Senior Level Clinical Research Nurse Jobs
Senior level clinical research nurse jobs place experienced nurses in charge of protocol oversight, site coordination, and the clinical teams and investigators executing complex trials. Roles are concentrated in Education, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, with a mix of on-site, remote, and hybrid settings, and employers like Jobot, Colgate-Palmolive, and Cambridge Pharma Consulting hiring at this level now.
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The University of Alabama at Birmingham (UAB), Family & Community Medicine Chair Office, is seeking a Manager-Clinical Research Administration.
The Clinical Research Administration Manager will play a pivotal role in overseeing all aspects of clinical trial operations within the Department of Family and Community Medicine at UAB. This position is responsible for managing a team of clinical coordinators, ensuring compliance with regulatory requirements, and fostering collaboration with internal and external research sites. The ideal candidate will demonstrate strong leadership, organizational, and communication skills, with a proven track record in clinical research management.
General Responsibilities
To act as a subject matter expert (SME) for faculty and staff regarding administrative duties for industry and sponsored clinical research.
To serve as a referral resource for the clinical research community at UAB.
To manage and maintain the study s compliance with institutional requirements.
To manage division-wide training in ethical conduct of research.
To manage, assess and determine solutions for operational shortcomings of protocols.
To provide human resources oversight for subordinate personnel.
Key Duties & Responsibilities
Manages and supervises clinical research coordinators and research staff, including all applicable human resource functions, across multiple ongoing and upcoming clinical trials.
Prepares, submits, and maintains regulatory documentation, including IRB submissions, amendments, and continuing reviews, while supporting broader regulatory compliance activities as needed.
Leads and coordinates study activation, site initiation, ongoing management, and study closeout activities across multiple clinical research protocols.
Monitors study progress and staff activities to ensure adherence to study protocols, timelines, budgets, and all clinical and regulatory requirements.
Develops protocol-specific systems and study documentation, including process flows, training materials, CRFs, and other operational tools.
Prepares and manages study budgets, and collaborates with investigators and sponsors on financial planning and execution.
Provides training, mentorship, and professional development for research staff, including assigning responsibilities, reviewing work, and identifying process improvements.
Coordinates communication with internal teams, investigators, sponsors, and external research sites to ensure efficient trial operations and data integrity.
Develops and implements recruitment and retention strategies to support successful study enrollment and completion.
Ensures compliance with all applicable federal, state, and institutional regulations and guidelines (e.g., FDA, IRB, GCP).
Collaborates with investigators, sponsors, and other stakeholders to support successful trial execution.
Performs other duties as assigned.
Annual Salary Range: $77,640 - $126,170
Bachelor's degree in a related field and eight (8) years of related experience required. Work experience may NOT substitute for education requirement. Certified Clinical Research Coordinator (CCRC) or Certified Clinical Research Professional (CCRP) certification strongly preferred.
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
The University of Alabama at Birmingham (UAB), Family & Community Medicine Chair Office, is seeking a Manager-Clinical Research Administration.
The Clinical Research Administration Manager will play a pivotal role in overseeing all aspects of clinical trial operations within the Department of Family and Community Medicine at UAB. This position is responsible for managing a team of clinical coordinators, ensuring compliance with regulatory requirements, and fostering collaboration with internal and external research sites. The ideal candidate will demonstrate strong leadership, organizational, and communication skills, with a proven track record in clinical research management.
General Responsibilities
To act as a subject matter expert (SME) for faculty and staff regarding administrative duties for industry and sponsored clinical research.
To serve as a referral resource for the clinical research community at UAB.
To manage and maintain the study s compliance with institutional requirements.
To manage division-wide training in ethical conduct of research.
To manage, assess and determine solutions for operational shortcomings of protocols.
To provide human resources oversight for subordinate personnel.
Key Duties & Responsibilities
Manages and supervises clinical research coordinators and research staff, including all applicable human resource functions, across multiple ongoing and upcoming clinical trials.
Prepares, submits, and maintains regulatory documentation, including IRB submissions, amendments, and continuing reviews, while supporting broader regulatory compliance activities as needed.
Leads and coordinates study activation, site initiation, ongoing management, and study closeout activities across multiple clinical research protocols.
Monitors study progress and staff activities to ensure adherence to study protocols, timelines, budgets, and all clinical and regulatory requirements.
Develops protocol-specific systems and study documentation, including process flows, training materials, CRFs, and other operational tools.
Prepares and manages study budgets, and collaborates with investigators and sponsors on financial planning and execution.
Provides training, mentorship, and professional development for research staff, including assigning responsibilities, reviewing work, and identifying process improvements.
Coordinates communication with internal teams, investigators, sponsors, and external research sites to ensure efficient trial operations and data integrity.
Develops and implements recruitment and retention strategies to support successful study enrollment and completion.
Ensures compliance with all applicable federal, state, and institutional regulations and guidelines (e.g., FDA, IRB, GCP).
Collaborates with investigators, sponsors, and other stakeholders to support successful trial execution.
Performs other duties as assigned.
Annual Salary Range: $77,640 - $126,170
Bachelor's degree in a related field and eight (8) years of related experience required. Work experience may NOT substitute for education requirement. Certified Clinical Research Coordinator (CCRC) or Certified Clinical Research Professional (CCRP) certification strongly preferred.
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
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Senior Level Clinical Research Nurse Jobs: Frequently Asked Questions
How do I get a senior level clinical research nurse job?
Employers hiring at this level look for nurses who have led trial execution from site initiation through closeout, not just supported it. Holding a CCRC or CCRP credential signals that depth. Experience managing regulatory submissions, training junior staff, and serving as the primary contact for sponsors or IRBs puts a candidate well ahead of the field at the senior stage.
Which companies hire senior level clinical research nurses?
Companies hiring senior level clinical research nurses right now include Jobot, Colgate-Palmolive, and Cambridge Pharma Consulting, based on current listings on Migrate Mate as of August 2026. Hiring at this level comes primarily from large academic medical centers, contract research organizations, and pharmaceutical or biotech companies running Phase II through Phase IV trials.
Are there remote senior level clinical research nurse jobs?
Yes, though most senior roles still involve some on-site or travel component tied to site monitoring and investigator oversight. About 42% of senior level clinical research nurse openings are remote or hybrid as of August 2026, with fully remote positions most common in study coordination, regulatory affairs support, and protocol review roles at larger sponsors and CROs.
What makes a clinical research nurse role senior level?
Senior level roles carry ownership over trial operations rather than task execution. That means leading site management across multiple protocols, authoring or reviewing regulatory documents, mentoring coordinators and junior nurses, and serving as the clinical point of accountability for sponsors, IRBs, and investigators. The scope is broader and the decisions carry more downstream consequence than in mid-level positions.
Which industries hire the most senior level clinical research nurses?
Senior level clinical research nurse roles concentrate in Education, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of August 2026. These sectors drive hiring at this level because they run the largest trial portfolios, require experienced clinical oversight to satisfy regulatory standards, and need nurses who can lead teams through complex multi-site studies.