Green Card Rare Disease Business Manager Jobs
Rare Disease Business Manager roles qualify for EB-2 and EB-3 green card sponsorship through PERM labor certification, which permanently transfers your status rather than requiring annual lottery cycles. Biotech and specialty pharma employers file I-140 petitions after PERM approval, sponsoring you for lawful permanent residency tied to this specialized commercial role.
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Get Access To All JobsJob title: Manager Franchise Operations Global Rare Diseases
Location: Cambridge, MA
About the Job
The Global Rare Diseases Franchise is a key strategic business unit within Sanofi, focused on developing and delivering life-changing therapies for patients with rare diseases worldwide. The Franchise Strategy and Operations team plays a critical role in enabling the success of this mission through operational excellence, strategic coordination, and effective cross-functional collaboration.
As a Manager within this team, you will be at the heart of supporting the team's operational effectiveness, helping to drive initiatives that impact patients with rare conditions globally. This role offers a unique opportunity to contribute to meaningful work in a dynamic environment, collaborating with talented professionals dedicated to transforming the lives of patients with rare diseases. You will gain broad exposure to various aspects of the rare disease business while developing expertise in operational management within a global pharmaceutical organization.
The ideal candidate will thrive in a fast-paced environment, demonstrate exceptional organizational abilities, and possess strong communication skills to effectively coordinate across multiple stakeholders and functions. This position offers growth potential and the chance to make a significant impact on the operational excellence of the Global Rare Diseases Franchise.
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.
About Sanofi
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main Responsibilities
Project Management:
- Support the Franchise Operations team with various ad hoc, time-bound priority projects for the franchise
Meeting Coordination:
- Coordinate and support town halls and employee engagement activities.
- Participant in and capture key insights and follow up from critical franchise operations-driven meetings.
Franchise Operations and Internal Communications:
- Manage the Franchise calendar
- Maintain and update team distribution lists to ensure proper communication flow
- Manage the global rare diseases mailbox, ensuring timely responses and appropriate routing of inquiries
- Support the team with Product Review Board submissions
- Partner with Corporate Communications to maintain communication channels across the franchise
- Oversee coordination with Graphic Design hub at the Franchise level
- Manage a variety of Franchise-wide routine processes associated with data collection & sharing.
Onboarding & Team Development:
- Deploy and maintain onboarding resources to ensure effective delivery to new team members based on project standards.
- Develop and facilitate several employee engagement opportunities for the Global Rare Franchise.
Communications & Stakeholder Management:
- Support internal communications strategy and execution
- Facilitate cross-functional collaboration on various projects and initiatives
- Manage the Franchise SharePoint & Teams site
About You
Basic Qualifications
- Bachelor's degree
- 3-5 years of experience in operations, project coordination, or administrative management
- Strong organizational and time management skills
- Proven ability to communicate effectively in teams, small groups and in a large group presentation environment
- Proficiency with Microsoft Office suite (Outlook, Excel, PowerPoint, Teams)
- Ability to work independently under minimal supervision and direction
- Travel approximately 10%
Preferred Qualifications
- Experience in pharmaceutical or healthcare industry
- Experience supporting senior leadership teams
- Project management certification or experience
Competencies
- Strong attention to detail and accuracy
- Excellent interpersonal skills and ability to work with diverse stakeholders
- Proactive problem-solving approach
- Ability to maintain confidentiality with sensitive information
- Adaptability and flexibility in a changing environment
- Collaborative team player with ability to work independently
Why Choose Us?
- Bring the miracles of science to life alongside a supportive, future-focused team
- Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Job title: Manager Franchise Operations Global Rare Diseases
Location: Cambridge, MA
About the Job
The Global Rare Diseases Franchise is a key strategic business unit within Sanofi, focused on developing and delivering life-changing therapies for patients with rare diseases worldwide. The Franchise Strategy and Operations team plays a critical role in enabling the success of this mission through operational excellence, strategic coordination, and effective cross-functional collaboration.
As a Manager within this team, you will be at the heart of supporting the team's operational effectiveness, helping to drive initiatives that impact patients with rare conditions globally. This role offers a unique opportunity to contribute to meaningful work in a dynamic environment, collaborating with talented professionals dedicated to transforming the lives of patients with rare diseases. You will gain broad exposure to various aspects of the rare disease business while developing expertise in operational management within a global pharmaceutical organization.
The ideal candidate will thrive in a fast-paced environment, demonstrate exceptional organizational abilities, and possess strong communication skills to effectively coordinate across multiple stakeholders and functions. This position offers growth potential and the chance to make a significant impact on the operational excellence of the Global Rare Diseases Franchise.
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.
About Sanofi
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main Responsibilities
Project Management:
- Support the Franchise Operations team with various ad hoc, time-bound priority projects for the franchise
Meeting Coordination:
- Coordinate and support town halls and employee engagement activities.
- Participant in and capture key insights and follow up from critical franchise operations-driven meetings.
Franchise Operations and Internal Communications:
- Manage the Franchise calendar
- Maintain and update team distribution lists to ensure proper communication flow
- Manage the global rare diseases mailbox, ensuring timely responses and appropriate routing of inquiries
- Support the team with Product Review Board submissions
- Partner with Corporate Communications to maintain communication channels across the franchise
- Oversee coordination with Graphic Design hub at the Franchise level
- Manage a variety of Franchise-wide routine processes associated with data collection & sharing.
