STEM OPT Clinical Informatics Specialist Jobs
Clinical Informatics Specialist roles sit at the intersection of healthcare and technology, making them strong matches for STEM OPT graduates in health informatics, biomedical engineering, or computer science. Your 24-month STEM OPT extension applies here, giving you up to 36 months total, provided your employer is enrolled in E-Verify.
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Get Access To All JobsINTRODUCTION
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.
ROLE AND RESPONSIBILITIES
As a Lilly Research Informatics Platform Engineer, you will build cutting edge AI & Informatics tools with a team of passionate engineers to accelerate & enhance Lilly’s drug discovery process. You will be hands-on designing architecture, deploying scalable services/integrations, and developing novel software to harness the power of ML & computational tooling to assist researchers in their day-to-day work. You will collaborate closely with partners from Lilly Research Labs, AI, Software Engineering, and industry leading partners outside Lilly to accelerate medicine discovery for Lilly.
How You'll Succeed
- Design, architect and develop robust, scalable and secure software solutions with a hands-on approach.
- Collaborate within a team of engineers, using best practices in software development such as design review, code reviews, testing, and continuous integration/continuous deployment (CI/CD).
- Build and maintain microservices architectures and APIs, ensuring seamless interoperability and data flow across platforms.
- Implement containerization solutions, particularly using Kubernetes, to support deployment and scaling needs.
- Collaborate with diverse technical teams, including R&D, Data Science, IT Operations, and AI/ML teams, to translate business requirements into technical solutions.
- Ensure optimal system performance, reliability, and security through proactive monitoring, automated testing, and continuous improvement.
- Troubleshoot complex technical issues in a complex microservice architecture, collaborating across teams to identify, resolve, and build future mitigation strategies.
- Monitor and track operational metrics.
- Ensure robust integration of AI/ML models into production environments, focusing on scalability, performance, and reliability.
BASIC QUALIFICATIONS
- Bachelor's degree in Computer Science, Information Technology, Software Engineering.
- Minimum 4 years of experience in architecture and software engineering.
PREFERRED QUALIFICATIONS
- Master's degree in Computer Science, Information Technology, Software Engineering.
- Proven track record of delivering complex, cross-functional IT solutions.
LOCATION & WORK FLEXIBILITY
This role is based at our Corporate Center in Indianapolis. We offer a flexible hybrid work model, with three days onsite and two days working remotely each week, supporting both collaboration and work-life balance.
- Remote employees will be considered for those not based near Indianapolis, IN.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $132,000 - $244,200.
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
INTRODUCTION
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.
ROLE AND RESPONSIBILITIES
As a Lilly Research Informatics Platform Engineer, you will build cutting edge AI & Informatics tools with a team of passionate engineers to accelerate & enhance Lilly’s drug discovery process. You will be hands-on designing architecture, deploying scalable services/integrations, and developing novel software to harness the power of ML & computational tooling to assist researchers in their day-to-day work. You will collaborate closely with partners from Lilly Research Labs, AI, Software Engineering, and industry leading partners outside Lilly to accelerate medicine discovery for Lilly.
How You'll Succeed
- Design, architect and develop robust, scalable and secure software solutions with a hands-on approach.
- Collaborate within a team of engineers, using best practices in software development such as design review, code reviews, testing, and continuous integration/continuous deployment (CI/CD).
- Build and maintain microservices architectures and APIs, ensuring seamless interoperability and data flow across platforms.
- Implement containerization solutions, particularly using Kubernetes, to support deployment and scaling needs.
- Collaborate with diverse technical teams, including R&D, Data Science, IT Operations, and AI/ML teams, to translate business requirements into technical solutions.
- Ensure optimal system performance, reliability, and security through proactive monitoring, automated testing, and continuous improvement.
- Troubleshoot complex technical issues in a complex microservice architecture, collaborating across teams to identify, resolve, and build future mitigation strategies.
- Monitor and track operational metrics.
- Ensure robust integration of AI/ML models into production environments, focusing on scalability, performance, and reliability.
BASIC QUALIFICATIONS
- Bachelor's degree in Computer Science, Information Technology, Software Engineering.
