Manufacturing Jobs in North Carolina
Manufacturing jobs in North Carolina are in strong demand, concentrated in automotive components, pharmaceuticals, aerospace parts, and food processing, with openings at every level from production operators to plant managers. Charlotte, Greensboro, and Raleigh-Durham anchor the highest hiring volumes, where employers like Corning, Caterpillar, and Honeywell maintain long-running North Carolina operations. The most sought-after specialties right now are CNC machining, quality assurance, and industrial maintenance. See the openings below and apply to the ones that match your experience.
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Showing 5 of 136+ Manufacturing jobs
About This Role
Our factories run 24/7 operations. Our manufacturing teams work 12-hour shifts (either Days or Nights) on a 2-2-3 calendar rotation.
Shift Details: This role follows a 2-2-3 calendar rotation on nights (6:00 PM – 6:00 AM ET)
Internal Shift Details: Red Nights rotating schedule
Our Manufacturing Associates perform processing steps and manufacturing support activities in our Drug Substance facility in Research Triangle Park (RTP). These teams are the backbone of our operations – each playing a critical role in delivering our therapies to the patients who need them.
Our teams are organized by the steps in the biomanufacturing process that they operate in; including – Upstream (Cell Culture), Downstream (Purification), and Media & Solution Preparation. Manufacturing Associates perform these critical steps in a clean environment governed by Current Good Manufacturing Practices (cGMP).
This role’s primary focus is Downstream (Purification):
- Column Chromatography
- Viral Filtration
- Ultra-Filtration
- Bulk Dispensing of the drug substance
What You’ll Do
- Execute daily manufacturing activities, to include operating process equipment and executing validation protocols according to cGMP Standard Operating Procedures (SOPs)
- Document and record all cGMP data & information (including deviations) for processing steps and equipment activities
- Create and revise key documentation like batch records, SLRs, and equipment logbooks
- Assist in conducting in-process sampling and sampling analysis (pH, Conductivity, Protein Concentration, Osmolarity, etc.)
- Help maintain a clean and safe work environment, always focusing on audit readiness of process areas
- Be a team player and leader; always showing up to contribute your energy and focus
- Actively participate and lead in training and development initiatives, both for personal growth and for that of your team members
Who You Are
You’re driven by a mission to save lives and bring a deep sense of purpose to the work you do. Biomanufacturing is complex, and you thrive in fast-paced environments where learning agility, problem-solving, and adaptability are essential.
Required Skills for a Manufacturing Associate III: $25.96 - $34.13 Pay Range
- The following combination of academic and/or relevant experience may be considered:
- Bachelor’s degree from an accredited college or university, STEM preferred and at minimum .5 years of direct experience
- A BioWorks Certificate or associate's degree, STEM preferred and at minimum 1 year of direct experience
- A High School Diploma (or equivalent) and at minimum of 1.5 years of direct experience
- Previous experience in a cGMP environment.
- Demonstrated ability to follow Standard Operating Procedures (SOPs) and adhere to Good Documentation Practices (GDP).
- Experience or understanding of working in an aseptic or cleanroom environment.
- Understanding of process automation and software systems (e.g. DeltaV, LIMS, etc.).
- Previous pipetting experience in a laboratory or manufacturing environment preferred.
Required Skills for a Manufacturing Associate IV: $31.25 - $40.87 Pay Range
- The following combination of academic and/or relevant experience may be considered:
- Bachelor’s degree from an accredited college or university, STEM preferred and at minimum 2 years of direct experience
- A BioWorks Certificate or associate's degree, STEM preferred and at minimum 2.5 year of direct experience
- A High School Diploma (or equivalent) and at minimum of 3 years of direct experience
- Previous experience in a cGMP environment.
- Demonstrated ability to follow Standard Operating Procedures (SOPs) and adhere to Good Documentation Practices (GDP).
- Experience working in an aseptic or cleanroom environment.
- Understanding of process automation and software systems (e.g. DeltaV, LIMS, etc.). Previous pipetting experience in a laboratory or manufacturing environment preferred.
Job Level: Entry Level
Additional Information
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being ; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year Employee Resource Groups participation
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our Biogen.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
About This Role
Our factories run 24/7 operations. Our manufacturing teams work 12-hour shifts (either Days or Nights) on a 2-2-3 calendar rotation.
Shift Details: This role follows a 2-2-3 calendar rotation on nights (6:00 PM – 6:00 AM ET)
Internal Shift Details: Red Nights rotating schedule
Our Manufacturing Associates perform processing steps and manufacturing support activities in our Drug Substance facility in Research Triangle Park (RTP). These teams are the backbone of our operations – each playing a critical role in delivering our therapies to the patients who need them.
Our teams are organized by the steps in the biomanufacturing process that they operate in; including – Upstream (Cell Culture), Downstream (Purification), and Media & Solution Preparation. Manufacturing Associates perform these critical steps in a clean environment governed by Current Good Manufacturing Practices (cGMP).
This role’s primary focus is Downstream (Purification):
- Column Chromatography
- Viral Filtration
- Ultra-Filtration
- Bulk Dispensing of the drug substance
What You’ll Do
- Execute daily manufacturing activities, to include operating process equipment and executing validation protocols according to cGMP Standard Operating Procedures (SOPs)
- Document and record all cGMP data & information (including deviations) for processing steps and equipment activities
- Create and revise key documentation like batch records, SLRs, and equipment logbooks
- Assist in conducting in-process sampling and sampling analysis (pH, Conductivity, Protein Concentration, Osmolarity, etc.)
