Back End Developer Jobs in San Francisco, CA
Back End Developer jobs in San Francisco are concentrated in SoMa, the Financial District, and Mission Bay, with strong demand from fintech, enterprise software, and biotech employers. Companies hiring right now include ALTRUIST, E2B, and Quanata. Scan the live roles below and apply to whichever ones fit.
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What You'll Do
Design and implement scalable backend architecture for our memory platform
Build robust APIs that handle millions of memory retrievals per day
Optimize database performance and implement caching strategies
Collaborate with the engineering team on technical architecture decisions
Establish engineering best practices and code quality standards
Work with AI/ML teams to integrate memory retrieval algorithms
Monitor system performance and implement automated scaling solutions
What We're Looking For
5+ years of backend engineering experience
Strong proficiency in Python and modern web frameworks (FastAPI, Django, Flask)
Experience with PostgreSQL and database optimization
Knowledge of cloud platforms (AWS, GCP) and containerization (Docker, Kubernetes)
Understanding of caching systems (Redis, Memcached) and distributed architectures
Experience with API design and microservices architecture
Strong problem-solving skills and attention to detail
Experience with CI/CD pipelines and infrastructure as code
Nice to Have
Experience with AI/ML infrastructure and vector databases
Knowledge of similarity search and embedding systems
Background in high-performance computing or real-time systems
Previous startup or early-stage company experience
Open source contributions
Experience with monitoring tools (Prometheus, Grafana)
Knowledge of message queues (RabbitMQ, Apache Kafka)
See All 48 Back End Developer Jobs in San Francisco
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Find Back End Developer JobsBack End Developer Job Market in San Francisco
Who's Hiring
- ALTRUIST22

- E2B4E
- Quanata4

- You4

- Engramme4E
Top Industries Hiring
- Insurance
- Technology & Software
Back End Developer Jobs in San Francisco: Frequently Asked Questions
How do I get a back end developer job in San Francisco?
Target the sectors that hire most aggressively in San Francisco: fintech companies clustered in the Financial District, enterprise SaaS firms in SoMa, and biotech and health tech employers anchored around Mission Bay. Familiarity with distributed systems, cloud infrastructure on AWS or GCP, and API design gives candidates a clear edge here. Startups at the Series A and B stage are often the fastest to move from application to offer in this market.
Which companies hire back end developers in San Francisco?
Employers hiring back end developers in San Francisco right now include ALTRUIST, E2B, and Quanata, based on current listings on Migrate Mate as of November 2026. San Francisco's mix of late-stage startups, publicly traded tech firms, and financial institutions means openings range from small engineering teams building greenfield products to large organizations maintaining high-scale production systems.
Are there remote back end developer jobs in San Francisco?
Yes, and back end development is one of the more remote-compatible engineering roles since the work centers on code, APIs, and infrastructure rather than on-site hardware or lab access. About 74% of back end developer openings tied to San Francisco are remote or hybrid as of November 2026, with hybrid arrangements most common at fintech and enterprise SaaS companies that maintain offices in SoMa or the Financial District.
How can I get a back end developer job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is targeting early-stage startups in SoMa and Mission Bay, which often hire junior engineers who can grow quickly rather than waiting for a fully senior candidate. Associate software engineer and junior API developer roles are the most accessible entry points. Building a portfolio with deployed projects using Node.js, Python, or Go and contributing to open-source repositories strengthens an application significantly in this market.
Which industries hire the most back end developers in San Francisco?
The sectors hiring the most back end developers in San Francisco are Insurance and Technology & Software, based on current listings on Migrate Mate as of November 2026. San Francisco's role as a hub for fintech innovation, enterprise cloud software, and life sciences technology keeps demand for back end expertise concentrated in those fields year over year.
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