Icahn School of Medicine at Mount Sinai E-3 Visa Sponsorship Jobs USA
Icahn School of Medicine at Mount Sinai sponsors E-3 visas for Australian professionals in clinical, research, and academic roles. As a leading academic medical center, it has an established international hiring process, making it a viable path for qualified Australians in healthcare and biomedical fields.
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Get Access To All JobsPosition Status Full Time
Position Term Limited Term 1yr initial appointment with opportunity for renewal.
Position Type Postdoctoral Fellow, Medicinal Chemistry, Structure-Based Drug Design and Organic Synthesis
Position Overview
Icahn School of Medicine at Mount Sinai, NYC is seeking to hire a medicinal chemistry postdoctoral fellow for novel small molecule drug discovery projects in interesting therapeutic areas of unmet medical need including diabetes, orphan disease, neuroscience, IBD and oncology. Ph.D. in medicinal chemistry or organic synthesis required.
The role will require synthesis of novel medicinal compounds for testing in in vitro and in vivo assays that support the basic biology and drug discovery research efforts.
PhD in organic synthesis required with knowledge of heterocyclic chemistry, organometallic chemistry and the use of structure-based drug design using the Schrodinger suite desired.
Essential Skills
Strong background in organic chemistry in the area of organic synthesis, heterocyclic and organometallic chemistry; purification, characterization using NMR spectroscopy and analysis of reaction products using TLC and LC-MS techniques; methodology development; design of novel analogs; design and testing of synthetic routes to desired, novel compounds. Competence in Schrodinger suite of software for structure-based drug design and ligand docking is desired. 90% in lab medicinal chemistry; 10% structure-based drug design.
Duties and Responsibilities
- Preparation, purification and characterization of compounds in chemistry laboratory
- Documentation of all experiments in electronic lab notebooks (ELN) including written, publication quality, experimental procedures
- Operation and maintenance of laboratory instruments - HPLC and LC-MS, for example
- Safe laboratory habits and experimental practices
- Strong collaboration skills with chemistry team members and biology collaborator labs
Preferred Knowledge, Skills and Capabilities
Earned doctorate in organic chemistry with specific experience in total synthesis, heterocyclic and organometallic chemistry; demonstrated experience in the synthesis, purification, and analysis of complex organic molecules; experience with new method development, rapid analog and library synthesis techniques; multi-step synthetic processes and larger, multi-gram reaction scale-up. Microwave assisted synthesis. Excellent reaction trouble shooting skills. Experience with the safe handling of reactive and air-sensitive materials. Characterization of new molecules by NMR and LC-MS.
Competence with Schrodinger suite of software for structure-based drug design and ligand docking is desired with training available for those with an interest to learn this capability.
Excellent English written and oral communication skills. Ability to prepare and document experimental procedures for manuscript submission, patent applications with journal quality submission.
Opportunities for professional development
The position will allow the candidate to develop valuable new skills and experience in early drug discovery and chemical biology in a highly collaborative research environment.
These include:
- Collaborate to validate novel biological targets
- Chemical biology tool synthesis and development
- Structure-based drug design; Schrodinger software suite
- High throughput screening hit validation and analysis
- Hit and Lead identification and validation
- Lead optimization medicinal chemistry and pre-clinical candidate selection
- Analysis of in vitro and in vivo activity of compounds (pharmacodynamics)
- Chemo- and bio-informatics database development and data analysis
- Optimize physical-chemical properties and safety profile of drug molecules
- Study Absorption, Distribution, Metabolism and Excretion (ADME) properties
- Evaluate drug metabolism and pharmacokinetics (DMPK) in preclinical species
- External collaboration and public presentation skills
NIH Salary commensurate with experience and grant status
Job Type: Full-time
Pay: $74,999.00 - $75,000.00 per year
Benefits:
- Health insurance
- Paid time off
- Vision insurance
Work Location: In person
Position Status Full Time
Position Term Limited Term 1yr initial appointment with opportunity for renewal.
