Senior Level Regulatory Affairs Director Jobs
Senior level regulatory affairs director jobs place experienced professionals in charge of regulatory strategy, cross-functional submission programs, and the teams that drive agency approvals. Openings concentrate across Biotechnology & Pharmaceuticals, Medical Devices, and Science & Research, with a mix of on-site, hybrid, and remote positions available, and employers like Revolution Medicines, Revolution Medicines, and Insmed Incorporated hiring at this level now.
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Responsibilities:
Regulatory Affairs Liaison: Communication with Regulators and Bank Management
- Serve as the primary liaison with regulatory agencies and the Bank during periodic examinations and BAU or ad hoc inquiries; facilitate prompt review and approval of submissions and commitment closures
- Oversee the bank examination process for exams and enhanced continuous monitoring reviews conducted by the different U.S. regulatory authorities
- Lead in maintaining fluid and regular communications between the Bank and its regulators
- Convey regulators’ inquiry/advice/comments/instruction/concerns to relevant parties and drive a resolution to address those in a timely manner
- Support key stakeholders in the writing of regulatory responses ensuring comprehensiveness and consistency across lines of business
- Manage escalations related to regulatory matters and/or deliverables, and provide support to ensure proper awareness and communication to applicable stakeholders including the regulators and Executive Management as applicable
- Ensure standards are maintained and followed related to the Bank’s regulatory interactions, including exam management, regulatory meeting, request for information and other ad hoc communications
- Drive and Execute quality reviews of all regulatory submissions to ensure deliverables meet strict deadlines and fulfil regulatory and quality standards; leverage knowledge of U.S. Banking regulations and compliance rules
- Oversee all facets of compliance-related regulatory exams, as well as additional exams covering other Independent Risk Management (IRM) functions, such as Operational Risk Management, etc., as requested by CRO; manage exam requests, meeting preparation and presentation, exam logistics, and communication of exam deadlines and updates to relevant parties, and Senior and Executive Management; and ensure efficient, effective and accurate communication between regulators and the Bank.
- Oversee the documentation and maintenance of comprehensive records of communications and regulatory affairs in line with both the Bank’s policies/standards and regulatory expectations
- Review minutes for regulatory meetings; consider internal stakeholder feedback; maintain RAO records of such
- Maintain and communicate the regulatory exam schedule, including exam results and documentation (SL) and key metrics related to RAO functions
- Establish and maintain RAO Procedure and relevant processes; facilitate procedure approvals and relevant training, as needed
- Periodically review and update the RAO Procedure, and conduct ad-hoc amendment per regulatory requirement or instruction from Management
- Develop and drive other regulatory affairs processes, as needed
- Oversee coordination and review of regulatory-related information and status updates for periodic reporting to Management and committees
- Review and assess items to be submitted for remediation validation and evaluation against stated regulatory expectations
- Review supporting documents for remediation to confirm regulatory MRAs/MRIAs are addressed
- Provide guidance and support in the development of remediation documentation and supporting information
- Monitor and track corrective actions regarding Regulatory Enforcement Action and MRA remediation plan progress; facilitate the preparation and reporting of overall remediation status of open issues to the management team; manage related communication with the regulators on ongoing and timely basis
- Organize and participate in internal meetings with stakeholders and management to discuss progress in corrective actions; and Report to Management with most updated information regarding regulatory affairs
- Other tasks or projects assigned by the Supervisor, including ad hoc regulatory updates or communications, as requested
- Bachelor’s degree required; advanced degree (i.e., MBA, JD, etc.) preferred.
- Minimum 10 years of work experience in banking, preferrably in a risk management and/or compliance-related function; prefer experience managing regulatory affairs, managing teams, and/or prior experience working at a regulatory agency. Or combination of 5 years exerience in banking and 5 years managing regulatory affairs, and/or prior experience at a regulatory agency. Understanding of bank processes, risks, controls, and overall governance framework.
- Experience in managing high-priority, cross-functional projects involving multiple stakeholders, and/or experience related to regulatory issue remediation a plus.
- Experience with committee and senior management-level reporting; development and review of policies/procedures.
- Strong knowledge of regulatory environment; knowledge of BSA/AML and Sanctions Compliance preferred.
- Excellent verbal and written communication skills
- Solid analytical and computer skills (Microsoft Office, with a focus on Excel/pivot tables) and detail-oriented.
- Strong relationship management/leadership skills; ability to work well under high-pressure situations and use negotiation/influencing skills to reach positive conclusions.
- Task oriented with sound time management skills; ability to manage and deliver against multiple priorities to meet critical deadlines.
- Strong team player mindset and effective collaborator.
- Sound problem-solving skills, able to drive solutions; possesses independent judgement and discernment.
- Strong knowledge of industry best practices, regulations, and industry developments.
- CAMS or other relevant certification preferred.
Actual salary is commensurate with candidate’s relevant years of experience, skillset, education and other qualifications.
: USD $110,000.00 - USD $230,000.00 /Yr.
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Find JobsSenior Level Regulatory Affairs Director Job Market
Who's Hiring
- Revolution Medicines25

- Insmed Incorporated5
- Azurity Pharmaceuticals4

- Abbott3
Top Industries Hiring
- Biotechnology & Pharmaceuticals99
- Medical Devices14
- Science & Research10
- Healthcare & Medical Services10
- Technology & Software8
Senior Level Regulatory Affairs Director Jobs: Frequently Asked Questions
How do I get a senior level regulatory affairs director job?
Employers at this level expect candidates who have owned regulatory strategy end-to-end, not just executed tasks. Demonstrating a history of leading submissions, managing agency relationships directly, and mentoring junior staff gives your application the strongest signal. Highlight cross-functional leadership, therapeutic area depth, and any experience navigating complex agency interactions such as pre-submission meetings or advisory committee preparation.
Which companies hire senior level regulatory affairs directors?
Companies hiring senior level regulatory affairs directors right now include Revolution Medicines, Revolution Medicines, and Insmed Incorporated, based on current listings on Migrate Mate as of June 2026. Hiring at this level comes primarily from large pharmaceutical and medical device manufacturers, established biotech firms, and contract research organizations that manage regulatory programs across multiple therapeutic areas or product lines.
Are there remote senior level regulatory affairs director jobs?
Yes, though availability varies by employer and therapeutic area. About 34% of senior level regulatory affairs director openings are remote or hybrid as of June 2026, reflecting how much of this work centers on documentation, strategy, and agency correspondence rather than on-site lab or manufacturing presence. Some roles with significant cross-functional or site-facing responsibilities remain on-site.
What makes a regulatory affairs director role senior level?
Senior level regulatory affairs director roles are defined by strategic ownership rather than execution support. Responsibilities typically include setting regulatory strategy for a product portfolio, leading agency interactions independently, overseeing submission teams, and mentoring regulatory affairs professionals at earlier career stages. The expectation shifts from completing assigned work to setting direction, resolving complex regulatory questions, and representing the function in cross-functional leadership discussions.
Which industries hire the most senior level regulatory affairs directors?
Senior Level regulatory affairs director roles concentrate in Biotechnology & Pharmaceuticals, Medical Devices, and Science & Research, based on current listings on Migrate Mate as of June 2026. These sectors drive hiring at this level because they operate under strict premarket approval, post-market surveillance, and quality system requirements that demand experienced regulatory leadership to manage product lifecycles and agency relationships.