Data Science Analyst Visa Sponsorship Jobs in Massachusetts
Massachusetts is one of the strongest markets for data science analyst roles with visa sponsorship, driven by biotech and life sciences employers in Cambridge and Boston, major financial institutions along the Route 128 corridor, and a deep university pipeline from MIT, Harvard, and Northeastern feeding into companies like Biogen, Liberty Mutual, and Wayfair.
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Get Access To All JobsSEISMIC THERAPEUTIC
Director / Senior Director, Biometrics & Data Science
About Seismic
Seismic Therapeutic is a clinical-stage biotechnology company making a major shift in how immunology therapies are discovered and developed. The company has a growing preclinical stage best-in-class and first-in-class biologics pipeline, derived from its integrated IMPACT platform, to control dysregulated adaptive immunity and address multiple autoimmune diseases. The company is backed by a strong syndicate of life science investors and is located in the Boston area biotechnology hub.
At our core, we are focused on phenomenal science, supportive culture, a superstar team, meritocracy, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that. This is a terrific opportunity for a highly motivated, hands-on biostatistician and data scientist to build and lead the biometrics function and join our small, dynamic and high-performing Clinical Development team.
Job Summary
Seismic is seeking a biometrics and data science lead to join our growing Clinical and Development team. You will perform and oversee biostatistics for our clinical programs, combining hands-on statistical expertise with oversight of data management and statistical programming performed by CROs, following Seismic's externalized operating model.
You will also serve as the steward of Seismic's clinical and complex biomarker data, ensuring that data are organized, standardized, and linked to available biospecimens and external collaborations. As an integral member of the Clinical Development team, you will partner closely with colleagues in Immunology, Translational Sciences, Clinical Operations, and Regulatory.
This position may be filled at the Director or Senior Director level, depending on experience, technical leadership, and scope of prior responsibilities. Senior Director candidates should demonstrate broader ownership of biometrics strategy across programs, including vendor strategy and budgets, health authority interactions, and readiness to build and lead a team.
Key Responsibilities
- Conduct hands-on biostatistics for Seismic's clinical studies, including study design input, sample size calculations, authoring/reviewing statistical analysis plans, and performing and interpreting analyses. Provide statistical input to protocols, clinical study reports, regulatory submissions, and safety review committees, and oversee any biostatistics activities delegated to CROs.
- Oversee CRO data management from database build through lock, including eCRF and EDC design review, data management plans, edit checks, ongoing data review and reconciliation, and database lock readiness.
- Oversee CRO statistical programming, including SDTM and ADaM datasets and tables, listings, and figures, and independently review and validate key outputs. Select CRO biometrics partners and manage their scope, timelines, and performance.
- Organize clinical and biomarker data for each study and project in a compliant way and keep them current as new data arrive, including logs of issues that arise, how they are resolved, and which decisions are made.
- Coordinate data transfers from laboratories and biomarker vendors, and clean and standardize clinical and biomarker data, such as transcriptomics, proteomics, and flow cytometry, for integration and analysis.
- Perform exploratory analyses linking biomarkers to clinical outcomes.
- Partner closely with colleagues in Immunology, Biomarker & Translational Sciences, and Clinical Development, and Operations, to translate scientific and clinical questions into statistical and data deliverables.
- Build scalable biometrics practices, standards, and SOPs that support an expanding clinical pipeline without introducing unnecessary bureaucracy.
Required Qualifications
- Willingness to roll up your sleeves and take a hands-on approach to cleaning and standardizing data, creating a data-driven statistical analysis plan for each project, reviewing statistical deliverables, performing and/or overseeing analyses of clinical and multi-omic biomarker data, and driving activities to completion in a lean team environment.
- MS in biostatistics, statistics, or a related quantitative discipline and 8+ years of biostatistics experience in the biotechnology or pharmaceutical industry, or 12+ years for the Senior Director level.
- Hands-on experience designing clinical studies, authoring statistical analysis plans, and conducting analyses, with proficiency in relevant programming tools (e.g., SAS, R, Python).
- Proven experience overseeing CROs for biostatistics, statistical programming, and data management, with working knowledge of EDC systems and CDISC standards.
- Working knowledge of ICH-GCP and E9 guidelines and data integrity requirements for clinical data.
- Working familiarity with high-dimensional biomarker data and their integration with clinical trial data.
- Excellent written and verbal communication skills, strong organization and documentation discipline, and the ability to work effectively across internal teams and external partners.
Preferred Experience
- Experience supporting immunology, autoimmune, inflammatory, or allergic disease clinical programs.
- Experience with early-phase studies, biologics, and PK/PD data.
