonstrate leadership and integrity by seeking clarification when uncertain on compliance matters.
Expected skills (minimum education, knowledge or experience required to be successful in role)
Required:
- Bachelor’s degree – BS/BA.
- 3+ years of successful selling experience in pharmaceutical, biotech or medical device and/or relevant clinical or industry experience; OR 2+ years of successful selling experience at Takeda.
- Excellent verbal and written communication skills.
- Proven ability to navigate complex selling environment and influence across various decision makers in key accounts.
- Strong business acumen and strategic planning skills to identify and execute on selling opportunities.
- Demonstrated territory planning, strategic account management and prioritization skills. Ability to interpret analytical data to create effective sales strategies.
- Strong collaborative skills and ability to work within a matrix of cross functional partners on behalf of the customers served.
- Understanding of payer access and reimbursement at territory, regional, and state levels.
- Adaptability to changing market conditions and customer needs.
- Demonstrated learning agility with ability to successfully develop and compliantly apply clinical expertise and selling skills.
- Must reside within the territory or within close proximity to assigned geography.
Preferred:
- 5+ years of pharmaceutical sales experience, preferably in rare disease or sleep disorders.
- Sales experience with pharmaceutical or biologic products requiring coordination with patient access and market access teams.
- Relevant clinical or industry experience.
- Consultative / needs-based selling skills.
- Experience working in a highly regulated marketplace.
- Adept at leveraging emerging technologies, digital tools, and openness to AI-enabled processes.
LICENSES/CERTIFICATIONS:
- Valid Driver's License
TRAVEL REQUIREMENTS:
- Ability to drive and/or fly to accounts and occasional business meetings.
- Some overnight travel of up to 25-50% may be required depending on geographic assignment.
TRAINING REQUIREMENTS:
- This position and continued employment is contingent upon the employee successfully passing mandatory product training which includes written and oral examinations.
- External Takeda Hires Only: During that training period, the employee will be classified as a non-exempt employee and will be eligible for overtime during the training period only in accordance with applicable federal and/or state law but the employee will not be eligible for any Takeda related sales incentive programs and/or other production based bonuses. The training period will consist of live instruction, independent study, role play, and other training related activities which should take no more than 8 hours per day and 40 hours total in a workweek.
- After successful passage of the mandatory product training examinations, the employee will be transitioned to exempt status and will no longer be eligible for overtime. They will then be paid on a bi-weekly basis and eligible to participate in various Takeda related sales incentive programs and/or contests.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Connecticut - Virtual
U.S. Hourly Wage Range:
$66.11 - $90.91
The estimated hourly wage range reflects an anticipated range for this position. The actual hourly wage offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
Connecticut - Virtual
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Job Exempt
No
LI-Remote
Job Description
About the Role:
The Rare Disease Business Manager (RDBM) is responsible for driving sales and territory growth through effective execution of sales strategies and tactics in a rare neurological sleep disorder, called narcolepsy type 1. This role involves collaboration with their Regional Business Leader and other cross-functional, customer-facing teams to ensure healthcare providers (HCPs) are well educated and that appropriate patients have access to a new therapeutic option, once approved by federal agencies. Reporting into a Regional Business Leader, the RDBM will support a new product introduction in a new therapeutic area for Takeda. Strong execution, insights gathering, and building our Company’s reputation will be critical to our success. The role will establish and build impactful relationships with targeted HCPs and accounts within their geographic territory. Following regulatory approval, the Rare Disease Business Manager will play a key role in generating demand for a new therapeutic option by focusing on educating and informing healthcare professionals by providing clinical information and in-depth knowledge of the product, the orexin system, and narcolepsy type 1.
How you will contribute:
- Results Focused: Demonstrates a strong sense of urgency to drive results and achieve strong performance by delivering a high level of sales effort will be necessary for a successful rare disease product introduction.
- Clinical Expertise: Possesses and delivers exceptional disease state, product knowledge, and selling skills in working with HCPs to support product education and drive demand.
