Nursing Jobs in St. Louis, MO

Nursing jobs in St. Louis draw strong demand from health systems and specialty clinics concentrated in the Central West End, Cortex Innovation District, and South Grand corridor, with the city's academic medical centers and long-term care networks among the most active employers. Employers hiring right now include Mercy, SSM Health, and Luxor Healthcare. See the openings below and apply to the ones that match your experience.

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Overview

Open roles38
Top employerMercy
Work type78% On-site
Top credentialManaged Registered Nurses (RNs)
Companies hiring18

Showing 5 of 38+ Nursing jobs

SSM Health
Regional Vice President of Patient Care Services / Regional Chief Nursing Officer
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SSM Health
New 1m ago
Regional Vice President of Patient Care Services / Regional Chief Nursing Officer
SSM Health
St. Louis, Missouri
IT Support
Project Management
Technical Program Management
On-Site
Managed Registered Nurses (RNs)
10,000+

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SSM Health
Registered Nurse Program Manager - Nursing Administration
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SSM Health
New 1m ago
Registered Nurse Program Manager - Nursing Administration
SSM Health
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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KVC Health Systems
Nursing Supervisor
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KVC Health Systems
New 1m ago
Nursing Supervisor
KVC Health Systems
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
Managed Registered Nurses (RNs)
1,001-5,000

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Altea Healthcare
Operations Manager-Post Acute Skilled Nursing
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Altea Healthcare
New 1m ago
Operations Manager-Post Acute Skilled Nursing
Altea Healthcare
St. Louis, Missouri
Business Development
Customer Success
Program Management
Project Management
Hybrid
Bachelor's degree
201-500

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Beauvais Manor Rehabilitation and Health Center
Assistant Director of Nursing
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Beauvais Manor Rehabilitation and Health Center
New 1m ago
Assistant Director of Nursing
Beauvais Manor Rehabilitation and Health Center
St. Louis, Missouri
Healthcare Administration
Human Resources
Nursing
Managed Registered Nurses (RNs)

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Nursing Job Market in St. Louis

Who's Hiring

  • Mercy
    Mercy11
  • SSM Health
    SSM Health4
  • Luxor Healthcare
    Luxor Healthcare4
  • Reliant Care Management Company
    Reliant Care Management Company4
  • Kindred Hospitals
    Kindred Hospitals2

Top Industries Hiring

  • Healthcare & Medical Services14
  • Education1

Nursing Jobs in St. Louis: Frequently Asked Questions

How do I get a nursing job in St. Louis?

Start by targeting St. Louis's largest hiring sectors: academic medical centers, large regional health systems, and the growing network of outpatient specialty clinics in the Central West End and Midtown corridors. Candidates with experience in critical care, med-surg, or oncology have a consistent edge given the concentration of cancer and cardiac programs here. Applying directly to health system career portals and following up through unit nurse managers tends to move faster than applying through general boards.

Which companies hire nursings in St. Louis?

Employers hiring nursings in St. Louis right now include Mercy, SSM Health, and Luxor Healthcare, based on current listings on Migrate Mate as of July 2026. St. Louis draws hiring from a mix of large nonprofit health systems, for-profit hospital groups, and specialty ambulatory surgery centers spread across the metro.

Are there remote nursing jobs in St. Louis?

Yes, though remote nursing roles are limited by nature since most positions require direct patient care. About 22% of nursing openings tied to St. Louis are remote or hybrid as of July 2026, covering roles where this is feasible. In St. Louis, remote opportunities concentrate in utilization review, case management, telehealth triage, and insurance authorization roles connected to the city's large managed care and payer organizations.

How can I get a nursing job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is a new graduate residency program offered by the city's major health systems, which provide structured clinical mentorship for RNs entering their first role. Entry-level candidates also find traction in long-term care facilities and skilled nursing communities across South City and the inner suburbs, where hiring volume is high and competition is lower than in acute care. Completing a clinical rotation at a local facility and converting that relationship into an offer is a proven route here.

Which industries hire the most nursings in St. Louis?

Most nursing openings in St. Louis sit in Healthcare & Medical Services and Education, per current listings on Migrate Mate as of July 2026. St. Louis's identity as a regional medical hub, anchored by its cluster of academic hospitals, rehabilitation centers, and specialty research institutions, drives consistent demand across those sectors year-round.

See All 38 Nursing Jobs in St. Louis

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