Physician Assistant Jobs in San Antonio, TX
Physician Assistant jobs in San Antonio are concentrated in the South Texas Medical Center corridor, the Texas Medical Center affiliates along Fredericksburg Road, and growing suburban hubs in Stone Oak and the Loop 1604 corridor, across hospital systems, urgent care networks, and specialty clinics. Employers hiring right now include HealthTexas Medical, Optum, and Spine Clinic. Find a role that fits below and apply directly.
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Join our Team
The Pulmonary and Sleep Institute is seeking a dedicated and compassionate Nurse Practitioner or Physician Assistant to join our growing team and provide specialized care to patients with pulmonary and sleep-related conditions.
This is an exciting opportunity for an experienced NP or PA who is passionate about pulmonary and sleep medicine, patient education, and providing high-quality, evidence-based care. The ideal candidate will possess excellent clinical judgment, strong communication skills, and experience with pulmonary function testing (PFTs), respiratory medications/inhalers, Durable Medical Equipment (DME), and sleep therapy. Provider hired will only see established patients.
Key Responsibilities
Pulmonary Patient Care
- Evaluate and manage patients with acute and chronic pulmonary conditions, including asthma, COPD, chronic cough, shortness of breath, and other respiratory disorders.
- Conduct comprehensive patient evaluations, including medical histories and physical examinations.
- Order and interpret appropriate diagnostic testing, imaging, and laboratory studies.
- Review and interpret Pulmonary Function Tests (PFTs), including spirometry, lung volumes, and diffusion capacity (DLCO).
- Recognize obstructive, restrictive, and mixed ventilatory patterns and incorporate PFT findings into patient treatment plans.
- Provide ongoing pulmonary follow-up care and monitor patients’ response to treatment.
Respiratory Medication & Inhaler Management
- Possess strong knowledge of commonly prescribed pulmonary medications and inhaler therapies.
- Understand and appropriately manage rescue and maintenance inhalers, including SABA, LABA, LAMA, inhaled corticosteroids (ICS), and combination therapies.
- Assess medication effectiveness and make appropriate treatment recommendations based on symptoms, PFT results, and clinical findings.
- Educate patients on proper inhaler technique, medication adherence, and the appropriate use of rescue versus maintenance medications.
- Understand nebulizer therapy and other respiratory treatments commonly used in pulmonary medicine.
Sleep Medicine Patient Care
- Evaluate and manage patients with sleep-related conditions, including obstructive sleep apnea and other sleep disorders.
- Review sleep study results and assist in developing appropriate treatment plans.
- Manage patients receiving PAP therapy, including CPAP, BiPAP, and other prescribed sleep therapies.
- Review PAP compliance and therapy data and address barriers to successful treatment.
- Provide ongoing follow-up care and monitor patient response to sleep therapy.
- Have Inspire therapy knowledge.
Develop & Manage Treatment Plans
- Develop and implement individualized treatment plans using evidence-based medicine and current clinical practice guidelines.
- Adjust treatment plans based on patient progress, diagnostic testing, PFT findings, medication response, PAP compliance, symptoms, and clinical findings.
- Coordinate treatment recommendations with the supervising physician and clinical team.
DME & Sleep Therapy Management
- Knowledge and experience with Durable Medical Equipment (DME) is required.
- Understand PAP equipment, oxygen therapy, nebulizers, respiratory equipment, supplies, compliance requirements, and documentation necessary for DME services.
- Maintain appropriate documentation to support medical necessity and insurance requirements.
Patient & Family Education
- Educate patients and families regarding pulmonary and sleep disorders, treatment options, respiratory medications, inhaler technique, PAP therapy, equipment use, compliance, and overall health management.
- Provide counseling regarding lifestyle modifications and strategies that support successful pulmonary and sleep treatment.
- Encourage patient participation and adherence to treatment plans.
Documentation & Collaboration
- Maintain complete, accurate, and timely medical records.
- Document assessments, diagnoses, treatment plans, patient progress, and outcomes.
- Collaborate effectively with physicians, medical assistants, respiratory therapists, DME providers, sleep technicians, and other members of the healthcare team.
- Maintain compliance with HIPAA, organizational policies, and applicable clinical standards.
Required Qualifications
- Master of Science in Nursing (MSN) from an accredited Nurse Practitioner program.
- Current and unrestricted Nurse Practitioner/APRN license.
- Current DEA registration.
- Nurse Practitioner or Physician Assistant
- Minimum of 2 years of NP or PA experience.
- Experience in pulmonary and/or sleep medicine strongly preferred.
- Ability to review and interpret Pulmonary Function Tests (PFTs).
- Strong knowledge of pulmonary medications and inhaler therapies.
- Knowledge and experience with DME and PAP therapy is required.
- Strong clinical assessment and decision-making skills.
- Excellent written and verbal communication skills.
- Strong organizational and documentation skills.
- Ability to work independently while collaborating effectively within a physician-led healthcare team.
Preferred Experience
Previous experience in pulmonary medicine, sleep medicine, PFT interpretation, asthma/COPD management, respiratory medications, inhaler therapy, obstructive sleep apnea management, PAP therapy, oxygen therapy, or/and DME coordination is highly preferred.
Schedule
Monday - Thursday 7:30 am - 5:00 pm Friday 7:30 am - 12 pm
Pay: $116,000.00 - $121,000.00 per year
Benefits:
- Health insurance
- Paid time off
Work Location: In person
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Find Physician Assistant JobsPhysician Assistant Job Market in San Antonio
Who's Hiring
- HealthTexas Medical38H
- Optum25

- Spine Clinic13S
- Matrix Providers13

- Tenet Healthcare13

Top Industries Hiring
- Insurance
Physician Assistant Jobs in San Antonio: Frequently Asked Questions
How do I get a physician assistant job in San Antonio?
San Antonio's largest hiring blocks are its hospital systems clustered around the South Texas Medical Center, military-affiliated healthcare networks at JBSA, and the expanding urgent care and specialty clinic market in Stone Oak and Alamo Ranch. Candidates with surgical, emergency, or primary care rotations in high-volume trauma settings stand out locally. Bilingual Spanish proficiency is a meaningful differentiator given San Antonio's patient demographics.
Which companies hire physician assistants in San Antonio?
San Antonio physician assistant roles are posted by HealthTexas Medical, Optum, and Spine Clinic and others right now, based on current listings on Migrate Mate as of October 2026. The local market is anchored by large regional health systems, federally qualified health centers serving the city's underserved communities, and a growing network of multispecialty private practices expanding along the city's northern growth corridors.
Are there remote physician assistant jobs in San Antonio?
Yes, though remote opportunities are limited by nature given that most physician assistant roles require in-person patient care. About 0% of physician assistant openings tied to San Antonio are remote or hybrid as of October 2026, typically in telehealth triage, chronic disease management, or administrative clinical review roles rather than direct procedural or urgent care work.
How can I get a physician assistant job in San Antonio with little or no experience?
The most realistic entry path in San Antonio is through federally qualified health centers and community health programs, which regularly onboard new graduates due to high patient volume and workforce funding. Hospital system residency and postgraduate fellowship programs at local academic affiliates also offer structured onboarding. Candidates who completed clinical rotations at San Antonio-area facilities have a clear advantage, as local familiarity with patient population and care protocols matters to hiring teams.
Which industries hire the most physician assistants in San Antonio?
San Antonio physician assistant roles concentrate in Insurance, based on current listings on Migrate Mate as of October 2026. San Antonio's position as a major military city and its large uninsured and underinsured population drive sustained demand across hospital systems, defense health programs, and community health organizations throughout the metro.
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