Senior Level Clinical Research Nurse Jobs
Senior level clinical research nurse jobs place experienced nurses in charge of protocol oversight, site coordination, and the clinical teams and investigators executing complex trials. Roles are concentrated in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Education, with a mix of on-site, remote, and hybrid settings, and employers like Jobot, Colgate-Palmolive, and Guthrie hiring at this level now.
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Location: Hollywood, Florida
At Memorial, we are dedicated to improving the health, well-being and, most of all, quality of life for the people entrusted to our care. An unwavering commitment to our service vision is what makes the difference. It is the foundation of The Memorial Experience.
Summary
The Clinical Research Quality Assurance Director provides strategic and operational oversight of the institution’s clinical research quality assurance program, ensuring compliance with federal regulations, Good Clinical Practice (GCP), institutional policies, sponsor requirements, and human research protection standards. This role leads proactive quality and monitoring initiatives, drives continuous improvement, and partners with investigators, research leadership, compliance, IRB, and operational teams to promote research integrity, participant safety, and audit readiness.
Responsibilities
- Serves as a key institutional resource during audits, inspections, and accreditation activities, ensuring timely follow-up, risk mitigation, and resolution of findings.
- Leads and oversees the enterprise clinical research quality assurance and monitoring program, including routine, for-cause, and risk-based reviews.
- Develops, implements, and maintains QA policies, SOPs, corrective and preventive action (CAPA) processes, and quality improvement initiatives aligned with regulatory and accreditation standards.
- Monitors evolving federal, state, sponsor, and accreditation requirements such as ICH-GCP E6 updates and ensures timely integration into institutional policies, workflows, and practices.
- Provides training, education and strategic guidance to investigators, research staff, and leadership on GCP, FDA, OHRP, HIPAA, and institutional compliance requirements.
Competencies
- Business Acumen
- Concern for Quality
- Develop Relationships
- Lead Through Vision
- Manage Performance
Education And Certification Requirements
Bachelors (Required)
Additional Job Information
Complexity of Work: Requires critical thinking skills, effective communication skills, organization skills, decisive judgment and the ability to work with minimal supervision. Must be able to work in a stressful environment and take appropriate action. In-depth knowledge of federal regulations governing human subjects’ research. Demonstrated expertise in FDA regulations, OHRP requirements, ICH-GCP guidelines, HIPAA/privacy regulations, and clinical research quality systems.
Required Work Experience:
A minimum of eight (8) years of progressive core experience in clinical research, human research protections, research compliance, quality assurance, auditing, or related research administration functions, including at least four (4) years in a leadership or managerial capacity. Prior leadership or management experience overseeing quality assurance, compliance, monitoring, or research operations within an academic medical center, health system, CRO, sponsor, or research institution preferred.
Other Information:
Additional Education Info: Bachelor’s degree in Healthcare, Nursing, Science, Public Health or a related field. Master’s degree in a related field preferred. Relevant professional certification(s) such as CCRC, CCRP, CHRC, CIP, or equivalent preferred.
