Nurse Practitioner Jobs in South Carolina
Nurse Practitioner jobs in South Carolina are consistently active, with demand concentrated in primary care, psychiatric and behavioral health, and family practice settings across hospital systems, federally qualified health centers, and rural clinics. The largest hiring activity centers on Columbia, Greenville, and Charleston, where major employers such as Prisma Health, MUSC Health, and Bon Secours anchor much of the market. Urgent care, oncology, and gerontology specialties see particularly steady openings as the state's aging population and underserved rural communities drive sustained need at every experience level. See the openings below and apply to the ones that match your experience.
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Showing 5 of 81+ Nurse Practitioner jobs
At Armor Health we are raising the standard of care to impact the lives of those we serve by partnering with exceptional correctional organizations to improve health care outcomes. We provide support for patients and foster the holistic wellness and well-being of the lives entrusted in our care. Armor is laser-focused on providing the best-in-class interventions to ensure optimal outcomes. Through our core values of embracing change, taking ownership, attention to detail, a sense of urgency, and a results oriented collaborative environment, we are a dynamic team that is transforming and revolutionizing correctional healthcare.
Great outcomes start with great people and Armor has an exciting opportunity for a Psychiatric Nurse Practitioner to join our team at Richland Prison in Columbia, South Carolina.
- Performs psychiatric examinations and evaluations, diagnoses, treatment, follow-up consultation and health education
- Works closely with the BHD and/or BHPs in identifying appropriate treatment plans for at-risk patients, or as needed
- Intermittently attends morning huddle calls, when indicated and/or when there are high-risk patients that require multidisciplinary treatment planning and collaboration
- Obtains patient histories, follows up with medication verification efforts, reviews pertinent medical history and develops patient care treatment plans, ensuring completeness and accuracy using the POMR format
- Provides support in coordinating the activities of patient care and/or support staff
- Participates in developing specific mental health policies and procedures, when indicated
- Current state license as a Psychiatric Nurse Practitioner
- Current CPR certificate
- Two (2) years of experience in psychiatric and/or correctional healthcare setting
- Proficient with electronic medical records
- Ability to pass pre-employment Level 2 clearance to include background check and drug screen
Armor Health offers career development opportunities, competitive salaries, and an excellent benefit package that includes:
- Excellent medical, dental, and vision insurance options
- Paid time off
- 401(k) retirement plan
- Short and long term disability insurance
- Much more!
If you want to join an exciting, dynamic and growing organization that is making a positive impact on the lives we serve, we look forward to considering you for this opportunity and to be part of our team!
Armor Health is committed to providing equal employment opportunity for all qualified employees and applicants. We comply with all applicable federal and state laws prohibiting discrimination in employment, including but not limited to those that prohibit discrimination based on color, religion, sex, pregnancy, sexual orientation, genetic information, national origin, immigration status, age, physical or mental disability, military or veteran's status, and citizenship.
At Armor Health we are raising the standard of care to impact the lives of those we serve by partnering with exceptional correctional organizations to improve health care outcomes. We provide support for patients and foster the holistic wellness and well-being of the lives entrusted in our care. Armor is laser-focused on providing the best-in-class interventions to ensure optimal outcomes. Through our core values of embracing change, taking ownership, attention to detail, a sense of urgency, and a results oriented collaborative environment, we are a dynamic team that is transforming and revolutionizing correctional healthcare.
Great outcomes start with great people and Armor has an exciting opportunity for a Psychiatric Nurse Practitioner to join our team at Richland Prison in Columbia, South Carolina.
- Performs psychiatric examinations and evaluations, diagnoses, treatment, follow-up consultation and health education
- Works closely with the BHD and/or BHPs in identifying appropriate treatment plans for at-risk patients, or as needed
- Intermittently attends morning huddle calls, when indicated and/or when there are high-risk patients that require multidisciplinary treatment planning and collaboration
- Obtains patient histories, follows up with medication verification efforts, reviews pertinent medical history and develops patient care treatment plans, ensuring completeness and accuracy using the POMR format
- Provides support in coordinating the activities of patient care and/or support staff
- Participates in developing specific mental health policies and procedures, when indicated
- Current state license as a Psychiatric Nurse Practitioner
- Current CPR certificate
- Two (2) years of experience in psychiatric and/or correctional healthcare setting
- Proficient with electronic medical records
- Ability to pass pre-employment Level 2 clearance to include background check and drug screen
Armor Health offers career development opportunities, competitive salaries, and an excellent benefit package that includes:
- Excellent medical, dental, and vision insurance options
- Paid time off
- 401(k) retirement plan
- Short and long term disability insurance
- Much more!