- Hands-on analysis of omics data, such as flow cytometry, bulk or single-cell transcriptomics.
- Experience as the first or sole statistician in a venture-backed biotechnology company or another lean environment, including management of academic collaborations.
Competencies
- Ownership and accountability for outcomes, balancing hands-on contribution with effective oversight.
- Statistical rigor and integrity, with sound judgment about what data can and cannot support.
- Operational discipline, maintaining careful attention to data quality, documentation, and traceability.
- Collaborative leadership that builds trust across disciplines and with CRO and external partners.
- Patient focus, connecting data integrity and analytical decisions to participant safety and the potential impact of Seismic's medicines for patients.
Other
This role is based in Watertown, Massachusetts, with in-office expectations consistent with Seismic's company policies and business needs.
Limited travel for collaborator, vendor, and scientific meetings, as needed.
The annual base salary range for this position is $200,000.00 - $315,000.00. Salary is determined by several factors including, but not limited to, relevant experience, skills, qualifications, education and internal benchmarks.
Seismic Therapeutic is an equal opportunity employer. We welcome applicants of every background and make employment decisions without regard to race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran status, pregnancy, genetic information, or any other status protected by federal, state, or local law. If you need an accommodation during the application or interview process, please let us know.
SEISMIC THERAPEUTIC
Director / Senior Director, Biometrics & Data Science
About Seismic
Seismic Therapeutic is a clinical-stage biotechnology company making a major shift in how immunology therapies are discovered and developed. The company has a growing preclinical stage best-in-class and first-in-class biologics pipeline, derived from its integrated IMPACT platform, to control dysregulated adaptive immunity and address multiple autoimmune diseases. The company is backed by a strong syndicate of life science investors and is located in the Boston area biotechnology hub.
At our core, we are focused on phenomenal science, supportive culture, a superstar team, meritocracy, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that. This is a terrific opportunity for a highly motivated, hands-on biostatistician and data scientist to build and lead the biometrics function and join our small, dynamic and high-performing Clinical Development team.
Job Summary
Seismic is seeking a biometrics and data science lead to join our growing Clinical and Development team. You will perform and oversee biostatistics for our clinical programs, combining hands-on statistical expertise with oversight of data management and statistical programming performed by CROs, following Seismic's externalized operating model.
You will also serve as the steward of Seismic's clinical and complex biomarker data, ensuring that data are organized, standardized, and linked to available biospecimens and external collaborations. As an integral member of the Clinical Development team, you will partner closely with colleagues in Immunology, Translational Sciences, Clinical Operations, and Regulatory.
This position may be filled at the Director or Senior Director level, depending on experience, technical leadership, and scope of prior responsibilities. Senior Director candidates should demonstrate broader ownership of biometrics strategy across programs, including vendor strategy and budgets, health authority interactions, and readiness to build and lead a team.
Key Responsibilities
- Conduct hands-on biostatistics for Seismic's clinical studies, including study design input, sample size calculations, authoring/reviewing statistical analysis plans, and performing and interpreting analyses. Provide statistical input to protocols, clinical study reports, regulatory submissions, and safety review committees, and oversee any biostatistics activities delegated to CROs.
- Oversee CRO data management from database build through lock, including eCRF and EDC design review, data management plans, edit checks, ongoing data review and reconciliation, and database lock readiness.
- Oversee CRO statistical programming, including SDTM and ADaM datasets and tables, listings, and figures, and independently review and validate key outputs. Select CRO biometrics partners and manage their scope, timelines, and performance.
- Organize clinical and biomarker data for each study and project in a compliant way and keep them current as new data arrive, including logs of issues that arise, how they are resolved, and which decisions are made.
- Coordinate data transfers from laboratories and biomarker vendors, and clean and standardize clinical and biomarker data, such as transcriptomics, proteomics, and flow cytometry, for integration and analysis.
- Perform exploratory analyses linking biomarkers to clinical outcomes.
- Partner closely with colleagues in Immunology, Biomarker & Translational Sciences, and Clinical Development, and Operations, to translate scientific and clinical questions into statistical and data deliverables.
- Build scalable biometrics practices, standards, and SOPs that support an expanding clinical pipeline without introducing unnecessary bureaucracy.
Required Qualifications
- Willingness to roll up your sleeves and take a hands-on approach to cleaning and standardizing data, creating a data-driven statistical analysis plan for each project, reviewing statistical deliverables, performing and/or overseeing analyses of clinical and multi-omic biomarker data, and driving activities to completion in a lean team environment.
- MS in biostatistics, statistics, or a related quantitative discipline and 8+ years of biostatistics experience in the biotechnology or pharmaceutical industry, or 12+ years for the Senior Director level.