- Help maintain a clean and safe work environment, always focusing on audit readiness of process areas
- Be a team player and leader; always showing up to contribute your energy and focus
- Actively participate and lead in training and development initiatives, both for personal growth and for that of your team members
Who You Are
You’re driven by a mission to save lives and bring a deep sense of purpose to the work you do. Biomanufacturing is complex, and you thrive in fast-paced environments where learning agility, problem-solving, and adaptability are essential.
Required Skills for a Manufacturing Associate III: $25.96 - $34.13 Pay Range
- The following combination of academic and/or relevant experience may be considered:
- Bachelor’s degree from an accredited college or university, STEM preferred and at minimum .5 years of direct experience
- A BioWorks Certificate or associate's degree, STEM preferred and at minimum 1 year of direct experience
- A High School Diploma (or equivalent) and at minimum of 1.5 years of direct experience
- Previous experience in a cGMP environment.
- Demonstrated ability to follow Standard Operating Procedures (SOPs) and adhere to Good Documentation Practices (GDP).
- Experience or understanding of working in an aseptic or cleanroom environment.
- Understanding of process automation and software systems (e.g. DeltaV, LIMS, etc.).
- Previous pipetting experience in a laboratory or manufacturing environment preferred.
Required Skills for a Manufacturing Associate IV: $31.25 - $40.87 Pay Range
- The following combination of academic and/or relevant experience may be considered:
- Bachelor’s degree from an accredited college or university, STEM preferred and at minimum 2 years of direct experience
- A BioWorks Certificate or associate's degree, STEM preferred and at minimum 2.5 year of direct experience
- A High School Diploma (or equivalent) and at minimum of 3 years of direct experience
- Previous experience in a cGMP environment.
- Demonstrated ability to follow Standard Operating Procedures (SOPs) and adhere to Good Documentation Practices (GDP).
- Experience working in an aseptic or cleanroom environment.
- Understanding of process automation and software systems (e.g. DeltaV, LIMS, etc.). Previous pipetting experience in a laboratory or manufacturing environment preferred.
Job Level: Entry Level
Additional Information
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being ; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year Employee Resource Groups participation
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our Biogen.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
See All 136+ Manufacturing Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find Manufacturing JobsManufacturing Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Manufacturing Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Electronics & Hardware
- Manufacturing
- Technology & Software
- Retail
- Medical Devices
What North Carolina Employers Look For
The qualifications that appear most often in manufacturing jobs across North Carolina.
- High school diploma or GED required by most North Carolina manufacturing employers
- One or more years of experience operating production machinery or assembly line equipment
- Familiarity with quality control standards such as ISO 9001 or lean manufacturing principles
- Ability to read and interpret technical drawings, blueprints, or work instructions
- Physical capability to stand for extended periods and lift up to fifty pounds
- Forklift certification or eligibility to complete employer-sponsored forklift training
Manufacturing Jobs in North Carolina: Frequently Asked Questions
How do you become a manufacturing worker in North Carolina?
Most entry-level manufacturing roles in North Carolina require a high school diploma or GED and on-the-job training provided by the employer. Community colleges such as Guilford Technical Community College and Central Piedmont Community College offer certificates in industrial systems technology and machining that strengthen your application. For advanced roles like electrical or HVAC work inside facilities, a North Carolina trades license from the North Carolina State Board of Examiners may be required.
Which companies hire manufacturing workers in North Carolina?
Employers hiring manufacturings in North Carolina right now include Biogen, TE Connectivity, and FujiFilm, based on current listings on Migrate Mate as of September 2026. North Carolina's mix of pharmaceutical, automotive, and aerospace manufacturing means hiring is spread across both large multinational plants and regional production facilities throughout the Piedmont and I-85 corridor.
Which North Carolina cities have the most manufacturing jobs?
Charlotte, Holly Springs, and Winston-Salem have the most manufacturing job openings in North Carolina. Charlotte leads because of its large automotive suppliers and distribution infrastructure, while Greensboro and the Triad region are anchored by textile, aerospace, and logistics employers, and smaller metros like Concord and Asheboro draw volume from dedicated industrial parks along the Piedmont corridor.
Are there remote manufacturing jobs in North Carolina?
Yes, but they're rare. About 19% of manufacturing openings tied to North Carolina are remote or hybrid as of September 2026, reflecting how hands-on the work typically is. The portions most likely to allow remote or hybrid schedules are quality engineering, supply chain coordination, and production planning roles that do not require a physical presence on the plant floor.
How can I get hired as a manufacturing worker in North Carolina with little or no experience?
The most realistic entry path is applying directly to production associate or general labor postings at large North Carolina plants, which routinely hire candidates without prior experience and train on the job. Employers like Tyson Foods, Freightliner, and Caterpillar run structured new-hire onboarding programs at their North Carolina facilities. Completing a short certificate in manufacturing fundamentals at a North Carolina community college and obtaining a forklift operator card gives candidates a measurable edge over applicants with no credentials at all.
Where can I find and apply to manufacturing jobs in North Carolina?
You can find and apply to manufacturing jobs in North Carolina on Migrate Mate, which lists current openings from employers hiring across the state right now. Search the listings to find roles that match your skills and experience level, then apply directly to the ones that fit.
See All 136+ Manufacturing Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find Manufacturing Jobs