Physician Assistant Jobs in San Antonio, TX

Physician Assistant jobs in San Antonio are concentrated in the South Texas Medical Center corridor, the Texas Medical Center affiliates along Fredericksburg Road, and growing suburban hubs in Stone Oak and the Loop 1604 corridor, across hospital systems, urgent care networks, and specialty clinics. Employers hiring right now include HealthTexas Medical, Optum, and Spine Clinic. Find a role that fits below and apply directly.

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Overview

Open roles214+
Top employerHealthTexas Medical
Work type100% On-site
Top credentialManaged care
Companies hiring14

Showing 5 of 214+ Physician Assistant jobs

Physician Assistant - Pulmonary & Sleep
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Added 1d ago
Physician Assistant - Pulmonary & Sleep
Pulmonary and Sleep Institute
San Antonio, Texas
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
$116k - $121k/yr
On-Site
Master's degree in nursing

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Nurse Practitioner / Physician Assistant - GYN Oncology
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Added 6d ago
Nurse Practitioner / Physician Assistant - GYN Oncology
University Health
San Antonio, Texas
Allied Health
Clinical Support
Healthcare Administration
$52.88 - $79.33/hr
10,000+

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Physician Assistant - Val Verde
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Added 6d ago
Physician Assistant - Val Verde
HealthTexas Medical Group
San Antonio, Texas
Allied Health
Clinical Support
Healthcare Administration
Managed care

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Physician Assistant - Leon Valley
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Added 6d ago
Physician Assistant - Leon Valley
HealthTexas Medical Group
San Antonio, Texas
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
Managed care

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Physician Assistant - Perrin Beitel
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Added 6d ago
Physician Assistant - Perrin Beitel
HealthTexas Medical Group
San Antonio, Texas
Allied Health
Clinical Support
Healthcare Administration
Managed care

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See All 214+ Physician Assistant Jobs in San Antonio

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Physician Assistant Job Market in San Antonio

Who's Hiring

  • HealthTexas Medical38
  • Optum25
  • Spine Clinic13
  • Matrix Providers13
  • Tenet Healthcare13

Top Industries Hiring

  • Insurance

Physician Assistant Jobs in San Antonio: Frequently Asked Questions

How do I get a physician assistant job in San Antonio?

San Antonio's largest hiring blocks are its hospital systems clustered around the South Texas Medical Center, military-affiliated healthcare networks at JBSA, and the expanding urgent care and specialty clinic market in Stone Oak and Alamo Ranch. Candidates with surgical, emergency, or primary care rotations in high-volume trauma settings stand out locally. Bilingual Spanish proficiency is a meaningful differentiator given San Antonio's patient demographics.

Which companies hire physician assistants in San Antonio?

San Antonio physician assistant roles are posted by HealthTexas Medical, Optum, and Spine Clinic and others right now, based on current listings on Migrate Mate as of October 2026. The local market is anchored by large regional health systems, federally qualified health centers serving the city's underserved communities, and a growing network of multispecialty private practices expanding along the city's northern growth corridors.

Are there remote physician assistant jobs in San Antonio?

Yes, though remote opportunities are limited by nature given that most physician assistant roles require in-person patient care. About 0% of physician assistant openings tied to San Antonio are remote or hybrid as of October 2026, typically in telehealth triage, chronic disease management, or administrative clinical review roles rather than direct procedural or urgent care work.

How can I get a physician assistant job in San Antonio with little or no experience?

The most realistic entry path in San Antonio is through federally qualified health centers and community health programs, which regularly onboard new graduates due to high patient volume and workforce funding. Hospital system residency and postgraduate fellowship programs at local academic affiliates also offer structured onboarding. Candidates who completed clinical rotations at San Antonio-area facilities have a clear advantage, as local familiarity with patient population and care protocols matters to hiring teams.

Which industries hire the most physician assistants in San Antonio?

San Antonio physician assistant roles concentrate in Insurance, based on current listings on Migrate Mate as of October 2026. San Antonio's position as a major military city and its large uninsured and underinsured population drive sustained demand across hospital systems, defense health programs, and community health organizations throughout the metro.

See All 214+ Physician Assistant Jobs in San Antonio

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