Nurse Practitioner Jobs in Greenville, SC
Nurse Practitioner jobs in Greenville, South Carolina are concentrated in the Medical District along Grove Road, in the expanding Verdae corridor, and across downtown Greenville's growing network of outpatient and specialty clinics, with strong demand in primary care, urgent care, and family medicine. Employers actively hiring include Prisma Health, Prisma Health Urgent Care, and CVS Health. Find a role that fits below and apply directly.
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As a national leader in value-based care, we offer senior living communities and skilled nursing facilities a wide range of solutions (including on-site primary care services, Accountable Care Organizations, and Medicare Advantage Special Needs Plans) proven to enhance health outcomes, streamline operations, and create new financial opportunities.
Founded in 2021, we've grown quickly—now serving 200,000+ seniors in 1,500+ communities across 32 states. Our team includes more than 1,000 clinicians alongside care coordinators, analysts, operators, and professionals from all backgrounds, all working together to deliver high-quality, proactive solutions for senior living operators and those they care for.
Ranked #147 on the Inc. 5000 list of America's fastest-growing private companies, we're just getting started. If you're looking to make a meaningful impact on the senior healthcare landscape, you're in the right place—and we look forward to working with you.
For more information about our company, visit CuranaHealth.com.
Summary
At Curana Health, we’re reimagining how seniors receive compassionate, comprehensive psychiatric care. We are seeking an experienced and mission-driven Psychiatric Nurse Practitioner (PMHNP) to join our growing team and provide high-quality mental health support across Skilled Nursing Facilities (SNF), Long-Term Care (LTC), Assisted Living (AL), and Independent Living (IL) communities.
This is more than a job—it’s an opportunity to make a lasting difference in the lives of adults and older adults while enjoying a supportive environment and true work-life balance.
As a Psychiatric Nurse Practitioner at Curana Health, you’ll help shape the future of geriatric behavioral health care. You’ll work alongside a collaborative, multidisciplinary care team to deliver personalized psychiatric services, ensuring continuity of care across the post-acute and long-term care continuum. Your expertise will empower residents, support families, and improve outcomes for an underserved population.
Essential Duties & Responsibilities
- Psychiatric Care and Rounding: Conduct patient rounds and manage psychiatric care within SNF, LTC, AL, and IL settings.
- Collaborative Care Coordination: Partner with attending physicians, consulting specialists, referral sources, and facility staff to ensure comprehensive, coordinated care.
- Patient Evaluation and Management: Assess and manage the mental health needs of residents, perform physical exams, and gather complete medical histories.
- Diagnostics and Therapeutics: Order and interpret lab and diagnostic tests, make preliminary diagnoses, and develop effective therapeutic care plans for mental and physical health.
- Medication and Treatment Management: Prescribe and administer medications and treatments; provide injections as necessary.
- Patient and Family Education: Educate patients and families on medications, care plans, and preventive mental health practices.
- Acute Care Collaboration: Work alongside physicians and facility teams to address acute psychiatric and medical needs promptly and effectively.
What We Offer
We know that caring for seniors takes more than just medical expertise—it takes support, tools, and opportunities to grow. That’s why Curana offers:
Unlimited earning potential with competitive compensation models.
Autonomy of practice backed by strong clinical and administrative support.
Cutting-edge care model that empowers you to transform senior healthcare.
Data-driven tools & AI solutions to better understand and manage patient needs.
Streamlined communication with smart texting and modern tech platforms.
Professional development, including CME support
Quality incentives with bonuses tied to patient outcomes and care excellence.
Work-life balance supported by generous paid time off.
Benefits
Medical, Dental, Vision insurance
401(k) with company match
Company-paid short- and long-term disability
Comprehensive malpractice coverage
UpToDate subscription for clinical decision support
Full-time employees are eligible for Curana Health’s full benefits package. Part-time employees may be eligible for limited benefits as applicable.
Qualifications
- Graduation from an accredited Nurse Practitioner program and ANCC certification as a Psychiatric Mental Health Nurse Practitioner (PMHNP).
- Active DEA license.
- BLS and ACLS certification.
- Current Nurse Practitioner license in the state of practice.
See All 39 Nurse Practitioner Jobs in Greenville
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Find Nurse Practitioner JobsNurse Practitioner Job Market in Greenville
Who's Hiring
- Prisma Health19

- Prisma Health Urgent Care2

- CVS Health1

- Crossroads1

- DOCS Health1

Top Industries Hiring
- Healthcare & Medical Services
- Consulting & Professional Services
Nurse Practitioner Jobs in Greenville: Frequently Asked Questions
How do I get a nurse practitioner job in Greenville?
Focus your search on Greenville's Medical District, where large health systems and specialty practices cluster along Grove Road and Patewood Drive, then expand to urgent care groups and federally qualified health centers serving underserved communities in and around the city. Candidates with primary care or family practice experience have the strongest footing here. Bilingual skills and experience with Medicaid or underinsured populations give applicants a real edge in Greenville's growing community health sector.
Which companies hire nurse practitioners in Greenville?
Companies currently hiring nurse practitioners in Greenville include Prisma Health, Prisma Health Urgent Care, and CVS Health, per current listings on MigrateАте as of July 2026. Greenville's employer mix ranges from large regional health systems and hospital-affiliated multispecialty groups to independent urgent care chains and community health organizations expanding their mid-level provider teams.
Are there remote nurse practitioner jobs in Greenville?
Yes, though remote opportunities are limited by the hands-on nature of most nurse practitioner roles. About 8% of nurse practitioner openings tied to Greenville are remote or hybrid as of July 2026, with the bulk of those positions concentrated in telehealth triage, chronic disease management, and behavioral health consulting rather than primary or acute care.
How can I get a nurse practitioner job in Greenville with little or no experience?
The most realistic entry path in Greenville is through large health system residency or transition-to-practice programs, which give new graduates supervised clinical hours and a structured ramp into independent practice. Community health centers serving the West Greenville and downtown corridors frequently hire new graduates willing to work in underserved settings. Urgent care groups across the Verdae and Woodruff Road corridors also hire new NPs for supervised roles, especially those with strong emergency or acute care RN backgrounds.
Which industries hire the most nurse practitioners in Greenville?
Most nurse practitioner openings in Greenville sit in Healthcare & Medical Services and Consulting & Professional Services, per current listings on Migrate Mate as of July 2026. Greenville's rapid population growth and the continued expansion of hospital-affiliated outpatient campuses in the Patewood and Verdae areas have made ambulatory and multispecialty care the dominant drivers of local NP hiring.
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