Green Card Technical Director Jobs
Technical Director roles qualify for EB-2 or EB-3 green card sponsorship through PERM labor certification, which requires your employer to document that no qualified U.S. worker is available for the position. Employers in film, technology, and engineering regularly file PERM petitions for Technical Directors, making permanent residency a realistic path for credentialed foreign professionals in this field.
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Get Access To All JobsJob Title: Senior Director, Head of Technical Services, T1D Cell Therapy Manufacturing Operations
Department: Manufacturing Operations
Reports To: Vice President, Type 1 Diabetes Manufacturing Operations
Location: Boston, MA and Portsmouth, NH
Work Model: Full time on site or hybrid eligible
Vertex is seeking a Senior Director, Head of Technical Services to lead manufacturing-facing technical support for our Type 1 Diabetes Stem Cell Therapy Manufacturing Operations organization. This leader will oversee real-time GMP manufacturing support, troubleshooting, investigation support, operational process monitoring, manufacturing readiness, and implementation of approved process changes. The role requires deep experience in cell therapy manufacturing, strong people leadership, and the ability to partner effectively across Manufacturing, MSAT, Quality, Engineering, and Supply Chain.
Job Summary
At Vertex, we invest in scientific innovation to create transformative medicines for people with serious diseases. We are seeking an experienced and strategic leader to serve as Senior Director, Head of Technical Services for T1D Cell Therapy External Manufacturing Operations organization.
This role leads the manufacturing-facing technical function responsible for enabling reliable, compliant, and efficient execution of complex cell therapy manufacturing processes across clinical and commercial operations. The Head of Technical Services provides leadership for real-time manufacturing support, technical troubleshooting, investigation support, operational process monitoring, manufacturing readiness, and implementation of approved process changes in GMP operations.
This is a highly visible leadership role requiring expertise in cell therapy manufacturing, strong cross-functional influence, and a passion for translating process complexity into operational excellence.
Key Responsibilities
- Lead the Technical Services function supporting GMP manufacturing of cell-derived therapies for Type 1 Diabetes.
- Provide technical leadership for cell therapy manufacturing operations.
- Serve as the senior technical escalation point for manufacturing issues affecting batch execution, product quality, cycle time, or supply reliability.
- Lead technical troubleshooting and support timely resolution of deviations, investigations, atypical events, and process excursions.
- Drive operational process monitoring and trend review to identify emerging risks, improve execution consistency, and enhance manufacturing performance.
- Own Technical Services readiness for process changes, campaign startup, new product introduction, and transferred processes entering GMP manufacturing.
- Partner closely with Manufacturing, Quality Assurance, Quality Control, Engineering, Supply Chain, Regulatory, and CMC teams to support robust execution and inspection readiness.
- Build, develop, and mentor a high-performing team of technical subject matter experts supporting manufacturing operations.
- Foster a culture of quality, accountability, technical rigor, collaboration, inclusion, and patient focus.
Success in this role requires building a strong and effective partnership with Manufacturing, MSAT, and Quality while maintaining clear accountability across functions. This role is expected to be primarily onsite given the importance of close partnership with GMP manufacturing operations and cross-functional teams supporting manufacturing execution.
Minimum Qualifications
- Advanced degree in Bioengineering, Chemical Engineering, Bioprocess Engineering, Cell Biology, Molecular Biology, Pharmaceutical Sciences, or a related field.
- 15+ years of relevant industry experience in biotechnology, biopharmaceutical, cell therapy, or other advanced therapy manufacturing environments.
- 8+ years of progressive people leadership experience, including experience leading managers and cross-functional technical teams.
- Demonstrated success leading manufacturing-facing technical support in a GMP-regulated environment.
- Strong experience with deviations, investigations, troubleshooting, batch support, change implementation, and operational problem-solving.
- Proven ability to influence across Manufacturing, Quality, Engineering, Supply Chain, and process science organizations.
Leadership Profile
The ideal candidate will bring:
- strong technical depth in advanced therapy manufacturing
- a practical, solutions-oriented approach to troubleshooting and execution support
- strong judgment in high-stakes manufacturing environments
- the ability to create clarity at functional interfaces, especially between Technical Services, Manufacturing, and MSAT
- a track record of building teams and developing leaders
- a strong commitment to quality, compliance, and patient impact
About Vertex
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. Guided by our commitment to patients, we pursue advances in science, technology, and medicine to tackle diseases where we can make a meaningful difference.
