Senior Level Clinical Research Nurse Jobs

Senior level clinical research nurse jobs place experienced nurses in charge of protocol oversight, site coordination, and the clinical teams and investigators executing complex trials. Roles are concentrated in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Education, with a mix of on-site, remote, and hybrid settings, and employers like Jobot, Colgate-Palmolive, and Guthrie hiring at this level now.

Find Jobs

Overview

Open roles24
Top stateFlorida
Top employerJobot
Top cityHollywood, FL
Work type56% On-site
Top industryHealthcare

Showing 5 of 24+ Senior Level Clinical Research Nurse jobs

Director - Clinical Research Quality Assurance
We won't show you this job again
Added 2w ago
Director - Clinical Research Quality Assurance
Memorial Healthcare System
Hollywood, Florida
Clinical Trials & Medical Research
Healthcare Administration
Clinical Trials
On-Site
Bachelor's

Have you applied for this role?

Manager, Clinical Research - Ophthalmology & Visual Sciences
We won't show you this job again
Added 1mo ago
Manager, Clinical Research - Ophthalmology & Visual Sciences
Medical College of Wisconsin
Milwaukee, Wisconsin
Program Management
Project Management
Quality Assurance & Testing (QA Testing)
Master's degree
5,001-10,000

Have you applied for this role?

Clinical Research Physician
We won't show you this job again
Added 1mo ago
Clinical Research Physician
Epic Medical Research
DeSoto, Texas
Nursing
Healthcare Administration
Clinical Support
Medical Specialists
$200k - $240k/yr
On-Site
Doctorate

Have you applied for this role?

Vice President, Emory Clinical Research Office (ECRO)
We won't show you this job again
Added 1mo ago
Vice President, Emory Clinical Research Office (ECRO)
Emory University
Atlanta, Georgia
Executive Leadership & C-Suite
Program Management
Project Management
Remote (US)
Master's degree in health science
10,000+

Have you applied for this role?

Senior Clinical Research Associate
We won't show you this job again
Added 2mo ago
Senior Clinical Research Associate
ImmunityBio
Remote
Clinical Trials & Medical Research
Healthcare Administration
Laboratory Research
Clinical Trials
$133k - $140k/yr
Remote (US)
Bachelor's
201-500

Have you applied for this role?

See All 24 Senior Level Clinical Research Nurse Jobs

Find roles that match your experience and apply in just a few clicks.

Find Jobs

Senior Level Clinical Research Nurse Job Market

Who's Hiring

Jobot4 open roles
Colgate-Palmolive2 open roles
Guthrie1 open role

Top Industries Hiring

  • Healthcare & Medical Services
  • Biotechnology & Pharmaceuticals
  • Education
  • Staffing & Recruiting
  • Chemicals & Materials

Senior Level Clinical Research Nurse Jobs: Frequently Asked Questions

How do I get a senior level clinical research nurse job?

Employers hiring at this level look for nurses who have led trial execution from site initiation through closeout, not just supported it. Holding a CCRC or CCRP credential signals that depth. Experience managing regulatory submissions, training junior staff, and serving as the primary contact for sponsors or IRBs puts a candidate well ahead of the field at the senior stage.

Which companies hire senior level clinical research nurses?

Companies hiring senior level clinical research nurses right now include Jobot, Colgate-Palmolive, and Guthrie, based on current listings on Migrate Mate as of October 2026. Hiring at this level comes primarily from large academic medical centers, contract research organizations, and pharmaceutical or biotech companies running Phase II through Phase IV trials.

Are there remote senior level clinical research nurse jobs?

Yes, though most senior roles still involve some on-site or travel component tied to site monitoring and investigator oversight. About 44% of senior level clinical research nurse openings are remote or hybrid as of October 2026, with fully remote positions most common in study coordination, regulatory affairs support, and protocol review roles at larger sponsors and CROs.

What makes a clinical research nurse role senior level?

Senior level roles carry ownership over trial operations rather than task execution. That means leading site management across multiple protocols, authoring or reviewing regulatory documents, mentoring coordinators and junior nurses, and serving as the clinical point of accountability for sponsors, IRBs, and investigators. The scope is broader and the decisions carry more downstream consequence than in mid-level positions.

Which industries hire the most senior level clinical research nurses?

Senior level clinical research nurse roles concentrate in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Education, based on current listings on Migrate Mate as of October 2026. These sectors drive hiring at this level because they run the largest trial portfolios, require experienced clinical oversight to satisfy regulatory standards, and need nurses who can lead teams through complex multi-site studies.