Rare Disease Business Manager Jobs
Rare Disease Business Manager jobs are open across pharmaceutical, biotechnology, and specialty therapeutics companies, from associate and territory levels through senior and regional leadership, with specializations in orphan drug commercialization, patient access strategy, and rare disease account management. Find a role that fits from the openings below and apply directly.
Find JobsLooking for remote work? View remote rare disease business manager jobs →Overview
Showing 5 of 172+ Rare Disease Business Manager jobs
Specialty Account Manager, Endocrinology (Rare Disease)
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
What you will do
Let’s do this. Let’s change the world. In this vital role you will be responsible for representing Amgen products to physicians and healthcare professionals, establishing product sales, and performing total territory account management. This includes providing disease information and education to medical professionals and all external customers involved in the care of patients.
- Consistently achieve assigned sales objectives through the promotion of patient-centered disease and product education to HCPs to improve patient care while adhering to corporate compliance guidelines
- Implement goals of the marketing plan through execution of strategic account business plan.
- Demonstrated experience working in a matrix environment, which will encompass Case Managers, Medical Affairs, Patient access team, and other parties as deemed necessary.
- Effectively utilize all available resources and programs including peer to peer education and cross functional partners within the company to address identified knowledge gaps
- Proven ability to navigate and identify opportunities through the healthcare landscape including academic institutions, IDNs, accountable care organizations, private practices, and community hospital systems
- Establish productive business relationships with key local, regional, and national KOLs within the geographical coverage area and assigned therapeutic areas.
- Develops and maintains a high-level, in-depth disease and therapeutic clinical and scientific knowledge.
- Utilize a consultative selling approach involving a highly technical, solution oriented selling technique enabling the specialist to meet the needs of healthcare professionals Rare Disease patients.
- Execute all of the above with a strong understanding and adherence to compliance and corporate policies including appropriate documentation and reporting.
Win
What we expect of you:
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a person with these qualifications.
Basic Qualifications (Account Manager – Level 4)
Bachelor's Degree and 3 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience
OR
Associate degree and 6 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience
OR
High school diploma/GED and 8 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience
Basic Qualifications (Specialty Account Manager – Level 5)
Doctorate degree & 2 years of collective account management experience, sales, & commercial experience
OR
Master’s degree & 6 years of collective account management experience, sales, & commercial experience
OR
Bachelor’s degree & 8 years of collective account management experience, sales, & commercial experience
OR
Associate degree & 10 years of collective account management experience, sales, & commercial experience
- Bachelor's degree strongly preferred; Graduate business or healthcare related degree preferred.
- 7+ experience in biotech, specialty pharmaceutical, or rare disease sales.
- 3+ years of experience in one or more of the following:
- Rare disease/orphan drug experience; ultra-orphan preferred; Rare disease launch experience strongly preferred
- Nephrology experience preferred
- At least 3 years of in office injection/infusion sales selling a product that is a medical benefit requiring extensive coordination with patient access services.
- Previous experience operating in a matrix selling environment collaborating with patient services, market access, medical affairs, and reimbursement with significant focus on patient centricity.
- Market development / deep profiling in rare, unmet spaces experience preferred.
- Demonstrated success educating HCPs about complex diseases diagnosed through clinical observation involving diverse patient profiles that do not always lend themselves to simple segmentation diagnosis.
- Documented track record of delivering consistent, exceptional levels of performance.
- Proven ability to work independently in a fast-paced, highly challenging work environment.
- Excellent written and verbal communication skills.
- Strong organizational, analytical and computer skills required
- Proficient in Microsoft Office.
- Professional, proactive demeanor.
- Strong interpersonal skills.
- Requires approximately 20-30% travel, including some overnight and weekend commitments.
