Senior Clinical Project Manager Jobs in North Carolina

Senior Clinical Project Manager jobs in North Carolina are in strong and consistent demand, driven by the state's deep concentration of pharmaceutical manufacturers, contract research organizations, and academic medical centers serving clinical trials from early-phase through post-market. The heaviest hiring is in the Research Triangle (Raleigh-Durham-Chapel Hill), Charlotte, and Greensboro, where employers such as Syneos Health, Labcorp Drug Development, and Duke University Health System maintain substantial clinical operations. Oncology trials, rare disease studies, and regulatory submissions management are the most sought-after specialties. Find a role that fits below and apply directly.

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Overview

Open roles6
Top employerIQVIA
Top cityDurham, NC
Cities hiring5
Work type40% Remote
Top industryHealthcare

Showing 5 of 6+ Senior Clinical Project Manager jobs

Mgr II GBD Special Programs-1915i/IDD Clinical Care Advisor Team
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Added 4d ago
Mgr II GBD Special Programs-1915i/IDD Clinical Care Advisor Team
Elevance Health
Winston-Salem, North Carolina
Business Development
Customer Success
Partnerships & Business Development
Project Management
Master's degree in social work
10,000+

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Sr. Clinical Project Manager, IQVIA Biotech
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Added 2w ago
Sr. Clinical Project Manager, IQVIA Biotech
IQVIA
Durham, North Carolina
Account Management
Business Development
Customer Success
$93k - $233k/yr
Remote (US)
Bachelor's degree
10,000+

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(Senior) Clinical Project Manager, IQVIA Biotech
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Added 1mo ago
(Senior) Clinical Project Manager, IQVIA Biotech
IQVIA
Durham, North Carolina
Business Development
Business Operations
Executive Leadership & C-Suite
$68k - $233k/yr
Remote (US)
Bachelor's degree
10,000+

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Clinical Project Manager II / Senior Clinical Project Manager
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Added 1mo ago
Clinical Project Manager II / Senior Clinical Project Manager
United Therapeutics
Research Triangle Park, North Carolina
Biotech & Life Sciences
Clinical Trials & Medical Research
Research & Academia
Hybrid
Master's degree
1,001-5,000

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Senior Clinical Project Manager
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Added 3mo ago
Senior Clinical Project Manager
Azurity Pharmaceuticals - US
Raleigh, North Carolina
Business Analysis
Compliance & Risk
Consulting & Professional Services
Hybrid
Bachelor's degree

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See All 6 Senior Clinical Project Manager Jobs in North Carolina

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Senior Clinical Project Manager Jobs by City in North Carolina

Where North Carolina roles are concentrated, by current openings.

Durham
2 jobs
Raleigh
1 job
Morehead City
1 job
Winston-Salem
1 job
Research Triangle Park
1 job

Senior Clinical Project Manager Job Market in North Carolina

A snapshot from current North Carolina openings, updated as new roles post.

Who's Hiring

IQVIA2 open roles
Elevance Health1 open role
United Therapeutics1 open role

Top Industries Hiring

  • Healthcare & Medical Services

What North Carolina Employers Look For

The qualifications that appear most often in senior clinical project manager jobs across North Carolina.

  • Bachelor's or advanced degree in life sciences, nursing, or a related clinical field
  • PMP or CAPM certification preferred by most North Carolina clinical employers
  • Minimum five years of clinical trial management experience under ICH-GCP guidelines
  • Proficiency with clinical trial management systems such as Veeva Vault or Oracle Siebel
  • Demonstrated ability to manage cross-functional teams across multiple concurrent studies
  • Strong working knowledge of FDA regulations and IND/NDA submission processes

Senior Clinical Project Manager Jobs in North Carolina: Frequently Asked Questions

How do you become a senior clinical project manager in North Carolina?

The typical path starts with a bachelor's degree in a life science, nursing, or health-related field, followed by several years of hands-on clinical trial coordination or monitoring experience. North Carolina does not require a state-issued license specific to clinical project management, but the Project Management Professional certification and ACRP or SOCRA clinical research credentials are widely expected by Research Triangle and Charlotte employers. Advancing from a CRA or CRC role at a local CRO or academic medical center is the most common route.

How much do senior clinical project managers make in North Carolina?

Senior clinical project managers in North Carolina earn a median of about $100,820 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $61,570 for the lowest 10% to over $164,050 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior clinical project managers in North Carolina?

Employers hiring senior clinical project managers in North Carolina right now include IQVIA, Elevance Health, and United Therapeutics, based on current listings on Migrate Mate as of November 2026. North Carolina's dense cluster of CROs and biopharma companies in the Research Triangle Park area makes it one of the most active hiring markets for this role in the Southeast.

Which North Carolina cities have the most senior clinical project manager jobs?

The cities with the most senior clinical project manager openings in North Carolina are Durham, Raleigh, and Morehead City. The Research Triangle anchors most of this demand because Research Triangle Park hosts the North American headquarters of multiple global CROs and biopharma companies, while Charlotte's growing life sciences corridor and academic medical campuses in Greensboro and Winston-Salem contribute a steady share of postings.

Are there remote senior clinical project manager jobs in North Carolina?

Yes, and more than most clinical roles, because senior clinical project managers spend much of their time on planning, vendor oversight, and documentation rather than direct site visits. About 80% of senior clinical project manager openings tied to North Carolina are remote or hybrid as of November 2026, reflecting the desk-heavy nature of senior-level trial oversight. Site initiation and monitoring visit responsibilities are the portions most likely to require in-person presence.

How can I get hired as a senior clinical project manager in North Carolina with little or no experience?

The most realistic entry point is a clinical research coordinator or CRA I role at one of the Research Triangle's large CROs, such as Syneos Health or Labcorp Drug Development, both of which run structured associate CRA programs for candidates without prior industry experience. A SOCRA or ACRP entry-level certification strengthens an application considerably. Candidates with nursing backgrounds or lab research experience from institutions like Duke, UNC-Chapel Hill, or Wake Forest can often move laterally into trial coordination before progressing toward project management.

Where can I find and apply to senior clinical project manager jobs in North Carolina?

You can find and apply to senior clinical project manager jobs in North Carolina directly on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the available roles, identify the ones that match your experience and preferred location or work arrangement, and apply directly to each position that fits.

See All 6 Senior Clinical Project Manager Jobs in North Carolina

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