Operational Excellence Manager Jobs in California

The Position

Why Genentech

We’re passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly pursuing answers to the world’s most complex health challenges and transforming society.

Public Affairs & Access (PAA) is a multi-disciplinary organization that includes Corporate Communications; Policy, Evidence & Access Strategy; Channel & Contract Management; External Affairs; Patient Experience; and Strategy and Business Operations. Our purpose is to deliver impact through a fully integrated public affairs function that leverages our capabilities and world-class Genentech brand to deliver on our mission for patients and our employees.

The CMG Patient Strategy aims to create a holistic, cross-functional approach to deliver a best-in-class patient experience that aligns with the portfolio, technology tools, and consumer-driven patient expectations in a rapidly evolving business landscape.

The Opportunity

As the Senior Director, GPF Program Delivery and Operational Excellence, you will serve as a strategic leader accountable for the overarching direction, mid-term strategy, and operational execution of Genentech Patient Foundation (GPF, an independent, non-profit 501c3) programs. In this role, you will act as the primary decision-maker for Foundation operations, ensuring Frontline support services seamlessly enable product access and drug delivery for eligible patients across all therapeutic areas.

In this role, you can expect to:

• Lead and execute strategic GPF Board of Directors workstreams, architecting high-impact donor presentations in close partnership with the Head of GPF.

• Drive nationwide operational alignment to standardize the patient experience across multiple therapeutic areas through all product life cycle stages.

• Own the nationwide execution of new GPF programs, embedding Board-approved decisions into patient support services across all Genentech products.

• Spearhead strategic realignments of processes, SOPs, and systems to maximize operational efficiency while safeguarding GPF’s independent 501(c)(3) charitable status.

• Address highly complex patient cases, escalations, and exception requests, establishing structural changes to resolve systemic issues.

• Provide end-to-end oversight of a high-volume, high-value charitable product inventory, defining shipping and distribution standards that align with pharmaceutical regulations.

• Partner closely with PX Delivery Regional Leads, Marketing, and Customer Engagement leadership to integrate strategic insights into GPF operational planning.

Who you are

• You hold a Bachelor’s degree in a related field (e.g., business, finance, healthcare management, public policy) or equivalent experience (advanced degree preferred).

• You bring 12–15+ years of professional industry experience in healthcare, reimbursement, pharmaceuticals, biotechnology, or operations management.

• You have 5+ years of direct people management experience leading teams through change.

• You possess a proven track record of planning, prioritizing, and managing complex process changes and operational realignments.

• You exhibit strong influencing and communication skills, with a comfort in utilizing data and technology to improve patient outcomes.

Preferred

• Advanced degree (Master's, MBA, relevant PhD, or JD).

• Direct experience working with or supporting a 501(c)(3) charitable foundation or patient assistance program within the biopharmaceutical space.

• Deep expertise in pharmaceutical supply chain, inventory management, or drug distribution regulations.

Location

• This role is based in South San Francisco and offers a hybrid schedule working 3 days per week on campus.

• No relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of CA is $206,800 - $384,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.