Software Engineer Visa Sponsorship Jobs in Missouri
Missouri's software engineer job market is anchored by employers like Cerner (now Oracle Health) in Kansas City, World Wide Technology in St. Louis, and a growing fintech and healthcare IT sector statewide. Both cities host active tech communities with a documented history of H-1B visa sponsorship, making Missouri a practical target for international software engineers seeking U.S. visa sponsorship.
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Get Access To All JobsWhat Quality Engineering contributes to Cardinal Health
Quality develops and implements quality policies, procedures, and processes to ensure products and services comply with regulatory standards and specifications.
Quality Engineering manages product and service quality planning, evaluation and control. This job family works cross-functionally in the development and implementation of prevention-based methodologies used in designing, manufacturing, testing, and correction of products and services.
Job Summary
The Product Software Design Quality Engineer provides independent quality oversight throughout the life cycle of medical device software. The role ensures effective software design controls, risk management, verification and validation, cybersecurity, change control, and post-market support to maintain safe, effective, and compliant products.
Primary focus areas:
- Software Design Control: Review and approve software plans, requirements, architecture, traceability, verification and validation, anomaly assessments, design transfer, release, and maintenance activities.
- Software Risk Management: Ensure software and cybersecurity risks are identified, evaluated, controlled, verified, and monitored throughout the product life cycle.
This position follows a hybrid work model and requires regular on-site presence to support cross-functional collaboration, stakeholder engagement, and key business activities. The specific frequency of on-site attendance may vary based on business needs, project requirements, and team objectives.
Responsibilities
- Applies advanced knowledge and understanding of concepts, principles, and technical capabilities to manage a wide variety of projects.
- Participates in the development of policies and procedures to achieve specific goals.
- Recommends new practices, processes, metrics, or models.
- Works on or may lead complex projects of large scope.
- Projects may have significant and long-term impact.
- Provides solutions which may set precedent.
- Review and approve software life cycle deliverables, including plans, requirements, design documentation, traceability, verification and validation, configuration records, anomaly assessments, and release documentation.
- Evaluate defects, anomalies, deviations, test failures, and unresolved issues for safety, quality, cybersecurity, regulatory, and release impact. Escalate high-risk issues as appropriate.
- Independently determines method for completion of new projects.
- Receives guidance on overall project objectives.
- Acts as a mentor to less experienced colleagues.
Qualifications
- Bachelor’s degree in related field, or equivalent work experience, preferred.
- 8-12 years of experience in software quality, design quality, software validation, software development, systems engineering, or a related regulated-industry role, preferred.
- Experience with medical device software and application of design controls, IEC 62304 software life cycle processes, ISO 14971 risk management, verification and validation, configuration management, and change control, preferred.
- Working knowledge of 21 CFR Part 820, ISO 13485, IEC 62304, ISO 14971, IEC 62366-1, IEC 60601, applicable FDA software guidance, and medical device cybersecurity expectations, preferred.
- Experience with requirements and traceability, software testing, anomaly management, root cause analysis, CAPA, and audit support, preferred.
- Strong technical writing, problem-solving, organizational, communication, and cross-functional collaboration skills, preferred.
- Experience with embedded software, firmware, connected devices, cloud platforms, mobile applications, Software as a Medical Device, or Class II/III medical devices, preferred.
- ASQ, software quality, cybersecurity, or related certification, preferred.
What is expected of you and others at this level
- Applies advanced knowledge and understanding of concepts, principles, and technical capabilities to manage a wide variety of projects.
- Participates in the development of policies and procedures to achieve specific goals.
- Recommends new practices, processes, metrics, or models.
- Works on or may lead complex projects of large scope.
- Projects may have significant and long-term impact.
- Provides solutions which may set precedent.
- Review and approve software life cycle deliverables, including plans, requirements, design documentation, traceability, verification and validation, configuration records, anomaly assessments, and release documentation.
- Evaluate defects, anomalies, deviations, test failures, and unresolved issues for safety, quality, cybersecurity, regulatory, and release impact. Escalate high-risk issues as appropriate.
- Independently determines method for completion of new projects.
- Receives guidance on overall project objectives.
- Acts as a mentor to less experienced colleagues.
Anticipated salary range: $106,700 - $152,400
Bonus eligible: Yes
Benefits: Cardinal Health offers a wide variety of benefits and programs to support health and well-being.
