Application Support Specialist Green Card Jobs
Application Support Specialist roles qualify for EB-2 and EB-3 green card sponsorship when the position requires a bachelor's degree in computer science, information systems, or a related field. Employers file PERM labor certification with the DOL before sponsoring permanent residency, making this one of the more accessible IT support paths to a green card.
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Get Access To All JobsCSV and Lab Application Support Specialist
Title: CSV and Lab Application Specialist
Location: Exton, PA
Reports to: Senior Director IT Infrastructure
Full-time (40 hrs./week) on site
Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Position/Job Summary:
As subject matter expert (SME), the CSV and lab application specialist define and maintain Frontage lab computer system validation program and responsible for testing, implementation, validation and day to day support of software applications.
The primary responsibilities of this position will be to perform lab software/application implementation and validation, administration, data management, user support, troubleshooting across Frontage lab to meet GxP requirements on computer systems in lab.
Roles & Responsibilities:
- Ensure Frontage lab global computer system validation program meets both business and regulatory requirements. Assist with client and FDA audits as necessary.
- Provide validation support for Bioanalytical, DMPK, Biologics, Clinical and IT as needed.
- Leverage validation efforts across sites and enterprise computer system solutions as appropriate.
- Provide support, training and guidance for validation projects.
- Maintain a computer inventory of computer system/software.
- Maintain validated state of software through periodic reviews, change controls and review of and implementation of upgrades as needed.
- Provide application support for lab software systems in general. Provide focused support for key systems: i.e., Watson LIMS/Sciex Analyst/QuickBase/IDBS E-WorkBook, eBinder etc.
- Resolve user problems and provide training as necessary.
- Evaluate and implement new software-based technologies as needed.
- Support user account and application access control.
- Manage and interact with system vendor to escalate and resolve issues.
- Provide support, instrument qualification and software validation, enhancement, and administration of laboratory instruments and related software.
- Support lab software application configurations related to lab instrumentations.
- Complete documentation for the support of software changes and upgrades.
- Drive technology improvements and efficiency opportunities to improve business and compliance.
- Contribute to change controls and procedures specific to laboratory software.
- Coordinate/interface/host vendors on site, when applicable.
- Provide training in software access and functionality.
- Ensure the software applications are validated to 21 CFR Part 1 compliance and always maintained in validated state.
- Other duties as assigned.
Education, Experience & Skills Required:
- Bachelor's degree in relevant scientific, engineering, or computer-based area with 5 years' experience in the pharmaceutical industry or equivalent combination of education and IT and/or lab experience.
- Knowledge of GxP regulatory requirements, computerized analytical systems (i.e., 21 CFR part 11) and data integrity.
- Expert in lab systems such as Watson LIMS, IDBS eNotebook, NUGENUSIS, Waters’ Empower Administration and other software programs, including Microsoft Office Applications.
- Must have GxP experience.
- Excellent organization, planning, and communication skills.
Salary and Benefits:
Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance.
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
CSV and Lab Application Support Specialist
Title: CSV and Lab Application Specialist
Location: Exton, PA
Reports to: Senior Director IT Infrastructure
Full-time (40 hrs./week) on site
Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Position/Job Summary:
As subject matter expert (SME), the CSV and lab application specialist define and maintain Frontage lab computer system validation program and responsible for testing, implementation, validation and day to day support of software applications.
The primary responsibilities of this position will be to perform lab software/application implementation and validation, administration, data management, user support, troubleshooting across Frontage lab to meet GxP requirements on computer systems in lab.
Roles & Responsibilities:
- Ensure Frontage lab global computer system validation program meets both business and regulatory requirements. Assist with client and FDA audits as necessary.
- Provide validation support for Bioanalytical, DMPK, Biologics, Clinical and IT as needed.
- Leverage validation efforts across sites and enterprise computer system solutions as appropriate.
- Provide support, training and guidance for validation projects.
- Maintain a computer inventory of computer system/software.
- Maintain validated state of software through periodic reviews, change controls and review of and implementation of upgrades as needed.
- Provide application support for lab software systems in general. Provide focused support for key systems: i.e., Watson LIMS/Sciex Analyst/QuickBase/IDBS E-WorkBook, eBinder etc.
- Resolve user problems and provide training as necessary.
- Evaluate and implement new software-based technologies as needed.
- Support user account and application access control.
- Manage and interact with system vendor to escalate and resolve issues.
- Provide support, instrument qualification and software validation, enhancement, and administration of laboratory instruments and related software.
