H-1B Visa Transformation Director Jobs
Transformation Director jobs with H-1B visa sponsorship sit at the intersection of enterprise strategy and organizational change, requiring a bachelor's degree or higher in business, management, or a related field. Employers filing H-1B petitions for this role must certify a prevailing wage through DOL and demonstrate the position qualifies as a specialty occupation.
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General Summary:
The Director, Commercial Transformation, is a key role within the Vertex Commercial Transformation Office, responsible for leading initiatives that will improve Vertex’s commercial capabilities, operating models and processes. Reporting to the Transformation Office Lead, this role will execute complex transformation programs, proactively perform forward looking views of commercial capability builds, as well as reactive assessments of gaps/opportunities that require immediate remediation. The Director of Transformation will assess, diagnose, and recommend how transformation initiatives are resourced, executed, and deployed across the organization.
Key Duties and Responsibilities:
- Serve as a trusted advisor to senior commercial and enterprise leaders on transformation opportunities and priorities.
- Ensure transformation initiatives have clear diagnosis, business case and defined benefit-realization plan.
- Lead transformation initiatives from start to finish, including securing budget, developing connectivity cross functionally and delivering the work.
- Cultivate strong partnerships with cross-functional teams to understand end user impact of transformation initiatives and organizational capacity for change.
- Prepare content for governance forums to drive effective and timely decision-making, and reading out to senior leadership on progress.
- Proactively respond to the dynamics of a changing external marketplace and scaling internal organization.
Executing for Results
- A leader that sets clear and challenging goals for transformation initiatives, tenacious and accountable in driving results.
- Exceptional project manager with proven ability to successfully navigate a fast-paced environment, adapt nimbly, and take smart risks.
- A partner with DTE to leverage technology, advance AI adoption and meaningfully influence our ways of working/ways of successfully commercializing Vertex medicines.
- A partner with Finance to establish investment assumptions and validate benefits.
Leading Adoption
- Clear and engaging communicator; makes the transformation story accessible and relevant for different audiences.
- End-user oriented – tuned into how change will land and impact the organizations to help leaders respond constructively.
- A leader who drives the organization's performance with an attitude of continuous improvement by being open to feedback and differing ideas.
- Monitor adoption and business impact after implementation; ensure corrective actions are taken when outcomes do not meet expectations.
Knowledge and Skills:
- Pharma/biotech industry experience preferred with commercialization experience either in global, regional, or market specific roles.
- Comfortable working in ambiguity, taking initiative, and navigating sensitive topics with multiple stakeholders.
- Strong analytical skills to seek out and assess data to get to the core of an issue/opportunity.
- Experience building business cases or conducting strategic analyses to inform senior decision-making.
- A passion for technology and creative problem-solving to direct the development or adoption of new, innovating solutions.
- Strong financial acumen or experience partnering with Finance to develop ROI analysis, cost-benefit analysis, and value realization.
- Superior cross-functional collaboration and influencing skills and ability to inspire and motivate teams.
Education and Experience:
- Bachelor's degree in a relevant field.
- Typically requires 10 years of relevant biotech/pharmaceutical commercial experience.
- Experience with branded drug products, management consulting, corporate strategy, change management, or organizational transformation.
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$213,600 - $320,400
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
- Hybrid: work remotely up to two days per week; or select
- On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
LI-Hybrid
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
Job Description
General Summary:
The Director, Commercial Transformation, is a key role within the Vertex Commercial Transformation Office, responsible for leading initiatives that will improve Vertex’s commercial capabilities, operating models and processes. Reporting to the Transformation Office Lead, this role will execute complex transformation programs, proactively perform forward looking views of commercial capability builds, as well as reactive assessments of gaps/opportunities that require immediate remediation. The Director of Transformation will assess, diagnose, and recommend how transformation initiatives are resourced, executed, and deployed across the organization.
Key Duties and Responsibilities:
- Serve as a trusted advisor to senior commercial and enterprise leaders on transformation opportunities and priorities.
- Ensure transformation initiatives have clear diagnosis, business case and defined benefit-realization plan.
- Lead transformation initiatives from start to finish, including securing budget, developing connectivity cross functionally and delivering the work.
- Cultivate strong partnerships with cross-functional teams to understand end user impact of transformation initiatives and organizational capacity for change.
- Prepare content for governance forums to drive effective and timely decision-making, and reading out to senior leadership on progress.
- Proactively respond to the dynamics of a changing external marketplace and scaling internal organization.
Executing for Results
- A leader that sets clear and challenging goals for transformation initiatives, tenacious and accountable in driving results.
- Exceptional project manager with proven ability to successfully navigate a fast-paced environment, adapt nimbly, and take smart risks.
- A partner with DTE to leverage technology, advance AI adoption and meaningfully influence our ways of working/ways of successfully commercializing Vertex medicines.