Onboarding & Team Development:
- Deploy and maintain onboarding resources to ensure effective delivery to new team members based on project standards.
- Develop and facilitate several employee engagement opportunities for the Global Rare Franchise.
Communications & Stakeholder Management:
- Support internal communications strategy and execution
- Facilitate cross-functional collaboration on various projects and initiatives
- Manage the Franchise SharePoint & Teams site
About You
Basic Qualifications
- Bachelor's degree
- 3-5 years of experience in operations, project coordination, or administrative management
- Strong organizational and time management skills
- Proven ability to communicate effectively in teams, small groups and in a large group presentation environment
- Proficiency with Microsoft Office suite (Outlook, Excel, PowerPoint, Teams)
- Ability to work independently under minimal supervision and direction
- Travel approximately 10%
Preferred Qualifications
- Experience in pharmaceutical or healthcare industry
- Experience supporting senior leadership teams
- Project management certification or experience
Competencies
- Strong attention to detail and accuracy
- Excellent interpersonal skills and ability to work with diverse stakeholders
- Proactive problem-solving approach
- Ability to maintain confidentiality with sensitive information
- Adaptability and flexibility in a changing environment
- Collaborative team player with ability to work independently
Why Choose Us?
- Bring the miracles of science to life alongside a supportive, future-focused team
- Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
GD-SG
LI-GZ
LI-Onsite
vhd
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
See all Green Card Rare Disease Business Manager Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Green Card Rare Disease Business Manager Jobs.
Get Access To All JobsTips for Finding Green Card Sponsorship as a Rare Disease Business Manager
Document your rare disease commercial credentials
PERM requires your employer to prove no qualified U.S. worker is available. Gather performance records, launch metrics, and any cross-functional KOL or patient-advocacy work that distinguishes your rare disease commercial experience from general biotech sales backgrounds.
Target biotech employers with active PERM filings
Use Migrate Mate to filter companies that have filed PERM applications for business manager or commercial roles in rare disease or specialty pharma, so you're applying to employers already familiar with the sponsorship process rather than educating them from scratch.
Confirm your degree maps to EB-2 eligibility
EB-2 covers advanced-degree professionals, typically a master's or bachelor's plus five years of progressive experience. A life sciences, business, or pharmacy degree paired with documented rare disease commercial experience usually satisfies the advanced-degree professional standard USCIS applies.
Negotiate sponsorship timing before accepting an offer
PERM labor certification alone can take 12 to 18 months before USCIS even receives the I-140. Ask prospective employers whether they'll initiate PERM within your first year and whether they cover attorney fees, not just filing costs.
Understand how your birth country affects your green card wait
EB-3 backlogs for applicants born in India or China can stretch decades, while EB-2 may move faster. If your credentials support EB-2, request that designation explicitly during offer negotiation rather than defaulting to EB-3.
Verify prevailing wage before your PERM is filed
DOL's OFLC Wage Search publishes prevailing wage levels by occupation and geography. Confirm your offered salary meets or exceeds the Level II or Level III wage for your SOC code before PERM is submitted, or DOL will reject the application outright.
Green Card Rare Disease Business Manager: Frequently Asked Questions
Does a Rare Disease Business Manager role qualify for EB-2 or EB-3 green card sponsorship?
Most Rare Disease Business Manager positions qualify for both EB-2 and EB-3, depending on how the employer defines the minimum requirements in the job description. EB-2 applies if the role genuinely requires an advanced degree or equivalent. EB-3 covers professional roles requiring at least a bachelor's degree. Your employer's attorney typically recommends the category based on the actual job requirements and your qualifications.
How does the PERM green card process differ from H-1B sponsorship for this role?
H-1B visa is a temporary nonimmigrant visa subject to an annual lottery with a six-year maximum stay. PERM-based green card sponsorship leads to permanent residency with no annual renewal and no lottery. The tradeoff is time: PERM labor certification plus I-140 adjudication typically takes 18 to 36 months before you can adjust status, whereas H-1B can be in place within months. For rare disease roles requiring long-term relationship-building with payers and patient communities, green card sponsorship is often the more stable long-term arrangement.
How do I find Rare Disease Business Manager jobs where employers will sponsor a green card?
Use Migrate Mate to search for Rare Disease Business Manager roles filtered by employers with documented PERM filing history. Many specialty pharma and rare disease biotech companies sponsor green cards but don't always advertise it in job postings. Targeting employers who have filed PERM for similar commercial roles before significantly improves your chances of a successful sponsorship conversation.
Can my employer start the PERM process while I'm on an H-1B in this role?
Yes, and doing so is standard practice. Your employer can file the PERM labor certification while you're actively working in the role on H-1B status. Filing early also matters because once your I-140 is approved and your priority date is established, you may become eligible for H-1B extensions beyond the six-year cap under AC21 portability rules, provided the I-140 has been approved for at least 365 days.
What makes a Rare Disease Business Manager role harder to sponsor than a standard pharma sales position?
Rare disease commercial roles often involve smaller patient populations, specialized payer access strategies, and KOL engagement that employers may struggle to articulate as a defined specialty occupation in the PERM job description. If the job description is written too broadly, DOL may question whether U.S. workers could fill it. Working with an experienced immigration attorney to draft a job description that accurately reflects the specialized nature of rare disease commercialization reduces the risk of a PERM audit or denial.