Clinical Nurse Jobs in Pittsburgh, PA
Clinical Nurse jobs in Pittsburgh are concentrated across the Oakland medical corridor, Uptown, and the North Shore, with strong demand in acute care, critical care, and outpatient settings from employers like UPMC, University of Pittsburgh, and Duquesne University. Pittsburgh's density of academic medical centers and regional health systems keeps hiring active year-round. See the openings below and apply to the ones that match your experience.
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This position is for the Division of Endocrinology within the Department of Pediatrics. We are seeking an enthusiastic RN to join our type 1 diabetes (T1D) clinical research team. The primary focus of this position is recruiting participants into our multiple type 1 diabetes research study protocols. Blood draw experience is preferred. The incumbent will be responsible for recruiting participants into the study, conducting blood draws and sample collections from IV lines, talking with potential participants about the studies, research testing results, as well as conducting visits. Strong verbal and written communication skills are required. Research visits take place at UPMC Children’s Hospital of Pittsburgh (CHP) in Lawrenceville, at CHP satellite locations, and at various outreach locations and T1D events, some of which occur on evenings and weekends. The incumbent must be willing to travel. If not utilizing public transportation for travel, a valid driver’s license is required. It is the expectation that the incumbent will use their own vehicle required for local travel and the owner of the vehicle must carry automobile liability insurance. The owner’s automobile liability insurance coverage is primary coverage. The University’s automobile liability insurance policy provides excess coverage only. Equivalent relevant work experience may be substituted for degree requirement. This position is located at UPMC Children’s Hospital of Pittsburgh in Lawrenceville. PA Child Abuse History Clearance, PA State Police Criminal Record Check, and FBI Criminal Record Check will be required prior to the start of employment. Also, a current TB test will be required as a condition of employment.
Job Summary
Supports clinical research projects by coordinating projects and drug trials, assessing patients' qualifications, and facilitating protocols. Collects and reviews lab results, patient data, and lab specimens; administers medications and protocol-specific treatments. Performs general laboratory duties and specialized nursing duties, trains new staff, and ensures regulatory adherence.
This position will support the clinical research team by participating in an increasing number of ongoing, funded type 1 diabetes research studies.
- Coordinates clinical research projects and drug trials. Assesses patients for qualification/enrollment in research projects and subject groups. Implements research protocols. Monitors patient assessments.
- Collects and reviews lab results; monitors results for adverse reactions.
- Collects patient data, including medical histories and physical assessments. Maintains and enters data into databases/logs in a timely and accurate manner.
- Performs general laboratory duties including, but not limited to, monitors supply inventory, monitors temperatures of freezers and refrigerators, cleans equipment, and disposes of biological waste. Performs specialized nursing duties such as arterial puncture, venipuncture, and operation of electronic monitoring equipment; assists with surgical and/or invasive procedures.
- Administers treatment and/or medication in accordance with research protocol.
- Collects, prepares, and processes lab specimens.
- Ensures all protocol and regulatory standards adherence.
- Participates in the development of internal review board submissions as requested.
- Collaborates with multiple investigators, sponsors, and research coordinators.
- Assists with training of new staff and ongoing guidance of newer staff.
Light to medium.
The University of Pittsburgh is an equal opportunity employer / disability / veteran.
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Find Clinical Nurse JobsClinical Nurse Job Market in Pittsburgh
Who's Hiring
- UPMC56

- University of Pittsburgh37

- Duquesne University19

- Momentum Life Sciences19

- Allegheny Health Network19

Top Industries Hiring
- Healthcare & Medical Services
Clinical Nurse Jobs in Pittsburgh: Frequently Asked Questions
How do I get a clinical nurse job in Pittsburgh?
Target Pittsburgh's major health systems anchored in Oakland, Uptown, and the South Side, where acute care, surgical, and emergency departments hire most consistently. Community hospitals in the surrounding suburbs of Bethel Park, Monroeville, and Wexford also post regularly. Candidates with ICU, med-surg, or oncology experience move fastest through Pittsburgh hiring pipelines, and BSN-prepared nurses with clinical rotation experience at local facilities tend to get priority screening.
Which companies hire clinical nurses in Pittsburgh?
Employers hiring clinical nurses in Pittsburgh right now include UPMC, University of Pittsburgh, and Duquesne University, based on current listings on Migrate Mate as of November 2026. Pittsburgh's clinical nurse market is dominated by large academic health systems and regional hospital networks, with additional openings at long-term care facilities, outpatient specialty clinics, and federally qualified health centers serving neighborhoods like Homewood and the Hill District.
How can I get a clinical nurse job in Pittsburgh with little or no experience?
The most realistic entry path in Pittsburgh is a new-graduate residency program, which the major Oakland-based academic medical centers and regional health systems run on a rolling or cohort basis. Positions in long-term care facilities and rehabilitation centers across the greater Pittsburgh area are also more accessible for nurses with limited acute-care hours. Completing clinical rotations at Pittsburgh institutions, obtaining BLS and ACLS certification before applying, and targeting med-surg units as a stepping stone into specialty floors all strengthen a new-grad application locally.
Which industries hire the most clinical nurses in Pittsburgh?
The sectors hiring the most clinical nurses in Pittsburgh are Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. Pittsburgh's economy is anchored by world-class academic medicine and a growing network of outpatient and specialty care facilities, which together sustain consistent clinical nurse demand across inpatient, ambulatory, and home-health settings.
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