- Support lab software application configurations related to lab instrumentations.
- Complete documentation for the support of software changes and upgrades.
- Drive technology improvements and efficiency opportunities to improve business and compliance.
- Contribute to change controls and procedures specific to laboratory software.
- Coordinate/interface/host vendors on site, when applicable.
- Provide training in software access and functionality.
- Ensure the software applications are validated to 21 CFR Part 1 compliance and always maintained in validated state.
- Other duties as assigned.
Education, Experience & Skills Required:
- Bachelor's degree in relevant scientific, engineering, or computer-based area with 5 years' experience in the pharmaceutical industry or equivalent combination of education and IT and/or lab experience.
- Knowledge of GxP regulatory requirements, computerized analytical systems (i.e., 21 CFR part 11) and data integrity.
- Expert in lab systems such as Watson LIMS, IDBS eNotebook, NUGENUSIS, Waters’ Empower Administration and other software programs, including Microsoft Office Applications.
- Must have GxP experience.
- Excellent organization, planning, and communication skills.
Salary and Benefits:
Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance.
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
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Get Access To All JobsTips for Finding Green Card Sponsorship as an Application Support Specialist
Align your degree to the role
PERM requires your degree field to match the job. A general IT or computer science degree supports most Application Support Specialist petitions, but a degree in an unrelated field can trigger PERM denials even when your work experience is strong.
Target employers with active PERM filings
Search the DOL's OFLC Wage Search to find companies that have filed PERM applications for Application Support or IT support roles. Employers with recent filings have an established sponsorship workflow, which shortens your path from offer to petition.
Use Migrate Mate to find sponsoring employers
Search Migrate Mate to filter Application Support Specialist jobs by green card sponsorship history. You'll see which employers have filed EB-2 or EB-3 petitions for this role, so you're not guessing about sponsorship willingness during the interview process.
Request the prevailing wage determination upfront
Before PERM is filed, your employer must obtain a prevailing wage determination from OFLC. Ask which wage level they intend to file at. Level I and II determinations are common for this role and affect both PERM compliance and your offered salary structure.
Prepare your employment history documentation now
USCIS scrutinizes I-140 petitions for Application Support roles when prior positions weren't formally titled. Gather reference letters, pay stubs, and official job descriptions from past employers before your petition stage to avoid delays from USCIS Requests for Evidence.
Application Support Specialist jobs are hiring across the US. Find yours.
Find Application Support Specialist JobsApplication Support Specialist Green Card Sponsorship: Frequently Asked Questions
Does an Application Support Specialist role qualify for EB-2 or EB-3 green card sponsorship?
Most Application Support Specialist positions qualify at the EB-3 skilled worker level, which requires a bachelor's degree or two years of training and experience. EB-2 sponsorship is available when the role genuinely requires an advanced degree or the employer can demonstrate a business necessity for higher qualifications. Your employer's HR or immigration counsel will determine which category applies based on the actual job requirements.
How does green card sponsorship differ from H-1B sponsorship for this role?
H-1B is a temporary nonimmigrant status requiring renewal every three years, subject to the annual lottery. An employer-sponsored green card through PERM leads to permanent residency with no renewal requirement and no cap concerns at the EB-3 level for most countries. The tradeoff is timeline: PERM labor certification alone can take six to twelve months before the I-140 petition even begins, whereas H-1B approval can happen within a few months for cap-exempt or premium-processed cases.
What does the PERM process look like for an Application Support Specialist?
Your employer files an Application for Permanent Employment Certification with the DOL, documenting that no minimally qualified U.S. worker was available for the role. This involves a recruitment phase with specific advertising requirements. Once DOL certifies the PERM, your employer files the I-140 immigrant petition with USCIS. You can then apply for adjustment of status or an immigrant visa once your priority date becomes current on the Visa Bulletin.
Where can I find Application Support Specialist jobs with green card sponsorship?
Migrate Mate filters job listings by verified green card sponsorship history, so you can identify employers who have actually filed PERM or EB-3 petitions for Application Support roles rather than relying on vague job postings. Targeting employers with a documented sponsorship track record reduces the risk of pursuing roles where sponsorship is aspirational rather than committed.
Can my employer start the green card process while I'm on H-1B status?
Yes. Employers routinely initiate PERM labor certification for workers already on H-1B status. Filing I-140 while on H-1B also activates AC21 portability protections after 180 days, meaning you can change employers in a similar role without losing your priority date. H-1B extensions beyond the standard six-year limit are also available once the I-140 is approved and your priority date isn't yet current.
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