- Minimum 4 years of experience in architecture and software engineering.
PREFERRED QUALIFICATIONS
- Master's degree in Computer Science, Information Technology, Software Engineering.
- Proven track record of delivering complex, cross-functional IT solutions.
LOCATION & WORK FLEXIBILITY
This role is based at our Corporate Center in Indianapolis. We offer a flexible hybrid work model, with three days onsite and two days working remotely each week, supporting both collaboration and work-life balance.
- Remote employees will be considered for those not based near Indianapolis, IN.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $132,000 - $244,200.
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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Get Access To All JobsTips for Finding STEM OPT Authorization as a Clinical Informatics Specialist
Verify your CIP code before applying
Check that your degree's Classification of Instructional Programs code maps to an eligible STEM field. Health informatics and biomedical informatics degrees typically qualify, but confirm with your DSO before accepting any offer.
Confirm E-Verify enrollment before accepting
Ask the hiring team directly whether the employer is currently enrolled in E-Verify, not just registered. Enrollment status can lapse, and your STEM OPT authorization is invalid without an active, enrolled employer.
Target health systems filing I-983 training plans
Large hospital networks and integrated health systems run formal training programs and have HR teams experienced with I-983 documentation. Smaller clinics often lack the infrastructure to complete the training plan correctly.
Use Migrate Mate to filter verified employers
Search Clinical Informatics Specialist roles on Migrate Mate to find employers with confirmed E-Verify enrollment and OPT hiring history. This cuts the research time you'd otherwise spend vetting each employer manually.
Align your I-983 training goals with the job description
Write specific, measurable learning objectives tied to clinical data systems, EHR workflows, or interoperability standards. Generic training plans get rejected. Use the actual job responsibilities to draft goals your employer can evaluate.
Understand cap-gap protection if your H-1B is selected
If your OPT expires while an H-1B visa petition is pending after lottery selection, cap-gap rules extend your work authorization through September 30. USCIS requires your employer to have filed on time and for your status to remain valid at filing.
Frequently Asked Questions
Does a health informatics or biomedical informatics degree qualify for STEM OPT?
Health informatics and biomedical informatics degrees are listed under eligible STEM CIP codes, so graduates in those fields can apply for the 24-month STEM OPT extension. Computer science and information systems degrees used in clinical informatics roles also qualify. Confirm your specific CIP code with your DSO, since degree titles vary by institution and some programs use codes that fall outside the eligible list.
What does an employer need to do to support a STEM OPT extension for this role?
The employer must be enrolled in E-Verify and agree to complete Form I-983, the training plan document that outlines your learning goals, supervision structure, and how the role connects to your STEM degree. The employer also needs to report material changes in your role or compensation to your DSO. Clinical informatics positions held at health systems with dedicated HR teams tend to handle this process more reliably than smaller organizations.
How do I find Clinical Informatics Specialist jobs where the employer is already enrolled in E-Verify?
Browse Clinical Informatics Specialist listings on Migrate Mate, which surfaces employers with verified E-Verify enrollment so you don't need to vet each posting manually. You can also ask recruiters directly during the screening call, before investing time in interviews. Employers who've hired OPT students before will have active enrollment and existing I-983 processes in place.
What should the I-983 training plan include for a Clinical Informatics Specialist role?
The I-983 needs specific, measurable training objectives tied to your degree field, not just a description of your job duties. For clinical informatics, that means goals around EHR system implementation, clinical data analysis, interoperability standards, or decision-support tool development. Your supervisor's name, oversight frequency, and how the role advances your STEM education must all be documented. Vague plans citing only general professional development are the most common reason DSOs flag I-983 submissions for revision.
Can I switch employers during my STEM OPT extension as a Clinical Informatics Specialist?
Yes, but each employer change requires a new I-983 training plan and your DSO must update your SEVIS record before you start working for the new employer. The new employer must also be enrolled in E-Verify. You have up to 10 days of unemployment between positions without affecting your status, and cumulative unemployment across your entire OPT and STEM OPT period cannot exceed 150 days.