- Sales Strategy and Execution: Following approval, drive sales by implementing sales and marketing plans, leveraging strong selling skills utilizing approved, on-label materials to achieve monthly, quarterly, and annual sales goals. Execute brand strategies and manage all business related activities within the assigned geographic territory, focusing on achieving sales goals and advancing the diagnosis and treatment of NT1.
- Specialty Customer Engagement: Builds strong relationships with, and educates healthcare professionals (HCPs), including sleep specialists, neurologists, pulmonologists, sleep centers and associated clinic staff, on disease state and approved Takeda orexin therapies.
- Strategic Analysis and Territory Planning: Strategically analyze local, regional, and national business trends and apply data to assess business opportunities and strategic priorities. Leverage market insights to appropriately tailor regional and local business strategies to market trends and customer needs.
- Communication Skills: Strong communication skills will be critical in discussions with specialty HCPs and accounts for a rare disease therapy. Utilize CRM system to document account profiles, develop pre-call plans and record post-call activities.
- Financial Responsibility: Manage a territory budget in a manner that is consistent with all Takeda compliance policies.
- Cross-Functional Collaboration: Partner with internal teams such as Patient Access, Market Access, Marketing to align on strategies and tactics that support customer and business outcomes. Collaborate with Sales and Marketing leadership to provide feedback that further supports sales tactics and performance. Foster a collaborative culture of accountability and engagement with cross-functional team members to enhance performance and impact.
- Compliance and Ethical Standards: Exemplify Takeda’s patient-first values and commitment to upholding high standards of customer satisfaction. Adhere strictly to all Takeda compliance policies, guidelines, training and relevant laws and regulations. Demonstrate leadership and integrity by seeking clarification when uncertain on compliance matters.
Expected skills (minimum education, knowledge or experience required to be successful in role)
Required:
- Bachelor’s degree – BS/BA.
- 3+ years of successful selling experience in pharmaceutical, biotech or medical device and/or relevant clinical or industry experience; OR 2+ years of successful selling experience at Takeda.
- Excellent verbal and written communication skills.
- Proven ability to navigate complex selling environment and influence across various decision makers in key accounts.
- Strong business acumen and strategic planning skills to identify and execute on selling opportunities.
- Demonstrated territory planning, strategic account management and prioritization skills. Ability to interpret analytical data to create effective sales strategies.
- Strong collaborative skills and ability to work within a matrix of cross functional partners on behalf of the customers served.
- Understanding of payer access and reimbursement at territory, regional, and state levels.
- Adaptability to changing market conditions and customer needs.
- Demonstrated learning agility with ability to successfully develop and compliantly apply clinical expertise and selling skills.
- Must reside within the territory or within close proximity to assigned geography.
Preferred:
- 5+ years of pharmaceutical sales experience, preferably in rare disease or sleep disorders.
- Sales experience with pharmaceutical or biologic products requiring coordination with patient access and market access teams.
- Relevant clinical or industry experience.
- Consultative / needs-based selling skills.
- Experience working in a highly regulated marketplace.
- Adept at leveraging emerging technologies, digital tools, and openness to AI-enabled processes.
LICENSES/CERTIFICATIONS:
- Valid Driver's License
TRAVEL REQUIREMENTS:
- Ability to drive and/or fly to accounts and occasional business meetings.
- Some overnight travel of up to 25-50% may be required depending on geographic assignment.
TRAINING REQUIREMENTS:
- This position and continued employment is contingent upon the employee successfully passing mandatory product training which includes written and oral examinations.
- External Takeda Hires Only: During that training period, the employee will be classified as a non-exempt employee and will be eligible for overtime during the training period only in accordance with applicable federal and/or state law but the employee will not be eligible for any Takeda related sales incentive programs and/or other production based bonuses. The training period will consist of live instruction, independent study, role play, and other training related activities which should take no more than 8 hours per day and 40 hours total in a workweek.
- After successful passage of the mandatory product training examinations, the employee will be transitioned to exempt status and will no longer be eligible for overtime. They will then be paid on a bi-weekly basis and eligible to participate in various Takeda related sales incentive programs and/or contests.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Connecticut - Virtual
U.S. Hourly Wage Range:
$66.11 - $90.91
The estimated hourly wage range reflects an anticipated range for this position. The actual hourly wage offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
Connecticut - Virtual
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Job Exempt
No
LI-Remote
See All Rare Disease Business Manager Jobs
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Find JobsRare Disease Business Manager Job Market
A snapshot from current openings nationwide, updated as new roles post.
