Pharmacy Manager Jobs in Massachusetts
Pharmacy Manager jobs in Massachusetts are consistently active across the state's dense network of retail pharmacy chains, academic medical center outpatient pharmacies, and integrated health system locations, with openings at every level from newly licensed pharmacist-in-charge candidates through experienced multi-site directors. Boston, Worcester, and Springfield anchor the largest share of hiring, with major employers like CVS Health, Mass General Brigham, and Walgreens maintaining ongoing pharmacy manager needs throughout the state. Specialty areas seeing the strongest demand include clinical pharmacy management, specialty and oncology pharmacy oversight, and long-term care pharmacy operations. Find a role that fits below and apply directly.
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Pharmacy Manager, 340B Program
Location: Hybrid schedule, physically located at Tufts Medical Center, system-level compliance responsibilities for both Tufts Medical Center and Lowell General Hospital
Job Description
Minimum Qualifications:
- Bachelor’s degree in Pharmacy.
- Pharmacist License.
- Five (5) years of hospital pharmacy experience including supervisory responsibilities.
Preferred Qualifications:
- PharmD.
- Completion of a general pharmacy residency and a specialty residency.
- Eight (8) years of hospital pharmacy experience including supervisory responsibilities.
- Experience in drug utilization review and analysis.
- Experience with Electronic Medical Records.
General Description and Goals
The 340B Program Manager is a member of the Department of Pharmacy's Leadership Team at Tufts Medical Center, with primary responsibility for assuring system-wide compliance with the 340B Drug Pricing Program and oversight of Contract Pharmacy agreements across both acute care and ambulatory settings at Tufts Medical Center and Lowell General Hospital. This role serves as the subject matter expert within the Department of Pharmacy and as the 340B Oversight Committee chair and liaison with Contract Pharmacy and third-party administrator representatives.
The Program Manager provides leadership for the development, implementation, and maintenance of policies and guidelines pertaining to the 340B Program, and maintains a broad-based, current knowledge of 340B regulations to safeguard ongoing, organization-wide compliance. The role includes delivering 340B education to Tufts Medicine employees on a yearly basis and serving as the go-to resource for all 340B-related issues, in coordination with pharmacy, compliance, legal, and finance stakeholders.
Responsibilities Include:
Program Leadership & Committee Oversight
- Serve as the coordinator and leader of the 340B Oversight Committee, which includes members from senior leadership, pharmacy, compliance, legal, government affairs, reimbursement, supply chain, and finance.
- Organize and lead weekly 340B meetings and quarterly 340B Oversight Committee meetings.
- Serve as the primary program liaison and 340B compliance expert for the Department of Pharmacy, connecting with affiliated departments to ensure program integrity.
- Actively engage with senior leadership and participate in decision-making related to the implementation of new 340B processes and initiatives.
Policy & Procedure Development
- Provide leadership for implementing and maintaining policies and guidelines pertaining to the 340B Program.
- Evaluate and document changes to 340B regulations; update policies and procedures to maintain ongoing compliance.
- Ensure policies and procedures are developed, approved by Legal, and maintained in accordance with organizational, state, and federal requirements, without creating unnecessary operational cost or burden.
Regulatory Monitoring & HRSA Registration
- Maintain a broad-based, current knowledge of 340B regulations to maintain system-wide compliance.
- Assure that information on the HRSA website (OPAIS) is correct, and notify the primary contact and authorizing official of any changes needed.
- Monitor 340B guidance and rule changes — including HRSA/OPA rules and Medicaid updates — and attend 340B trainings, sharing key updates and hot topics with staff.
- Ensure the annual HRSA recertification and registration of any new child sites are completed within the required time frame.
Auditing & Compliance Monitoring
- Assure claim audits are completed in a timely manner.
- Develop, execute, and document self-audits of the 340B process, and coordinate remediation of any findings.
- Conduct or coordinate annual audits of all contract pharmacies and monthly audits of 340B-eligible locations to verify adherence to program guidelines.
- Serve as the point person for external and independent audits, coordinating all requests and responses and maintaining a continual state of audit readiness.
- Evaluate patient eligibility for qualified and non-qualified patients across mixed-use, outpatient, and contract pharmacy settings by reviewing medical records, insurance plans, and hospital status.
Contract Pharmacy Management
- Review the financial performance of Contract Pharmacy agreements and recommend or implement changes as needed.
- Manage relationships, billing services, and compliance with contracted 340B pharmacies.
- Review and negotiate new 340B contracts and maintain all existing contract pharmacy agreements.
- Evaluate current and prospective contract pharmacy opportunities, including contract language, fee structure, data setup, and auditing requirements.
- Manage data reporting requirements through 340B ESP and other manufacturer mandated platforms to maintain access to 340B pricing.
Purchasing & Inventory Oversight
- Ensure the 340B crosswalk and accumulations are continually reviewed and updated.
- Work closely with the Procurement team to ensure proper purchasing practices are followed for all pharmaceuticals.
- Monitor purchasing records, utilization, and 340B purchasing accounts to ensure tools and software are working properly and to identify savings opportunities or discrepancies.
- Oversee 340B regulatory aspects of the inventory purchasing process across outpatient, inpatient, and mixed-use areas.
Split-Billing / Third-Party Administrator Software
