Chief Of Staff Jobs in San Francisco, CA
Chief Of Staff jobs in San Francisco are in strong demand, concentrated in SoMa, the Financial District, and Mission Bay across technology, venture-backed startups, and healthcare. Employers hiring right now include ABHITO, MERCOR, and Lance. See the openings below and apply to the ones that match your experience.
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Showing 5 of 95+ Chief Of Staff jobs
Help lead Lance as it continues to scale.
About Lance
Lance (YC W26) builds autonomous AI agents that run hotel operations end to end. They answer guest calls and messages and coordinate the front desk, housekeeping and maintenance across hotel systems. We work with leading hotel groups across brands like Marriott, Hilton and Hyatt. We've gone from $0 to $2M+ ARR and are live at 50+ properties in the U.S. Our agents don't just assist. They execute. We work in person in San Francisco.
Total Compensation
$140K–$200K total compensation (cash, equity, bonus)
Role Overview
We're hiring a Chief of Staff to work directly with our CEO and help scale Lance. This is a high-ownership, execution-driven role across admin, legal, operations, compliance and finance. You'll take on the CEO's hardest problems and see them through.
What You'll Do
Be the CEO's right hand. Run the operating rhythm, prep for high-stakes meetings, and own special projects from investor updates to new initiatives.
Own operations and admin. Build the systems, policies and events that keep a fast-growing company running.
Run legal and compliance. Manage contracts and agreements, and keep SOC 2, ISO, HIPAA and PCI on track through enterprise security reviews.
Own finance and vendors. Run billing, payables, bookkeeping and insurance, and be the point of contact for vendors and partners.
Automate with AI. Turn one-off work into repeatable, automated processes wherever it saves time.
Drive cross-functional work. Lead projects across product, ops and go-to-market, and fill the gaps nobody else owns.
What We're Looking For
A degree from a strong school
A strong operator who takes initiative and loves owning things end to end
Management experience, and you want to manage and grow people
A builder of strong processes who thrives in ambiguity
Exceptional communication and sound judgment
Interest in AI automations and workflows
Preferred
A background in banking, a high-growth startup, management consulting or law
Why This Role
Work directly with the CEO and founders on core decisions
High ownership from day one, with room to build and lead a team
Exposure across the entire company at a company with real traction
Build real systems, not just decks
Benefits
Lunch provided
Health insurance: medical, dental and vision
Compensation Range: $140K - $200K
Help lead Lance as it continues to scale.
About Lance
Lance (YC W26) builds autonomous AI agents that run hotel operations end to end. They answer guest calls and messages and coordinate the front desk, housekeeping and maintenance across hotel systems. We work with leading hotel groups across brands like Marriott, Hilton and Hyatt. We've gone from $0 to $2M+ ARR and are live at 50+ properties in the U.S. Our agents don't just assist. They execute. We work in person in San Francisco.
Total Compensation
$140K–$200K total compensation (cash, equity, bonus)
Role Overview
We're hiring a Chief of Staff to work directly with our CEO and help scale Lance. This is a high-ownership, execution-driven role across admin, legal, operations, compliance and finance. You'll take on the CEO's hardest problems and see them through.
What You'll Do
Be the CEO's right hand. Run the operating rhythm, prep for high-stakes meetings, and own special projects from investor updates to new initiatives.
Own operations and admin. Build the systems, policies and events that keep a fast-growing company running.
Run legal and compliance. Manage contracts and agreements, and keep SOC 2, ISO, HIPAA and PCI on track through enterprise security reviews.
Own finance and vendors. Run billing, payables, bookkeeping and insurance, and be the point of contact for vendors and partners.
Automate with AI. Turn one-off work into repeatable, automated processes wherever it saves time.
Drive cross-functional work. Lead projects across product, ops and go-to-market, and fill the gaps nobody else owns.
What We're Looking For
A degree from a strong school
A strong operator who takes initiative and loves owning things end to end
Management experience, and you want to manage and grow people
A builder of strong processes who thrives in ambiguity
Exceptional communication and sound judgment
Interest in AI automations and workflows
Preferred
A background in banking, a high-growth startup, management consulting or law
Why This Role
Work directly with the CEO and founders on core decisions
High ownership from day one, with room to build and lead a team
Exposure across the entire company at a company with real traction
Build real systems, not just decks
Benefits
Lunch provided
Health insurance: medical, dental and vision
Compensation Range: $140K - $200K
See All 95 Chief Of Staff Jobs in San Francisco
Find roles in San Francisco that match your experience and apply in just a few clicks.
Find Chief Of Staff JobsChief Of Staff Job Market in San Francisco
Who's Hiring
- ABHITO12A
- MERCOR6
- Lance3
- CRUSOE3
- sphinx3
Top Industries Hiring
- Technology & Software
- Banking & Financial Services
Chief Of Staff Jobs in San Francisco: Frequently Asked Questions
How do I get a chief of staff job in San Francisco?
Target San Francisco's high-growth technology companies, venture capital-backed startups in SoMa and Mission Bay, and large healthcare systems like UCSF Health. Candidates who can move fluidly between strategic planning, cross-functional coordination, and executive communication stand out. Prior experience inside a fast-scaling startup or a large tech organization gives you a concrete edge over generalist applicants in this market.
Which companies hire chief of staffs in San Francisco?
Companies currently hiring chief of staffs in San Francisco include ABHITO, MERCOR, and Lance, per current listings on Migrate Mate as of November 2026. San Francisco's employer base skews toward technology companies, growth-stage startups, and major healthcare and financial services institutions, all of which frequently build out chief of staff functions as they scale.
Are there remote chief of staff jobs in San Francisco?
Yes, though chief of staff roles are less remote-friendly than purely analytical positions because the job centers on in-person executive support and cross-team coordination. About 65% of chief of staff openings tied to San Francisco are remote or hybrid as of November 2026, with the most remote-compatible work being research, reporting, and project management tasks rather than day-to-day executive presence.
How can I get a chief of staff job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is moving laterally from a chief of staff associate, executive business partner, or strategy and operations analyst role inside a local tech company or health system. Growth-stage startups in SoMa and the Financial District often promote from within, and rotational operations programs at larger San Francisco employers like Salesforce or Wells Fargo can build the cross-functional exposure hiring managers look for.
Which industries hire the most chief of staffs in San Francisco?
San Francisco chief of staff roles concentrate in Technology & Software and Banking & Financial Services, based on current listings on Migrate Mate as of November 2026. San Francisco's density of venture-funded technology companies, large financial services firms, and major academic medical centers creates consistent demand for chiefs of staff who can manage complex, fast-moving executive agendas.
Related Jobs in California
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