Remote Clinical Operations Director Jobs
Remote clinical operations director jobs are open across the U.S. at remote-first biotech, pharma, and health tech companies running distributed clinical teams. Employers hiring remotely right now include Abco Maintenance, World Business Lenders, and Upstream USA. Scan the live roles below and apply to whichever ones fit.
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Director of Clinical Operations - Population Health RN
Vigilance Health
Remote | Full-Time
You've Done This Work Before. Now Do It At Scale.
You know what it takes to build, mobilize, and lead a remote care management team to excellence. You know what it takes to reach important industry metrics and compliance measures. You understand how to successfully engage and activate patients and how to coach your team of care managers to move the needle on patient health outcomes. You model and create a culture of mutual respect and collaboration. You've sat in rooms with FQHCs, IPAs, and payers and have spoken their language fluently.
Now imagine doing that with the full backing of an organization whose entire mission is built around the delivery of quality population care management — and where your work directly shapes the clinical programs that serve thousands of patients across diverse communities. That's what we're offering and you are who we’re looking for.
Who We Are
Vigilance Health partners with FQHCs, ACOs, IPAs, and payers to deliver Population Health and Care Management services that effect real change in people’s lives. We provide Chronic Care Management (CCM), Advanced Primary Care Management (APCM), Remote Patient Monitoring (RPM), and Behavioral Health Integration (BHI) programs — and we measure success the way our partners do: quality metrics, patient engagement, and improved health outcomes that show up in data.
Our purpose is simple, and we mean it: Change People's Lives — no matter their circumstances.
The Role
As our Clinical Operations Leader, you'll be the clinical engine behind our care management programs. This is a leadership role with real ownership — you'll build and coach the care management team, design and refine the clinical workflows they follow, and hold the clinical bar high across every service line we run.
You'll be working closely with our partners, most of whom are laser-focused on ACO quality measures and patient engagement. When they ask why HEDIS rates are moving or why patients aren't scheduling follow-ups, you'll be the one with answers — and a plan.
This role is remote, and you'll be leading a remote team, so your ability to build culture, accountability, and clinical consistency across distance is critical.
What You'll Own
Team Leadership
You'll recruit, onboard, coach, and develop a team of care managers. You set the standard for what great care management looks like and hold the team to it — with support, not just expectations.
Clinical Workflow Design
You'll build and continuously improve the clinical workflows that drive better outcomes. That means protocols that are practical, documented, and actually followed — not binders that collect dust.
ACO Quality & Patient Engagement Performance
Our partners live and die by their quality metrics. You'll monitor performance across ACO quality measures, identify where the gaps are, and lead the interventions that close them. Patient engagement is core to everything — including call answer rates, appointment scheduling rates, and no-show reduction. You'll understand why those numbers look the way they do and know what levers to pull.
Partner Collaboration
You'll be a trusted clinical voice for our partner sites — joining meetings, co-managing escalations, and making sure the clinical work we do is tightly aligned with what partners need to succeed with their payers and regulatory bodies.
Clinical Oversight Across Programs
Chronic Care Management, APCM, BHI, RPM — you'll ensure clinical standards, regulatory alignment, and documentation quality.
What Good Looks Like in 12 Months
-
Your care managers are hitting productivity targets and delivering high-quality, personalized care.
- ACO quality measure performance is trending up across partner panels.
Patient engagement rates — calls answered, appointments kept, reduction in no-
shows — are measurably improving.
- Clinical workflows are standardized, followed, and audit-ready.
- Partners view you as an extension of their clinical leadership team.
Leadership has clear, real-time visibility into performance, risk analysis, population analysis, and opportunity.
What You Bring
Experience That Matters Most
- Active RN license (BSN required; MSN a plus)
Experience working in or directly with FQHCs, ACOs, IPAs, or payers- Extensive familiarity with ACO quality measures (HEDIS, UDS, or equivalent)
Prior leadership of a remote care management program — you've managed remote
clinical staff and know how to build teamwork and accountability at a distance
5+ years of clinical experience, with meaningful time in population health or care
management
Nice to Have
- CCM, CPHQ, or population health certification
- Behavioral Health Integration (BHI) experience
- Experience launching or scaling new care management service lines
The Kind of Person Who Thrives Here
You're a self-starter and solution-focused. You can zoom out and think large-scale strategy and zoom in to, for example, coach a care manager on a specific patient interaction. You communicate clearly with clinical teams, operations leads, and external partners without losing anything in translation. When the data doesn't look right, you dig in.
