H-1B Visa Senior Clinical Research Scientist Jobs
Senior Clinical Research Scientist roles qualify as H-1B visa specialty occupations under the life sciences SOC codes, requiring at least a bachelor's degree in a directly related field. Pharma, biotech, and CRO employers regularly file LCAs for these positions, making them a reliable category for H-1B sponsorship.
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Position Summary
The Buck Institute for Research on Aging is seeking a full-time Bioinformatics and Data Scientist or Postdoctoral Researcher to join a collaborative research team focused on aging, multi-omics, computational biology, and translational data science. This position offers a unique opportunity to work in an academic research environment with a close-knit, interdisciplinary team while collaborating with leading experts in aging biology, bioinformatics, clinical research, and computational science. The successful candidate will contribute to a five-year government-funded project focused on advancing computational and multi-omics approaches to better understand human aging, biological resilience, and healthspan. This role will support broader nationwide efforts to develop data-driven approaches that may ultimately improve how aging and age-related disease risk are measured, modeled, and addressed. The ideal candidate will have strong experience in bioinformatics, statistics, computational biology, human omics data analysis, and scientific communication. The position is well suited for an independent, highly motivated scientist who enjoys working across disciplines and contributing to both discovery-driven and translational research.
Key Responsibilities
2. Analyze, curate, and manage research data
- Perform bioinformatics and data science analyses. The successful candidate will analyze diverse biological and clinical datasets, including but not limited to:
- Proteomics
- Metabolomics
- Methylomics
- Survey data
- Integrative multi-omics datasets
- Human biological aging and omics-clock data
- Drug repurposing analyses
- Enrichment and pathway analyses
- Dimensionality reduction and clustering
- Classification methods, including random forests and support vector machines
- Neural network-based approaches
- Simple and multiple linear regression
- Parametric and non-parametric statistical analyses
Responsibilities will include:
- Curating, organizing, and preparing data for analysis and upload to central repositories
- Supporting data harmonization across projects, cohorts, and collaborators in accordance with data use agreements
- Reviewing and improving standard operating procedures for data transfer, quality control, and management
- Coordinating with internal and external teams to ensure timely collection, transfer, and analysis of data
- Attending project meetings and contributing to improvements in data workflows, systems, and documentation
- Ensuring data quality, reproducibility, and compliance with project requirements
3. Collaborate with scientific and administrative teams
The candidate will work closely with staff members, research scientists, computational biologists, principal investigators, and external collaborators. Responsibilities may include:
- Contributing to grant applications, progress reports, and scientific proposals
- Supporting manuscript preparation and journal article writing
- Creating publication-quality figures, tables, and data visualizations
- Presenting analyses and findings to interdisciplinary research teams
- Helping translate complex computational results into clear biological and scientific interpretations
Qualifications
Required Education and Experience
- Strong background in both human biology and bioinformatics
- PhD in Computational Biology, Bioinformatics, Data Science, Biostatistics, Systems Biology, Computer Science, or a related field
- Minimum of 2 years of professional experience in a biological, biomedical, or computational research environment
- Strong proficiency in R, Python, and Bash scripting
- Demonstrated experience analyzing biological or biomedical datasets
- Experience developing, implementing, and running bioinformatics workflows
Required Skills
- Strong analytical, mathematical, and creative problem-solving skills
- Excellent written and oral communication skills
- Ability to work both independently and collaboratively in a team-based research environment
- Strong organizational skills and attention to detail
- Ability to prioritize and execute multiple tasks across concurrent projects
- Experience with reproducible data analysis practices and documentation
- Ability to communicate technical results to both computational and non-computational audiences
- Interest in applying large language models, agentic AI, or related computational tools to biomedical research workflows
Preferred Qualifications
- Experience with FDA approval process
- Experience with building apps
Compensation And Benefits
- Salary range: $80,000–$85,000, commensurate with experience
- Full-time, onsite position
- Exciting, collaborative work environment at the forefront of aging research
- Opportunity to work with state-of-the-art technologies and interdisciplinary scientific teams
- Generous benefits package, including:
- Health insurance
- Paid parental leave
- Generous paid time off
- 401(k) with 5% employer match
- Work visa sponsorship available for qualified candidates
About The Buck Institute
Our success will ultimately change healthcare. At the Buck Institute for Research on Aging, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. The Buck is an independent, nonprofit institution located in Marin County, California, with the goal of increasing human healthspan, or the healthy years of life. Globally recognized as a pioneer and leader in efforts to target aging — the number one risk factor for diseases including Alzheimer’s disease, Parkinson’s disease, cancer, macular degeneration, heart disease, and diabetes — the Buck seeks to help people live better longer. We are an equal opportunity employer and strive to create an atmosphere where diversity of identity, experience, and background are welcomed, valued, and supported. Candidates who contribute to this diversity are strongly encouraged to apply.
