Clinical Operations Director Jobs in New Jersey
Clinical Operations Director jobs in New Jersey draw steady demand from one of the most active life sciences and healthcare markets in the country, with openings concentrated in pharmaceutical research, hospital systems, and contract research organizations at every level from newly promoted director through senior executive. The heaviest hiring runs through Newark, Princeton, and the Route 1 corridor, where established employers like Johnson & Johnson, Hackensack Meridian Health, and RWJBarnabas Health maintain large clinical operations footprints. The most sought-after specialties include oncology trial management, regulatory affairs integration, and multi-site hospital operations. Find a role that fits below and apply directly.
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Showing 5 of 9+ Clinical Operations Director jobs
About Summit:
Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit's core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.
Summit's team is inspired to touch and help change lives through Summit's clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:
Non-small Cell Lung Cancer (NSCLC)
HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.
HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.
Colorectal Cancer (CRC)
HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.
Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China's National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.
ASSOCIATE DIRECTOR, CLINICAL OPERATIONS
Location: Princeton, NJ or Miami, FL ONSITE
Overview of Role:
The Associate Director, Clinical Operations provides operational leadership for clinical trial execution, overseeing the clinical operations team and vendor performance. This role ensures effective study delivery through cross functional collaboration, proactive risk management, and strong execution oversight. This role leads vendor strategy and oversight ensuring external partners deliver against scope, timelines, quality expectations, and operational objectives.
The ideal candidate thrives in a fast-paced, entrepreneurial environment, demonstrates exceptional operational leadership, and possesses strong business acumen with an understanding of the competitive landscape, capital allocation, and value creation throughout drug development.
Role and Responsibilities:
- Oversees the clinical operational strategy, planning, and execution of one or more global clinical trials.
- Ensures internal clinical and external teams deliver on time, within budget and in compliance with GCP, ICH guidelines, applicable regulations and are always inspection-ready.
- Drafts, reviews and approves internal and external study-related plans, processes, and documents including Informed Consent Forms, Investigator Agreements (CTA), CRFs, CRF Guidelines, statistical/pharmacokinetic analysis plans, monitoring plans, data management plans, and safety monitoring activities.
- Manages CROs, vendors, and strategic partners through robust governance, performance metrics, and risk management.
- Identifies operational risks early and implement proactive mitigation strategies escalating to leadership.
- Drives financial accountability through effective budget management and resource utilization.
- Oversees maintenance, quality, and completeness of the Trial Master File (TMF) and ensures all TMF quality reviews are completed.
- Manages CRO proposals, vendor contracts/change orders, and outsourcing strategies ensuring delivery with a focus on value and return on investment.
- Partners with Finance to provide oversight of vendors costs, supporting prudent operational decisions that align with budgets and financial plans.
- Oversees preparations for regulatory inspections, supports inspection management activities, and ensures the project is always inspection-ready.
- Manages, mentors and provides guidance to CTMs, CRAs, and other Clinical Operations team members.
- Drives continuous improvement initiatives and contributes to development of Clinical Operations processes and standards.
- Represents Clinical Operations on cross-functional study teams and governance meetings.
- Fosters collaboration with external partners, Regulatory Affairs, Clinical Science, Data Management, Biostatistics, Pharmacovigilance, Quality Assurance, CMC, and Commercial teams.
- All other duties as assigned
Experience, Education and Specialized Knowledge and Skills:
- Bachelor's degree or equivalent in life science, nursing, pharmacy, medical laboratory technology, or other health/medical-related areas
- 10+ years of direct clinical trial management experience overseeing phase II/III international oncology clinical trials
- Ability to travel internationally to visit clinical sites and study meetings. Amount will vary upon project needs (up to 20%)
Preferred Experience, Education and Specialized Knowledge and Skills:
- Consistently demonstrates ability to solve problems and use clear judgment in relation to regulatory requirements, interactions with external parties, timelines, and complex clinical programs
- Excellent planning, leadership, communication, negotiation, and organizational skills when working with both internal and external teams.
- Expert knowledge of the drug development process, ICH guidelines/GCP with a deep understanding of all phases of clinical trial execution and the ability to apply this knowledge to complex, global studies.
Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.
Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit's Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.
Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
About Summit:
Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit's core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.
Summit's team is inspired to touch and help change lives through Summit's clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:
Non-small Cell Lung Cancer (NSCLC)
HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.
HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.
Colorectal Cancer (CRC)
HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.
Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China's National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.
ASSOCIATE DIRECTOR, CLINICAL OPERATIONS
Location: Princeton, NJ or Miami, FL ONSITE
Overview of Role:
The Associate Director, Clinical Operations provides operational leadership for clinical trial execution, overseeing the clinical operations team and vendor performance. This role ensures effective study delivery through cross functional collaboration, proactive risk management, and strong execution oversight. This role leads vendor strategy and oversight ensuring external partners deliver against scope, timelines, quality expectations, and operational objectives.
The ideal candidate thrives in a fast-paced, entrepreneurial environment, demonstrates exceptional operational leadership, and possesses strong business acumen with an understanding of the competitive landscape, capital allocation, and value creation throughout drug development.
Role and Responsibilities:
- Oversees the clinical operational strategy, planning, and execution of one or more global clinical trials.
- Ensures internal clinical and external teams deliver on time, within budget and in compliance with GCP, ICH guidelines, applicable regulations and are always inspection-ready.
