Business Operations Manager Visa Sponsorship Jobs in Pennsylvania
Pennsylvania's business operations manager roles span Philadelphia's financial services and healthcare corridors, Pittsburgh's growing tech sector, and major employers like Comcast, UPMC, and PNC Financial. International candidates with backgrounds in process improvement, logistics coordination, or organizational strategy will find active sponsorship activity across the state's diverse industry base.
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THE POSITION
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.
At USM, we play a pivotal role in driving Genentech's mission to expand patient access to life-changing therapies. Our focus is on empowering healthcare stakeholders with the scientific evidence they need to make informed treatment decisions. By fostering deep collaborations across the dynamic healthcare ecosystem, we are committed to delivering better outcomes for patients while ensuring care remains accessible and affordable for all.
The Opportunity
The S&O Senior Manager orchestrates US Medical operations and capabilities. Reporting to the Head of Field Medical Excellence & Business Enablement, this role drives infrastructure and technology standards to ensure organizational excellence.
As a strategic execution partner, the manager translates the USM vision into field execution and operational discipline. The goal is to establish Field Medical as the premier scientific partner through a holistic customer experience.
Key Responsibilities
Drive Strategic Planning & Execution (The Enabler)
- Translate USM and Field Medical objectives into clear execution roadmaps and manage high-priority workstreams to ensure delivery and alignment.
Ensure Operational Rhythm & Effectiveness (The Orchestrator)
- Own the "Rhythm of USM" by embedding strategy into day-to-day execution, optimizing functional processes, and managing system evolution to ensure measurable outcomes and compliance.
Serve as a Strategic Thought Partner & Confidant
- Act as a trusted advisor by offering the "pulse" of USM, providing candid guidance, pressure-testing assumptions, and driving decisions through operational reality-checks.
Manage Cross-Functional Alignment (The Integrator)
- Serve as the strategic integrator, aligning work across functions (USM, DDA, Legal, Compliance, etc.), removing barriers, and acting as the communication conduit to ensure compliance and organizational transparency.
Who You Are
Qualifications & Experience
- Education: Bachelor’s degree.
- Professional Experience: Minimum of 5 years of work experience, including 3+ years in the pharmaceutical/biotech/healthcare industry or management consulting.
- Advisory Experience: Prior experience within a consulting firm or similarly fast-paced, client-focused environment, with demonstrated ability to manage complex priorities, provide strategic support, and operate with a high degree of professionalism and discretion.
- Execution Management: Proven track record in an operational or "pull-through" role, overseeing the maintenance of scalable capabilities or technology platforms.
- Fiscal Acumen: Proven experience managing departmental or project budgets, including forecasting and resource mapping.
- Technical Proficiency: Experience with project management tools and an understanding of AI/Machine Learning applications.
Preferred Experience
- MBA or related graduate-level/advanced degree.
- Launch excellence within the pharmaceutical or biotech industry experience, including cross-functional operational support of pre-launch through commercialization activities.
- 3+ years of experience in clinical development with strong skills in clinical trial data analysis and RWD.
- Certifications such as Six Sigma, PMP, or similar.
- Experience with Agile methodologies and a proven ability to embed products into existing workflows for impactful outcomes.
Location and Travel Requirements
- The role is field-based in either the Northeast and Southern regions, with a minimum of 30% of the time expected to be spent in the office in South San Francisco, CA, or traveling to locations designated by the Business.
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This role will be based in the Field (Northeast or Southern region).
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Preferred States of Residence
- AL, GA, FL, AR, LA, MS, KS, MO, KY, TN, VA, MI, OH, NC, SC, IN, IL, TX, OK, AZ, NM, PA, MD, NY, PA, WV, MA, CT, ME, RI, VT
The expected salary range for this position based on the primary location of South San Francisco, CA is $118,300.00 - 219,700.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are not available for this job posting.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
JOB FACTS
Job Sub Category Operations
Schedule Full time
Job Type Regular
Posted Date May 21st 2026
Job ID 202605-112709
Business Operations Manager Job Roles in Pennsylvania
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Search Business Operations Manager Jobs in PennsylvaniaBusiness Operations Manager Jobs in Pennsylvania: Frequently Asked Questions
Which companies sponsor visas for business operations managers in Pennsylvania?
Large Pennsylvania employers with documented H-1B visa sponsorship histories include Comcast, UPMC, PNC Financial, Vanguard, SAP America, and Johnson & Johnson's Pennsylvania operations. Mid-sized firms in logistics, healthcare administration, and financial services also sponsor regularly. Sponsorship activity is most concentrated in the Philadelphia metro and Pittsburgh, where corporate headquarters and regional offices drive the bulk of operations management hiring.
Which visa types are most common for business operations manager roles in Pennsylvania?
The H-1B is the most common visa category for business operations managers in Pennsylvania, provided the role requires a specialized bachelor's degree in a related field such as business administration, operations management, or industrial engineering. TN visas apply to Canadian and Mexican nationals in qualifying management categories. L-1A intracompany transferees moving into operations leadership roles at Pennsylvania offices of multinational firms represent another pathway employers use.
Which cities in Pennsylvania have the most business operations manager sponsorship jobs?
Philadelphia accounts for the largest share of business operations manager sponsorship activity in Pennsylvania, driven by its concentration of Fortune 500 companies, healthcare systems, and financial institutions. Pittsburgh follows, supported by growth in technology, healthcare, and professional services. Allentown, King of Prussia, and Malvern are secondary hubs, home to pharmaceutical and financial services firms that regularly hire operations managers at the sponsorship level.
How to find business operations manager visa sponsorship jobs in Pennsylvania?
Migrate Mate aggregates visa sponsorship jobs specifically for international candidates and lets you filter by role and state, making it straightforward to browse business operations manager openings across Pennsylvania. Because sponsorship-willing employers are filtered in by default, you avoid sifting through postings that don't apply to your situation. Focusing your search on Philadelphia and Pittsburgh employers in healthcare, financial services, and technology will return the most relevant results.
Are there state-specific factors that affect business operations manager sponsorship in Pennsylvania?
Pennsylvania's sponsoring employers must meet Department of Labor prevailing wage requirements specific to the Philadelphia or Pittsburgh metropolitan statistical areas, which differ from national averages. The state's strong university pipeline, including Wharton, Carnegie Mellon's Tepper School, and Penn State's Smeal College of Business, means employers are accustomed to sponsoring graduates from these programs. Operations roles tied to healthcare administration may also require familiarity with Pennsylvania-specific regulatory environments, which can influence how job requirements are framed.
What is the prevailing wage for sponsored business operations manager jobs in Pennsylvania?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.