Data Science Engineer Visa Sponsorship Jobs in Massachusetts
Data science engineer jobs in Massachusetts are concentrated in Boston, Cambridge, and the Route 128 corridor, where employers like Amazon, IBM, and a dense network of biotech and fintech firms actively hire for these roles. The state's proximity to MIT, Harvard, and Northeastern creates a strong pipeline that many of these companies sponsor through H-1B visa and other work visa categories.
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Get Access To All JobsSEISMIC THERAPEUTIC
Director / Senior Director, Biometrics & Data Science
About Seismic
Seismic Therapeutic is a clinical-stage biotechnology company making a major shift in how immunology therapies are discovered and developed. The company has a growing preclinical stage best-in-class and first-in-class biologics pipeline, derived from its integrated IMPACT platform, to control dysregulated adaptive immunity and address multiple autoimmune diseases. The company is backed by a strong syndicate of life science investors and is located in the Boston area biotechnology hub.
At our core, we are focused on phenomenal science, supportive culture, a superstar team, meritocracy, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that. This is a terrific opportunity for a highly motivated, hands-on biostatistician and data scientist to build and lead the biometrics function and join our small, dynamic and high-performing Clinical Development team.
Job Summary
Seismic is seeking a biometrics and data science lead to join our growing Clinical and Development team. You will perform and oversee biostatistics for our clinical programs, combining hands-on statistical expertise with oversight of data management and statistical programming performed by CROs, following Seismic's externalized operating model.
You will also serve as the steward of Seismic's clinical and complex biomarker data, ensuring that data are organized, standardized, and linked to available biospecimens and external collaborations. As an integral member of the Clinical Development team, you will partner closely with colleagues in Immunology, Translational Sciences, Clinical Operations, and Regulatory.
This position may be filled at the Director or Senior Director level, depending on experience, technical leadership, and scope of prior responsibilities. Senior Director candidates should demonstrate broader ownership of biometrics strategy across programs, including vendor strategy and budgets, health authority interactions, and readiness to build and lead a team.
Key Responsibilities
- Conduct hands-on biostatistics for Seismic's clinical studies, including study design input, sample size calculations, authoring/reviewing statistical analysis plans, and performing and interpreting analyses. Provide statistical input to protocols, clinical study reports, regulatory submissions, and safety review committees, and oversee any biostatistics activities delegated to CROs.
- Oversee CRO data management from database build through lock, including eCRF and EDC design review, data management plans, edit checks, ongoing data review and reconciliation, and database lock readiness.
- Oversee CRO statistical programming, including SDTM and ADaM datasets and tables, listings, and figures, and independently review and validate key outputs. Select CRO biometrics partners and manage their scope, timelines, and performance.
- Organize clinical and biomarker data for each study and project in a compliant way and keep them current as new data arrive, including logs of issues that arise, how they are resolved, and which decisions are made.
- Coordinate data transfers from laboratories and biomarker vendors, and clean and standardize clinical and biomarker data, such as transcriptomics, proteomics, and flow cytometry, for integration and analysis.
- Perform exploratory analyses linking biomarkers to clinical outcomes.
- Partner closely with colleagues in Immunology, Biomarker & Translational Sciences, and Clinical Development, and Operations, to translate scientific and clinical questions into statistical and data deliverables.
- Build scalable biometrics practices, standards, and SOPs that support an expanding clinical pipeline without introducing unnecessary bureaucracy.
Required Qualifications
- Willingness to roll up your sleeves and take a hands-on approach to cleaning and standardizing data, creating a data-driven statistical analysis plan for each project, reviewing statistical deliverables, performing and/or overseeing analyses of clinical and multi-omic biomarker data, and driving activities to completion in a lean team environment.
- MS in biostatistics, statistics, or a related quantitative discipline and 8+ years of biostatistics experience in the biotechnology or pharmaceutical industry, or 12+ years for the Senior Director level.
- Hands-on experience designing clinical studies, authoring statistical analysis plans, and conducting analyses, with proficiency in relevant programming tools (e.g., SAS, R, Python).
- Proven experience overseeing CROs for biostatistics, statistical programming, and data management, with working knowledge of EDC systems and CDISC standards.
- Working knowledge of ICH-GCP and E9 guidelines and data integrity requirements for clinical data.
- Working familiarity with high-dimensional biomarker data and their integration with clinical trial data.
- Excellent written and verbal communication skills, strong organization and documentation discipline, and the ability to work effectively across internal teams and external partners.
Preferred Experience
- Experience supporting immunology, autoimmune, inflammatory, or allergic disease clinical programs.
- Experience with early-phase studies, biologics, and PK/PD data.
