Remote Lead UI/UX Designer Jobs
Remote Lead UI/UX Designer jobs are in strong demand across the U.S., with remote-first companies and distributed product teams actively hiring designers who can lead end-to-end experience work without being in an office. Employers hiring remotely right now include VML, Uvation, and DentalChat. Scan the live roles below and apply to whichever ones fit.
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See related jobsMayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
The UI/UX Designer (User Interface/User Experience Designer) plays a key multidisciplinary role in the design process across immersive learning experiences for Mayo Clinic College of Medicine & Science. The role teams up with UX researchers to deeply understand the user experience of our different audiences and shape unique visual approaches through iterative prototype testing. They have an understanding of learning science basics, instructional design, as well as medical and simulation-based education. They partner with educators, clinical subject matter experts, simulation staff, 3D artists, medical illustrators, animators, XR engineers and other content specialists to design immersive and XR applications, such as simulations with AI-driven virtual patients, interactive 3D anatomy experiences, and patient-focused learning apps, with a focus on usability, trust, and clinical accuracy. They also iterate on the design of these applications and collaborate with developers to revise them to updated specifications. Primary responsibilities include: Contributing to all stages of the design process, including wireframing layouts, designing mockups at multiple screen sizes, and designing and refining conversational AI interactions. They represent users in the design of user interfaces that reflect best practices for different device types and accessibility. They participate in the user experience research process to establish design solutions that meet user needs and goals. They incorporate UX findings and brand identity into design patterns that are not only visually appealing but also enrich the user experience. The UI/UX Designer collaborates closely with other team members and stakeholders to improve navigation schemes, interaction patterns, and digital storytelling. They building familiarity with a learning management system and work closely with content contributors to create engaging immersive experiences. They develop and adapt design specifications for developers, taking into account feasibility and performance constraints. They engage in spatial interaction design, UX design for comfort and motion sickness, interaction methods (hands, controllers, gaze, voice), and XR accessibility. The ideal candidate will: Develop a deep understanding and empathy for the experience of our current and prospective learners. Be a voracious consumer of design across multiple industries and modalities, with particular focus on contemporary practices and peer institutions in higher education and academic medicine.
Advocate for an inclusive, accessible, user centered approach to each and every product. The UI/UX Designer will communicate persuasively to stakeholders about design decisions and how they serve business objectives They will have excellent relationship management skills, emotional intelligence, and the desire to work with a close-knit team to deliver high-quality products in a timely fashion.
This position will require on-site presence with the flexibility to work from home as needed throughout the week once oriented to the role.
This position is a combination of remote and on-site work; individual must live within a 100 mile driving distance to the Rochester Mayo Clinic campus.
**Visa sponsorship is not available for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
Qualifications
Bachelor’s degree in UI/UX design, Interaction Design, Human-Computer Interaction (HCI), Graphic design, Multimedia Arts, or a related field. At least of 5 years of experience producing user interface design with demonstrated impact is strongly recommended. Must demonstrate expert skills in UI design methods (prototyping, interaction flow diagrams, wireframes, and interface specifications) and strong visual design acumen. Experience in, or a willingness to learn, design for XR/AR/VR, 360 Video, 3D software and game engines (Unity, Unreal, etc.) is preferred. Platforms will include web, mobile, desktop, headsets and other wearables. Experience designing AI interactions is preferred. Must demonstrate up-to-date knowledge of modern digital and interaction design principles and trends, with the ability to clearly articulate complex design problems and solutions using strong communication and presentation skills. Experience in learning design and a portfolio demonstrating deliverables throughout the design process for products/websites is recommended. Health care or higher education experience is a plus. Experience with: Using user interface design software such as Sketch, Figma, or Adobe XD; HTML, CSS, and the basics of front-end web development; Addressing accessibility concerns for digital products, including optimizing for assistive technologies.
Additional Qualifications
- Experience in educational technology, healthcare, or simulation-based design is highly valued.