Our teams bring together deep scientific expertise, operational excellence, and a bold sense of purpose. We are committed to fostering an environment where people can do their best work, grow their careers, and help deliver therapies that have the potential to transform lives.
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$216,900 - $325,300
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
- Hybrid: work remotely up to two days per week; or select
- On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
LI-Hybrid
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
Job Title: Senior Director, Head of Technical Services, T1D Cell Therapy Manufacturing Operations
Department: Manufacturing Operations
Reports To: Vice President, Type 1 Diabetes Manufacturing Operations
Location: Boston, MA and Portsmouth, NH
Work Model: Full time on site or hybrid eligible
Vertex is seeking a Senior Director, Head of Technical Services to lead manufacturing-facing technical support for our Type 1 Diabetes Stem Cell Therapy Manufacturing Operations organization. This leader will oversee real-time GMP manufacturing support, troubleshooting, investigation support, operational process monitoring, manufacturing readiness, and implementation of approved process changes. The role requires deep experience in cell therapy manufacturing, strong people leadership, and the ability to partner effectively across Manufacturing, MSAT, Quality, Engineering, and Supply Chain.
Job Summary
At Vertex, we invest in scientific innovation to create transformative medicines for people with serious diseases. We are seeking an experienced and strategic leader to serve as Senior Director, Head of Technical Services for T1D Cell Therapy External Manufacturing Operations organization.
This role leads the manufacturing-facing technical function responsible for enabling reliable, compliant, and efficient execution of complex cell therapy manufacturing processes across clinical and commercial operations. The Head of Technical Services provides leadership for real-time manufacturing support, technical troubleshooting, investigation support, operational process monitoring, manufacturing readiness, and implementation of approved process changes in GMP operations.
This is a highly visible leadership role requiring expertise in cell therapy manufacturing, strong cross-functional influence, and a passion for translating process complexity into operational excellence.
Key Responsibilities
- Lead the Technical Services function supporting GMP manufacturing of cell-derived therapies for Type 1 Diabetes.
- Provide technical leadership for cell therapy manufacturing operations.
- Serve as the senior technical escalation point for manufacturing issues affecting batch execution, product quality, cycle time, or supply reliability.
- Lead technical troubleshooting and support timely resolution of deviations, investigations, atypical events, and process excursions.
- Drive operational process monitoring and trend review to identify emerging risks, improve execution consistency, and enhance manufacturing performance.
- Own Technical Services readiness for process changes, campaign startup, new product introduction, and transferred processes entering GMP manufacturing.
- Partner closely with Manufacturing, Quality Assurance, Quality Control, Engineering, Supply Chain, Regulatory, and CMC teams to support robust execution and inspection readiness.
- Build, develop, and mentor a high-performing team of technical subject matter experts supporting manufacturing operations.
- Foster a culture of quality, accountability, technical rigor, collaboration, inclusion, and patient focus.
Success in this role requires building a strong and effective partnership with Manufacturing, MSAT, and Quality while maintaining clear accountability across functions. This role is expected to be primarily onsite given the importance of close partnership with GMP manufacturing operations and cross-functional teams supporting manufacturing execution.
Minimum Qualifications
- Advanced degree in Bioengineering, Chemical Engineering, Bioprocess Engineering, Cell Biology, Molecular Biology, Pharmaceutical Sciences, or a related field.
- 15+ years of relevant industry experience in biotechnology, biopharmaceutical, cell therapy, or other advanced therapy manufacturing environments.
- 8+ years of progressive people leadership experience, including experience leading managers and cross-functional technical teams.
- Demonstrated success leading manufacturing-facing technical support in a GMP-regulated environment.
- Strong experience with deviations, investigations, troubleshooting, batch support, change implementation, and operational problem-solving.
- Proven ability to influence across Manufacturing, Quality, Engineering, Supply Chain, and process science organizations.