Why Vigilance Health
-
Direct impact — your work shapes outcomes for real patients in real communities
- Leadership with latitude — we give you room to build programs the right way
- Mission-aligned partners — we work with organizations that care as much as we do
- Growth-oriented— we are scaling and adding partners who are driven by progress and excellence
- A team that has your back — we are collaborative and invested in each other's success
If you've been looking for a role where your population health expertise drives the clinical direction of a clinical team and an organization — this is it. We look forward to hearing from you.
Apply today. Let's change lives together.
Vigilance Health is an equal opportunity employer committed to building a diverse, inclusive team.
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Who's Hiring



Top Industries Hiring
- Consulting & Professional Services
What Employers Look For
The qualifications that appear most often in remote clinical operations director jobs.
- Bachelor's or advanced degree in life sciences, nursing, or a related clinical field
- Extensive experience managing Phase I through Phase IV clinical trials end to end
- Deep knowledge of ICH-GCP guidelines, FDA regulations, and applicable international standards
- Proven experience selecting, overseeing, and managing contract research organizations
- Proficiency with electronic data capture systems such as Medidata Rave or Veeva Vault
- Strong cross-functional leadership and budget management experience across global clinical programs
Tips for Your Remote Clinical Operations Director Job Search
Apply early to remote roles that fit
Migrate Mate lists remote clinical operations director openings from across the U.S. in one place. Search current roles by function and apply directly to the ones that match your background before postings close.
Document your async leadership style clearly
Remote employers want proof you can lead distributed clinical teams without daily face time. Call out specific tools you use, such as Veeva Vault, Medidata Rave, or structured weekly async updates, and show how your documentation kept trials on track.
Highlight cross-functional remote coordination experience
Remote clinical operations directors spend most of their day aligning CROs, site staff, data management, and regulatory teams across time zones. Name the cross-functional workflows you owned and how you kept stakeholders aligned without in-person meetings.
Prepare for competency-based remote interviews
Remote hiring panels for clinical operations directors focus on self-management and written decision-making under uncertainty. Prepare two or three structured examples of times you resolved a site issue or protocol deviation entirely through written communication and digital tools.
Remote Clinical Operations Director Jobs: Frequently Asked Questions
How do I get a remote clinical operations director job?
Remote clinical operations director roles go to candidates who can demonstrate they manage complex, multi-site trials without in-person oversight. Remote employers screen hard for async written communication, self-directed project management, and fluency with eClinical platforms like Medidata, Veeva, or Oracle. Showcasing distributed team leadership, clear documentation habits, and a history of hitting milestones without daily check-ins gives you a real edge over candidates without remote experience.
Which companies hire remote clinical operations directors?
Companies hiring remote clinical operations directors right now include Abco Maintenance, World Business Lenders, and Upstream USA, based on current remote listings on Migrate Mate as of November 2026. Remote-first biotech firms, contract research organizations with distributed site networks, and health tech platforms are the most consistent sources of these openings.
Can you get a remote clinical operations director job with no experience?
Yes, but remote entry-level director roles are harder to land because you'll be expected to operate independently from day one without office-based mentorship. Smaller remote-first biotech startups and CROs are more likely to consider candidates building toward director level. Demonstrating concrete trial management outcomes, strong async communication, and familiarity with electronic data capture systems can substitute for years of traditional experience.
Do you need a degree for remote clinical operations director jobs?
Usually, but the weight of your degree depends on what you pair it with. Most remote employers expect at least a bachelor's in a life sciences or health-related field, and many prefer a master's or equivalent. What moves your application forward remotely is demonstrated results: trials completed on time, teams managed across time zones, and regulatory submissions you can point to directly.
Which industries hire the most remote clinical operations directors?
Remote clinical operations director roles concentrate in Consulting & Professional Services, based on current remote listings on Migrate Mate as of November 2026. These sectors hire remotely because their clinical programs run across distributed investigator sites, making a centralized physical presence less critical than strong digital oversight and coordination.
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