- Hands-on experience designing clinical studies, authoring statistical analysis plans, and conducting analyses, with proficiency in relevant programming tools (e.g., SAS, R, Python).
- Proven experience overseeing CROs for biostatistics, statistical programming, and data management, with working knowledge of EDC systems and CDISC standards.
- Working knowledge of ICH-GCP and E9 guidelines and data integrity requirements for clinical data.
- Working familiarity with high-dimensional biomarker data and their integration with clinical trial data.
- Excellent written and verbal communication skills, strong organization and documentation discipline, and the ability to work effectively across internal teams and external partners.
Preferred Experience
- Experience supporting immunology, autoimmune, inflammatory, or allergic disease clinical programs.
- Experience with early-phase studies, biologics, and PK/PD data.
- Hands-on analysis of omics data, such as flow cytometry, bulk or single-cell transcriptomics.
- Experience as the first or sole statistician in a venture-backed biotechnology company or another lean environment, including management of academic collaborations.
Competencies
- Ownership and accountability for outcomes, balancing hands-on contribution with effective oversight.
- Statistical rigor and integrity, with sound judgment about what data can and cannot support.
- Operational discipline, maintaining careful attention to data quality, documentation, and traceability.
- Collaborative leadership that builds trust across disciplines and with CRO and external partners.
- Patient focus, connecting data integrity and analytical decisions to participant safety and the potential impact of Seismic's medicines for patients.
Other
This role is based in Watertown, Massachusetts, with in-office expectations consistent with Seismic's company policies and business needs.
Limited travel for collaborator, vendor, and scientific meetings, as needed.
The annual base salary range for this position is $200,000.00 - $315,000.00. Salary is determined by several factors including, but not limited to, relevant experience, skills, qualifications, education and internal benchmarks.
Seismic Therapeutic is an equal opportunity employer. We welcome applicants of every background and make employment decisions without regard to race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran status, pregnancy, genetic information, or any other status protected by federal, state, or local law. If you need an accommodation during the application or interview process, please let us know.
Data Science Analyst Job Roles in Massachusetts
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Search Data Science Analyst Jobs in MassachusettsData Science Analyst Jobs in Massachusetts: Frequently Asked Questions
Which companies sponsor visas for data science analysts in Massachusetts?
Massachusetts employers with consistent H-1B visa sponsorship records for data science analyst roles include Biogen, Takeda, and Vertex Pharmaceuticals in the biotech sector, along with Wayfair, HubSpot, and Fidelity Investments in tech and financial services. Massachusetts General Hospital and academic medical centers also sponsor data science roles, particularly for analysts working on clinical and research datasets. DOL LCA disclosure data is the most reliable way to verify which employers have filed recently.
Which visa types are most common for data science analyst roles in Massachusetts?
The H-1B is the most common visa category for data science analyst positions in Massachusetts, as the role typically qualifies as a specialty occupation requiring at least a bachelor's degree in statistics, computer science, mathematics, or a related field. Some employers also sponsor OPT STEM extensions, allowing F-1 graduates an additional 24 months of work authorization before needing H-1B sponsorship. Australian nationals may also find E-3 visa sponsorship with larger Massachusetts employers.
Which cities in Massachusetts have the most data science analyst sponsorship jobs?
Boston and Cambridge account for the majority of data science analyst sponsorship activity in Massachusetts, anchored by the Kendall Square biotech cluster and the Seaport District's growing tech presence. Waltham and Burlington along Route 128 are significant secondary hubs, hosting financial services firms and enterprise software companies. Worcester has a smaller but active market, supported by UMass Medical School and regional healthcare employers.
How to find data science analyst visa sponsorship jobs in Massachusetts?
Migrate Mate filters data science analyst roles specifically to employers who sponsor work visas, saving you from manually screening hundreds of job listings. You can narrow results to Massachusetts to surface openings in Boston, Cambridge, and the Route 128 corridor. Because sponsorship willingness is built into the filtering, you're seeing roles where the employer has already demonstrated a history of petitioning for international candidates in data-focused positions.
Are there any Massachusetts-specific factors that affect visa sponsorship for data science analysts?
Massachusetts has a high concentration of life sciences and biotech employers, which tend to sponsor visas at above-average rates because the talent pool for specialized data science work in clinical and genomic research is globally sourced. The state's prevailing wage requirements under DOL LCA rules mean employers must offer wages benchmarked to Massachusetts market rates, which are competitive given the cost of living in Greater Boston. The dense university ecosystem also means many candidates enter the job market on OPT, making employers in the state familiar with F-1 to H-1B transitions.
What is the prevailing wage for sponsored data science analyst jobs in Massachusetts?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.