Position Type Postdoctoral Fellow, Medicinal Chemistry, Structure-Based Drug Design and Organic Synthesis
Position Overview
Icahn School of Medicine at Mount Sinai, NYC is seeking to hire a medicinal chemistry postdoctoral fellow for novel small molecule drug discovery projects in interesting therapeutic areas of unmet medical need including diabetes, orphan disease, neuroscience, IBD and oncology. Ph.D. in medicinal chemistry or organic synthesis required.
The role will require synthesis of novel medicinal compounds for testing in in vitro and in vivo assays that support the basic biology and drug discovery research efforts.
PhD in organic synthesis required with knowledge of heterocyclic chemistry, organometallic chemistry and the use of structure-based drug design using the Schrodinger suite desired.
Essential Skills
Strong background in organic chemistry in the area of organic synthesis, heterocyclic and organometallic chemistry; purification, characterization using NMR spectroscopy and analysis of reaction products using TLC and LC-MS techniques; methodology development; design of novel analogs; design and testing of synthetic routes to desired, novel compounds. Competence in Schrodinger suite of software for structure-based drug design and ligand docking is desired. 90% in lab medicinal chemistry; 10% structure-based drug design.
Duties and Responsibilities
- Preparation, purification and characterization of compounds in chemistry laboratory
- Documentation of all experiments in electronic lab notebooks (ELN) including written, publication quality, experimental procedures
- Operation and maintenance of laboratory instruments - HPLC and LC-MS, for example
- Safe laboratory habits and experimental practices
- Strong collaboration skills with chemistry team members and biology collaborator labs
Preferred Knowledge, Skills and Capabilities
Earned doctorate in organic chemistry with specific experience in total synthesis, heterocyclic and organometallic chemistry; demonstrated experience in the synthesis, purification, and analysis of complex organic molecules; experience with new method development, rapid analog and library synthesis techniques; multi-step synthetic processes and larger, multi-gram reaction scale-up. Microwave assisted synthesis. Excellent reaction trouble shooting skills. Experience with the safe handling of reactive and air-sensitive materials. Characterization of new molecules by NMR and LC-MS.
Competence with Schrodinger suite of software for structure-based drug design and ligand docking is desired with training available for those with an interest to learn this capability.
Excellent English written and oral communication skills. Ability to prepare and document experimental procedures for manuscript submission, patent applications with journal quality submission.
Opportunities for professional development
The position will allow the candidate to develop valuable new skills and experience in early drug discovery and chemical biology in a highly collaborative research environment.
These include:
- Collaborate to validate novel biological targets
- Chemical biology tool synthesis and development
- Structure-based drug design; Schrodinger software suite
- High throughput screening hit validation and analysis
- Hit and Lead identification and validation
- Lead optimization medicinal chemistry and pre-clinical candidate selection
- Analysis of in vitro and in vivo activity of compounds (pharmacodynamics)
- Chemo- and bio-informatics database development and data analysis
- Optimize physical-chemical properties and safety profile of drug molecules
- Study Absorption, Distribution, Metabolism and Excretion (ADME) properties
- Evaluate drug metabolism and pharmacokinetics (DMPK) in preclinical species
- External collaboration and public presentation skills
NIH Salary commensurate with experience and grant status
Job Type: Full-time
Pay: $74,999.00 - $75,000.00 per year
Benefits:
- Health insurance
- Paid time off
- Vision insurance
Work Location: In person
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Get Access To All JobsTips for Finding Icahn School of Medicine at Mount Sinai E-3 Visa Sponsorship Jobs USA
Align your degree to specialty occupation criteria
Mount Sinai's E-3 roles in clinical research, medicine, and biomedical science require a bachelor's degree or higher in a directly related field. Confirm your Australian qualification maps to the U.S. specialty occupation definition before applying, since a misaligned degree is the most common early disqualifier.