To Apply
Interested candidates should click the Apply button to complete the online application. Please upload both:
- Your CV
- A brief statement of research interests, including the names and contact information for three references
See all 794+ H-1B Visa Senior Clinical Research Scientist Jobs
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Get Access To All JobsTips for Finding H-1B Visa Sponsorship as a Senior Clinical Research Scientist
Align your credentials to specialty occupation
Your degree field must directly relate to clinical research science, not just life sciences broadly. A biochemistry or pharmacology degree supporting a clinical trials role reads cleaner to USCIS than a general biology degree for the same position.
Verify prevailing wage before salary negotiations
Use the OFLC Wage Search to look up the Level II or III prevailing wage for your SOC code and target metro area. Your offered salary must meet or exceed this figure for the LCA to be certified by DOL.
Target employers with active LCA filing history
Search Migrate Mate to identify pharma and biotech companies that have filed LCAs for clinical research scientist roles. Employers with recent filing history are already familiar with the process and less likely to pull an offer over sponsorship complexity.
Clarify CRO versus sponsor employer structure early
Contract research organizations bill clients for your time, which can complicate the H-1B employer-employee relationship USCIS scrutinizes. Confirm whether the CRO or the pharma sponsor is the H-1B petitioner before accepting an offer.
Request premium processing for protocol-driven timelines
Clinical trial start dates are rarely flexible. If your role ties to a protocol launch or IND filing, ask your employer to file Form I-907 for premium processing so USCIS adjudicates within 15 business days instead of several months.
Document protocol authorship and regulatory submissions
Gather copies of protocols you authored, IND or NDA submissions you contributed to, and any IRB correspondence listing you as a named researcher. These materials strengthen the specialty occupation argument in your I-129 petition.
H-1B Visa Senior Clinical Research Scientist: Frequently Asked Questions
Does a Senior Clinical Research Scientist role qualify as an H-1B specialty occupation?
Yes. Senior Clinical Research Scientist positions require a bachelor's degree or higher in a directly related field such as pharmacology, biochemistry, or clinical sciences, which meets the USCIS specialty occupation standard. The role's requirement for specialized scientific judgment in protocol design and data interpretation reinforces that qualification. You can verify the occupational requirements through O*NET to support your petition.
Which types of employers sponsor H-1B visas for clinical research scientists?
Pharmaceutical companies, biotechnology firms, medical device manufacturers, and contract research organizations are the most active H-1B sponsors for this role. Academic medical centers with industry-funded trial units also file regularly. You can browse companies with verified LCA filing history for clinical research positions on Migrate Mate, which filters employers by role type and sponsorship activity.
How does the H-1B cap lottery affect clinical research scientist roles at CROs?
Most CROs are subject to the annual H-1B cap and lottery. If you aren't selected, some CROs can place you with a cap-exempt institution such as a nonprofit research hospital or university, which can file outside the lottery. Confirm whether your CRO has existing relationships with cap-exempt affiliates before registration opens each March.
Can I switch employers during an active clinical trial without losing H-1B status?
Yes, under H-1B portability rules you can start working for a new employer once they file a non-frivolous H-1B transfer petition, without waiting for USCIS approval. Your original status remains valid during adjudication. However, if your role is tied to a specific IND or protocol as the named investigator, the transition may create regulatory continuity issues beyond the immigration question.
What happens to my H-1B status if my clinical trial is terminated early?
If your employer ends your position before your H-1B period expires, you enter a 60-day grace period during which you can find a new sponsoring employer. A new employer must file an H-1B transfer petition before that window closes. If your trial termination is foreseeable, start identifying prospective employers through Migrate Mate early so you don't lose time during the grace period.