Senior Researcher Visa Sponsorship Jobs in New York
New York is one of the most active states for senior researcher visa sponsorship, with major employers spanning pharmaceutical giants in Manhattan, life sciences firms in the Hudson Valley, and leading research universities including Columbia, Cornell, and NYU. Federal agencies and think tanks headquartered in New York City add further depth to the hiring pool.
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Get Access To All JobsINTRODUCTION
The Holmes Lab is looking for a postdoctoral researcher to join our lab to carry out research projects related to innate immunity and pathogenesis in arthritogenic alphavirus infections. Our research focuses on defining the tissue tropism of emerging arthritogenic alphaviruses and determining how cells that are permissive to infection influence virus dissemination and disease progression.
Our most recent published work demonstrated that, in contrast to established paradigms, there are two phases of alphavirus transport through the lymphatics at early times of infection, one that precedes viral replication, and a second that requires replication in the skin which enables transit to the bloodstream (Holmes AC et al., doi: 10.1016/j.celrep.2024.113876). We found that skin-infiltrating Ly6Chi monocytes promote infection of several non-hematopoietic cell types in the skin. Unexpectedly, in contrast to the skin, lymph node-associated monocytes are refractory to virus infection. Our work highlighted that there is an underappreciated role for cell-free, fluid-phase lymphatic trafficking during early alphavirus dissemination and that there may be tissue-specific signals that govern monocyte permissiveness to alphavirus infection. Our aim is to identify and define the mechanisms that drive monocyte heterogeneity in arthritogenic alphavirus infections. In a forthcoming manuscript (Holmes AC et al., submitted, PLoS Pathogens), we have identified a subset of platelet-derived growth factor alpha-positive (PDGFRα+) skeletal muscle mesenchymal cells that are infected via the major arthritogenic alphavirus entry receptor, matrix remodeling-associated protein 8 (MXRA8). Infection of this PDGFRα+ cell subset increases local vascular permeability to mediate virus spread directly to the bloodstream in a manner that is dependent on vascular endothelial growth factor (VEGF) signaling. Our aim is to define the molecular events that underlie the VEGF signaling cascade during arthritogenic alphavirus infections.
DUTIES
Duties will include:
- The candidate will be trained on and perform in vitro and in vivo experiments related to arthritogenic alphavirus infections
- The candidate will carry out qRT-PCR on mouse tissues
- The candidate will carry out flow cytometry
- The candidate will carry out microscopy and imaging of mouse tissues
- The candidate will generate and maintain primary cell lines from mice and commercially available cell lines and carry out arthritogenic alphavirus infections in both primary cells and cell lines
- The candidate will develop projects involving methods such as single-cell and spatial RNAseq
- The candidate will prepare manuscripts for publication
- The candidate will be required to work at both BSL-2 and BSL-3 and will receive the appropriate institutional safety training
We are a new lab supported by funding from the Howard Hughes Medical Institute (HHMI) and are looking to grow! The lab is committed to the success of all members and provides mentorship and opportunities for research and career development. We are located at the Jacobs School of Medicine and Biomedical Sciences in downtown Buffalo, NY.
BENEFITS
Working at UB comes with benefits that exceed salary alone. There are personal rewards including comprehensive health and retirement plan options. We also focus on creating and sustaining a healthy mix of work, personal and academic pursuit – all in an effort to support your work-life effectiveness. We support your growth and development through our career coaching and training department and we qualify as a public service loan forgiveness organization. Learn more about the great benefits the University at Buffalo has to offer.
MINIMUM QUALIFICATIONS
- PhD in Virology, Immunology, Microbiology, Molecular Biology, or a related field
- Expertise in some of the following areas: in vivo pathogenesis, flow cytometry, molecular virology, qPCR, confocal fluorescence microscopy, histology
- Highly motivated
- Possesses ability to work independently and collaboratively within a small team
- Time management and organizational skills
- Strong oral and written communication skills
- Mentorship experiences in the lab
PREFERRED QUALIFICATIONS
- Expertise in single-cell and/or spatial RNAseq and bioinformatics (not required but preferred)
- Expertise in live-animal imaging (not required but preferred)
PHYSICAL DEMANDS
DRIVING REQUIREMENTS
This position will never drive a university owned vehicle.
SALARY RANGE
$60,000 - $64,000
The salary range reflects our good faith and reasonable estimate of the possible compensation at the time of posting, the role and associated responsibilities, and the experience, education, and training of the selected candidate.
WORK HOURS
40
CAMPUS
Downtown Campus
BACKGROUND CHECK NOTIFICATION
Is a background check required for this posting? No
The Research Foundation of SUNY is an EOE and welcomes all to apply including veterans and individuals with a disability.
INTRODUCTION
The Holmes Lab is looking for a postdoctoral researcher to join our lab to carry out research projects related to innate immunity and pathogenesis in arthritogenic alphavirus infections. Our research focuses on defining the tissue tropism of emerging arthritogenic alphaviruses and determining how cells that are permissive to infection influence virus dissemination and disease progression.
