Nurse Practitioner Jobs in San Antonio, TX
Nurse Practitioner jobs in San Antonio are in strong demand, with openings concentrated in the South Texas Medical Center, downtown, and the Stone Oak corridor across health systems, federally qualified health centers, and military-affiliated clinics. Employers hiring right now include Nexus Health Systems, HealthTexas Medical, and Methodist Healthcare System. See the openings below and apply to the ones that match your experience.
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Psychiatric Nurse Practitioner (PMHNP)
Tired of being treated like a cog in a large corporate health system? Exhausted by the amount of time you spend with administrative work and fighting with insurance companies? Would you like to spend more time focused on helping your patients heal? If you answer yes to any of these questions, then you need to join Serenity Healthcare!
Who we are:
- Serenity Healthcare is the largest, fastest growing physician owned interventional psychiatry practice in the US.
- Since we’re physician owned and operated, we work to remove administrative tasks from our providers so you can focus 100% on patient care.
- We provide best in industry outcomes for our patients utilizing interventional treatment options like TMS and ketamine infusion therapy.
- We take care of our PMHNPs by offering quarterly events and annual retreats to locations like the Bahamas and Hawaii.
What we offer:
- Paid training to become Brainsway Deep TMS certified
- Salary of $150,000 annually, plus incentives
- Amazing clinical support = 8:1 staff to provider ratio
- 90% paid premiums for medical benefits for the whole family
- 33 days of paid time off annually
- Outpatient only with zero call responsibility
- Great schedule = 3 13-hour shifts weekly
If the information above sounds interesting, we would love to speak with you to share more details about our clinical results and superior operational support.
Now is your chance to join a company that will support you, so you can support your patients! Please click apply so we can schedule a time to speak with you.
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Find Nurse Practitioner JobsNurse Practitioner Job Market in San Antonio
Who's Hiring
- Nexus Health Systems30

- HealthTexas Medical30H
- Methodist Healthcare System30

- Optum15

- Endeavors15

Top Industries Hiring
- Insurance
- Healthcare & Medical Services
Nurse Practitioner Jobs in San Antonio: Frequently Asked Questions
How do I get a nurse practitioner job in San Antonio?
The strongest hiring in San Antonio comes from the South Texas Medical Center complex, large regional health systems, federally qualified health centers serving the city's underserved communities, and military-connected facilities near Joint Base San Antonio. Candidates with experience in primary care, family medicine, or psychiatry tend to move fastest. Bilingual Spanish proficiency is a genuine competitive advantage in a city where a large share of patients speak Spanish as their primary language.
Which companies hire nurse practitioners in San Antonio?
San Antonio nurse practitioner roles are posted by Nexus Health Systems, HealthTexas Medical, and Methodist Healthcare System and others right now, based on current listings on Migrate Mate as of October 2026. The local market is anchored by large nonprofit health systems, federally qualified health centers, and military-affiliated healthcare organizations that collectively drive a consistent share of openings year-round.
Are there remote nurse practitioner jobs in San Antonio?
Yes, but only for a narrow slice of the role, since most nurse practitioner positions require direct patient care on-site. About 0% of nurse practitioner openings tied to San Antonio are remote or hybrid as of October 2026, and those positions tend to cluster in telehealth, utilization review, and case management functions where patient interaction happens through virtual platforms rather than in a clinic.
How can I get a nurse practitioner job in San Antonio with little or no experience?
The most realistic entry path in San Antonio is through federally qualified health centers and community health clinics, which regularly hire new graduates and often offer loan repayment incentives tied to underserved-area service. Military-affiliated facilities near Joint Base San Antonio also run structured onboarding programs suited to early-career NPs. Completing clinical rotations with San Antonio health systems beforehand builds familiarity with local protocols and gives hiring managers a reason to reach back out when a position opens.
Which industries hire the most nurse practitioners in San Antonio?
Most nurse practitioner openings in San Antonio sit in Insurance and Healthcare & Medical Services, per current listings on Migrate Mate as of October 2026. San Antonio's concentration of military personnel, veterans, and a large uninsured population creates sustained demand across health systems, community clinics, and government-affiliated healthcare programs that other Texas cities don't replicate at the same scale.
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