- Knowledge of WCAG Accessibility Standards is required.
- Portfolio demonstrating a range of immersive projects, ideally with cross-platform applications or AI-enhanced designs.
Responsibilities:
Apply user-centered design process to continuously improve and innovate Mayo Clinic websites, applications, products, and services.
Create conceptual models, wireframes, and interactive prototypes to test design concepts for usability and/or communicate ideas to stakeholders.
Apply understanding of user needs to define navigation and interaction systems, including site structures, navigation flows, user interfaces, and hierarchies that are engaging and intuitive.
Design user interface solutions that are accessible, inclusive, and device-appropriate.
Proactively communicate status updates to relevant stakeholders throughout the design process.
Communicate persuasively to stakeholders about design decisions and how they serve both user and business objectives.
Implement Mayo Clinic visual identity assets in a variety of different environments.
Leverage the institutional design system appropriately to ensure that interfaces align with the visual identity as closely as possible while serving the needs of users.
Work with HTML, CSS, and content management systems to implement the brand identity across internal and external websites.
Deliver visual designs and relevant interface specifications that effectively inform UI engineering colleagues.
Effectively collaborate with content publishing and UI engineering colleagues throughout development to ensure design vision is accurately translated from design documentation to the final product.
Evangelize user-centered design practices and standards.
Proactively seek to incorporate UX design best practices and user research insights into all digital interfaces.
Review final designs to ensure that standards and guidelines have been followed consistently, thoroughly, and correctly.
Mentor and educate content publishing team members in user-centered design philosophy and research insights.
Champion the user's needs and help others maintain focus on them.
Contribute to continuous improvements in user experience.
Participate in user testing, research-related testing, and feedback review sessions.
Stay up to date with best practices in user experience and the latest audience specific UX insights.
Stay current with evolving digital standards and technologies and learn new skills as needed.
Develop deep understanding and empathy for the experience of our current and prospective learners.
Exemption Status
Exempt
Compensation Detail
$85,467.20- $128,252.80 / year
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Monday - Friday 8:00 am - 5:00 pm This position is a combination of remote and on-site work; individual must live within driving distance to the Rochester Mayo Clinic campus.
Weekend Schedule
As needed (Infrequent)
International Assignment
No
Site Description
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
Pam Sivly
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
The UI/UX Designer (User Interface/User Experience Designer) plays a key multidisciplinary role in the design process across immersive learning experiences for Mayo Clinic College of Medicine & Science. The role teams up with UX researchers to deeply understand the user experience of our different audiences and shape unique visual approaches through iterative prototype testing. They have an understanding of learning science basics, instructional design, as well as medical and simulation-based education. They partner with educators, clinical subject matter experts, simulation staff, 3D artists, medical illustrators, animators, XR engineers and other content specialists to design immersive and XR applications, such as simulations with AI-driven virtual patients, interactive 3D anatomy experiences, and patient-focused learning apps, with a focus on usability, trust, and clinical accuracy. They also iterate on the design of these applications and collaborate with developers to revise them to updated specifications. Primary responsibilities include: Contributing to all stages of the design process, including wireframing layouts, designing mockups at multiple screen sizes, and designing and refining conversational AI interactions. They represent users in the design of user interfaces that reflect best practices for different device types and accessibility. They participate in the user experience research process to establish design solutions that meet user needs and goals. They incorporate UX findings and brand identity into design patterns that are not only visually appealing but also enrich the user experience. The UI/UX Designer collaborates closely with other team members and stakeholders to improve navigation schemes, interaction patterns, and digital storytelling. They building familiarity with a learning management system and work closely with content contributors to create engaging immersive experiences. They develop and adapt design specifications for developers, taking into account feasibility and performance constraints. They engage in spatial interaction design, UX design for comfort and motion sickness, interaction methods (hands, controllers, gaze, voice), and XR accessibility. The ideal candidate will: Develop a deep understanding and empathy for the experience of our current and prospective learners. Be a voracious consumer of design across multiple industries and modalities, with particular focus on contemporary practices and peer institutions in higher education and academic medicine.