- A partner with Finance to establish investment assumptions and validate benefits.
Leading Adoption
- Clear and engaging communicator; makes the transformation story accessible and relevant for different audiences.
- End-user oriented – tuned into how change will land and impact the organizations to help leaders respond constructively.
- A leader who drives the organization's performance with an attitude of continuous improvement by being open to feedback and differing ideas.
- Monitor adoption and business impact after implementation; ensure corrective actions are taken when outcomes do not meet expectations.
Knowledge and Skills:
- Pharma/biotech industry experience preferred with commercialization experience either in global, regional, or market specific roles.
- Comfortable working in ambiguity, taking initiative, and navigating sensitive topics with multiple stakeholders.
- Strong analytical skills to seek out and assess data to get to the core of an issue/opportunity.
- Experience building business cases or conducting strategic analyses to inform senior decision-making.
- A passion for technology and creative problem-solving to direct the development or adoption of new, innovating solutions.
- Strong financial acumen or experience partnering with Finance to develop ROI analysis, cost-benefit analysis, and value realization.
- Superior cross-functional collaboration and influencing skills and ability to inspire and motivate teams.
Education and Experience:
- Bachelor's degree in a relevant field.
- Typically requires 10 years of relevant biotech/pharmaceutical commercial experience.
- Experience with branded drug products, management consulting, corporate strategy, change management, or organizational transformation.
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$213,600 - $320,400
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
- Hybrid: work remotely up to two days per week; or select
- On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
LI-Hybrid
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
See all 86+ H-1B Visa Transformation Director Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new H-1B Visa Transformation Director Jobs.
Get Access To All JobsTips for Finding H-1B Visa Sponsorship in Transformation Director
Frame your credentials around specialty occupation
Your degree field must align directly with the Transformation Director role. A business administration, organizational management, or industrial engineering degree paired with documented leadership scope strengthens the specialty occupation argument USCIS will evaluate in your I-129 petition.
Use the OFLC Wage Search before salary negotiations
Look up the prevailing wage for your target SOC code and metro area before any offer conversation. Your employer's LCA must certify at least that wage level, so knowing it in advance prevents an offer that DOL won't approve.
Find sponsors through Migrate Mate by role and location
Transformation Director roles are concentrated in a narrower set of employers than technical positions. Migrate Mate shows companies with verified H-1B LCA filing history for this occupation, so you target employers who have sponsored comparable strategic roles before.
Distinguish your role from general management titles
USCIS scrutinizes broad management titles for specialty occupation. Ask prospective employers to structure the job description around change management methodologies, digital transformation frameworks, and degree-specific analytical duties rather than general supervisory language.
Confirm each worksite before your LCA is certified
If your Transformation Director role spans multiple client or company locations, each worksite requires its own certified LCA before you can work there. Flag this with HR early so DOL filings cover every location in your project scope from day one.
Account for the full petition timeline in your start-date planning
H-1B status is initially granted for up to three years, with extensions possible up to a six-year maximum. Build at least three to six months of lead time into your offer negotiation to allow for LCA certification and I-129 processing before your intended start date.
H-1B Visa Transformation Director: Frequently Asked Questions
Does a Transformation Director role qualify as an H-1B specialty occupation?
Yes, when the position requires at least a bachelor's degree in business administration, organizational management, industrial engineering, or a closely related field, it typically qualifies. The employer must demonstrate in the I-129 petition that the role's duties are complex enough to require that specific degree, not just any bachelor's degree.
Which employers sponsor H-1B visas for Transformation Director roles?
Large consulting firms, enterprise technology companies, and global financial institutions account for most H-1B filings at this seniority level. Migrate Mate surfaces employers with verified LCA filing history for strategic and transformation leadership roles, so you can focus your search on organizations that have navigated this process before.
What SOC code applies to Transformation Director positions?
Most Transformation Director roles map to SOC 11-9199 (Managers, All Other) or SOC 13-1198 (Management Analysts), depending on whether the role emphasizes operational leadership or analytical consulting. The correct code affects your prevailing wage tier, so confirm with your employer's immigration counsel before the LCA is filed with DOL.
Can I transfer my H-1B to a new employer if I change Transformation Director roles?
Yes. Under H-1B portability rules, you can begin working for a new employer as soon as they file a new I-129 petition, without waiting for approval, as long as your previous H-1B was lawfully approved and you haven't fallen out of status. The new employer must file a fresh LCA reflecting the new worksite and wage level.
How does the H-1B prevailing wage requirement affect Transformation Director offers?
The employer must certify through DOL that your offered compensation meets or exceeds the prevailing wage for the role's SOC code in your work location. Transformation Director roles typically fall in the higher wage tiers. Use the OFLC Wage Search to verify the wage level before accepting an offer, since the LCA locks in that figure.