- Maintain the integrity of the 340B split-billing software and review applicable reports to identify areas for improvement.
- Integrate pharmacy chargemaster data into the 340B split-billing system to support auditable, compliant processes.
- Coordinate with outpatient pharmacy and pharmacy informatics teams on electronic interfaces between the EMR, the virtual accumulator, and contract pharmacy providers/administrators.
Reporting
- Report monthly financial performance of the Contract Pharmacy program to the Director of Pharmacy Business Operations.
- Assure all 340B reporting is completed in accordance with policy and regulatory requirements.
- Develop and present routine reports on 340B utilization, savings, problem areas, and discrepancies to pharmacy and administrative leadership.
Education & Precepting
- Provide 340B education for all Tufts Medicine employees on a yearly basis, as required.
- Precept PGY2 residents in the Health-System Pharmacy Administration and Leadership program at TMC.
- Develop training and competency materials for staff involved in the 340B Program.
Quality & Regulatory Standards
- Ensure ongoing compliance with quality and regulatory standards related to the 340B Program.
- Collaborate with Tufts Medicine government affairs, legal, and external legal counsel to address changes or concerns including advocacy at a state and federal level.
Physical Requirements:
- Frequent standing & walking, and lifting of 5-10 lbs.
- May require lifting and carrying light loads, including boxes, equipment, and stooping or kneeling.
- Requires manual dexterity using fine hand manipulation to operate prescription medications and computer keyboard.
- Requires ability to see medications, computer screen and reports.
Skills & Abilities:
- Ability to work independently with minimal supervision and as part of a team.
- Superior verbal and written presentation skills.
- Superior communication skills, including developing and giving presentations, both 1-1 and group.
- Knowledge of integrated health networks.
- Knowledge of health plan drug formularies.
- Project and resource management skills.
- Creative thinking and problem-solving skills.
- Ability to understand the importance of and respect for the confidentiality of all patient information in accordance with applicable standards and regulations.
- Knowledge of clinical best practices and standards for optimizing medication use.
- Proficiency in Microsoft Office applications, including Access, Excel, PowerPoint and Word.
- Ability to work with all ages, backgrounds, ethnicities, and life experiences.
- A robust understanding of chronic health condition management and population management.
- Motivational Interviewing proficiency.
- Ability to prioritize and resolve critical issues efficiently and effectively.
- Detail oriented, with strong organizational skills and multi-tasking abilities.
- Very strong working knowledge and proficiency with technology and business software (Microsoft Office).
- Willingness and ability to learn and utilize new technology and procedures that will continue to develop in their role and throughout the organization.
Job Profile Summary
This role focuses on providing pharmacy related services in a hospital or retail setting. In addition, this role focuses on performing the following Pharmacy Leadership duties: Controls, directs, and participates in the activities of the organization through a hierarchy of managers and supervisors. Responsibilities also include long-term strategic planning, determining the policies of the organization, and allocating its resources and making decisions regarding organization growth and diversification to accomplish entity's vision. A management role that supervises employees focusing on tactical, operational activities within a specified area, with the majority of time spent overseeing area of responsibility, planning, prioritizing and/or directing the responsibilities of employees. Goal achievement is typically accomplished through performance of direct and/or indirect reports. A role that manages experienced professionals who exercise latitude and independence in assignments. Responsibilities typically include: policy and strategy implementation for short-term results (1 year or less), problems faced are difficult to moderately complex, and influences others outside of own job area regarding policies, practices and procedures.
Job Overview
This position works closely with other health practitioners to meet the various needs of our patients. Improves the health of patients by providing pharmaceutical care to individual patients and by coordinating the procurement, storage, preparation, and distribution of drugs to all patients. Provides leadership by facilitating the development, implementation, and maintenance of hospital and departmental systems that promote desirable patient outcomes. Educates students, interns, residents, nurses, and patients and participates in interdepartmental committees. Reviews and approves medication orders, monitors drug therapies, and provides drug information.
At Tufts Medicine, we want every individual to feel valued for the skills and experience they bring. Our compensation philosophy is designed to offer fair, competitive pay that attracts, retains, and motivates highly talented individuals, while rewarding the important work you do every day.
The base pay ranges reflect the minimum qualifications for the role. Individual offers are determined using a comprehensive approach that considers relevant experience, certifications, education, skills, and internal equity to ensure compensation is fair, consistent, and aligned with our business goals.
Beyond base pay, Tufts Medicine provides a comprehensive Total Rewards package that supports your health, financial security, and career growth—one of the many ways we invest in you so you can thrive both at work and outside of it.
Pay Range:
$147,995.12 - $188,688.50based on full-time equivalent
See All 65 Pharmacy Manager Jobs in Massachusetts
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Find Pharmacy Manager JobsPharmacy Manager Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Pharmacy Manager Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Walgreens24