If you want to join an exciting, dynamic and growing organization that is making a positive impact on the lives we serve, we look forward to considering you for this opportunity and to be part of our team!
Armor Health is committed to providing equal employment opportunity for all qualified employees and applicants. We comply with all applicable federal and state laws prohibiting discrimination in employment, including but not limited to those that prohibit discrimination based on color, religion, sex, pregnancy, sexual orientation, genetic information, national origin, immigration status, age, physical or mental disability, military or veteran's status, and citizenship.
See All 81 Nurse Practitioner Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Nurse Practitioner JobsNurse Practitioner Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Nurse Practitioner Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Prisma Health Urgent Care12P
- Your Health Organization9
- CVS Health3
- PruittHealth3
- Lowcountry Urgent Care3
Top Industries Hiring
- Insurance
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in nurse practitioner jobs across South Carolina.
- Active nurse practitioner license issued or recognized by the South Carolina Board of Nursing
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- National board certification as a nurse practitioner from ANCC or AANP
- Current DEA registration and prescriptive authority under South Carolina collaborative practice requirements
- Minimum one to three years of clinical experience in a relevant specialty area
- Current BLS and ACLS certification required for hospital and acute care settings
Nurse Practitioner Jobs in South Carolina: Frequently Asked Questions
How do you become a nurse practitioner in South Carolina?
You must hold an active advanced practice registered nurse license issued by the South Carolina Board of Nursing, which requires completing an accredited graduate-level nurse practitioner program and passing a national certification exam through ANCC or AANP. South Carolina also requires nurse practitioners to maintain a collaborative practice agreement with a physician for prescriptive authority. Applications are submitted directly to the South Carolina Board of Nursing, which oversees all APRN licensure in the state.
How much do nurse practitioners make in South Carolina?
Nurse practitioners in South Carolina earn a median of about $123,290 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $97,080 for the lowest 10% to over $160,170 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire nurse practitioners in South Carolina?
Companies currently hiring nurse practitioners in South Carolina include Prisma Health Urgent Care, Your Health Organization, and CVS Health, per current listings on Migrate Mate as of October 2026. Large integrated health systems such as Prisma Health and MUSC Health represent a significant share of ongoing openings across the state.
Which South Carolina cities have the most nurse practitioner jobs?
Columbia, Anderson, and Charleston have the most nurse practitioner openings in South Carolina. Columbia and Greenville lead because of their large hospital systems and growing outpatient clinic networks, while Charleston's concentration of academic medical centers and specialty practices, anchored by MUSC Health, drives strong demand there as well.
Are there remote nurse practitioner jobs in South Carolina?
Yes, but they're rare. About 42% of nurse practitioner openings tied to South Carolina are remote or hybrid as of October 2026, reflecting how hands-on patient care limits fully remote arrangements. The roles most likely to offer remote or telehealth components are psychiatric and behavioral health positions, where virtual visits have become a standard part of practice in South Carolina.
How can I get hired as a nurse practitioner in South Carolina with little or no experience?
The most realistic entry path is applying for new-graduate nurse practitioner residency or fellowship programs, which Prisma Health and MUSC Health both offer for candidates transitioning from RN roles into advanced practice. Working as a registered nurse in a specialty you intend to practice in, such as family medicine or psychiatry, strengthens your application and satisfies the clinical familiarity many South Carolina employers expect. Completing your national board certification promptly after graduation and securing your South Carolina APRN license before applying gives you a clear edge over candidates still awaiting credentials.
Where can I find and apply to nurse practitioner jobs in South Carolina?
You can find and apply to nurse practitioner jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings for roles that match your specialty and experience level, then apply directly to the positions that fit.
See All 81 Nurse Practitioner Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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