Sterile Processing Tech Jobs in South Carolina
Sterile Processing Tech jobs in South Carolina are open across Charleston, Columbia, and Florence and other South Carolina metros, with employers like Medical University of South Carolina, Prisma Health, and Novant Health hiring at every experience level. Find a role that fits below and apply directly.
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Inspire health. Serve with compassion. Be the difference.
Job Summary
Performs duties in Decontamination, Instrument Preparation and Assembly, and Sterilization/Disinfection relating to cleaning and sterilizing instruments and equipment to be used in patient care. Disassembles complex instruments, supplies and equipment; sorts and inspects for damage and reports needed repairs. Selects the mode of decontamination best suited for items on hand. Assembles, prepares and packages instrument trays, surgical instruments, equipment, and specialty items. Determines the appropriate sterilization or disinfection method and follows appropriate steps for reprocessing. Follows strict documentation guidelines for tray management, biological/chemical test results, equipment functionality, and reprocessing steps.
Essential Functions
- All team members are expected to be knowledgeable and compliant with Prisma Health's purpose: Inspire health. Serve with compassion. Be the difference.
- Receives, sorts, disassembles and processes contaminated instruments and equipment using the procedures and guidelines as established by Infection Control. Removes soil, blood, tissue fragments and body fluids by wiping, soaking, rinsing, scrubbing and using ultrasonic or other mechanical methods, as applicable.
- Assembles all instrument sets following prescribed manner and as outlined on the Instrument Count Sheets. Properly documents missing items from the set and labels sets correctly. Takes action to correct problems with instrument sets and reports any unresolved issues.
- Sterilizes instruments, equipment, linen and supplies using various types of autoclaves and aerators. Reprocesses equipment via high level disinfection as appropriate. Loads and operates machinery in prescribed manner and sets controls to correct specifications for the items being sterilized.
- Documents all activities related to instrument/equipment decontamination, assembly, disinfection, and sterilization in the Instrument Tracking System (SPM, Censitrac) or established manual systems.
- Observe and interpret biological, mechanical and chemical monitors relevant to processing/sterilizing. Record results and maintains required records. Initiates recalls as required.
- Issues items to customers and departments according to established procedures.
- Observes and reports to supervisor any unfamiliar items with or without appropriate processing literature. Reports equipment requiring repair as needed. Is self-directed and intervenes with corrections to variances in the processing practice.
- Models Prisma Health behavior expectations. Assists with coaching, mentoring and training coworkers as assigned. Trains and assists with integration of new team members. Shares knowledge, ideas and expertise to support the team and the department.
- Performs other duties as assigned.
Supervisory/Management Responsibility
This is a non-management job that will report to a supervisor, manager, director, or executive.
Minimum Requirements
- Education - Completion of job-related coursework: Surgical Tech, Sterile Processing Tech, or Dental Assistant training program.
- Experience - No experience required.
In Lieu Of
In lieu of the education requirement only, will accept High School diploma or equivalent and 6 months experience in a hospital or clinical setting.
Required Certifications, Registrations, Licenses
- Certification as either: CRCST (Certified Registered Central Service Technician) from HSPA (Healthcare Sterile Processing Association); OR CSPDT (Certified Sterile Processing & Distribution Technician) from CBSPD (Certification Board for Sterile Processing & Distribution) preferred.
- Applicants without sterile processing certification are required to obtain CRCST certification via HSPA within ONE (1) year of meeting the eligibility requirements to sit for the certification exam. Eligibility is defined by HSPA as "10 weeks (400 hours) experience" in a Sterile Processing hospital setting.
Knowledge, Skills and Abilities
NA
Work Shift
Day (United States of America)
Location
Greer Medical Campus
Facility
1004 Greer Memorial Hospital
Department
10048007 Central Sterile
Share your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.
See All 18 Sterile Processing Tech Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Sterile Processing Tech JobsSterile Processing Tech Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Sterile Processing Tech Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Medical University of South Carolina10

- Prisma Health7

- Novant Health1

Top Industries Hiring
- Healthcare & Medical Services12
- Education6
What South Carolina Employers Look For
The qualifications that appear most often in sterile processing tech jobs across South Carolina.
- CRCST certification through IAHCSMM or CBSPD equivalent preferred or required
- Hands-on experience with steam and low-temperature sterilization methods including ETO and hydrogen peroxide
- Proficiency operating and troubleshooting autoclave equipment such as STERIS or Getinge units
- Knowledge of AORN and AAMI standards for instrument decontamination and sterilization
- Ability to lift up to 50 pounds and stand for extended periods in a fast-paced environment
- High school diploma or GED with completion of an accredited sterile processing training program
Sterile Processing Tech Jobs in South Carolina: Frequently Asked Questions
How many sterile processing tech jobs are there in South Carolina?
There are 18+ sterile processing tech openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Charleston, Columbia, and Florence. New positions post regularly as employers across South Carolina hire.
How much do sterile processing teches make in South Carolina?
Sterile processing teches in South Carolina earn a median of about $42,510 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $31,840 for the lowest 10% to over $57,910 for the top 10%. Pay rises with experience, specialty, and employer.
Which South Carolina cities have the most sterile processing tech jobs?
Charleston, Columbia, and Florence have the most sterile processing tech openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire sterile processing techs in South Carolina?
Employers hiring sterile processing techs in South Carolina include Medical University of South Carolina, Prisma Health, and Novant Health, based on current listings on Migrate Mate as of June 2026.
Are there remote sterile processing tech jobs in South Carolina?
Yes. About 0% of sterile processing tech openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for sterile processing tech jobs in South Carolina?
You can apply to sterile processing tech jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 18 Sterile Processing Tech Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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