Rare Disease Business Manager Jobs
Rare Disease Business Manager jobs are open across pharmaceutical, biotechnology, and specialty therapeutics companies, from associate and territory levels through senior and regional leadership, with specializations in orphan drug commercialization, patient access strategy, and rare disease account management. Find a role that fits from the openings below and apply directly.
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Territory includes Lakeland and surrounding areas.
Relocation is not offered for this role.
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Account Manager/Specialty Account Manager – Tavneos
Live
What you will do
Let’s do this. Let’s change the world. We are seeking an Account Manager/Specialty Account Manager to complete commercial activities for the assigned geography and establish relationships with customers to drive demand for Tavneos (avacopan) in approved patients. Tavneos is indicated as an adjunctive treatment of adult patients with severe active anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (granulomatosis with polyangiitis [GPA] and microscopic polyangiitis [MPA]) in combination with standard therapy including glucocorticoids.
This role is field based and will require gaining access to customers in a clinic OR hospital setting while also enhancing your ability to engage through digital channels.
The RD AM/SAM will be responsible for product performance at a territory level, expected to be a disease category expert, a product champion, provide account management support, and exhibit business knowledge of the local landscape to assess key stakeholders plus future trends within the marketplace.
Responsibilities include:
- Proficiency in both live and virtual customer engagements
- Develop a comprehensive and effective territory business plan aimed at achieving and exceeding annual goals established by commercial leadership
- Ability to engage all partners around patient ecosystem – caregivers, HCPs, case managers, nurses, infusion centers, etc. in multiple settings of care-Hospital, Clinic, etc.
- Able to effectively collaborate across all corporate functions-MSLs, TLLs, Field Access Team, supporting sales teams, etc.
- Channel patients to treatment: Crafting referral networks to both existing centers of excellence, as well as, setting up new treatment CoEs.
- Building long-term relationships across multiple stakeholders and senior decision-makers, both inside and outside of Amgen, and sustaining extensive and rich networks to advance business partnerships and deep customer relationships.
- Ability to build broader disease awareness beyond the expert (i.e., with patients, GPs)
- Identifies drivers/barriers and coordinates pull-through initiatives across field teams
- Provides actionable field intelligence and recommendations to Amgen home office
- Partners closely with Market Access Team Account Executives in shared accounts.
- Promote Tavneos within approved labeling in a comprehensive, fair and ethical manner that is consistent with industry specific and corporate legal and regulatory guidelines
- Develop strong customer relationships by better understanding the customer’s needs
- Serves as a resource/consultant to customers and staff regarding payer policies and processes (eligibility and benefit verification, prior-authorization and appeals/denials)
- Improve use of marketing resources to maintain and develop customer relationships for the purpose of growing the customers’ confidence to prescribe Amgen medications for appropriate patients
- Communicates territory activity in an accurate and timely manner as directed by management
- Provides feedback to sales and commercial leadership, marketing colleagues, and other internal departments about changing environment and other internal departments
- Successfully completes all training classes
- Completes administrative duties in an accurate and timely fashion
- Manages efforts within assigned promotional budget
- Attends medical congresses and society meetings as needed
- Ensures timely access for patients through patient services and savings programs
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The Specialty Account Manager we seek is a motivated professional with these qualifications.
Basic Qualifications (Account Manager – Level 4)
- Bachelor's Degree and 3 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience OR
- Associate degree and 6 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience OR
- High school diploma/GED and 8 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience
Basic Qualifications (Specialty Account Manager – Level 5)
- Doctorate degree & 2 years of collective account management experience, sales, & commercial experience OR
- Master’s degree & 6 years of collective account management experience, sales, & commercial experience OR
- Bachelor’s degree & 8 years of collective account management experience, sales, & commercial experience OR
- Associate degree & 10 years of collective account management experience, sales, & commercial experience
Preferred Qualifications:
- Prior experience in rheumatology, nephrology, and/or the rare disease space.
- Consistent track record of access creation in managed markets
- Working knowledge of geography including existing relationships with key customers
- Prior experience developing and implementing critical initiatives with cross-functional Business Units that successfully enable access and demand creation in key accounts
- Prior experience working with Medical Science Liaisons (MSLs), HOPE MSLs, Medical platform or policy development and opinion leader engagement
- Strong communication and presentation skills including experience with executive-level audiences
- Excellent negotiation skills
- Strong analytical skills/eye for business
- Demonstrated ability to take initiative, impart energy and enthusiasm, and work in teams
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is (Account Manager – Level 4) $145,311 - $196,597 (Specialty Account Manager – Level 5) $158,931 - $215,025. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
- Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans and bi-annual company-wide shutdowns
- Flexible work models, including remote work arrangements, where possible
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Application deadline
Amgen's application deadline is 11/30 for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
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Find JobsRare Disease Business Manager Job Market
Who's Hiring
- Amgen146

