Senior Clinical Trial Manager Jobs in Denver, CO
Senior Clinical Trial Manager jobs in Denver are in active demand, concentrated in the Denver Tech Center, RiNo, and Fitzsimons life sciences corridor across biopharmaceutical, contract research, and medical device sectors. Employers hiring right now include Medpace. Scan the live roles below and apply to whichever ones fit.
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This is a fantastic opportunity for recent PhD graduates to enter the industry, receive solid foundational training, work in an international environment, and develop their career in the research and development of cutting-edge therapeutics. Candidates should expect to have an intensive training period and show the desire and aptitude for an accelerated career path into Clinical Trial Management (CTM).
- Communicate and collaborate on global study activities; working closely with the project coordinator and clinical trial manager;
- Ensure timely delivery of recurrent tasks consistently with a high degree of accuracy;
- Compile and maintain project-specific status reports within the clinical trial management system;
- Interact with the internal project team, Sponsor, study sites, and third-party vendors;
- Provide oversight and quality control of our internal regulatory filing system;
- Provide oversight and management of study supplies;
- Create and maintain project timelines; and
- Coordinate project meetings and produce quality minutes.
- PhD in Life Sciences;
- Expertise related to obesity, diabetes, MASH, MAFLD, hypoglycemia, or rare endocrine and metabolic diseases
- Fluency in English with solid presentation skills;
- Ability to work in a fast-paced dynamic industry within an international team;
- Prior experience within the CRO or pharmaceutical industry not required but will be advantageous; and
- Excellent computer (word-processing, databases, Excel, Windows), organizational, and communication skills.
Compensation
The work we’ve done over the past 30+ years has positively impacted the lives of countless patients and families who face hundreds of diseases across all key therapeutic areas. The work we do today will improve the lives of people living with illness and disease in the future.
Awards
- Named a Top Workplace in 2024 by The Cincinnati Enquirer
- Recognized by Forbes as one of America's Most Successful Midsize Companies in 2021, 2022, 2023 and 2024
- Continually recognized with CRO Leadership Awards from Life Science Leader magazine based on expertise, quality, capabilities, reliability, and compatibility
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Who's Hiring

Top Industries Hiring
- Healthcare & Medical Services21
- Biotechnology & Pharmaceuticals21
- Science & Research17
Senior Clinical Trial Manager Jobs in Denver: Frequently Asked Questions
How do I get a senior clinical trial manager job in Denver?
Targeting Denver's Fitzsimons Innovation Campus and the biopharmaceutical clusters in the Denver Tech Center gives you the strongest starting point. Contract research organizations and mid-size biotech firms in the area hire most actively for this role. Candidates who bring Phase II or Phase III oncology or rare disease trial experience and familiarity with FDA regulatory submissions consistently stand out in Denver's competitive market.
Which companies hire senior clinical trial managers in Denver?
Companies currently hiring senior clinical trial managers in Denver include Medpace, per current listings on Migrate Mate as of July 2026. Denver's hiring mix leans toward contract research organizations, specialty biopharmaceutical companies, and academic medical center affiliates operating out of the Fitzsimons and Denver Tech Center areas.
Are there remote senior clinical trial manager jobs in Denver?
Yes, though partially: senior clinical trial manager work is hybrid by nature, with site oversight and sponsor meetings requiring in-person presence while protocol management and data review are often done remotely. About 43% of senior clinical trial manager openings tied to Denver are remote or hybrid as of July 2026, with CRO-affiliated roles offering the most schedule flexibility. Sponsor-side positions at Denver-based biotechs tend to require more on-site presence.
How can I get a senior clinical trial manager job in Denver with little or no experience?
The most realistic entry path in Denver is moving up through a clinical research associate or study coordinator role at one of the city's contract research organizations or at UCHealth and Children's Hospital Colorado, both of which run active trial programs. Building experience on Phase I or early-phase oncology studies at Fitzsimons-area institutions helps, and earning a CCRP credential signals readiness for senior responsibilities to local hiring managers.
Which industries hire the most senior clinical trial managers in Denver?
Most senior clinical trial manager openings in Denver sit in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Science & Research, per current listings on Migrate Mate as of July 2026. Denver's established life sciences ecosystem, anchored by the Fitzsimons Innovation Campus and a growing cluster of oncology and rare disease biotechs, drives consistent demand for senior trial oversight professionals across those sectors.
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