Manufacturing Jobs in San Francisco, CA
Manufacturing jobs in San Francisco are in active demand, concentrated in the Dogpatch, Bayview, and Potrero Hill industrial corridors, where biotech equipment, food production, and advanced electronics manufacturing anchor local hiring. Employers including OpenAI, Genentech, and Pacific Fusion are posting roles across production, quality control, and operations. Find a role that fits below and apply directly.
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Hardware - San Francisco
About the Team
OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño.
About the Role
We're seeking a Software Engineer to join our First-Party Hardware team. In this role, you will design, build, integrate, and validate the software used to manufacture, qualify, and deliver our hardware from the factory.
You will work across the stack to create the infrastructure that runs internally and externally to coordinate all aspects of the production process. You will create the critical tools and procedures to execute, capture, process, and present the data resulting from the end to end assembly and validation of our hardware across multiple vendors and sites.
This role is hands-on and high-ownership. You will work closely across teams both internal and external to define the standards that will be used across our products to ensure the velocity and quality of our 1P hardware. You will own the implementation, deployment, and output of these systems as well their continued maintenance and SLAs.
Location: San Francisco, CA (Hybrid: 3 days/week onsite). Relocation assistance available.
In this role, you will:
Design, develop, and maintain the software infrastructure for manufacturing process execution and data export.
Own integration across internal customers and vendor systems and processes.
Build and maintain the CI, release, and delivery pipeline of tooling to external partners.
Build and maintain internal systems to ingest, process, deliver, and visualize critical data for internal teams and systems.
Build system health monitoring, telemetry, remote diagnostics, and recovery paths that make manufacturing failures traceable and actionable.
Develop automation frameworks and monitoring for board bring-up, rack bring-up, qualification, manufacturing readiness, deployment readiness, and long-term reliability.
Package engineering releases into manufacturing-ready software recipes: images, versions, logs, limits, remediation mapping, provisioning hooks, secure artifact handling, and traceable data export.
Debug complex production issues spanning hardware, firmware, kernel, services, networking, power, thermals, boot, provisioning, manufacturing, test, and cloud services.
Partner with hardware, firmware, security, networking, infrastructure, manufacturing, operations, and external engineering teams to define software contracts, unblock bring-up, and drive issues to closure.
Produce durable architecture notes.
You might thrive in this role if you have:
7+ years of hands-on experience software, hardware diagnostics, and cloud infrastructure.
Strong programming skills in C, C++, Rust or similar systems languages, with experience building reliable software for real hardware.
Familiarity with scripting in languages such as shell and python as used in automation systems.
Familiarity with Linux-based hardware platforms, OpenBMC, Redfish, firmware update systems, kernel drivers, and fleet management software.
Demonstrated ability to debug live hardware using logs, packet captures, firmware traces, bus captures, lab hosts, BMC journals, Linux tooling, and carefully controlled experiments.
Experience with hardware bring-ups.
Ability to reason across software, firmware, hardware, manufacturing, and operations boundaries, and to turn ambiguous problems into clear requirements, designs, tests, and decisions.
Proven track record working with external vendors, manufacturing partners, or partner engineering teams to define deliverables, review technical work, and drive issues to closure.
Familiarity with platform security topics such as secure boot, firmware signing, device provisioning, attestation, certificate handling, trusted update flows, or access-control design is a plus.
To comply with U.S. export control laws and regulations, candidates for this role may need to meet certain legal status requirements as provided in those laws and regulations.
About OpenAI
OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core the full spectrum of humanity.
We are an equal opportunity employeration, or other applicable legally protected characteristic.
Background checks for applicants will be administered in accordance with applicable lawation technology systems and related data security obligations.
To notify OpenAI that you believe this job posting is non-compliant. No response will be provided to inquiries unrelated to job posting compliance.
We are committed to providing reasonable accommodations to applicants with disabilities.
At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.
Compensation
$310K – $460K + Offers Equity
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Who's Hiring
- OpenAI291

- Genentech48

- Pacific Fusion48

- TWIST BIOSCIENCE48

Manufacturing Jobs in San Francisco: Frequently Asked Questions
How do I get a manufacturing job in San Francisco?
Focus your search on San Francisco's industrial neighborhoods: Dogpatch, Bayview-Hunters Point, and Potrero Hill host the highest concentration of production facilities, from specialty food and beverage manufacturers to biotech equipment and clean-tech hardware firms. Candidates with hands-on machine operation, quality assurance, or supply chain experience stand out. Applying directly to mid-size manufacturers in these districts, rather than large staffing agencies, tends to move faster in this market.
Which companies hire manufacturings in San Francisco?
Companies currently hiring manufacturings in San Francisco include OpenAI, Genentech, and Pacific Fusion, per current listings on Migrate Mate as of September 2026. San Francisco's manufacturing employers tend to skew toward specialty production, life sciences equipment, and sustainable consumer goods, with a mix of established local producers and well-funded startups building hardware in the city.
Are there remote manufacturing jobs in San Francisco?
Yes, though only for specific functions: hands-on production, assembly, and quality inspection roles are almost always on-site by nature. About 100% of manufacturing openings tied to San Francisco are remote or hybrid as of September 2026, concentrated in roles like manufacturing engineering, supply chain coordination, and production planning where the core work is analytical rather than floor-based.
How can I get a manufacturing job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is through production associate or manufacturing technician roles at smaller specialty food, beverage, or hardware companies in Dogpatch and Bayview. These employers often prioritize reliability and mechanical aptitude over a lengthy resume. Completing a short certificate in lean manufacturing or machine operation through City College of San Francisco strengthens your application and signals readiness for floor work.
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