Nurse Practitioner Jobs in Durham, NC

Nurse Practitioner jobs in Durham, North Carolina are concentrated in Research Triangle Park, Duke University's Medical Center area, and the Northgate corridor, with strong demand across academic medical centers, community health networks, and specialty clinics. Employers hiring right now include Duke Health, WakeMed, and Avance Care. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles22
Top employerDuke Health
Work type100% On-site
Top credentialBLS Certification
Companies hiring12

Showing 5 of 22+ Nurse Practitioner jobs

Duke Health
Advanced Practice Provider - Duke Breast Risk Assessment Clinic
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Duke Health
New 1m ago
Advanced Practice Provider - Duke Breast Risk Assessment Clinic
Duke Health
Durham, North Carolina
Customer Service
Healthcare Administration
Human Resources
Overseeing health insurance pre-certification
10,000+

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Duke Health
Nurse Practitioner or Physician Assistant - Pediatric Cardiothoracic Surgery
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Duke Health
New 1m ago
Nurse Practitioner or Physician Assistant - Pediatric Cardiothoracic Surgery
Duke Health
Durham, North Carolina
Program Management
Project Management
Quality Assurance & Testing (QA Testing)
PALS Certification
10,000+

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EmergeOrtho
Advanced Practice Provider
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EmergeOrtho
New 1m ago
Advanced Practice Provider
EmergeOrtho
Durham, North Carolina
Allied Health
Healthcare Administration
Patient Services & Wellbeing
1,001-5,000

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WakeMed Health & Hospitals
NP or PA, MyCare 365 Primary Care & Urgent Care - Float position
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WakeMed Health & Hospitals
New 1m ago
NP or PA, MyCare 365 Primary Care & Urgent Care - Float position
WakeMed Health & Hospitals
Durham, North Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
Master's degree in nursing
10,000+

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Raleigh Neurology Associates, P.A.
Advanced Practice Provider (Neurology) - Outpatient NP or PA
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Raleigh Neurology Associates, P.A.
New 1m ago
Advanced Practice Provider (Neurology) - Outpatient NP or PA
Raleigh Neurology Associates, P.A.
Durham, North Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
201-500

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See All 22 Nurse Practitioner Jobs in Durham

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Nurse Practitioner Job Market in Durham

Who's Hiring

  • Duke Health
    Duke Health9
  • WakeMed
    WakeMed2
  • Avance Care
    Avance Care2
  • Optum
    Optum1
  • Concentra
    Concentra1

Top Industries Hiring

  • Healthcare & Medical Services7
  • Consulting & Professional Services1

Nurse Practitioner Jobs in Durham: Frequently Asked Questions

How do I get a nurse practitioner job in Durham?

Focus your search on Durham's two dominant hiring corridors: Duke Health's medical campus and the federally qualified health centers and community clinics serving the Walltown, Bragtown, and Southpoint corridors. Academic medical systems, private specialty practices, and urgent care groups all hire actively here. Candidates with experience in primary care, cardiology, or oncology have a clear edge in Durham's market, and bilingual skills in Spanish are a practical differentiator at community health sites.

Which companies hire nurse practitioners in Durham?

Employers hiring nurse practitioners in Durham right now include Duke Health, WakeMed, and Avance Care, based on current listings on Migrate Mate as of July 2026. Durham's employer mix leans heavily toward large academic health systems, multi-specialty physician groups, and federally funded community health organizations serving the Research Triangle region.

Are there remote nurse practitioner jobs in Durham?

Yes, though remote opportunities are limited by nature for nurse practitioners, since most roles require hands-on patient care. About 0% of nurse practitioner openings tied to Durham are remote or hybrid as of July 2026, concentrated in telehealth triage and chronic disease management programs. Durham's health systems have expanded telehealth panels, particularly for behavioral health and post-discharge follow-up care.

How can I get a nurse practitioner job in Durham with little or no experience?

The most realistic entry path in Durham is a new-graduate residency or fellowship at one of the area's academic health systems, which structure supervised clinical rotations for newly licensed NPs. Durham's federally qualified health centers and community clinics also hire new graduates more readily than private specialty practices. Completing clinical hours in Durham itself during your program builds direct relationships with hiring managers, which consistently outweighs a polished resume at the entry level.

Which industries hire the most nurse practitioners in Durham?

The sectors hiring the most nurse practitioners in Durham are Healthcare & Medical Services and Consulting & Professional Services, based on current listings on Migrate Mate as of July 2026. Durham's identity as a research university city and biotech hub drives concentrated demand in academic medicine and clinical research settings, alongside robust community health infrastructure serving a rapidly growing population.

See All 22 Nurse Practitioner Jobs in Durham

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