Mid Level PRN Nurse Jobs

Mid level prn nurse jobs go to clinicians ready to take ownership of complex patient assignments, guide newer staff through difficult cases, and exercise clinical judgment with minimal supervision. Roles are predominantly on-site across Healthcare & Medical Services, Insurance, and Biotechnology & Pharmaceuticals, with employers like Optum, Cone Health, and Deaconess Health System hiring at this level now.

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Overview

Open roles20
Top stateNorth Carolina
Top employerOptum
Top cityGreensboro, NC
Work type67% On-site
Top industryHealthcare

Showing 5 of 20+ Mid Level PRN Nurse jobs

Hospice Nurse Practitioner-PRN
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Added 1d ago
Hospice Nurse Practitioner-PRN
Optum
Franklin, Louisiana
Customer Service
Healthcare Administration
Patient Services & Wellbeing
$43 - $65/hr
CPR Certification
10,000+

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RN Congregational Nurse Bilingual PRN
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Added 1w ago
RN Congregational Nurse Bilingual PRN
Cone Health
Greensboro, North Carolina
Health Informatics
Healthcare Administration
Public Health
Hybrid
Bachelor of Science
10,000+

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IL Sup House Registered Nurse - PRN Nights
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Added 1w ago
IL Sup House Registered Nurse - PRN Nights
Deaconess Health System
Anna, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
$33 - $50/hr
Managed Registered Nurses (RNs)
5,001-10,000

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IL Sup House Registered Nurse - PRN Days
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Added 1w ago
IL Sup House Registered Nurse - PRN Days
Deaconess Health System
Anna, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
$33 - $50/hr
Managed Registered Nurses (RNs)
5,001-10,000

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Nurse Practitioner - Walk-In Physician Clinics - Days - PRN
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Added 1w ago
Nurse Practitioner - Walk-In Physician Clinics - Days - PRN
Memorial Hospital at Gulfport
Gulfport, Mississippi
Business Development
Growth Marketing
Marketing
Master's degree in nursing
1,001-5,000

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Mid Level PRN Nurse Job Market

Who's Hiring

Optum2 open roles
Cone Health2 open roles
Deaconess Health System2 open roles

Top Industries Hiring

  • Healthcare & Medical Services17
  • Insurance2
  • Biotechnology & Pharmaceuticals1
  • Consulting & Professional Services1

Mid Level PRN Nurse Jobs: Frequently Asked Questions

How do I get a mid level prn nurse job?

Position your application around clinical ownership, not just task completion. Highlight cases where you managed a full patient load independently, adapted to unexpected changes, or supported a colleague through a complex situation. Certifications relevant to your specialty, a consistent record of float or per diem shifts, and familiarity with multiple units or care settings all signal mid level readiness to hiring managers.

Which companies hire mid level prn nurses?

Companies hiring mid level prn nurses right now include Optum, Cone Health, and Deaconess Health System, based on current listings on Migrate Mate as of November 2026. Hospitals, regional health systems, outpatient surgery centers, and staffing agencies that fill flex and per diem positions tend to hire most actively at this level.

Are there remote mid level prn nurse jobs?

Yes, though most prn nursing roles remain on-site given direct patient care requirements. About 33% of mid level prn nurse openings are remote or hybrid as of November 2026, and these tend to be in utilization review, case management, or telehealth triage rather than bedside roles. Filtering by work setting on Migrate Mate helps narrow to those openings quickly.

How do I move up to a mid level prn nurse role?

Moving from entry level to mid level as a prn nurse means building a clinical record that shows independent judgment, not just task completion. Focus on deepening competency in a specialty, volunteering for float assignments to gain cross-unit exposure, and taking on charge or relief charge responsibilities when opportunities arise. Earning a specialty certification demonstrates that your skills meet a recognized standard and strengthens your case for mid level per diem positions.

Which industries hire the most mid level prn nurses?

Mid Level prn nurse roles concentrate in Healthcare & Medical Services, Insurance, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of November 2026. These sectors rely heavily on flexible staffing models to manage census fluctuations and specialty coverage gaps, which is precisely where experienced per diem nurses provide the most immediate value.