Leadership Profile
The ideal candidate will bring:
- strong technical depth in advanced therapy manufacturing
- a practical, solutions-oriented approach to troubleshooting and execution support
- strong judgment in high-stakes manufacturing environments
- the ability to create clarity at functional interfaces, especially between Technical Services, Manufacturing, and MSAT
- a track record of building teams and developing leaders
- a strong commitment to quality, compliance, and patient impact
About Vertex
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. Guided by our commitment to patients, we pursue advances in science, technology, and medicine to tackle diseases where we can make a meaningful difference.
Our teams bring together deep scientific expertise, operational excellence, and a bold sense of purpose. We are committed to fostering an environment where people can do their best work, grow their careers, and help deliver therapies that have the potential to transform lives.
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$216,900 - $325,300
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
- Hybrid: work remotely up to two days per week; or select
- On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
LI-Hybrid
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
See all 922+ Green Card Technical Director Jobs
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Get Access To All JobsTips for Finding Green Card Sponsorship in Technical Director
Document your portfolio for PERM requirements
PERM requires your employer to define the minimum qualifications for your role before advertising it. Compile your technical credits, project scope records, and any specialized software certifications now so your employer's job description accurately reflects what you actually do.
Target employers with PERM filing history
Studios, broadcasters, and enterprise technology firms that have filed PERM petitions before are far less likely to stall on sponsorship paperwork. Search the DOL's OFLC disclosure data to identify which production companies and tech employers in your sector have sponsored Technical Directors previously.
Confirm the EB-2 versus EB-3 classification early
Technical Director roles often qualify under EB-2 if your employer's minimum requirement is a master's degree or a bachelor's plus five years of progressive experience. Clarify this with your employer before PERM filing, since the classification affects priority date wait times for certain nationalities.
Use Migrate Mate to find sponsoring employers
Search Migrate Mate to filter Technical Director openings by employers with active green card sponsorship history. This cuts the research time of manually cross-referencing OFLC data with job postings and surfaces roles where PERM sponsorship is already part of the hiring plan.
Understand the supervised recruitment window
PERM requires your employer to run DOL-mandated recruitment for at least 60 days and wait an additional 30 days before filing. If you're negotiating a start date, build at least four to five months into your timeline before USCIS receives the I-140 petition.
Align your O*NET occupational profile with the job description
PERM job descriptions must reflect the actual duties of the position. Cross-check your role's responsibilities against the O*NET profile for Technical Directors so your employer's PERM application doesn't contain duties inconsistent with DOL occupational definitions, which can trigger audit requests.
Green Card Technical Director: Frequently Asked Questions
Does a Technical Director role qualify for EB-2 or EB-3 green card sponsorship?
Technical Director positions can qualify under either category depending on how your employer defines the minimum requirements. EB-2 applies when the role requires a master's degree or equivalent, meaning a bachelor's degree plus at least five years of progressive, specialized experience. EB-3 covers roles requiring a bachelor's degree and at least two years of experience. Your employer sets the minimum in the PERM job description, so discussing this before filing is essential.
How does green card sponsorship differ from H-1B sponsorship for a Technical Director?
Green card sponsorship through PERM leads to permanent residency, not a temporary status subject to renewal. There is no annual cap lottery at the EB-3 level for most countries, so your employer can file at any time. The tradeoff is timeline: PERM, I-140, and adjustment of status typically takes two to four years for applicants from non-backlogged countries, compared to the H-1B visa's faster initial authorization but ongoing renewal dependency.
How do I find Technical Director jobs where employers are already open to green card sponsorship?
Migrate Mate lets you search Technical Director roles filtered by employers with documented green card sponsorship history, pulling from DOL OFLC disclosure data. This avoids the common problem of reaching the offer stage only to learn an employer has never navigated PERM before, which significantly delays or derails the sponsorship process.
What happens to my green card case if I change employers mid-process?
If your I-140 petition has been approved for at least 180 days, federal law allows you to port your priority date and underlying petition to a new employer in the same or a similar occupational classification. For Technical Directors, this typically means the new role must involve comparable technical leadership responsibilities. You'll need a new employer willing to file a new I-485 or continue your adjustment of status.
Can my employer start the PERM process before I have a visa to work in the United States?
Yes. PERM is an employer-driven DOL process that can begin while you're outside the country or on a different visa status. The I-140 can also be filed and approved before you enter the U.S. Once your priority date becomes current, you can apply for an immigrant visa through a U.S. consulate abroad rather than adjusting status from within the country.