- Medical, dental and vision coverage
- Paid time off plan
- Health savings account (HSA)
- 401k savings plan
- Access to wages before pay day with myFlexPay
- Flexible spending accounts (FSAs)
- Short- and long-term disability coverage
- Work-Life resources
- Paid parental leave
- Healthy lifestyle programs
Application window anticipated to close: 11/6/2026 *if interested in opportunity, please submit application as soon as possible.
The salary range listed is an estimate. Pay at Cardinal Health is determined by multiple factors including, but not limited to, a candidate’s geographical location, relevant education, experience and skills and an evaluation of internal pay equity.
LI-MP1
LI-hybrid
Candidates who are back-to-work, people with disabilities, without a college degree, and Veterans are encouraged to apply.
Cardinal Health supports an inclusive workplace that values diversity of thought, experience and background. We celebrate the power of our differences to create better solutions for our customers by ensuring employees can be their authentic selves each day. Cardinal Health is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, ancestry, age, physical or mental disability, sex, sexual orientation, gender identity/expression, pregnancy, veteran status, marital status, creed, status with regard to public assistance, genetic status or any other status protected by federal, state or local law.
What Quality Engineering contributes to Cardinal Health
Quality develops and implements quality policies, procedures, and processes to ensure products and services comply with regulatory standards and specifications.
Quality Engineering manages product and service quality planning, evaluation and control. This job family works cross-functionally in the development and implementation of prevention-based methodologies used in designing, manufacturing, testing, and correction of products and services.
Job Summary
The Product Software Design Quality Engineer provides independent quality oversight throughout the life cycle of medical device software. The role ensures effective software design controls, risk management, verification and validation, cybersecurity, change control, and post-market support to maintain safe, effective, and compliant products.
Primary focus areas:
- Software Design Control: Review and approve software plans, requirements, architecture, traceability, verification and validation, anomaly assessments, design transfer, release, and maintenance activities.
- Software Risk Management: Ensure software and cybersecurity risks are identified, evaluated, controlled, verified, and monitored throughout the product life cycle.
This position follows a hybrid work model and requires regular on-site presence to support cross-functional collaboration, stakeholder engagement, and key business activities. The specific frequency of on-site attendance may vary based on business needs, project requirements, and team objectives.
Responsibilities
- Applies advanced knowledge and understanding of concepts, principles, and technical capabilities to manage a wide variety of projects.
- Participates in the development of policies and procedures to achieve specific goals.
- Recommends new practices, processes, metrics, or models.
- Works on or may lead complex projects of large scope.
- Projects may have significant and long-term impact.
- Provides solutions which may set precedent.
- Review and approve software life cycle deliverables, including plans, requirements, design documentation, traceability, verification and validation, configuration records, anomaly assessments, and release documentation.
- Evaluate defects, anomalies, deviations, test failures, and unresolved issues for safety, quality, cybersecurity, regulatory, and release impact. Escalate high-risk issues as appropriate.
- Independently determines method for completion of new projects.
- Receives guidance on overall project objectives.
- Acts as a mentor to less experienced colleagues.
Qualifications
- Bachelor’s degree in related field, or equivalent work experience, preferred.
- 8-12 years of experience in software quality, design quality, software validation, software development, systems engineering, or a related regulated-industry role, preferred.
- Experience with medical device software and application of design controls, IEC 62304 software life cycle processes, ISO 14971 risk management, verification and validation, configuration management, and change control, preferred.
- Working knowledge of 21 CFR Part 820, ISO 13485, IEC 62304, ISO 14971, IEC 62366-1, IEC 60601, applicable FDA software guidance, and medical device cybersecurity expectations, preferred.
- Experience with requirements and traceability, software testing, anomaly management, root cause analysis, CAPA, and audit support, preferred.
- Strong technical writing, problem-solving, organizational, communication, and cross-functional collaboration skills, preferred.
- Experience with embedded software, firmware, connected devices, cloud platforms, mobile applications, Software as a Medical Device, or Class II/III medical devices, preferred.
- ASQ, software quality, cybersecurity, or related certification, preferred.
What is expected of you and others at this level
- Applies advanced knowledge and understanding of concepts, principles, and technical capabilities to manage a wide variety of projects.
- Participates in the development of policies and procedures to achieve specific goals.
- Recommends new practices, processes, metrics, or models.
- Works on or may lead complex projects of large scope.