- Taylor Strategy Partners21

- Syneos Health Commercial Solutions15

- サイネオス・ヘルス12

- Takeda Pharmaceuticals11

Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Healthcare & Medical Services
What Employers Look For
The qualifications that appear most often in rare disease business manager jobs.
- Minimum two to five years of specialty pharmaceutical or rare disease sales experience
- Demonstrated experience working with specialty pharmacies, patient hubs, and access programs
- Bachelor's degree in life sciences, business, or a related field
- Proven ability to engage key opinion leaders, academic medical centers, and specialists
- Strong understanding of payer landscape, prior authorization processes, and reimbursement pathways
- Proficiency with CRM platforms and ability to analyze territory data and sales reports
Tips for Your Rare Disease Business Manager Job Search
Tailor your resume for orphan drug context
Highlight any experience with low-prevalence conditions, rare disease patient advocacy, or small patient population commercialization. Hiring managers in this space weigh disease-area fluency heavily, so make your therapeutic knowledge visible, not buried in generic sales language.
Quantify access wins, not just revenue
Rare disease roles involve complex payer and hub navigation. Describe specific formulary wins, prior authorization pull-through results, or patient services program outcomes you drove. Generic quota attainment numbers mean less here than demonstrated access expertise.
Filter openings by therapeutic area first
Rare disease business manager roles vary widely by condition category, from lysosomal storage disorders to rare hematology to neuromuscular disease. Searching by disease area rather than title alone surfaces roles where your background gives you a real competitive edge.
Apply early to roles that fit
Migrate Mate lists rare disease business manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare case-based interview answers for access scenarios
Expect interviewers to present a scenario where a payer restricts access or a patient faces a coverage gap. Walk through your actual problem-solving process for those situations, referencing hub services, patient assistance programs, or specialty pharmacy coordination you have used.
Negotiate territory scope and support resources
Rare disease territories are often geographically large with small patient populations concentrated in academic medical centers. During offer negotiation, ask specifically about field reimbursement support, medical science liaison coverage, and patient services staffing in your geography.
Rare Disease Business Manager Jobs: Frequently Asked Questions
Which companies are hiring the most rare disease business managers?
The companies hiring the most rare disease business managers right now include Amgen, Taylor Strategy Partners, and Syneos Health Commercial Solutions, with the largest share of openings in California, Massachusetts, and Florida, based on current listings on Migrate Mate as of November 2026. Rare disease hiring tends to cluster around companies with active orphan drug pipelines or recent rare disease product launches.
How many rare disease business manager jobs are remote?
About 81% of rare disease business manager openings are fully remote or hybrid as of November 2026, though field-based territory roles remain the dominant model in this specialty. Functions such as patient services strategy, national accounts support, and rare disease training roles are most likely to offer fully remote or hybrid arrangements.
How do you become a rare disease business manager?
Most rare disease business managers start with several years in specialty pharmaceutical sales before transitioning into rare disease. Building familiarity with a specific disease area, developing relationships with rare disease specialists and patient advocacy organizations, and gaining experience with hub services and prior authorization processes are the most direct paths into the role.
Can you get a rare disease business manager job with limited experience?
Breaking into rare disease without direct experience is competitive, but candidates who have worked in adjacent specialty areas such as oncology, neurology, or immunology, and who can demonstrate experience with complex payer access or specialty pharmacy navigation, are frequently considered. Showing deep disease-area knowledge and connections within the rare disease community can offset a shorter sales record.
What does the rare disease business manager interview process look like?
The process typically includes an initial phone screen with a recruiter, followed by a hiring manager video interview focused on rare disease experience and access case scenarios. Finalists usually complete a business plan presentation or ride-along assessment with a regional director. References and background checks occur before an offer is extended, and the full process commonly runs four to six weeks.
Where can I find and apply to rare disease business manager jobs?
You can find and apply to rare disease business manager jobs on Migrate Mate, which lists current openings from across the United States in one place. Search the available roles, find the ones that fit your experience and target geography, and apply directly to each listing from the page.
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