Director Of Strategic Initiatives Jobs
Director Of Strategic Initiatives jobs are open across healthcare, technology, financial services, nonprofit, and higher education sectors, from senior manager to C-suite-adjacent levels, with specializations in organizational transformation, growth strategy, and cross-functional program leadership. Find a role that fits from the openings below and apply directly.
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INTRODUCTION
The Medical University of South Carolina (MUSC) Hollings Cancer Center seeks a highly organized and collaborative professional to serve as the System Director of Strategic Initiatives within the Cancer Integrated Center of Clinical Excellence (ICCE). This pivotal role supports the successful execution of MUSC’s System Cancer Strategic Plan, with a focus on statewide initiative coordination, regional cancer center development, access expansion, and preparation for NCI Comprehensive Cancer Center designation in 2028.
Reporting to the System Administrative Officer of the Cancer ICCE, and working in close partnership with the Executive Director of Cancer System Integration, the System Director of Strategic Initiatives will serve as a central point of coordination for project planning, milestone tracking, and alignment of efforts across Hollings leadership, site-based teams, academic departments, and ICCE partners.
The System Director, Strategic Initiatives will also serve as a key liaison to the MUSC Health Strategy Office, working collaboratively with the System Executive Director of Strategy to align cancer initiatives with the broader enterprise portfolio. The role includes other strategic projects that support operational readiness for upcoming milestones—including the launch of new regional cancer centers and the opening of MUSC’s new one-stop-shop cancer hospital in April 2030.
Position Summary
The Cancer ICCE System Director of Strategic Initiatives plays a key role in the delivery of MUSC’s cancer vision—driving disciplined execution of strategic priorities through collaborative planning, workstream oversight, and enterprise alignment.
Acting as a central point of coordination across campuses and functions, the System Director will lead tracking and operational follow-through for the System Cancer Strategic Plan, serve as the primary liaison to the MUSC Health Strategy Office, and oversee strategic program implementation across the cancer service line.
This role is ideal for a detail-oriented, systems-minded leader who brings clarity and structure to complex initiatives, and who thrives on supporting forward momentum across a wide network of contributors and stakeholders.
KEY RESPONSIBILITIES
Strategic Project Management (35%)
- Lead the development, execution, and performance tracking of strategic initiatives across the cancer service line.
- Support implementation of enterprise priorities such as new cancer center launches, the cancer hospital build-out, service expansion, and access optimization efforts.
- Coordinate multidisciplinary workgroups, facilitate decision-making, and monitor deliverables against timelines and goals.
- Escalate risks, barriers, or interdependencies that may impact progress, and propose mitigation strategies.
- Collaborate with Executive Director of Cancer Service Line Integration, site and ICCE leaders to support readiness planning for service launches, space transitions, and regional program rollouts.
- Provide structure and documentation for pilots, phased rollouts, and post-implementation assessments.
- Serve as a convener and translator between project owners, clinical leads, and operational teams to maintain alignment and accountability.
Strategic Planning & Initiative Execution (30%)
- Support the development of the cancer service line’s annual strategic work plan in collaboration with leadership.
- Track and report on progress toward strategic milestones, KPIs, and deliverables, ensuring transparency across stakeholders.
- Partner with Finance, Analytics, and Operations teams to align data, resource, and budget planning with initiative goals.
- Manage executive dashboards, written updates, and visual materials for internal reporting and Board-level presentations.
- Manage the planning and tracking of initiatives within the System Cancer Strategic Plan, ensuring timelines, deliverables, and accountability structures are in place.
- Coordinate projects across campuses, tumor programs, and administrative units to maintain alignment and visibility.
- Support operational readiness and implementation for major efforts such as new cancer center launches, ambulatory service expansion, and site activation plans.
Stakeholder Communication and Governance Support (20%)
- Support internal communications and engagement across departments, campuses, and stakeholder groups.
- Prepare briefing materials, slide decks, and executive summaries for steering committees and senior leadership forums.
- Assist with governance coordination, agenda setting, and documentation for cancer-related systemwide planning efforts.
Enterprise Strategy Liaison (15%)
- Serve as a key connector between the Cancer ICCE and the MUSC Health Strategy Office, ensuring cancer initiatives are represented in enterprise-level strategic planning and reporting cycles.
- Collaborate with the System Executive Director of Strategy to synchronize cancer goals and performance updates with systemwide initiatives.
BASIC QUALIFICATIONS
- Master’s degree in Healthcare Administration, Business, Public Health, or a related field required.
- Minimum 8–10 years of progressive experience in healthcare strategy, project management, service line execution, or enterprise planning.
- Proven ability to manage multiple initiatives in complex, matrixed healthcare or academic settings.
- Exceptional organizational skills and an ability to bring structure and discipline to dynamic environments.
- Demonstrated success in developing work plans, tracking performance, and translating strategic vision into operational execution.
- Adept at coordinating across teams and ensuring progress without needing to be the outward-facing representative.
- Experience working in oncology, academic medicine, or integrated health systems is strongly preferred.
PREFERRED QUALIFICATIONS
- Experience supporting strategy or planning functions within a cancer center or academic health system.
- Knowledge of Epic, Tableau, or project management software is a plus.
IDEAL ATTRIBUTES
- Strategic Translator: Able to move easily between long-term vision and short-term action.
- Organizational Engine: Brings structure, discipline, and energy to complex initiatives.
- Collaborative Partner: Works well across boundaries and maintains trust with multiple stakeholder groups.
- Mission-Aligned: Energized by improving cancer care access, experience, and integration across MUSC’s statewide system.
- Execution-Focused: Thrives on helping work move forward in a clear, structured, and accountable way.
- Detail-Oriented: Attuned to timelines, deliverables, and the practical steps required to move strategy from idea to implementation.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
LOCATION
Charleston, South Carolina
WORKER TYPE
Employee
WORKER SUB-TYPE
Regular
COST CENTER
CC004408 SYS - ICCE - Cancer
PAY RATE TYPE
Salary
PAY GRADE
Health-35
SCHEDULED WEEKLY HOURS
40
WORK SHIFT
Full Time
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
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Find JobsDirector Of Strategic Initiatives Job Market
A snapshot from current openings nationwide, updated as new roles post.
Who's Hiring
- City of New York1

