Remote Director of Commercial Operations Jobs
Remote Director of Commercial Operations jobs are open across the U.S. at remote-first firms and distributed teams in sectors like SaaS, fintech, healthcare technology, and professional services. Companies hiring remote director of commercial operations talent right now include Karius, Vera Therapeutics, and Siemens Healthineers. Scan the live roles below and apply to whichever ones fit.
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Job Title: Director, Commercial Strategy & Operations (Ophthalmology)
Location: Remote in US & UK
- Over 2,500 sites certified worldwide, since 1995
- Phase I through post-marketing experience across anterior segment and retina trials
- Clinical Ophthalmology, Optometry, and clinical trial expertise
Primary Purpose
The Director, Commercial Strategy & Operations shapes and supports OptymEdge’s commercial growth strategy while leading a disciplined, data-driven commercial operations function. The role is accountable for commercial intelligence, qualified pipeline generation, CRM and forecasting governance, and effective proposal, budget and pricing processes. It combines strategic thinking with hands-on leadership to improve commercial performance and enable sustainable new business growth.
The primary focus:
- Commercial strategy and growth plan
- Data-driven commercial operations
- Qualified pipeline and new business growth
- Pricing and contract governance
- Alignment between lead generation and the commercial teams
- Team performance and development
Responsibilities:
- Work with the Head of Commercial to develop annual commercial plans, target segments, priority accounts and growth initiatives.
- Analyse market trends, clinical development pipelines, customer needs and competitor activity to identify attractive opportunities and inform positioning.
- Provide practical recommendations to leadership on pipeline quality, customer opportunities, pricing trends and commercial priorities.
- Support account planning, qualification and win strategy for high-priority pursuits.
- Lead commercial operations including Salesforce governance, pipeline reporting, forecast processes, performance dashboards and KPI definitions.
- Own the governance and continuous improvement of proposal, budget and pricing workflows, ensuring timely, accurate outputs and appropriate approvals.
- Develop clear commercial controls for pricing, discounts and non-standard terms in partnership with appropriate decision-makers.
- Improve data quality, reporting consistency, win/loss analysis and adoption of effective commercial tools and processes.
- Lead and develop lead generation capability, setting measurable expectations for qualified meetings, accepted opportunities and pipeline contribution.
- Define target account priorities and research-led prospecting approaches to create a reliable flow of relevant opportunities.
- Engage prospective customers directly where senior-level involvement can improve access or accelerate qualification.
- Establish practical qualification criteria, lead follow-up expectations and conversion feedback loops to improve the quality of pipeline generated.
- Partner with commercial leadership to align prospecting priorities with sales capacity, customer strategy and opportunity conversion needs.
- Coordinate with relevant marketing and enterprise stakeholders on campaigns, conferences and market engagement, while respecting their functional ownership.
- Facilitate efficient collaboration across finance, scientific, operational and other teams to support commercial decision-making and timely execution.
- Coach and develop assigned team members, establish clear deliverables and foster accountability for results.
- Monitor commercial process effectiveness and recommend improvements to turnaround times, governance, reporting and productivity.
- Promote a proactive, analytical and growth-focused commercial culture across the organisation.
Additional duties, as assigned.
- Demonstrated capability in new-logo pipeline generation, prospecting strategy and development of customer relationships.
- Strong Salesforce, forecasting, commercial analytics, pricing governance and process improvement experience.
- Experience in pharmaceutical, biotechnology, CRO, clinical trials or broader life sciences preferred.
- Experience building or leading a small team and influencing across a global organisation.
- Excellent commercial judgement, analytical, communication and presentation skills; ophthalmology or endpoint services experience advantageous.
Why work at Emmes?
At Emmes, your actions and hard work will have a direct impact on public health initiatives, both globally and in our local communities with opportunities for volunteerism through our Emmes Cares community engagement program. We offer a competitive benefits package focused on the health and needs of our growing workforce, including:
Flexible Approved Time Off
Tuition Reimbursement
401k Retirement Plan
Work From Home Anywhere in the US
Maternal/Paternal Leave
Casual Dress Code & Work Environment
CONNECT WITH US!
The Emmes Company, LLC is an equal opportunity employer and does not discriminate in its selection and employment practices. All qualified applicants will receive consideration for employment without regard to disability or protected veteran status.
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Who's Hiring



What Employers Look For
The qualifications that appear most often in remote director of commercial operations jobs.
- 7 or more years of experience in commercial operations, revenue operations, or sales operations
- Demonstrated ability to build and optimize quote-to-cash or order-to-cash processes
- Proficiency with CRM platforms and CPQ or pricing tools at an administrative or configuration level
- Experience partnering with sales, finance, and legal on contract structure and deal approval workflows
- Strong data analysis skills with the ability to build commercial forecasts and performance dashboards
- Bachelor's degree in business, finance, or a related field, with an MBA preferred for senior roles
Tips for Your Remote Director of Commercial Operations Job Search
Apply early to remote roles that fit
Migrate Mate lists remote director of commercial operations openings from across the U.S. in one place. Search roles by function and apply directly to the ones that match your background before competition builds up in the first week.
Demonstrate async leadership in your materials
Remote employers hiring at the director level look for evidence you can run commercial operations without in-person check-ins. Use your resume and cover letter to show how you have managed distributed teams, run pipeline reviews in writing, and kept cross-functional stakeholders aligned through documentation.
Highlight remote-ready tools you use daily
Name the specific platforms you work in, such as Salesforce, HubSpot, Clari, Notion, or Slack, and describe how you used them to drive commercial outcomes. Remote hiring managers in this role want to see you already operate in a distributed tech stack, not that you are willing to learn one.
Prepare for async-first remote interviews
Many remote-first companies run initial interview stages over written assessments or recorded video responses before scheduling live calls. Practice articulating your commercial strategy and cross-functional decision-making process clearly and concisely in writing, since that skill signals exactly how you will perform in the role.
Remote Director of Commercial Operations Jobs: Frequently Asked Questions
How do I get a remote director of commercial operations job?
Target remote-first companies and distributed-team organizations where commercial operations leadership is built around async collaboration rather than in-person oversight. Remote employers in this role screen heavily for self-direction, strong written communication, and demonstrated experience managing cross-functional revenue processes without close supervision. Showing proficiency with tools like CRMs, revenue intelligence platforms, and project management software gives candidates a clear edge.
Which companies hire remote director of commercial operationss?
Companies hiring remote director of commercial operationss right now include Karius, Vera Therapeutics, and Siemens Healthineers, based on current remote listings on Migrate Mate as of November 2026. Remote-first SaaS firms, distributed fintech teams, and growth-stage healthcare technology companies account for a large share of these openings, since their commercial operations functions are designed from the ground up to run across time zones.
Can you get a remote director of commercial operations job with no experience?
Yes, but remote director-level roles require demonstrated independence, so entry paths are narrower than on-site equivalents. Remote-first startups and early-stage companies occasionally hire candidates who can show strong commercial operations results from previous roles, freelance projects, or revenue operations consulting work. Quantified outcomes, clear process documentation skills, and familiarity with async communication tools open doors when a formal title is missing.
Do you need a degree for remote director of commercial operations jobs?
Not always. Remote employers in this field weigh demonstrated commercial operations results, revenue growth outcomes, and cross-functional leadership experience alongside or instead of formal credentials. Candidates who can show they have built and managed commercial processes, improved pipeline efficiency, or led distributed sales operations teams often move forward regardless of their educational background.
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