Advocate for an inclusive, accessible, user centered approach to each and every product. The UI/UX Designer will communicate persuasively to stakeholders about design decisions and how they serve business objectives They will have excellent relationship management skills, emotional intelligence, and the desire to work with a close-knit team to deliver high-quality products in a timely fashion.
This position will require on-site presence with the flexibility to work from home as needed throughout the week once oriented to the role.
This position is a combination of remote and on-site work; individual must live within a 100 mile driving distance to the Rochester Mayo Clinic campus.
**Visa sponsorship is not available for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
Qualifications
Bachelor’s degree in UI/UX design, Interaction Design, Human-Computer Interaction (HCI), Graphic design, Multimedia Arts, or a related field. At least of 5 years of experience producing user interface design with demonstrated impact is strongly recommended. Must demonstrate expert skills in UI design methods (prototyping, interaction flow diagrams, wireframes, and interface specifications) and strong visual design acumen. Experience in, or a willingness to learn, design for XR/AR/VR, 360 Video, 3D software and game engines (Unity, Unreal, etc.) is preferred. Platforms will include web, mobile, desktop, headsets and other wearables. Experience designing AI interactions is preferred. Must demonstrate up-to-date knowledge of modern digital and interaction design principles and trends, with the ability to clearly articulate complex design problems and solutions using strong communication and presentation skills. Experience in learning design and a portfolio demonstrating deliverables throughout the design process for products/websites is recommended. Health care or higher education experience is a plus. Experience with: Using user interface design software such as Sketch, Figma, or Adobe XD; HTML, CSS, and the basics of front-end web development; Addressing accessibility concerns for digital products, including optimizing for assistive technologies.
Additional Qualifications
- Experience in educational technology, healthcare, or simulation-based design is highly valued.
- Knowledge of WCAG Accessibility Standards is required.
- Portfolio demonstrating a range of immersive projects, ideally with cross-platform applications or AI-enhanced designs.
Responsibilities:
Apply user-centered design process to continuously improve and innovate Mayo Clinic websites, applications, products, and services.
Create conceptual models, wireframes, and interactive prototypes to test design concepts for usability and/or communicate ideas to stakeholders.
Apply understanding of user needs to define navigation and interaction systems, including site structures, navigation flows, user interfaces, and hierarchies that are engaging and intuitive.
Design user interface solutions that are accessible, inclusive, and device-appropriate.
Proactively communicate status updates to relevant stakeholders throughout the design process.
Communicate persuasively to stakeholders about design decisions and how they serve both user and business objectives.
Implement Mayo Clinic visual identity assets in a variety of different environments.
Leverage the institutional design system appropriately to ensure that interfaces align with the visual identity as closely as possible while serving the needs of users.
Work with HTML, CSS, and content management systems to implement the brand identity across internal and external websites.
Deliver visual designs and relevant interface specifications that effectively inform UI engineering colleagues.
Effectively collaborate with content publishing and UI engineering colleagues throughout development to ensure design vision is accurately translated from design documentation to the final product.
Evangelize user-centered design practices and standards.
Proactively seek to incorporate UX design best practices and user research insights into all digital interfaces.
Review final designs to ensure that standards and guidelines have been followed consistently, thoroughly, and correctly.
Mentor and educate content publishing team members in user-centered design philosophy and research insights.
Champion the user's needs and help others maintain focus on them.
Contribute to continuous improvements in user experience.
Participate in user testing, research-related testing, and feedback review sessions.
Stay up to date with best practices in user experience and the latest audience specific UX insights.
Stay current with evolving digital standards and technologies and learn new skills as needed.
Develop deep understanding and empathy for the experience of our current and prospective learners.
Exemption Status
Exempt
Compensation Detail
$85,467.20- $128,252.80 / year
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Monday - Friday 8:00 am - 5:00 pm This position is a combination of remote and on-site work; individual must live within driving distance to the Rochester Mayo Clinic campus.
