Registered Nurse Jobs in Indianapolis, IN
Registered Nurse jobs in Indianapolis are concentrated across the city's major medical corridor near the IUPUI campus, the Meridian-Kessler area, and downtown, with strong demand in acute care, critical care, and home health. Top employers hiring right now include Ascension, Indiana University Health, and American Traveler. Find a role that fits below and apply directly.
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- Perform scrub functions including the selection and handling of instruments and supplies used during procedure.
- Perform circulating functions including monitoring, recording and communicating patient condition and managing overall nursing care of patient before, during and after procedure.
- Directly assist operating physician with surgical tasks including hemostasis, suturing and wound exposure as well as patient positioning.
- Prepare operating rooms and surgical instruments and equipment for use.
- Registered Nurse credentialed from the Indiana Board of Nursing obtained prior to hire date or job transfer date required.
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One or more of the following required:
- Advanced Life Support obtained within 6 Months (180 days) of hire date or job transfer date. American Heart Association or American Red Cross accepted.
- BLS Provider obtained within 1 Month (30 days) of hire date or job transfer date. American Heart Association or American Red Cross accepted.
- Diploma from an accredited school/college of nursing OR required professional licensure at time of hire.
Equal employment opportunity employer
Ascension provides Equal Employment Opportunities (EEO) to all associates and applicants for employment without regard to race, color, religion, sex/gender, sexual orientation, gender identity or expression, pregnancy, childbirth, and related medical conditions, lactation, breastfeeding, national origin, citizenship, age, disability, genetic information, veteran status, marital status, all as defined by applicable law, and any other legally protected status or characteristic in accordance with applicable federal, state and local laws. For further information, view the EEO Know Your Rights (English) poster or EEO Know Your Rights (Spanish) poster.
Fraud prevention notice
Prospective applicants should be vigilant against fraudulent job offers and interview requests. Scammers may use sophisticated tactics to impersonate Ascension employees. To ensure your safety, please remember: Ascension will never ask for payment or to provide banking or financial information as part of the job application or hiring process. Our legitimate email communications will always come from an @ascension.org email address; do not trust other domains, and an official offer will only be extended to candidates who have completed a job application through our authorized applicant tracking system.
E-Verify statement
Benefits:
Various health insurance options & wellness plans
Retirement benefits including employer match plans
Long-term & short-term disability
Employee assistance programs (EAP)
Parental leave & adoption assistance
Tuition reimbursement
Ways to give back to your community
Benefit options and eligibility vary by position. Compensation varies based on factors including, but not limited to, experience, skills, education, performance, location and salary range at the time of the offer.
See All 99 Registered Nurse Jobs in Indianapolis
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Find Registered Nurse JobsRegistered Nurse Job Market in Indianapolis
Who's Hiring
- Ascension25

- Indiana University Health12

- American Traveler8

- Franciscan Health8

- Community Health Network8

Top Industries Hiring
- Healthcare & Medical Services
Registered Nurse Jobs in Indianapolis: Frequently Asked Questions
How do I get a registered nurse job in Indianapolis?
Indianapolis hiring concentrates in its large health system networks, long-term care facilities along the north side, and outpatient clinics expanding through Fishers and Carmel. Candidates with ICU, med-surg, or emergency department experience move fastest in this market. Specializing in a high-demand area like critical care or oncology, and targeting the academic medical centers near downtown, gives you a clear edge over generalist applicants.
Which companies hire registered nurses in Indianapolis?
Indianapolis registered nurse roles are posted by Ascension, Indiana University Health, and American Traveler and others right now, based on current listings on Migrate Mate as of August 2026. The local market is anchored by large hospital systems, multi-site outpatient groups, and a growing number of specialty care and rehabilitation providers serving Marion County and its surrounding suburbs.
Are there remote registered nurse jobs in Indianapolis?
Yes, though remote opportunities are limited by nature since most registered nurse roles require direct patient contact. About 19% of registered nurse openings tied to Indianapolis are remote or hybrid as of August 2026, concentrated in telehealth triage, utilization review, and case management roles. Indianapolis-based insurance carriers and managed care organizations are the most consistent source of those fully remote positions.
How can I get a registered nurse job in Indianapolis with little or no experience?
The most realistic entry path in Indianapolis is a new graduate residency program, which the city's large academic medical centers and regional hospital systems run on a structured cohort basis. Community hospitals on the east and south sides of Marion County tend to have more open new-grad slots than the flagship downtown facilities. Securing a PCT or CNA role at a target employer first is a proven way to move into a staff RN position once licensed.
Which industries hire the most registered nurses in Indianapolis?
The sectors hiring the most registered nurses in Indianapolis are Healthcare & Medical Services, based on current listings on Migrate Mate as of August 2026. Indianapolis's role as a regional medical hub and home to several major insurers and pharmaceutical companies creates layered demand well beyond traditional hospital settings.
See All 99 Registered Nurse Jobs in Indianapolis
Find roles in Indianapolis that match your experience and apply in just a few clicks.
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