Target departments with international hiring patterns
Focus your outreach on Mount Sinai's research institutes, clinical departments, and graduate medical education programs, where international candidates are more routinely hired. Faculty-adjacent and postdoctoral research roles within these units tend to have existing E-3 filing infrastructure and less internal resistance to sponsorship.
Confirm E-3 eligibility before the offer stage
Raise your E-3 status early in the hiring conversation, not after an offer is extended. Mount Sinai's HR and legal teams are familiar with H-1B and EB-2 pathways, so clarifying that E-3 requires no lottery and no employer-side PERM filing often accelerates internal approval for sponsorship.
Check prevailing wage requirements before negotiating
Mount Sinai must certify through the DOL that your offered salary meets the prevailing wage for your role and location. Use the OFLC Wage Search to look up the wage level for your specific occupation code before salary negotiations so you're not caught off guard by the minimum threshold.
Use Migrate Mate to find verified E-3 filings
Search Migrate Mate to review Mount Sinai's DOL Labor Condition Application filing history by role and department. This lets you identify which job titles have active E-3 LCA records, so you can target your application toward positions where sponsorship is already established rather than starting from scratch.
Prepare your DS-160 and consular documents before your start date
E-3 visas are issued at the U.S. consulate in Australia, not through a change of status filed by the employer. Once Mount Sinai certifies your LCA, you'll complete your DS-160, book your consulate appointment, and attend your interview independently, so build that timeline into your expected start date conversation.
Icahn School of Medicine at Mount Sinai E-3 Visa Sponsorship: Frequently Asked Questions
Does Icahn School of Medicine at Mount Sinai sponsor E-3 visas?
Yes, Icahn School of Medicine at Mount Sinai sponsors E-3 visas for eligible Australian nationals. The institution supports international hiring across clinical, research, and academic roles and has established processes for work visa sponsorship. E-3 candidates should confirm their specific role qualifies as a specialty occupation before initiating the sponsorship conversation with HR.
Which roles at Mount Sinai typically receive E-3 sponsorship?
E-3 sponsorship at Mount Sinai is most common in roles that meet the specialty occupation requirement, including clinical research coordinators, postdoctoral researchers, physicians, and biomedical scientists. Academic and faculty-track positions within the school's research institutes and clinical departments are the most frequently sponsored, as these roles have clear degree-to-job-title alignment required for E-3 approval.
How do I start the E-3 application process at Mount Sinai?
After receiving a job offer, Mount Sinai's legal or HR team files a Labor Condition Application with the DOL on your behalf. Once the LCA is certified, you take it to your U.S. consulate appointment in Australia along with your DS-160, offer letter, and credential documents. USCIS is not involved in the E-3 consular process, which keeps the timeline tighter than H-1B visa.
How long does E-3 sponsorship take at Mount Sinai?
The DOL typically certifies the LCA within seven business days. After that, your consulate appointment wait time depends on the location and season, ranging from a few weeks to several weeks at Sydney, Melbourne, or Perth. Plan for four to eight weeks between offer acceptance and your visa stamp being ready, and discuss this timeline with your hiring manager early.
How do I find E-3 job openings at Mount Sinai?
Migrate Mate lists open roles at employers with verified E-3 LCA filing history, including Mount Sinai, so you can filter directly for positions where sponsorship is established. You can also search Mount Sinai's careers portal directly and filter for research, clinical, and academic postings. When applying, indicate your E-3 eligibility in your cover letter to flag that no lottery is required.
What is the prevailing wage for E-3 sponsorship at Icahn School of Medicine at Mount Sinai?
E-3 employers must pay at least the prevailing wage, determined when they file a Labor Condition Application with the Department of Labor. The rate is based on the role, location, and experience level, ensuring Australian hires are paid comparably to U.S. workers in the same position. You can look up prevailing wage rates for any occupation and location using the DOL's OFLC Wage Search tool.