Working Conditions And Physical Requirements
- Bending and Stooping = 0%
- Climbing = 0%
- Keyboard Entry = 80%
- Kneeling = 0%
- Lifting/Carrying Patients 35 Pounds or Greater = 0%
- Lifting or Carrying 0 - 25 lbs Non-Patient = 0%
- Lifting or Carrying 2501 lbs - 75 lbs Non-Patient = 0%
- Lifting or Carrying > 75 lbs Non-Patient = 0%
- Pushing or Pulling 0 - 25 lbs Non-Patient = 0%
- Pushing or Pulling 26 - 75 lbs Non-Patient = 0%
- Pushing or Pulling > 75 lbs Non-Patient = 0%
- Reaching = 0%
- Repetitive Movement Foot/Leg = 0%
- Repetitive Movement Hand/Arm = 80%
- Running = 0%
- Sitting = 80%
- Squatting = 0%
- Standing = 80%
- Walking = 80%
- Audible Speech = 80%
- Hearing Acuity = 80%
- Smelling Acuity = 0%
- Taste Discrimination = 0%
- Depth Perception = 80%
- Distinguish Color = 80%
- Seeing - Far = 80%
- Seeing - Near = 80%
- Bio hazardous Waste = 0%
- Biological Hazards - Respiratory = 0%
- Biological Hazards - Skin or Ingestion = 0%
- Blood and/or Bodily Fluids = 0%
- Communicable Diseases and/or Pathogens = 0%
- Asbestos = 0%
- Cytotoxic Chemicals = 0%
- Dust = 0%
- Gas/Vapors/Fumes = 0%
- Hazardous Chemicals = 0%
- Hazardous Medication = 0%
- Latex = 0%
- Computer Monitor = 80%
- Domestic Animals = 0%
- Extreme Heat/Cold = 0%
- Fire Risk = 0%
- Hazardous Noise = 0%
- Heating Devices = 0%
- Hypoxia = 0%
- Laser/High Intensity Lights = 0%
- Magnetic Fields = 0%
- Moving Mechanical Parts = 0%
- Needles/Sharp Objects = 0%
- Potential Electric Shock = 0%
- Potential for Physical Assault = 0%
- Radiation = 0%
- Sudden Decompression During Flights = 0%
- Unprotected Heights = 0%
- Wet or Slippery Surfaces = 0%
Shift
Primarily for office workers - not eligible for shift differential
Disclaimer:
This job description is not intended, nor should it be construed to be an exhaustive list of all responsibilities, skills, efforts or working conditions associated with the job. It is intended to indicate the general nature and level of work performed by employees within this classification. Wages shown on independent job boards reflect market averages, not specific to any employer. We encourage candidates to talk to their Memorial Healthcare System recruiter to discuss actual pay rates, during the hiring process.
Memorial Healthcare System is proud to be an equal opportunity employer committed to workplace diversity. Memorial Healthcare System recruits, hires and promotes qualified candidates for employment opportunities without regard to race, color, age, religion, gender, sexual orientation, national origin, veteran status, disability, genetic information, or any factor prohibited by law. We are proud to offer Veteran’s Preference to former military, reservists and military spouses (including widows and widowers). You must indicate your status on your application to take advantage of this program. Employment is subject to post offer, pre-placement assessment, including drug testing. If you need reasonable accommodation during the application process, please call 954-276-8340 (M-F, 8am-5pm) or email TalentAcquisitionCenter@mhs.net
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- Education
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Senior Level Clinical Research Nurse Jobs: Frequently Asked Questions
How do I get a senior level clinical research nurse job?
Employers hiring at this level look for nurses who have led trial execution from site initiation through closeout, not just supported it. Holding a CCRC or CCRP credential signals that depth. Experience managing regulatory submissions, training junior staff, and serving as the primary contact for sponsors or IRBs puts a candidate well ahead of the field at the senior stage.
Which companies hire senior level clinical research nurses?
Companies hiring senior level clinical research nurses right now include Jobot, Colgate-Palmolive, and Guthrie, based on current listings on Migrate Mate as of October 2026. Hiring at this level comes primarily from large academic medical centers, contract research organizations, and pharmaceutical or biotech companies running Phase II through Phase IV trials.
Are there remote senior level clinical research nurse jobs?
Yes, though most senior roles still involve some on-site or travel component tied to site monitoring and investigator oversight. About 44% of senior level clinical research nurse openings are remote or hybrid as of October 2026, with fully remote positions most common in study coordination, regulatory affairs support, and protocol review roles at larger sponsors and CROs.
What makes a clinical research nurse role senior level?
Senior level roles carry ownership over trial operations rather than task execution. That means leading site management across multiple protocols, authoring or reviewing regulatory documents, mentoring coordinators and junior nurses, and serving as the clinical point of accountability for sponsors, IRBs, and investigators. The scope is broader and the decisions carry more downstream consequence than in mid-level positions.
Which industries hire the most senior level clinical research nurses?
Senior level clinical research nurse roles concentrate in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Education, based on current listings on Migrate Mate as of October 2026. These sectors drive hiring at this level because they run the largest trial portfolios, require experienced clinical oversight to satisfy regulatory standards, and need nurses who can lead teams through complex multi-site studies.