Case Manager Jobs in South Carolina
Case Manager jobs in South Carolina are in strong demand, with active hiring concentrated in healthcare, behavioral health, and social services across a workforce that ranges from entry-level coordinators to senior clinical case managers. Columbia, Greenville, and Charleston are the busiest hiring markets, anchored by large employers such as Prisma Health, MUSC Health, and BlueCross BlueShield of South Carolina. The most consistent openings are in mental health and substance use case management, Medicaid and managed care coordination, and hospital discharge planning. See the openings below and apply to the ones that match your experience.
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Are you a compassionate Registered Nurse (RN) who finds purpose in supporting patients and families through meaningful moments of care? Crescent Hospice is seeking a Full Time Hospice RN Case Manager (RNCM) to join our dedicated nursing team providing exceptional end-of-life care throughout the community.
Schedule: Monday - Friday, 8 am - 4:30 pm
In this rewarding role, you’ll deliver hands-on hospice nursing care, coordinate services, and guide patients and families through every step of their hospice journey. As a valued member of our interdisciplinary care team, you’ll help ensure every patient receives The Best Care Possible — care grounded in compassion, clinical excellence, and connection.
Who we are:
We offer a supportive, growth-oriented environment along with a comprehensive benefits package that includes:
- Comprehensive Health, Dental, & Vision Insurance
- Career Path Program that supports internal growth, advancement, and increased pay
- A generous time-off package with 15 days of PTO & 10 Holidays to rest and recharge
- Tuition Reimbursement & Certification Assistance to support your professional growth
- Wellness & Discount Programs to help you lead a healthy and balanced life
- Cell Phone, Mileage, & Gym Membership Reimbursement for your convenience
- Company matching 401(k) to secure your future
- Hands-on Clinical Onboarding Program to ensure you have a smooth transition into our team
- Empower Through Engagement: Respond to clinical referral information with care and expertise, addressing inquiries and requests with a compassionate touch that showcases our commitment to exceptional service.
- Collaborative Care Champion: Partner closely with our Clinical Director to assess the eligibility and suitability of clients for our specialized hospice services. Your expertise will guide us in providing the right care, at the right time.
- Nurturing Direct Care: As an RN Case Manager, you're not just coordinating care – you're a source of comfort and support for patients, ensuring their comfort and quality of life remain paramount.
- Nursing with Heart: Apply your nursing skills by delivering top-notch care rooted in proven principles and techniques. Your dedication will help ease pain and bring solace to those under our care.
- Educator and Advocate: Empower patients and families through education, encouraging their active participation in creating personalized care plans that align with their goals.
- Call of Compassion: Join our team in sharing the responsibility of call duties. These moments are a testament to our commitment to being there when it matters most.
- Hold current unencumbered license as a Registered Nurse.
- Minimum one (1) year experience as an RN in a medical surgical/acute care setting. Hospice exp a plus!
- Must be computer proficient in typing and various programs, including background in EMR.
- Possess and maintains current CPR certification if required by state.
- Current driver's license, vehicle insurance, and access to dependable transportation.
See All 52 Case Manager Jobs in South Carolina
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Find Case Manager JobsCase Manager Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Case Manager Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Insurance
What South Carolina Employers Look For
The qualifications that appear most often in case manager jobs across South Carolina.
- Active South Carolina social work license (LSW or LMSW) or equivalent licensure recognized in South Carolina
- Bachelor's degree in social work, psychology, nursing, or a related human services field
- Experience with care coordination, discharge planning, or Medicaid managed care programs
- Proficiency in electronic health records and case management documentation systems
- Strong knowledge of South Carolina community resources, referral networks, and support services
- Certification such as CCM, ACM, or CDMS preferred for clinical and managed care positions
Case Manager Jobs in South Carolina: Frequently Asked Questions
How do you become a case manager in South Carolina?
Most case manager roles in South Carolina require at minimum a bachelor's degree in social work, nursing, psychology, or a related field, and clinical positions typically require licensure through the South Carolina Board of Social Work Examiners as a Licensed Social Worker or Licensed Master Social Worker. Healthcare-based case managers may also pursue nationally recognized credentials such as the Certified Case Manager designation. Employers in managed care and hospital settings commonly expect prior experience in care coordination, discharge planning, or community health alongside any required licensure.
Which companies hire case managers in South Carolina?
Companies currently hiring case managers in South Carolina include State of South Carolina, Your Health Organization, and TRISTAR, per current listings on Migrate Mate as of October 2026. South Carolina's largest health systems, managed Medicaid contractors, and behavioral health organizations represent the most consistent sources of full-time case manager openings across the state.
Which South Carolina cities have the most case manager jobs?
Charleston, North Charleston, and Columbia lead South Carolina for case manager openings. Columbia drives volume as the state capital and home to major health systems and state agency offices, Greenville's growing Upstate healthcare corridor anchors demand there, and Charleston's concentration of hospital networks and behavioral health providers supports strong hiring along the coast.
Are there remote case manager jobs in South Carolina?
Yes, but they're less common than in purely desk-based fields. About 33% of case manager openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the fact that many positions require in-person client contact, home visits, or facility-based coordination. Managed care, utilization review, and telephonic case management roles are the segments most likely to offer fully remote arrangements.
How can I get hired as a case manager in South Carolina with little or no experience?
The most realistic entry path is a case management assistant or care coordinator role at a South Carolina hospital system or managed care organization, which routinely hire candidates with a relevant bachelor's degree but limited direct experience. Prisma Health and MUSC Health both post associate-level care coordination positions suited to new graduates. Lateral moves from adjacent roles such as medical social work intern, community health worker, or patient navigator also open the door, and completing a field placement or practicum through a South Carolina accredited social work program strengthens any application considerably.
Where can I find and apply to case manager jobs in South Carolina?
You can find and apply to case manager jobs in South Carolina on Migrate Mate, which lists current openings from employers hiring across the state. Search the listings to find roles that fit your experience, credentials, and preferred location, then apply directly to the ones that match.
See All 52 Case Manager Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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