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is (Account Manager – Level 4) $145,311 - $196,597 (Specialty Account Manager – Level 5) $158,931 - $215,025. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
- Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans and bi-annual company-wide shutdowns
- Flexible work models, including remote work arrangements, where possible
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Application deadline
There is no application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Specialty Account Manager, Endocrinology (Rare Disease)
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
What you will do
Let’s do this. Let’s change the world. In this vital role you will be responsible for representing Amgen products to physicians and healthcare professionals, establishing product sales, and performing total territory account management. This includes providing disease information and education to medical professionals and all external customers involved in the care of patients.
- Consistently achieve assigned sales objectives through the promotion of patient-centered disease and product education to HCPs to improve patient care while adhering to corporate compliance guidelines
- Implement goals of the marketing plan through execution of strategic account business plan.
- Demonstrated experience working in a matrix environment, which will encompass Case Managers, Medical Affairs, Patient access team, and other parties as deemed necessary.
- Effectively utilize all available resources and programs including peer to peer education and cross functional partners within the company to address identified knowledge gaps
- Proven ability to navigate and identify opportunities through the healthcare landscape including academic institutions, IDNs, accountable care organizations, private practices, and community hospital systems
- Establish productive business relationships with key local, regional, and national KOLs within the geographical coverage area and assigned therapeutic areas.
- Develops and maintains a high-level, in-depth disease and therapeutic clinical and scientific knowledge.
- Utilize a consultative selling approach involving a highly technical, solution oriented selling technique enabling the specialist to meet the needs of healthcare professionals Rare Disease patients.
- Execute all of the above with a strong understanding and adherence to compliance and corporate policies including appropriate documentation and reporting.
Win
What we expect of you:
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a person with these qualifications.
Basic Qualifications (Account Manager – Level 4)
Bachelor's Degree and 3 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience
OR
Associate degree and 6 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience
OR
High school diploma/GED and 8 years of sales experience within pharmaceutical, biotech or medical device industry or hospital sales experience
Basic Qualifications (Specialty Account Manager – Level 5)
Doctorate degree & 2 years of collective account management experience, sales, & commercial experience
OR
Master’s degree & 6 years of collective account management experience, sales, & commercial experience
OR
Bachelor’s degree & 8 years of collective account management experience, sales, & commercial experience
OR
Associate degree & 10 years of collective account management experience, sales, & commercial experience
- Bachelor's degree strongly preferred; Graduate business or healthcare related degree preferred.
- 7+ experience in biotech, specialty pharmaceutical, or rare disease sales.
- 3+ years of experience in one or more of the following:
- Rare disease/orphan drug experience; ultra-orphan preferred; Rare disease launch experience strongly preferred
- Nephrology experience preferred
- At least 3 years of in office injection/infusion sales selling a product that is a medical benefit requiring extensive coordination with patient access services.
- Previous experience operating in a matrix selling environment collaborating with patient services, market access, medical affairs, and reimbursement with significant focus on patient centricity.
- Market development / deep profiling in rare, unmet spaces experience preferred.
- Demonstrated success educating HCPs about complex diseases diagnosed through clinical observation involving diverse patient profiles that do not always lend themselves to simple segmentation diagnosis.
- Documented track record of delivering consistent, exceptional levels of performance.
- Proven ability to work independently in a fast-paced, highly challenging work environment.
- Excellent written and verbal communication skills.
- Strong organizational, analytical and computer skills required
- Proficient in Microsoft Office.
- Professional, proactive demeanor.
- Strong interpersonal skills.
- Requires approximately 20-30% travel, including some overnight and weekend commitments.
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is (Account Manager – Level 4) $145,311 - $196,597 (Specialty Account Manager – Level 5) $158,931 - $215,025. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
- Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans and bi-annual company-wide shutdowns
- Flexible work models, including remote work arrangements, where possible
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Application deadline
There is no application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Rare Disease Business Manager Jobs by Experience Level
See All 172+ Rare Disease Business Manager Jobs
Find roles that match your experience and apply in just a few clicks.
Find JobsRare Disease Business Manager Job Market
Who's Hiring
- Taylor Strategy Partners51
- Amgen25
- サイネオス・ヘルス19
- Takeda Pharmaceuticals17
- Syneos Health Commercial Solutions16
Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Medical Devices
What Employers Look For
The qualifications that appear most often in rare disease business manager jobs.
