Product Operations Manager Jobs in San Diego, CA
Product Operations Manager jobs in San Diego, California are open across the metro, with employers like Amazon, CHANEL, and Intuit hiring at every experience level. Find a role that fits below and apply directly.
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The Manager, PLM Operation s, is a high-impact role that balances strategic leadership, operational execution, and people development . This position develops key partnerships across Engineering, Quality, Regulatory, Supply Chain, and Commercial departments to enable excellence throughout the product lifecycle. Success in this role looks like a motivated team with clear ownership and predictable delive ry, resulting in high PLM-stakeholder satisfaction . T he ideal candidate has strong negotiating and influencing skills, the ability to handle multiple tasks in parallel, and communicate effectively across all levels of the organization.
Responsibilities:
Lead team of Change Analysts supporting New Product Introduction and Sustaining Operations at multiple sites. Align business demand with team capacity .
Set clear performance expectations and champion employee development.
Acts as subject matter expert (SME) of PLM process requirements; define and apply best practices.
Lead global alignment discussions on strategy a nd requirements .
Trend, analyze, and report on change management data in order to improve product and process; develop recommendations based on data analysis .
Lead initiatives to reduce aging change s , improve throughput, and eliminate recurring process pain points.
Requirements:
Bachelor’s Degree in an engineering or scientific discipline
Typically requires 8 + years of relevant experience in engineering or similar with hands ‑ on understanding of PLM systems (e.g., Teamcenter or similar) and product lifecycle processes.
Strongly preferred: 1-3 years of management experience
Consistent track record of collaboration, including the ability to work with cross-functional teams across complex ecosystems with an enterprise mindset
Proven people ‑ management skills, including coaching, performance management, and conflict resolution.
A bility to navigate and influence across all levels of an organization, translating strategic vision into tangible outcomes
Experience applying quality regulation standards (e.g. 21CFR820, ISO 13485, ISO 14971, IVDD)
Strong understanding of manufacturing methods & terminology.
Knowledge of Lean Tools and Root Cause Analysis methodologies.
Proficient in process mapping with demonstrated track- record of driving solutions through continuous improvement culture and project management.
Occasional travel, night and/or weekend work may be required to support 24-hour global manufacturing operation.
We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.
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Find JobsProduct Operations Manager Job Market in San Diego
Who's Hiring
- Amazon4

- CHANEL2

- Intuit2

- Resmed2

- Illumina2

Top Industries Hiring
- Technology & Software13
- Retail6
- Healthcare & Medical Services4
- Biotechnology & Pharmaceuticals4
- E-Commerce & Online Marketplaces4
Product Operations Manager Jobs in San Diego: Frequently Asked Questions
How many product operations manager jobs are there in San Diego?
There are 74+ product operations manager openings in San Diego, California on Migrate Mate as of June 2026. New positions post regularly as San Diego employers hire.
Which companies hire product operations managers in San Diego?
San Diego product operations manager roles are posted by Amazon, CHANEL, and Intuit and others right now, based on current listings on Migrate Mate as of June 2026.
Are there remote product operations manager jobs in San Diego?
Yes. About 21% of product operations manager openings tied to San Diego are remote or hybrid as of June 2026. The rest are on-site roles based in and around San Diego.
Which industries hire the most product operations managers in San Diego?
Most product operations manager openings in San Diego sit in Technology & Software, Retail, and Healthcare & Medical Services, per current listings on Migrate Mate as of June 2026.
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