Histotechnologist Jobs
Histotechnologist jobs are open from entry-level to senior laboratory roles across hospitals, academic medical centers, pathology labs, and reference laboratories, with specializations in immunohistochemistry, frozen section processing, and special staining techniques. Scan the live roles below and apply to whichever ones fit.
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Under the direction of supervisor and/or program director develops, optimizes and performs histology, immunohistochemistry, immunofluorescence and fluorescent in-situ hybridization assays in support of research programs. Maintains equipment and records. Troubleshoots procedural and technical problems. Performs data entry of specimen information. Acts as a technical resource for research staff, students and trainees.
Perform routine and complex histology procedures on cells or tissue samples including harvesting, fixing, trimming, processing, embedding in paraffin, sectioning using a microtome or vibrating microtome, routine and special staining, and coverslipping. Sections frozen tissue specimen using a cryostat when necessary.
Prepare reagents, buffers, solutions and stains. Develop, optimize and perform immunohistochemistry, immunofluorescence and insitu hybridization assays.
Perform image capture, microscopy image analysis and processing of data using appropriate computer capture and analysis software.
Replace reagents, evaluate and performs daily maintenance of equipment and reagent systems. Order reagents, antibodies and tool parts to ensure adequate supplies for the work. Prepare dilutions and maintain all necessary reagents and antibodies according to standard operating procedure (SOP). Perform validation procedures on new antibodies or new protocols/SOP. Maintain a clean working area.
Follow the laboratory’s SOP for specimen handling and processing, test analyses, reporting and maintaining records of test examinations. Identifies problems that may adversely affect test performance or reporting of test results and troubleshoot to correct or notify immediately the supervisor or program director. Document all corrective actions taken when test systems deviate from laboratory’s established performance specifications. Maintain logbooks and slide files.
Adhere to the laboratory’s quality control policies, documents all quality control activities, instrument and procedural calibrations and maintenance performed. Maintain cleanliness of assigned instrumentation and/or equipment. Perform general maintenance and quality control of equipment. Complete and maintain preventative maintenance and troubleshooting records. Initiate requests for instrumentation/equipment repair and/or service through appropriate vendors. Take appropriate actions to keep interruptions in work flow to a minimum.
Demonstrate necessary computer skills, has knowledge of computer programs, and performs computer activities in order to effectively perform tests, data entry of specimen information, sample accessioning and sample tracking, collect statistics or review specimen information and equipment records.
Maintain a general working knowledge of laboratory safety, chemical and fire safety policies and procedures, and disaster plan.
Associate’s (A.A./A.S.) degree or higher in histotechnology from accredited College/University or approved hospital-based histotechnology program, or equivalent combination of education. Four (4) years of experience as a bench technologist in histology.
Required Credentials
N/A.
Preferred
Bachelor’s degree in a scientific discipline. Five (5) years of experience in standard and complex histological and histochemical techniques, and the development of novel immunohistochemistry and immunofluorescence detection methods. Histology Technician (HT), Histology Technologist (HTL), American Society for Clinical Pathology (ASCP) or equivalent certification.
Compensation Range
$32.87 - $49.31 per hourSalary Information
This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.
Disclaimer for Out of State Applicants
This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors.
Benefits Information
Seattle Children’s offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Additional details on our benefits can be found on our website www.seattlechildrens.org/careers/benefits.
About Us
Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE
Our founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families’ ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho – the largest region of any children’s hospital in the country.
U.S. News & World Report consistently ranks Seattle Children’s among the nation’s best children’s hospitals. For more than a decade, Seattle Children’s has been nationally recognized in key specialty areas. We are honored to be one of the nation’s very best places to care for children and the top-ranked pediatric hospital in Washington and the Pacific Northwest.
As a Magnet designated institution, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it’s delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.
Our Commitment
Seattle Children’s welcomes people of all experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our patients and families. Our organization recruits, employs, trains, compensates, and promotes based on merit without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.
The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves.
Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.
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Who's Hiring


What Employers Look For
The qualifications that appear most often in histotechnologist jobs.
- HT(ASCP) or HTL(ASCP) certification or eligibility required
- Proficiency in routine H&E staining and special histochemical stains
- Experience with immunohistochemistry (IHC) protocols and automation platforms
- Associate or bachelor's degree in histotechnology or a related biological science
- Familiarity with cryostat sectioning and intraoperative frozen section processing
- Knowledge of CAP accreditation standards and laboratory safety compliance
Tips for Your Histotechnologist Job Search
Lead with your HT or HTL credential
Certifications from the American Society for Clinical Pathology carry real weight in histotechnologist hiring. List your HT or HTL credential directly after your name in the resume header so screeners see it before anything else.
Quantify your tissue volume and turnaround
Hiring managers want to know how busy a lab you've worked in. Describe the daily case volume you processed and whether you consistently met CAP or Joint Commission turnaround standards, not just your list of techniques.
Target postings by accreditation type
Teaching hospitals, NCI-designated cancer centers, and large reference labs each have different throughput demands and staining menus. Filter openings by institution type to find environments that match your technical depth and preferred pace.
Apply early to roles that fit
Migrate Mate lists histotechnologist openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare for a bench skills conversation
Histotechnologist interviews frequently include scenario questions about troubleshooting staining artifacts, embedding orientation, or cryostat section quality. Walk through a specific problem you diagnosed, what you changed, and how the result improved.
Negotiate shift differential before accepting
Many histology labs run evening or weekend on-call coverage. If a posting lists a straight base figure, ask during the offer conversation whether shift differential or on-call pay applies to your schedule before you accept.
Histotechnologist Jobs: Frequently Asked Questions
Which companies are hiring the most histotechnologists?
Mayo Clinic, Baptist Health, and RC Dermatology are hiring the most histotechnologists right now, with openings concentrated in Wisconsin, New York, and Washington, based on current listings on Migrate Mate as of November 2026. Volume tends to track with large health systems and national reference laboratory networks.
How many histotechnologist jobs are remote?
About 0% of histotechnologist openings are fully remote or hybrid as of November 2026, reflecting the hands-on bench nature of most histology work. The sub-areas most likely to offer remote flexibility include quality assurance review, digital pathology image analysis, and laboratory consulting roles.
How do you become a histotechnologist?
You typically complete an accredited histotechnology program or earn a degree in a biological science with laboratory coursework, then gain bench experience in a clinical or pathology lab setting. After meeting eligibility requirements, you sit for the HT or HTL certification exam administered through the American Society for Clinical Pathology Board of Certification.
How do you get hired as a histotechnologist with little or no experience?
Completing your clinical rotations in a high-volume lab and documenting the specific techniques you performed gives you concrete talking points even without paid experience. Many hospitals hire new graduates into laboratory assistant roles that build toward a full histotechnologist position, and some reference labs offer structured training programs for recent program graduates who have passed or are eligible to sit for the HT exam.
What does the histotechnologist interview process look like?
Most interviews include a phone or video screen with HR, followed by a technical interview with the laboratory manager or lead histotechnologist covering staining protocols, troubleshooting scenarios, and equipment familiarity. Some institutions add a practical bench assessment where you demonstrate embedding, sectioning, or staining technique before a final conversation about schedule, lab culture, and fit.
Where can I find and apply to histotechnologist jobs?
You can find and apply to histotechnologist jobs on Migrate Mate, which lists current openings from across the United States in one place. Search the roles available, find the ones that match your credentials and preferred setting, and apply directly to each listing that fits.
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