- Minimum two to five years of specialty pharmaceutical or rare disease sales experience
- Demonstrated experience working with specialty pharmacies, patient hubs, and access programs
- Bachelor's degree in life sciences, business, or a related field
- Proven ability to engage key opinion leaders, academic medical centers, and specialists
- Strong understanding of payer landscape, prior authorization processes, and reimbursement pathways
- Proficiency with CRM platforms and ability to analyze territory data and sales reports
Tips for Your Rare Disease Business Manager Job Search
Tailor your resume for orphan drug context
Highlight any experience with low-prevalence conditions, rare disease patient advocacy, or small patient population commercialization. Hiring managers in this space weigh disease-area fluency heavily, so make your therapeutic knowledge visible, not buried in generic sales language.
Quantify access wins, not just revenue
Rare disease roles involve complex payer and hub navigation. Describe specific formulary wins, prior authorization pull-through results, or patient services program outcomes you drove. Generic quota attainment numbers mean less here than demonstrated access expertise.
Filter openings by therapeutic area first
Rare disease business manager roles vary widely by condition category, from lysosomal storage disorders to rare hematology to neuromuscular disease. Searching by disease area rather than title alone surfaces roles where your background gives you a real competitive edge.
Apply early to roles that fit
Migrate Mate lists rare disease business manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare case-based interview answers for access scenarios
Expect interviewers to present a scenario where a payer restricts access or a patient faces a coverage gap. Walk through your actual problem-solving process for those situations, referencing hub services, patient assistance programs, or specialty pharmacy coordination you have used.
Negotiate territory scope and support resources
Rare disease territories are often geographically large with small patient populations concentrated in academic medical centers. During offer negotiation, ask specifically about field reimbursement support, medical science liaison coverage, and patient services staffing in your geography.
Rare Disease Business Manager Jobs: Frequently Asked Questions
Which companies are hiring the most rare disease business managers?
The companies hiring the most rare disease business managers right now include Taylor Strategy Partners, Amgen, and サイネオス・ヘルス, with the largest share of openings in California, Massachusetts, and North Carolina, based on current listings on Migrate Mate as of September 2026. Rare disease hiring tends to cluster around companies with active orphan drug pipelines or recent rare disease product launches.
How many rare disease business manager jobs are remote?
About 91% of rare disease business manager openings are fully remote or hybrid as of September 2026, though field-based territory roles remain the dominant model in this specialty. Functions such as patient services strategy, national accounts support, and rare disease training roles are most likely to offer fully remote or hybrid arrangements.
How do you become a rare disease business manager?
Most rare disease business managers start with several years in specialty pharmaceutical sales before transitioning into rare disease. Building familiarity with a specific disease area, developing relationships with rare disease specialists and patient advocacy organizations, and gaining experience with hub services and prior authorization processes are the most direct paths into the role.
Can you get a rare disease business manager job with limited experience?
Breaking into rare disease without direct experience is competitive, but candidates who have worked in adjacent specialty areas such as oncology, neurology, or immunology, and who can demonstrate experience with complex payer access or specialty pharmacy navigation, are frequently considered. Showing deep disease-area knowledge and connections within the rare disease community can offset a shorter sales record.
What does the rare disease business manager interview process look like?
The process typically includes an initial phone screen with a recruiter, followed by a hiring manager video interview focused on rare disease experience and access case scenarios. Finalists usually complete a business plan presentation or ride-along assessment with a regional director. References and background checks occur before an offer is extended, and the full process commonly runs four to six weeks.
Where can I find and apply to rare disease business manager jobs?
You can find and apply to rare disease business manager jobs on Migrate Mate, which lists current openings from across the United States in one place. Search the available roles, find the ones that fit your experience and target geography, and apply directly to each listing from the page.
See All 172+ Rare Disease Business Manager Jobs
Find roles that match your experience and apply in just a few clicks.
Find Jobs