Entry Level Lead Nurse Practitioner Jobs
New grad lead nurse practitioner jobs welcome recent graduates and entry level candidates with zero to two years of experience, where strong clinical rotation work or a preceptorship can carry more weight than a long resume. Most openings are on-site roles across Healthcare & Medical Services, Education, and Insurance, with employers like OSF HealthCare, Optum, and Novant Health hiring at this level now.
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INTRODUCTION
We are seeking a motivated, collaborative, and compassionate Advanced Practice Provider (APP) with a strong interest in oncology and patient care to join the department of Thoracic Radiation Oncology. The ideal candidate will be a Physician Assistant (PA) or Advanced Practice Registered Nurse (APRN) who is eager to learn, values teamwork, and possesses the ability to multitask in a dynamic outpatient oncology setting.
This role supports a multidisciplinary, patient focused environment where clinical excellence and compassionate care converge.
You will provide exceptional care and play a vital role in caring for adult patients with thoracic malignancies before, during, and after radiation treatment. This position provides a collaborative environment centered on exceptional patient care, fostering strong collaboration across disciplines and among supportive colleagues.
LOCATION
Location: Main Campus - Texas Medical Center (TMC)
SCHEDULE
Schedule: Monday - Friday, 8:00 AM - 5:00 PM
BASIC QUALIFICATIONS
- Strong ability to work in a fast-paced environment while demonstrating high emotional intelligence and adaptability.
- Excellent written and verbal communication skills.
- A team player with a commitment to patient-centered care.
- Preferred minimum of one year of experience as an APP in an inpatient setting or two years in an outpatient setting.
- Oncology experience and/or thoracic/pulmonary experience is preferred but not required.
KEY RESPONSIBILITIES
Patient Assessment & Care:
- Conduct comprehensive initial and ongoing physical examinations based on patient diagnosis.
- Identify normal/abnormal health characteristics and manage urgent patient care concerns.
- Perform clinical assessments for patients without scheduled appointments and make appropriate referrals.
- Assess and manage radiation-related side effects.
- Partner with supervising physicians to develop radiation clinical treatment plans, monitor outcomes, and initiate appropriate care interventions.
Implementation & Collaboration:
- Order diagnostic tests and therapeutic procedures in accordance with institutional and state requirements.
- Document and dictate consultation notes, follow-ups, and treatment summaries.
- Collaborate with the interdisciplinary healthcare team to optimize patient outcomes.
- Participate in cancer survivorship monitoring and management.
Education & Professional Development:
- Maintain up-to-date knowledge of Radiation Oncology practice, clinical research, and protocols.
- Serve as a clinical resource and educator for patients, families, and healthcare teams.
- Precept new APPs during their orientation, providing guidance on clinical operations and best practices.
Communication & Documentation:
- Utilize strong interpersonal, verbal, and non-verbal communication skills to effectively manage patient care situations.
- Ensure proper documentation of patient encounters, medication orders, and radiation prescriptions.
- Act as a liaison and advocate for patients, families, and interdisciplinary team members.
Education
Required:
Advanced Practice Registered Nurse
Master's Degree in Nursing or Doctor of Nursing Practice. May be waived for applicants who obtained recognition as an Advanced Practice Registered Nurse from the Texas State Board of Nursing prior to 1/1/2003.
Graduate education and related Texas Board of Nursing authorization must be consistent with clinical practice area and patient population.
Physician Assistant
Master's degree from an accredited Physician Assistant (PA) program by the Accreditation Review Commission on Education for the Physician Assistant (ARC-PA), except for Physician Assistants who graduated from a PA program prior to 2013.
Experience
Preferred: One year of experience in Advanced Practice Provider role.
LICENSURE / CERTIFICATION
Required:
Advanced Practice Registered Nurse
All of the following:
- Written authorization from the Texas Board of Nursing to function as an Advanced Practice Registered Nurse (APRN or ACNP or ACNPC or ACAGNP or AGACNP or ACNPC-AG or AGACNP or AGNP or ACPNP or ANP or AGNP or AGPCNP or FNP or GNP or PNP or PMHNP or WHNP or APNP). Related authorization must be consistent with clinical practice area and patient population.
- Basic Life Support (BLS). Pediatric Advanced Life Support (PALS) If working in the following departments: Pediatric - Patient Care (113100).
MAY BE REQUIRED: Authorization for limited prescriptive authority by the Texas Board of Nursing.
Physician Assistant
All of the following:
- PA certification by the National Commission of Certification of Physician Assistants.
- Licensed by the Texas State Board of Physician Assistant Examiners.
MAY BE REQUIRED: Eligible to be granted limited prescriptive authority by the State of Texas.
Must meet the American Heart Association Basic Life Support (BLS), ACLS (Advanced Cardiac Life Support) or PALS (Pediatric Advanced Life Support) if working in one of following department: Pediatrics - Patient Care (113100).
The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.
This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law.
ADDITIONAL INFORMATION
- Requisition ID: 184159
- Employment Status: Full-Time
- Employee Status: Regular
- Work Week: Days
- Minimum Salary: US Dollar (USD) 117,500
- Midpoint Salary: US Dollar (USD) 146,500
- Maximum Salary: US Dollar (USD) 176,500
- FLSA: exempt and not eligible for overtime pay
- Fund Type: Hard
- Work Location: Onsite
- Pivotal Position: No
- Referral Bonus Available?: Yes
- Relocation Assistance Available?: Yes
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Find JobsEntry Level Lead Nurse Practitioner Job Market
Who's Hiring
- OSF HealthCare43

- Optum21

- Novant Health19

- OneOncology16

- Dartmouth Health13

Top Industries Hiring
- Healthcare & Medical Services330
- Education72
- Insurance19
- Non-Profit & Social Services7
- Consulting & Professional Services2
Entry Level Lead Nurse Practitioner Jobs: Frequently Asked Questions
How do I get an entry level lead nurse practitioner job?
Start by targeting positions that explicitly welcome new graduates or candidates with limited experience, often labeled as 'new grad NP' or 'junior NP' roles. Highlight clinical rotations, preceptorships, and any specialty training in your application. A collaborative reference from a supervising physician or senior NP, combined with current board certification, gives entry level candidates a meaningful edge at this stage.
Which companies hire entry level lead nurse practitioners?
Companies hiring entry level lead nurse practitioners right now include OSF HealthCare, Optum, and Novant Health, based on current listings on Migrate Mate as of November 2026. At this level, hiring tends to come from health systems, outpatient clinics, and federally qualified health centers that have structured onboarding programs designed to support new practitioners.
Are there remote entry level lead nurse practitioner jobs?
Yes, though most entry level positions involve hands-on patient care and are on-site. About 3% of entry level lead nurse practitioner openings are remote or hybrid as of November 2026, with those roles typically concentrated in telehealth platforms, care management, or utilization review functions that do not require in-person clinical presence.
Are these new grad lead nurse practitioner jobs?
Yes, this page includes new grad, recent graduate, and junior lead nurse practitioner roles alongside other entry level postings. A new grad friendly posting typically welcomes zero to two years of experience, accepts clinical rotation hours or preceptorship in place of full-time NP experience, and does not require prior leadership tenure as a hard prerequisite.
Which industries hire the most entry level lead nurse practitioners?
Entry Level lead nurse practitioner roles concentrate in Healthcare & Medical Services, Education, and Insurance, based on current listings on Migrate Mate as of November 2026. These sectors tend to drive entry level hiring because they operate high patient volumes, maintain structured mentorship programs, and regularly need new practitioners to fill gaps created by expansion or provider turnover.