- CVS Health14

- Boston Medical Center3

- Dana-Farber Cancer Institute3

- Amazon2

Top Industries Hiring
- Insurance
- Retail
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
What Massachusetts Employers Look For
The qualifications that appear most often in pharmacy manager jobs across Massachusetts.
- Active Massachusetts pharmacist license issued by the Board of Registration in Pharmacy
- Doctor of Pharmacy degree from an ACPE-accredited college of pharmacy
- Minimum two years of retail or clinical pharmacy supervisory experience
- Demonstrated ability to manage pharmacy staff, schedules, and performance reviews
- Experience with pharmacy management software and PBM reconciliation workflows
- Strong working knowledge of Massachusetts DEA controlled substance regulations and compliance
Pharmacy Manager Jobs in Massachusetts: Frequently Asked Questions
How do you become a pharmacy manager in Massachusetts?
Becoming a pharmacy manager in Massachusetts requires an active pharmacist license issued by the Massachusetts Board of Registration in Pharmacy, which you obtain by earning a Doctor of Pharmacy degree, completing an ACPE-accredited program, and passing the NAPLEX and MPJE licensing exams. Employers typically expect at least two years of practice experience before promoting into a manager role, and many large Massachusetts health systems require proof of continuing education compliance.
Which companies hire pharmacy managers in Massachusetts?
Employers hiring pharmacy managers in Massachusetts right now include Walgreens, CVS Health, and Boston Medical Center, based on current listings on Migrate Mate as of October 2026. Massachusetts's concentration of major health systems and one of the highest retail pharmacy densities in the Northeast means openings appear regularly at both chain and hospital-affiliated locations throughout the state.
Which Massachusetts cities have the most pharmacy manager jobs?
Boston, Brockton, and Westwood have the most pharmacy manager openings in Massachusetts right now. Boston's concentration of academic medical centers and flagship retail locations drives the bulk of demand, while Worcester's regional hospital network and Springfield's role as the commercial hub of western Massachusetts generate consistent hiring for both retail and institutional pharmacy manager roles in those markets.
Are there remote pharmacy manager jobs in Massachusetts?
Yes, but they're rare. About 25% of pharmacy manager openings tied to Massachusetts are remote or hybrid as of October 2026, reflecting that most pharmacy manager roles require on-site presence to supervise staff, manage controlled substances, and maintain state compliance. The portions most likely to be performed remotely are administrative functions such as scheduling, reporting, and vendor coordination for managers overseeing multiple locations.
How can I get hired as a pharmacy manager in Massachusetts with little or no experience?
The most realistic entry path is to secure a staff pharmacist role at a Massachusetts health system or retail chain and pursue an internal promotion track. Large employers like Mass General Brigham and Beth Israel Deaconess run PGY-1 and PGY-2 pharmacy residency programs that explicitly develop candidates for clinical management roles. Gaining a Massachusetts pharmacist-in-charge designation on even a single location, along with a history of precepting students, signals readiness to hiring managers and distinguishes candidates who lack multi-year management titles.
Where can I find and apply to pharmacy manager jobs in Massachusetts?
You can find and apply to pharmacy manager jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings from employers hiring now. Search the available roles, find the ones that fit your background and location, and apply directly to each position.
See All 65 Pharmacy Manager Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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