- Projects may have significant and long-term impact.
- Provides solutions which may set precedent.
- Review and approve software life cycle deliverables, including plans, requirements, design documentation, traceability, verification and validation, configuration records, anomaly assessments, and release documentation.
- Evaluate defects, anomalies, deviations, test failures, and unresolved issues for safety, quality, cybersecurity, regulatory, and release impact. Escalate high-risk issues as appropriate.
- Independently determines method for completion of new projects.
- Receives guidance on overall project objectives.
- Acts as a mentor to less experienced colleagues.
Anticipated salary range: $106,700 - $152,400
Bonus eligible: Yes
Benefits: Cardinal Health offers a wide variety of benefits and programs to support health and well-being.
- Medical, dental and vision coverage
- Paid time off plan
- Health savings account (HSA)
- 401k savings plan
- Access to wages before pay day with myFlexPay
- Flexible spending accounts (FSAs)
- Short- and long-term disability coverage
- Work-Life resources
- Paid parental leave
- Healthy lifestyle programs
Application window anticipated to close: 11/6/2026 *if interested in opportunity, please submit application as soon as possible.
The salary range listed is an estimate. Pay at Cardinal Health is determined by multiple factors including, but not limited to, a candidate’s geographical location, relevant education, experience and skills and an evaluation of internal pay equity.
LI-MP1
LI-hybrid
Candidates who are back-to-work, people with disabilities, without a college degree, and Veterans are encouraged to apply.
Cardinal Health supports an inclusive workplace that values diversity of thought, experience and background. We celebrate the power of our differences to create better solutions for our customers by ensuring employees can be their authentic selves each day. Cardinal Health is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, ancestry, age, physical or mental disability, sex, sexual orientation, gender identity/expression, pregnancy, veteran status, marital status, creed, status with regard to public assistance, genetic status or any other status protected by federal, state or local law.
Software Engineer Job Roles in Missouri
See all 188+ Software Engineer Jobs in Missouri
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Search Software Engineer Jobs in MissouriSoftware Engineer Jobs in Missouri: Frequently Asked Questions
Which companies sponsor visas for software engineers in Missouri?
Kansas City and St. Louis are home to Missouri's most active sponsors. Oracle Health (formerly Cerner), World Wide Technology, Centene Corporation, Edward Jones, and Mastercard's St. Louis operations have all filed H-1B Labor Condition Applications for software engineering roles. Large enterprise technology and financial services employers in the state tend to have established immigration processes and legal teams familiar with sponsoring international engineers.
Which visa types are most common for software engineer roles in Missouri?
The H-1B is the most common visa category for software engineers in Missouri, as the role consistently qualifies as a specialty occupation requiring a bachelor's degree or higher in computer science, software engineering, or a related field. Some engineers also enter on L-1B visas when transferring within a multinational employer. Canadian and Mexican nationals may qualify for the TN visa under the USMCA, which covers engineers and computer systems analysts.
Which cities in Missouri have the most software engineer sponsorship jobs?
Kansas City and St. Louis account for the large majority of software engineer sponsorship activity in Missouri. Kansas City has a strong healthcare IT concentration, driven by Oracle Health and related companies in that ecosystem. St. Louis has broader employer diversity across financial services, logistics, and defense contracting. Columbia, home to the University of Missouri, has a smaller but active tech employment base, particularly around university-affiliated research and startups.
How to find software engineer visa sponsorship jobs in Missouri?
Migrate Mate filters job listings specifically by visa sponsorship availability, so you can search software engineer roles in Missouri without manually vetting each employer. The platform aggregates positions from companies with a documented history of sponsoring international candidates, covering both Kansas City and St. Louis tech hubs. Filtering by role and state lets you focus your applications on employers already set up to handle the H-1B or other relevant visa processes.
Are there any Missouri-specific considerations for software engineers seeking visa sponsorship?
Missouri benefits from a lower cost of living relative to coastal tech hubs, which affects prevailing wage benchmarks that employers must meet under H-1B rules. The state's strong university pipeline, including graduates from the University of Missouri, Missouri University of Science and Technology, and Washington University in St. Louis, means many local employers are already familiar with OPT and STEM OPT extensions before a full H-1B petition. Healthcare IT is a particularly active hiring sector due to Missouri's outsized presence in that industry.
What is the prevailing wage for sponsored software engineer jobs in Missouri?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.