Weekend Schedule
As needed (Infrequent)
International Assignment
No
Site Description
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
Pam Sivly
See All 5 Remote Lead UI/UX Designer Jobs
Find roles that match your experience and apply in just a few clicks.
Find JobsRemote Lead UI/UX Designer Job Market
Who's Hiring
Top Industries Hiring
- Consulting & Professional Services
What Employers Look For
The qualifications that appear most often in remote lead UI/UX designer jobs.
- Five or more years of UX or product design experience, including at least one lead or senior role
- Expert proficiency in Figma, including components, auto layout, and shared design systems
- Demonstrated experience leading end-to-end design projects from discovery through launch
- Ability to mentor junior and mid-level designers and provide structured critique
- Experience collaborating directly with product managers and engineers in agile workflows
- Portfolio showing complex, multi-platform UX work with documented process and measurable outcomes
Tips for Your Remote Lead UI/UX Designer Job Search
Show async collaboration in your portfolio
Remote design leaders are expected to move work forward without real-time check-ins. Add case studies that explain how you gathered feedback asynchronously, ran remote design critiques in Figma or Miro, and kept stakeholders aligned across time zones.
Apply early to remote roles that fit
Migrate Mate lists remote lead ui/ux designer openings from across the U.S. in one place, so you can find roles that match your experience and apply directly. Getting your application in early increases your visibility before a role draws a large applicant pool.
Demonstrate written communication as a design skill
Remote hiring managers read your writing before they see your face. Craft application materials that explain your design decisions clearly and concisely. A well-written project summary or design brief excerpt signals you can align distributed teams without relying on in-person walkthroughs.
Highlight cross-functional remote leadership experience
Remote lead roles require you to influence engineers, product managers, and stakeholders you may never meet in person. Call out specific examples of leading design reviews, running workshops in Miro or FigJam, and documenting design systems or decision logs that distributed teams rely on.
Remote Lead UI/UX Designer Jobs: Frequently Asked Questions
How do I get a remote lead ui/ux designer job?
Target remote-first SaaS companies, fintech startups, and distributed product teams, since these organizations are most likely to hire lead ui/ux designers remotely. Remote employers screen heavily for self-direction, strong written communication, and the ability to align stakeholders asynchronously. A portfolio that shows end-to-end design ownership, decision rationale, and cross-functional collaboration gives you a clear edge over candidates who only show polished final screens.
Which companies hire remote lead ui/ux designers?
Remote lead ui/ux designer roles are posted by VML, Uvation, and DentalChat and others right now, based on current remote listings on Migrate Mate as of November 2026. These tend to be remote-first software companies, distributed fintech and healthtech teams, and enterprise SaaS organizations that run product design across multiple time zones.
Can you get a remote lead ui/ux designer job with no experience?
Yes, but remote lead roles are harder to land without experience because you're expected to operate independently and guide other designers from day one. Entry paths include contract or freelance remote projects that demonstrate leadership, contributing to open-source or nonprofit design work, and targeting early-stage startups where you can own the design function. A strong case study showing how you led a design decision, not just executed one, matters more than a formal title.
Do you need a degree for remote lead ui/ux designer jobs?
Not always. Many remote employers care far more about your portfolio, your ability to communicate design rationale in writing, and your history of leading design work than your educational credentials. A degree in interaction design, human-computer interaction, or a related field can help in more traditional organizations, but bootcamp graduates and self-taught designers regularly land remote lead roles by showing real, documented outcomes.
Which industries hire the most remote lead ui/ux designers?
Remote lead ui/ux designer roles concentrate in Consulting & Professional Services, based on current remote listings on Migrate Mate as of November 2026. These sectors rely on distributed product teams that need experienced designers who can lead experience strategy and ship work without being physically co-located.
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Find roles that match your experience and apply in just a few clicks.
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