Who's Hiring
- Takeda Pharmaceuticals5
- Otsuka2
- Horizon Therapeutics Usa1
Top Industries Hiring
- Biotechnology & Pharmaceuticals5
- Medical Devices2
- Science & Research1
What Employers Look For
The qualifications that appear most often in rare disease business manager jobs.
- Minimum two to five years of specialty pharmaceutical or rare disease sales experience
- Demonstrated experience working with specialty pharmacies, patient hubs, and access programs
- Bachelor's degree in life sciences, business, or a related field
- Proven ability to engage key opinion leaders, academic medical centers, and specialists
- Strong understanding of payer landscape, prior authorization processes, and reimbursement pathways
- Proficiency with CRM platforms and ability to analyze territory data and sales reports
Tips for Your Rare Disease Business Manager Job Search
Tailor your resume for orphan drug context
Highlight any experience with low-prevalence conditions, rare disease patient advocacy, or small patient population commercialization. Hiring managers in this space weigh disease-area fluency heavily, so make your therapeutic knowledge visible, not buried in generic sales language.
Quantify access wins, not just revenue
Rare disease roles involve complex payer and hub navigation. Describe specific formulary wins, prior authorization pull-through results, or patient services program outcomes you drove. Generic quota attainment numbers mean less here than demonstrated access expertise.
Filter openings by therapeutic area first
Rare disease business manager roles vary widely by condition category, from lysosomal storage disorders to rare hematology to neuromuscular disease. Searching by disease area rather than title alone surfaces roles where your background gives you a real competitive edge.
Apply early to roles that fit
Migrate Mate lists rare disease business manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare case-based interview answers for access scenarios
Expect interviewers to present a scenario where a payer restricts access or a patient faces a coverage gap. Walk through your actual problem-solving process for those situations, referencing hub services, patient assistance programs, or specialty pharmacy coordination you have used.
Negotiate territory scope and support resources
Rare disease territories are often geographically large with small patient populations concentrated in academic medical centers. During offer negotiation, ask specifically about field reimbursement support, medical science liaison coverage, and patient services staffing in your geography.
Rare Disease Business Manager Jobs: Frequently Asked Questions
How many rare disease business manager jobs are remote?
About 75% of rare disease business manager openings are fully remote or hybrid as of June 2026, though field-based territory roles remain the dominant model in this specialty. Functions such as patient services strategy, national accounts support, and rare disease training roles are most likely to offer fully remote or hybrid arrangements.
How do you become a rare disease business manager?
Most rare disease business managers start with several years in specialty pharmaceutical sales before transitioning into rare disease. Building familiarity with a specific disease area, developing relationships with rare disease specialists and patient advocacy organizations, and gaining experience with hub services and prior authorization processes are the most direct paths into the role.
Can you get a rare disease business manager job with limited experience?
Breaking into rare disease without direct experience is competitive, but candidates who have worked in adjacent specialty areas such as oncology, neurology, or immunology, and who can demonstrate experience with complex payer access or specialty pharmacy navigation, are frequently considered. Showing deep disease-area knowledge and connections within the rare disease community can offset a shorter sales record.
What does the rare disease business manager interview process look like?
The process typically includes an initial phone screen with a recruiter, followed by a hiring manager video interview focused on rare disease experience and access case scenarios. Finalists usually complete a business plan presentation or ride-along assessment with a regional director. References and background checks occur before an offer is extended, and the full process commonly runs four to six weeks.
Where can I find and apply to rare disease business manager jobs?
You can find and apply to rare disease business manager jobs on Migrate Mate, which lists current openings from across the United States in one place. Search the available roles, find the ones that fit your experience and target geography, and apply directly to each listing from the page.
See All Rare Disease Business Manager Jobs
Jump back to the full list of openings and apply to any rare disease business manager role that fits.
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