- Drafts, reviews and approves internal and external study-related plans, processes, and documents including Informed Consent Forms, Investigator Agreements (CTA), CRFs, CRF Guidelines, statistical/pharmacokinetic analysis plans, monitoring plans, data management plans, and safety monitoring activities.
- Manages CROs, vendors, and strategic partners through robust governance, performance metrics, and risk management.
- Identifies operational risks early and implement proactive mitigation strategies escalating to leadership.
- Drives financial accountability through effective budget management and resource utilization.
- Oversees maintenance, quality, and completeness of the Trial Master File (TMF) and ensures all TMF quality reviews are completed.
- Manages CRO proposals, vendor contracts/change orders, and outsourcing strategies ensuring delivery with a focus on value and return on investment.
- Partners with Finance to provide oversight of vendors costs, supporting prudent operational decisions that align with budgets and financial plans.
- Oversees preparations for regulatory inspections, supports inspection management activities, and ensures the project is always inspection-ready.
- Manages, mentors and provides guidance to CTMs, CRAs, and other Clinical Operations team members.
- Drives continuous improvement initiatives and contributes to development of Clinical Operations processes and standards.
- Represents Clinical Operations on cross-functional study teams and governance meetings.
- Fosters collaboration with external partners, Regulatory Affairs, Clinical Science, Data Management, Biostatistics, Pharmacovigilance, Quality Assurance, CMC, and Commercial teams.
- All other duties as assigned
Experience, Education and Specialized Knowledge and Skills:
- Bachelor's degree or equivalent in life science, nursing, pharmacy, medical laboratory technology, or other health/medical-related areas
- 10+ years of direct clinical trial management experience overseeing phase II/III international oncology clinical trials
- Ability to travel internationally to visit clinical sites and study meetings. Amount will vary upon project needs (up to 20%)
Preferred Experience, Education and Specialized Knowledge and Skills:
- Consistently demonstrates ability to solve problems and use clear judgment in relation to regulatory requirements, interactions with external parties, timelines, and complex clinical programs
- Excellent planning, leadership, communication, negotiation, and organizational skills when working with both internal and external teams.
- Expert knowledge of the drug development process, ICH guidelines/GCP with a deep understanding of all phases of clinical trial execution and the ability to apply this knowledge to complex, global studies.
Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.
Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit's Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.
Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
See All 9 Clinical Operations Director Jobs in New Jersey
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Find JobsClinical Operations Director Jobs by City in New Jersey
Where New Jersey roles are concentrated, by current openings.
Clinical Operations Director Job Market in New Jersey
A snapshot from current New Jersey openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Healthcare & Medical Services
What New Jersey Employers Look For
The qualifications that appear most often in clinical operations director jobs across New Jersey.
- Bachelor's degree in health sciences, nursing, or a related clinical field required
- Minimum seven years of progressive clinical operations or healthcare management experience
- Demonstrated leadership of cross-functional clinical teams across multiple sites or departments
- Proficiency with clinical trial management systems or electronic health record platforms
- Strong knowledge of FDA regulations, GCP guidelines, and healthcare compliance standards
- Master's degree in health administration, public health, or business administration preferred
Clinical Operations Director Jobs in New Jersey: Frequently Asked Questions
How do you become a clinical operations director in New Jersey?
Most clinical operations directors in New Jersey come up through clinical or research roles before moving into management. New Jersey does not require a state-issued director license for this role, but employers in hospital systems and pharmaceutical organizations typically expect a graduate degree in health administration, nursing leadership, or a related field. Building experience within New Jersey's dense life sciences corridor along Route 1 or within a large health system accelerates the path considerably.
Which companies hire clinical operations directors in New Jersey?
Employers hiring clinical operations directors in New Jersey right now include Daiichi Sankyo, IQVIA, and Atlantic Health, based on current listings on Migrate Mate as of August 2026. New Jersey's concentration of major pharmaceutical headquarters and large regional health systems means that openings appear year-round rather than in bursts tied to a single hiring season.
Which New Jersey cities have the most clinical operations director jobs?
Basking Ridge, New Jersey, and Wall account for the most clinical operations director openings in New Jersey. The concentration around Newark reflects the city's large hospital networks and academic medical centers, while the Princeton and Route 1 corridor draws heavily from the pharmaceutical and contract research organizations headquartered throughout that region.
Are there remote clinical operations director jobs in New Jersey?
Yes, but they are limited. Clinical operations directors typically oversee staff, facilities, and active trials that require regular on-site presence. About 25% of clinical operations director openings tied to New Jersey are remote or hybrid as of August 2026, and when flexibility does exist it tends to apply to the administrative, reporting, and strategic planning portions of the role rather than direct oversight functions.
How can I get hired as a clinical operations director in New Jersey with little or no experience?
The most realistic entry path is through a clinical coordinator or operations manager role within one of New Jersey's large health systems, such as RWJBarnabas Health or Hackensack Meridian Health, both of which run structured leadership development programs. Lateral moves from roles like clinical project manager, quality assurance manager, or regulatory affairs specialist are common stepping stones. Earning a Certified Associate in Project Management credential or completing a health administration graduate program strengthens a candidate's profile significantly for internal promotion.
Where can I find and apply to clinical operations director jobs in New Jersey?
You can find and apply to clinical operations director jobs in New Jersey on Migrate Mate, which lists current openings from employers across the state. Find roles that fit your experience and apply directly from each listing without any additional steps in between.
See All 9 Clinical Operations Director Jobs in New Jersey
Find roles in New Jersey that match your experience and apply in just a few clicks.
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