- Hands-on analysis of omics data, such as flow cytometry, bulk or single-cell transcriptomics.
- Experience as the first or sole statistician in a venture-backed biotechnology company or another lean environment, including management of academic collaborations.
Competencies
- Ownership and accountability for outcomes, balancing hands-on contribution with effective oversight.
- Statistical rigor and integrity, with sound judgment about what data can and cannot support.
- Operational discipline, maintaining careful attention to data quality, documentation, and traceability.
- Collaborative leadership that builds trust across disciplines and with CRO and external partners.
- Patient focus, connecting data integrity and analytical decisions to participant safety and the potential impact of Seismic's medicines for patients.
Other
This role is based in Watertown, Massachusetts, with in-office expectations consistent with Seismic's company policies and business needs.
Limited travel for collaborator, vendor, and scientific meetings, as needed.
The annual base salary range for this position is $200,000.00 - $315,000.00. Salary is determined by several factors including, but not limited to, relevant experience, skills, qualifications, education and internal benchmarks.
Seismic Therapeutic is an equal opportunity employer. We welcome applicants of every background and make employment decisions without regard to race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran status, pregnancy, genetic information, or any other status protected by federal, state, or local law. If you need an accommodation during the application or interview process, please let us know.
SEISMIC THERAPEUTIC
Director / Senior Director, Biometrics & Data Science
About Seismic
Seismic Therapeutic is a clinical-stage biotechnology company making a major shift in how immunology therapies are discovered and developed. The company has a growing preclinical stage best-in-class and first-in-class biologics pipeline, derived from its integrated IMPACT platform, to control dysregulated adaptive immunity and address multiple autoimmune diseases. The company is backed by a strong syndicate of life science investors and is located in the Boston area biotechnology hub.
At our core, we are focused on phenomenal science, supportive culture, a superstar team, meritocracy, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that. This is a terrific opportunity for a highly motivated, hands-on biostatistician and data scientist to build and lead the biometrics function and join our small, dynamic and high-performing Clinical Development team.
Job Summary
Seismic is seeking a biometrics and data science lead to join our growing Clinical and Development team. You will perform and oversee biostatistics for our clinical programs, combining hands-on statistical expertise with oversight of data management and statistical programming performed by CROs, following Seismic's externalized operating model.
You will also serve as the steward of Seismic's clinical and complex biomarker data, ensuring that data are organized, standardized, and linked to available biospecimens and external collaborations. As an integral member of the Clinical Development team, you will partner closely with colleagues in Immunology, Translational Sciences, Clinical Operations, and Regulatory.
This position may be filled at the Director or Senior Director level, depending on experience, technical leadership, and scope of prior responsibilities. Senior Director candidates should demonstrate broader ownership of biometrics strategy across programs, including vendor strategy and budgets, health authority interactions, and readiness to build and lead a team.
Key Responsibilities
- Conduct hands-on biostatistics for Seismic's clinical studies, including study design input, sample size calculations, authoring/reviewing statistical analysis plans, and performing and interpreting analyses. Provide statistical input to protocols, clinical study reports, regulatory submissions, and safety review committees, and oversee any biostatistics activities delegated to CROs.
- Oversee CRO data management from database build through lock, including eCRF and EDC design review, data management plans, edit checks, ongoing data review and reconciliation, and database lock readiness.
- Oversee CRO statistical programming, including SDTM and ADaM datasets and tables, listings, and figures, and independently review and validate key outputs. Select CRO biometrics partners and manage their scope, timelines, and performance.
- Organize clinical and biomarker data for each study and project in a compliant way and keep them current as new data arrive, including logs of issues that arise, how they are resolved, and which decisions are made.
- Coordinate data transfers from laboratories and biomarker vendors, and clean and standardize clinical and biomarker data, such as transcriptomics, proteomics, and flow cytometry, for integration and analysis.
- Perform exploratory analyses linking biomarkers to clinical outcomes.
- Partner closely with colleagues in Immunology, Biomarker & Translational Sciences, and Clinical Development, and Operations, to translate scientific and clinical questions into statistical and data deliverables.
- Build scalable biometrics practices, standards, and SOPs that support an expanding clinical pipeline without introducing unnecessary bureaucracy.
Required Qualifications
- Willingness to roll up your sleeves and take a hands-on approach to cleaning and standardizing data, creating a data-driven statistical analysis plan for each project, reviewing statistical deliverables, performing and/or overseeing analyses of clinical and multi-omic biomarker data, and driving activities to completion in a lean team environment.
- MS in biostatistics, statistics, or a related quantitative discipline and 8+ years of biostatistics experience in the biotechnology or pharmaceutical industry, or 12+ years for the Senior Director level.
