Principal Jobs in San Francisco, CA

Principal jobs in San Francisco are concentrated in SoMa, the Financial District, and the Mission District, with strong demand across K-12 education, technology, and professional services. Employers hiring right now include Genentech, Salesforce, and Amazon Web Services. See the openings below and apply to the ones that match your experience.

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Overview

Open roles776+
Top employerGenentech
Work type61% Hybrid
Top credentialBachelor's degree
Companies hiring43

Showing 5 of 776+ Principal jobs

Okta
Principal Machine Learning Engineer, SecureAI
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Okta
Added 1d ago
Principal Machine Learning Engineer, SecureAI
Okta
San Francisco, California
Cloud Engineering
DevOps
Solutions Engineering & Architecture
$238k - $326k/yr
Master's degree
5,001-10,000

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Adobe
Principal Architect — Adobe Stock
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Adobe
Added 1d ago
Principal Architect — Adobe Stock
Adobe
San Francisco, California
Cloud Architecture
Solutions Architecture
Solutions Engineering & Architecture
Technical Program Management
$190k - $361k/yr
Doctoral degree in Computer Science
10,000+

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City and County of San Francisco
Principal Project Analyst
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City and County of San Francisco
Added 1d ago
Principal Project Analyst
City and County of San Francisco
San Francisco, California
Project & Program Management
Business Analysis
$178k/yr
Hybrid
Bachelor's

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DoorDash
Principal Machine Learning Engineer, TEAM
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DoorDash
Added 1d ago
Principal Machine Learning Engineer, TEAM
DoorDash
San Francisco, California
Cloud & DevOps
Cloud Engineering
DevOps
Solutions Engineering & Architecture
$282k - $415k/yr
Military encouraged
10,000+

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Merck
Principal Scientist (Director), Clinical Research, Immunology
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Merck
Added 2d ago
Principal Scientist (Director), Clinical Research, Immunology
Merck
San Francisco, California
Business Strategy
Executive Leadership & C-Suite
Product Management
$256k - $403k/yr
10,000+

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See All 776+ Principal Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

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Principal Job Market in San Francisco

Who's Hiring

  • Genentech
    Genentech71
  • Salesforce
    Salesforce51
  • Amazon Web Services
    Amazon Web Services51
  • City and County of San Francisco
    City and County of San Francisco51
  • Intuit
    Intuit41

Top Industries Hiring

  • Technology & Software20
  • Government & Public Sector20
  • Science & Research10
  • Banking & Financial Services10
  • Biotechnology & Pharmaceuticals10

Principal Jobs in San Francisco: Frequently Asked Questions

How do I get a principal job in San Francisco?

Candidates with direct leadership experience in San Francisco's dominant sectors, including K-12 public schools run by SFUSD, private and charter networks in the Tenderloin and Bayview, and tech-sector principal engineering roles in SoMa and the Financial District, move fastest through hiring. Demonstrating familiarity with San Francisco's community demographics, multilingual student populations, or agile product environments gives applicants a clear edge over generalist candidates.

Which companies hire principals in San Francisco?

Companies currently hiring principals in San Francisco include Genentech, Salesforce, and Amazon Web Services, per current listings on Migrate Mate as of September 2026. San Francisco's market includes a distinct mix of SFUSD school sites, independent and charter schools in underserved neighborhoods, and technology firms seeking principal engineers or principal product managers in SoMa and Mission Bay.

Are there remote principal jobs in San Francisco?

Yes, though availability depends heavily on the type of principal role. About 87% of principal openings tied to San Francisco are remote or hybrid as of September 2026, with technology-sector roles such as principal engineer and principal product manager far more likely to offer flexible arrangements than school-based leadership positions, which remain almost entirely on-site.

How can I get a principal job in San Francisco with little or no experience?

The most realistic entry path in San Francisco for aspiring school principals is through SFUSD's teacher leadership pipelines, including instructional coach and assistant principal roles that build the administrative record hiring committees look for. For tech-sector principal roles, contributing as a senior engineer or senior product manager at a SoMa or Mission Bay firm first, and taking ownership of cross-functional initiatives, is the most direct route to an internal promotion.

Which industries hire the most principals in San Francisco?

The sectors hiring the most principals in San Francisco are Technology & Software, Government & Public Sector, and Science & Research, based on current listings on Migrate Mate as of September 2026. San Francisco's concentration of both a large urban public school district and a dense technology sector means demand for principals comes from two structurally different employer bases operating within a compact geographic area.

See All 776+ Principal Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

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