Enterprise Sales Engineer Jobs in San Francisco, CA
Enterprise Sales Engineer jobs in San Francisco concentrate in SoMa, the Financial District, and Mission Bay, where cloud infrastructure, cybersecurity, and enterprise software companies run dense technical sales teams. Demand is strong across the Bay Area's established tech corridor, with Handshake, Anthropic, and Discord among those actively hiring. Find a role that fits below and apply directly.
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San Francisco, California | Primarily On-site
We are seeking a highly technical Enterprise Agent Systems Engineer to build and deploy advanced agent systems for large enterprise environments.
The Opportunity
This role combines strong software engineering with applied AI research judgment. You will work directly with technically sophisticated customers while building the agent systems, data pipelines, post-training workflows, and evaluation infrastructure required for production deployments.
Key Responsibilities
- Build and ship production agent systems for complex enterprise workflows.
- Develop data pipelines, orchestration systems, and evaluation harnesses.
- Run and analyze post-training workflows for customer-specific models and agents.
- Work directly with customer researchers and engineers.
- Evaluate whether performance issues originate in the model, environment, or evaluation framework.
- Translate customer workflows into robust, testable AI systems.
- Own technical deployments from implementation through production use.
Required Qualifications
- Strong software engineering fundamentals and demonstrated ability to ship production systems.
- Hands-on experience building agent systems, AI applications, or technical forward-deployed solutions.
- Ability to personally write and own production code.
- Strong understanding of evaluation, agent behavior, and production reliability.
- Ability to work across technologies and learn new stacks as required by the problem.
- Strong communication skills with technical enterprise stakeholders.
Seniority
The search is open from exceptional new graduates and early-career engineers through experienced senior engineers. Technical ability and demonstrated ownership are more important than years of experience.
Work Arrangement
The team is based in San Francisco and strongly prefers in-person collaboration. Limited flexibility may be considered for exceptional candidates, particularly experienced candidates elsewhere in the United States who can spend an initial period working on site.
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Find JobsEnterprise Sales Engineer Job Market in San Francisco
Who's Hiring
- Handshake16

- Anthropic10

- Discord6

- Scale AI6

- Lila Sciences6

Top Industries Hiring
- Technology & Software35
- Energy3
- Cybersecurity3
- Manufacturing3
- Science & Research3
Enterprise Sales Engineer Jobs in San Francisco: Frequently Asked Questions
How do I get a enterprise sales engineer job in San Francisco?
The most direct path is targeting San Francisco's SoMa and Mission Bay tech corridors, where cloud platforms, cybersecurity vendors, and data infrastructure companies run the largest enterprise sales engineering teams. Candidates who combine a technical background in software or networking with demonstrable customer-facing experience stand out locally. Familiarity with the Bay Area's enterprise buyer profile, including Fortune 500 procurement cycles and startup-scale deals, gives a clear edge over generalist applicants.
Which companies hire enterprise sales engineers in San Francisco?
Employers hiring enterprise sales engineers in San Francisco right now include Handshake, Anthropic, and Discord, based on current listings on Migrate Mate as of September 2026. San Francisco's market skews heavily toward established cloud and SaaS vendors as well as well-funded growth-stage companies, both of which rely on enterprise sales engineers to close complex, multi-stakeholder deals.
Are there remote enterprise sales engineer jobs in San Francisco?
Yes, though enterprise sales engineer roles are less remote-friendly than purely analytical positions because they often require on-site product demonstrations and in-person executive meetings. About 54% of enterprise sales engineer openings tied to San Francisco are remote or hybrid as of September 2026, with most structured as hybrid to accommodate customer travel. The technical pre-sales preparation work, such as building demos and writing solution documentation, is the portion most commonly done off-site.
How can I get a enterprise sales engineer job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is moving into a sales engineer role from a technical support, solutions consultant, or associate solutions engineer position at a mid-size SaaS company in SoMa or Mission Bay. Early-career candidates who build hands-on product knowledge and take on customer-facing duties in those adjacent roles get internal consideration first. San Francisco's density of growth-stage software companies also means associate or associate sales engineer titles appear regularly and serve as genuine on-ramps to full enterprise sales engineer responsibilities.
Which industries hire the most enterprise sales engineers in San Francisco?
The sectors hiring the most enterprise sales engineers in San Francisco are Technology & Software, Energy, and Cybersecurity, based on current listings on Migrate Mate as of September 2026. San Francisco's concentration of cloud infrastructure providers, cybersecurity vendors, and data platform companies means demand for enterprise sales engineers is driven by large recurring-revenue sales motions that depend heavily on technical pre-sales expertise.
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