- Hands-on experience designing clinical studies, authoring statistical analysis plans, and conducting analyses, with proficiency in relevant programming tools (e.g., SAS, R, Python).
- Proven experience overseeing CROs for biostatistics, statistical programming, and data management, with working knowledge of EDC systems and CDISC standards.
- Working knowledge of ICH-GCP and E9 guidelines and data integrity requirements for clinical data.
- Working familiarity with high-dimensional biomarker data and their integration with clinical trial data.
- Excellent written and verbal communication skills, strong organization and documentation discipline, and the ability to work effectively across internal teams and external partners.
Preferred Experience
- Experience supporting immunology, autoimmune, inflammatory, or allergic disease clinical programs.
- Experience with early-phase studies, biologics, and PK/PD data.
- Hands-on analysis of omics data, such as flow cytometry, bulk or single-cell transcriptomics.
- Experience as the first or sole statistician in a venture-backed biotechnology company or another lean environment, including management of academic collaborations.
Competencies
- Ownership and accountability for outcomes, balancing hands-on contribution with effective oversight.
- Statistical rigor and integrity, with sound judgment about what data can and cannot support.
- Operational discipline, maintaining careful attention to data quality, documentation, and traceability.
- Collaborative leadership that builds trust across disciplines and with CRO and external partners.
- Patient focus, connecting data integrity and analytical decisions to participant safety and the potential impact of Seismic's medicines for patients.
Other
This role is based in Watertown, Massachusetts, with in-office expectations consistent with Seismic's company policies and business needs.
Limited travel for collaborator, vendor, and scientific meetings, as needed.
The annual base salary range for this position is $200,000.00 - $315,000.00. Salary is determined by several factors including, but not limited to, relevant experience, skills, qualifications, education and internal benchmarks.
Seismic Therapeutic is an equal opportunity employer. We welcome applicants of every background and make employment decisions without regard to race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran status, pregnancy, genetic information, or any other status protected by federal, state, or local law. If you need an accommodation during the application or interview process, please let us know.
Data Science Engineer Job Roles in Massachusetts
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Search Data Science Engineer Jobs in MassachusettsData Science Engineer Jobs in Massachusetts: Frequently Asked Questions
Which companies sponsor visas for data science engineers in Massachusetts?
Large technology and life sciences employers are among the most active sponsors in Massachusetts. Companies like Amazon, IBM, Biogen, Wayfair, and MathWorks have consistent H-1B filing histories for data science and machine learning roles. Boston-area financial services firms, including Fidelity Investments and State Street, also sponsor data science engineers with regularity. Sponsorship activity is heaviest among companies with established legal and HR infrastructure to manage the process.
Which visa types are most common for data science engineer roles in Massachusetts?
The H-1B is the most common visa category for data science engineer roles in Massachusetts, as the position typically qualifies as a specialty occupation requiring at least a bachelor's degree in computer science, statistics, or a related field. Candidates already in the U.S. on F-1 OPT or STEM OPT extension are frequently hired before transitioning to H-1B sponsorship. The O-1A is an option for candidates with demonstrated distinction in their field, though it requires substantial documentation.
Which cities in Massachusetts have the most data science engineer sponsorship jobs?
Boston and Cambridge account for the largest share of data science engineer sponsorship jobs in Massachusetts, driven by the concentration of technology companies, financial institutions, and life sciences employers in those cities. Waltham and Burlington along the Route 128 corridor are also significant hubs, hosting mid-size and enterprise technology firms. Worcester and Lowell have smaller but growing data and analytics hiring activity, often tied to healthcare systems and regional technology employers.
How to find data science engineer visa sponsorship jobs in Massachusetts?
Migrate Mate is built specifically for international job seekers and filters data science engineer roles in Massachusetts by visa sponsorship. Rather than sorting through postings that don't address sponsorship, Migrate Mate surfaces employers with a documented history of sponsoring work visas for technical roles. Filtering by state and job category helps narrow results to Massachusetts-based positions that are realistically accessible to candidates who need H-1B or other visa support.
Are there state-specific factors that affect data science engineer visa sponsorship in Massachusetts?
Massachusetts employers filing H-1B petitions must meet Department of Labor prevailing wage requirements based on the specific job location, and Boston and Cambridge wages reflect a high-cost metropolitan area. The state's deep university ecosystem means many employers are familiar with OPT-to-H-1B transitions and have existing immigration counsel in place. Life sciences and fintech companies in particular tend to have structured sponsorship processes, which can make the experience more consistent than smaller or less experienced employers.
What is the prevailing wage for sponsored data science engineer jobs in Massachusetts?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.