Our most recent published work demonstrated that, in contrast to established paradigms, there are two phases of alphavirus transport through the lymphatics at early times of infection, one that precedes viral replication, and a second that requires replication in the skin which enables transit to the bloodstream (Holmes AC et al., doi: 10.1016/j.celrep.2024.113876). We found that skin-infiltrating Ly6Chi monocytes promote infection of several non-hematopoietic cell types in the skin. Unexpectedly, in contrast to the skin, lymph node-associated monocytes are refractory to virus infection. Our work highlighted that there is an underappreciated role for cell-free, fluid-phase lymphatic trafficking during early alphavirus dissemination and that there may be tissue-specific signals that govern monocyte permissiveness to alphavirus infection. Our aim is to identify and define the mechanisms that drive monocyte heterogeneity in arthritogenic alphavirus infections. In a forthcoming manuscript (Holmes AC et al., submitted, PLoS Pathogens), we have identified a subset of platelet-derived growth factor alpha-positive (PDGFRα+) skeletal muscle mesenchymal cells that are infected via the major arthritogenic alphavirus entry receptor, matrix remodeling-associated protein 8 (MXRA8). Infection of this PDGFRα+ cell subset increases local vascular permeability to mediate virus spread directly to the bloodstream in a manner that is dependent on vascular endothelial growth factor (VEGF) signaling. Our aim is to define the molecular events that underlie the VEGF signaling cascade during arthritogenic alphavirus infections.
DUTIES
Duties will include:
- The candidate will be trained on and perform in vitro and in vivo experiments related to arthritogenic alphavirus infections
- The candidate will carry out qRT-PCR on mouse tissues
- The candidate will carry out flow cytometry
- The candidate will carry out microscopy and imaging of mouse tissues
- The candidate will generate and maintain primary cell lines from mice and commercially available cell lines and carry out arthritogenic alphavirus infections in both primary cells and cell lines
- The candidate will develop projects involving methods such as single-cell and spatial RNAseq
- The candidate will prepare manuscripts for publication
- The candidate will be required to work at both BSL-2 and BSL-3 and will receive the appropriate institutional safety training
We are a new lab supported by funding from the Howard Hughes Medical Institute (HHMI) and are looking to grow! The lab is committed to the success of all members and provides mentorship and opportunities for research and career development. We are located at the Jacobs School of Medicine and Biomedical Sciences in downtown Buffalo, NY.
BENEFITS
Working at UB comes with benefits that exceed salary alone. There are personal rewards including comprehensive health and retirement plan options. We also focus on creating and sustaining a healthy mix of work, personal and academic pursuit – all in an effort to support your work-life effectiveness. We support your growth and development through our career coaching and training department and we qualify as a public service loan forgiveness organization. Learn more about the great benefits the University at Buffalo has to offer.
MINIMUM QUALIFICATIONS
- PhD in Virology, Immunology, Microbiology, Molecular Biology, or a related field
- Expertise in some of the following areas: in vivo pathogenesis, flow cytometry, molecular virology, qPCR, confocal fluorescence microscopy, histology
- Highly motivated
- Possesses ability to work independently and collaboratively within a small team
- Time management and organizational skills
- Strong oral and written communication skills
- Mentorship experiences in the lab
PREFERRED QUALIFICATIONS
- Expertise in single-cell and/or spatial RNAseq and bioinformatics (not required but preferred)
- Expertise in live-animal imaging (not required but preferred)
PHYSICAL DEMANDS
DRIVING REQUIREMENTS
This position will never drive a university owned vehicle.
SALARY RANGE
$60,000 - $64,000
The salary range reflects our good faith and reasonable estimate of the possible compensation at the time of posting, the role and associated responsibilities, and the experience, education, and training of the selected candidate.
WORK HOURS
40
CAMPUS
Downtown Campus
BACKGROUND CHECK NOTIFICATION
Is a background check required for this posting? No
The Research Foundation of SUNY is an EOE and welcomes all to apply including veterans and individuals with a disability.
Senior Researcher Job Roles in New York
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Search Senior Researcher Jobs in New YorkSenior Researcher Jobs in New York: Frequently Asked Questions
Which companies sponsor visas for senior researchers in New York?
Pfizer, Memorial Sloan Kettering Cancer Center, IBM Research, Regeneron Pharmaceuticals, and Rockefeller University are among the most consistent sponsors of senior researcher roles in New York. Major research universities such as Columbia, Cornell, and NYU also file significant numbers of sponsorship petitions annually for research staff at the senior level.
Which visa types are most common for senior researcher roles in New York?
The H-1B visa is the most widely used visa for senior researchers in New York, as most roles require at least a master's degree in a specific scientific or technical field, meeting the specialty occupation requirement. Researchers with exceptional records of published work or awards may qualify for the O-1A. Academic and nonprofit research institutions can file H-1B petitions year-round outside the annual cap.
Which cities in New York have the most senior researcher sponsorship jobs?
New York City accounts for the largest concentration, driven by its density of hospitals, pharmaceutical companies, financial research firms, and universities. Tarrytown and the Hudson Valley corridor are significant for life sciences, anchored by Regeneron. Albany hosts state government research bodies and university research centers, while Buffalo and Rochester have growing academic research pipelines through SUNY and University of Rochester.
How to find senior researcher visa sponsorship jobs in New York?
Migrate Mate is a job board built specifically for international candidates seeking visa sponsorship in the U.S. You can filter by role and state to browse senior researcher positions in New York from employers with a documented history of sponsoring work visas. This makes it straightforward to identify relevant openings without sifting through listings from employers who do not sponsor.
Are there any New York-specific considerations for senior researcher visa sponsorship?
New York employers sponsoring H-1B workers must comply with Department of Labor prevailing wage requirements, which are benchmarked to local wage data and tend to reflect the high cost of living in New York City in particular. Senior researcher roles at nonprofits and universities benefit from cap-exempt H-1B status, allowing petitions to be filed at any time of year. New York State's concentration of NIH-funded research institutions also supports a strong pipeline for J-1 visa research exchange placements.
What is the prevailing wage for sponsored senior researcher jobs in New York?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.