Nurse Practitioner Jobs in San Antonio, TX

Nurse Practitioner jobs in San Antonio are in strong demand, with openings concentrated in the South Texas Medical Center, downtown, and the Stone Oak corridor across health systems, federally qualified health centers, and military-affiliated clinics. Employers hiring right now include Nexus Health Systems, HealthTexas Medical, and Methodist Healthcare System. See the openings below and apply to the ones that match your experience.

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Overview

Open roles270+
Top employerNexus Health Systems
Work type100% On-site
Top credentialManaged care
Companies hiring15

Showing 5 of 270+ Nurse Practitioner jobs

Psychiatric Nurse Practitioner (PMHNP)
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Added 4d ago
Psychiatric Nurse Practitioner (PMHNP)
Serenity Healthcare
San Antonio, Texas
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
501-1,000

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Psychiatric Advanced Nurse Practitioner
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Added 5d ago
Psychiatric Advanced Nurse Practitioner
Texas Health and Human Services Commission
San Antonio, Texas
Mental & Behavioral Health
Nursing
Patient Services & Wellbeing
$12k - $14k/yr
Master's degree
10,000+

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Pediatric Nurse Practitioner
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Added 5d ago
Pediatric Nurse Practitioner
Healthbound 365
San Antonio, Texas
Healthcare Administration
Nursing
Patient Services & Wellbeing
$85k - $200k/yr
On-Site

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Nurse Practitioner / Physician Assistant - GYN Oncology
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Added 6d ago
Nurse Practitioner / Physician Assistant - GYN Oncology
University Health
San Antonio, Texas
Allied Health
Clinical Support
Healthcare Administration
$52.88 - $79.33/hr
10,000+

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Family Nurse Practitioner - Val Verde
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Added 6d ago
Family Nurse Practitioner - Val Verde
HealthTexas Medical Group
San Antonio, Texas
Healthcare Administration
Nursing
Patient Services & Wellbeing
Managed care

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Nurse Practitioner Job Market in San Antonio

Who's Hiring

  • Nexus Health Systems30
  • HealthTexas Medical30
  • Methodist Healthcare System30
  • Optum15
  • Endeavors15

Top Industries Hiring

  • Insurance
  • Healthcare & Medical Services

Nurse Practitioner Jobs in San Antonio: Frequently Asked Questions

How do I get a nurse practitioner job in San Antonio?

The strongest hiring in San Antonio comes from the South Texas Medical Center complex, large regional health systems, federally qualified health centers serving the city's underserved communities, and military-connected facilities near Joint Base San Antonio. Candidates with experience in primary care, family medicine, or psychiatry tend to move fastest. Bilingual Spanish proficiency is a genuine competitive advantage in a city where a large share of patients speak Spanish as their primary language.

Which companies hire nurse practitioners in San Antonio?

San Antonio nurse practitioner roles are posted by Nexus Health Systems, HealthTexas Medical, and Methodist Healthcare System and others right now, based on current listings on Migrate Mate as of October 2026. The local market is anchored by large nonprofit health systems, federally qualified health centers, and military-affiliated healthcare organizations that collectively drive a consistent share of openings year-round.

Are there remote nurse practitioner jobs in San Antonio?

Yes, but only for a narrow slice of the role, since most nurse practitioner positions require direct patient care on-site. About 0% of nurse practitioner openings tied to San Antonio are remote or hybrid as of October 2026, and those positions tend to cluster in telehealth, utilization review, and case management functions where patient interaction happens through virtual platforms rather than in a clinic.

How can I get a nurse practitioner job in San Antonio with little or no experience?

The most realistic entry path in San Antonio is through federally qualified health centers and community health clinics, which regularly hire new graduates and often offer loan repayment incentives tied to underserved-area service. Military-affiliated facilities near Joint Base San Antonio also run structured onboarding programs suited to early-career NPs. Completing clinical rotations with San Antonio health systems beforehand builds familiarity with local protocols and gives hiring managers a reason to reach back out when a position opens.

Which industries hire the most nurse practitioners in San Antonio?

Most nurse practitioner openings in San Antonio sit in Insurance and Healthcare & Medical Services, per current listings on Migrate Mate as of October 2026. San Antonio's concentration of military personnel, veterans, and a large uninsured population creates sustained demand across health systems, community clinics, and government-affiliated healthcare programs that other Texas cities don't replicate at the same scale.

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