- Emory Healthcare1

- Medical University of South Carolina1

- State of Vermont1

- The Catholic University of America1

Top Industries Hiring
- Education4
- Government & Public Sector2
- Healthcare & Medical Services2
- Law & Legal Services1
What Employers Look For
The qualifications that appear most often in director of strategic initiatives jobs.
- 7 or more years of experience in strategy, operations, or program management roles
- Proven ability to lead cross-functional initiatives from design through execution
- Experience presenting to executive leadership and board-level stakeholders
- Proficiency with project management tools such as Asana, Smartsheet, or similar platforms
- MBA or equivalent advanced degree in business, public policy, or a related field
- Familiarity with change management frameworks and organizational design principles
Tips for Your Director Of Strategic Initiatives Job Search
Reframe your resume around outcomes
Director of strategic initiatives roles attract candidates who can show measurable change, not just responsibilities held. Quantify initiative scope, timeline compression, or revenue impact on every bullet. Hiring panels at this level dismiss resumes that list duties without results.
Target openings tied to transformation cycles
Organizations post these roles most often during mergers, leadership transitions, or major growth phases. Filter for postings from companies that recently announced a restructure or new strategic plan, because those roles have real mandates and faster hiring cycles.
Apply early to roles that fit
Migrate Mate lists director of strategic initiatives openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Tailor your materials to the reporting line
A director of strategic initiatives reporting to the CEO needs different framing than one reporting to a division VP. Study the org chart context in the posting and align your cover letter language to the priorities of whoever you'd report to directly.
Prepare a portfolio of initiative blueprints
Interviewers at this level will ask you to walk through how you've built something from zero. Come with two or three documented examples, including your scoping process, stakeholder map, and how you handled a pivot mid-execution.
Negotiate scope before you negotiate compensation
These roles often carry ambiguous authority over budget and headcount. Before accepting an offer, clarify your decision-making mandate in writing. Scope creep without authority is the most common reason directors of strategic initiatives leave within the first year.
Director Of Strategic Initiatives Jobs: Frequently Asked Questions
Which companies are hiring the most director of strategic initiativess?
The companies hiring the most director of strategic initiativess right now include City of New York, Emory Healthcare, and Medical University of South Carolina, with the largest share of openings in Georgia, Maryland, and South Carolina, based on current listings on Migrate Mate as of June 2026. Healthcare systems, technology companies, and large nonprofit organizations consistently account for a significant portion of these postings.
How many director of strategic initiatives jobs are remote?
About 13% of director of strategic initiatives openings are fully remote or hybrid as of June 2026, reflecting the cross-functional and travel-heavy nature of the role. Sub-areas focused on digital transformation or technology strategy tend to offer the most remote flexibility, while roles tied to operational or facilities-intensive sectors more often require on-site presence.
How do you become a director of strategic initiatives?
Start by building a foundation in strategy consulting, business operations, or program management, where you develop skills in scoping complex problems and driving cross-functional work. Move into roles with increasing initiative ownership, seek exposure to executive decision-making processes, and build a documented portfolio of initiatives you led from concept through measurable outcome. An advanced degree, while not always required, strengthens candidacy.
Can I get hired as a director of strategic initiatives with limited experience?
Getting hired at the director level without deep experience is difficult, but candidates who have led high-visibility projects in adjacent roles, such as chief of staff, strategy analyst, or senior program manager, can make a credible case. Emphasizing initiative ownership, stakeholder influence, and executive exposure matters more than years of tenure in a formal director title.
What does the director of strategic initiatives interview process look like?
The process typically begins with a recruiter screen, followed by a structured interview with the hiring executive covering strategic thinking and past initiative examples. Later rounds often include a case study or presentation in which you are asked to outline an approach to a real organizational challenge. Final conversations frequently involve cross-functional stakeholders whose buy-in you would need on the job.
Where can I find and apply to director of strategic initiatives jobs?
You can find and apply to director of strategic initiatives jobs on Migrate Mate, which lists current openings from employers across the United States. Search the listings to find roles that match your background and apply directly to each one that fits.
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