Nurse Practitioner Jobs in Durham, NC
Nurse Practitioner jobs in Durham, North Carolina are concentrated in Research Triangle Park, Duke University's Medical Center area, and the Northgate corridor, with strong demand across academic medical centers, community health networks, and specialty clinics. Employers hiring right now include Duke Health, WakeMed, and Avance Care. Scan the live roles below and apply to whichever ones fit.
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At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and the greater community. No matter where your talents lie, join us and discover how we can advance health together.
Duke Health Integrated Practice
Duke Health Integrated Practice comprises more than 110 primary and specialty outpatient clinics, extending the reach of the Duke Health mission across the state of North Carolina.
Job Location
Duke Breast Surgical Oncology Clinic, 20 Duke Medicine Circle, Durham, NC
Duke Regional Cancer Center, 3643 N Roxboro St, Durham, NC
Job Summary
We are seeking an Advanced Practice Provider in the Duke Breast Risk Assessment Clinic located in Durham, NC to work in collaboration with the clinic director to continue to expand the program and provide expert-level care to patients with risk factors for breast cancer. The APP will work with attending physicians to provide direct patient care services, collect and document data, conduct diagnostic/therapeutic procedures, and order/schedule imaging studies and professional consultations.
Primary hours will be Monday through Friday, day shift, with flexible hours to meet the needs of the patients.
Job Duties & Responsibilities
- Provide direct patient care services for new and return patients, both in person and virtually, including triage, physical exams, collecting and documenting data, and coordinating care.
- Counsel and educate patients on breast cancer risk and management recommendations.
- Conduct diagnostic and therapeutic procedures (such as skin punch biopsies).
- Order and schedule imaging, laboratory studies, and professional consultations.
- Conduct pre-authorizations for recommended studies, as ordered by the APP and/or other team members.
- Prescribe appropriate interventions and medications.
- Follow-up test results and coordinate ongoing care, including but not limited to imaging and pathology results.
- Conduct timely e-communication consults from referring providers.
- Communicate verbally and in writing all pertinent patient information to collaborating physicians, referring providers, nursing staff, patient resource manager, and other relevant healthcare providers.
- Provide timely documentation in the electronic medical record of all relevant data including results of tests; laboratory results; patients’ condition and response to therapies/interventions; communications with colleagues.
- Patient care responsibility will be completed in an out-patient clinic setting and will not involve in-patient or operating room time.
- Facilitate educational experiences for trainees (students, residents, fellows, etc) and orientation sessions for other team members.
- Seek out and participate in learning opportunities through reading, attending seminars/webinars/conferences, etc, to enhance knowledge in breast cancer risk.
- Serve as a role model and mentor for team members, demonstrating professionalism in conduct, speech, appearance, work habits, customer service, communication style, critical thinking skills, resource utilization, and problem resolution.
- In collaboration with the clinic director (with dedicated time):
- Serve as an ongoing resource and primary point of contact for patients and providers in the Breast Risk Assessment Clinic.
- Collaborate the DCI New Patient Coordinators, Breast Imaging, the Clinical Cancer Genetics Program, Breast Surgical Oncology, and Plastics and Reconstructive Surgery,
- Working with epic champions/informatics specialists, create and manage note and discussion templates for team distribution and use.
- Communicate with team regarding practice advisories, updates, expectations, policies, and procedures.
- Review clinic metrics regularly to help develop and coordinate quality improvement projects and best practice initiatives.
- Working with DCI and Surgery administration, help create and optimize clinic templates to facilitate patient care and utilize clinic space appropriately.
- Lead and facilitate team meetings to identify, prioritize, and discuss any issues relating to clinical/professional practice and the success of the interprofessional team.
Job Eligibility Requirements
Education
- Nurse Practitioners: Work requires completion of an accredited Nurse Practitioner program, with a master’s degree in nursing.
- Physician Assistants: Work requires completion of an accredited Physician Assistant program. A bachelor’s degree required; master's degree strongly preferred.
Certification
- BLS required.
- Additional training and/or certification favored, such as APP certification through ASBrS, completion of the City of Hope Intensive Course in Genomic Cancer Risk Assessment, and CGRA (Cancer Genetics and Risk Assessment) certification through NCoBC
License
- Nurse Practitioners: Must have current or compact RN licensure & NP approval to practice in the state of North Carolina. National certification as a NP required.
- Physician Assistants: Must be licensed in the state of NC and be certified as a Physician Assistant by the National Commission on Certification of Physician Assistants.
Experience
- 5+ years of APP experience highly desired.
- Experience in a high-risk breast clinic preferred.
- Experiences in a breast surgery clinic and/or hereditary cancer clinic favored.
Job Hours
Monday-Friday, day shift, with flexibility to meet clinic needs
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
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Find Nurse Practitioner JobsNurse Practitioner Job Market in Durham
Who's Hiring
- Duke Health9

- WakeMed2

- Avance Care2

- Optum1

- Concentra1
Top Industries Hiring
- Healthcare & Medical Services7
- Consulting & Professional Services1
Nurse Practitioner Jobs in Durham: Frequently Asked Questions
How do I get a nurse practitioner job in Durham?
Focus your search on Durham's two dominant hiring corridors: Duke Health's medical campus and the federally qualified health centers and community clinics serving the Walltown, Bragtown, and Southpoint corridors. Academic medical systems, private specialty practices, and urgent care groups all hire actively here. Candidates with experience in primary care, cardiology, or oncology have a clear edge in Durham's market, and bilingual skills in Spanish are a practical differentiator at community health sites.
Which companies hire nurse practitioners in Durham?
Employers hiring nurse practitioners in Durham right now include Duke Health, WakeMed, and Avance Care, based on current listings on Migrate Mate as of July 2026. Durham's employer mix leans heavily toward large academic health systems, multi-specialty physician groups, and federally funded community health organizations serving the Research Triangle region.
Are there remote nurse practitioner jobs in Durham?
Yes, though remote opportunities are limited by nature for nurse practitioners, since most roles require hands-on patient care. About 0% of nurse practitioner openings tied to Durham are remote or hybrid as of July 2026, concentrated in telehealth triage and chronic disease management programs. Durham's health systems have expanded telehealth panels, particularly for behavioral health and post-discharge follow-up care.
How can I get a nurse practitioner job in Durham with little or no experience?
The most realistic entry path in Durham is a new-graduate residency or fellowship at one of the area's academic health systems, which structure supervised clinical rotations for newly licensed NPs. Durham's federally qualified health centers and community clinics also hire new graduates more readily than private specialty practices. Completing clinical hours in Durham itself during your program builds direct relationships with hiring managers, which consistently outweighs a polished resume at the entry level.
Which industries hire the most nurse practitioners in Durham?
The sectors hiring the most nurse practitioners in Durham are Healthcare & Medical Services and Consulting & Professional Services, based on current listings on Migrate Mate as of July 2026. Durham's identity as a research university city and biotech hub drives concentrated demand in academic medicine and clinical research settings, alongside robust community health infrastructure serving a rapidly growing population.
Related Jobs in North Carolina
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