Program Director Jobs in Indianapolis, IN
Program Director jobs in Indianapolis are concentrated across healthcare systems, nonprofit and social services, and higher education, with active hiring in Midtown, the Near Northside, and downtown's corporate corridor. Employers hiring right now include State of Indiana, Sevita, and Eli Lilly. Find a role that fits below and apply directly.
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- Lead evidence-based practice (EBP) initiatives by designing, implementing, and evaluating clinical programs focused on hypertension and medication management, ensuring sustainable adoption across the organization.
- Partner with clinical, operational, and national leaders to drive strategic alignment, facilitate implementation, and support decision-making that advances quality patient care.
- Oversee program performance and continuous improvement by leveraging data analytics, measuring outcomes, tracking progress, and implementing corrective actions to achieve long-term success.
- Manage program operations and resources by directing project lifecycles, coordinating cross-functional teams, overseeing budgets, and ensuring successful execution of strategic initiatives.
- None Required.
-
High School diploma equivalency with 5 years of applicable cumulative job specific experience
required, with 2 of those years being in leadership/management OR Associate's degree/Bachelor's
degree with 3 years of applicable cumulative job specific experience required, with 2 of those years
being in leadership/management.
- Background in Pharmacy or Nursing highly preferred
- Proven track record in leading large-scale clinical implementations
- Exceptional relationship-building skills to navigate national and local stakeholder landscapes
- Mastery of project management tools and budgetary oversight
Life at Ascension: Where purpose meets opportunity:
Equal employment opportunity employer
Ascension provides Equal Employment Opportunities (EEO) to all associates and applicants for employment without regard to race, color, religion, sex/gender, sexual orientation, gender identity or expression, pregnancy, childbirth, and related medical conditions, lactation, breastfeeding, national origin, citizenship, age, disability, genetic information, veteran status, marital status, all as defined by applicable law, and any other legally protected status or characteristic in accordance with applicable federal, state and local laws. For further information, view the EEO Know Your Rights (English) poster or EEO Know Your Rights (Spanish) poster.
Fraud prevention notice
Prospective applicants should be vigilant against fraudulent job offers and interview requests. Scammers may use sophisticated tactics to impersonate Ascension employees. To ensure your safety, please remember: Ascension will never ask for payment or to provide banking or financial information as part of the job application or hiring process. Our legitimate email communications will always come from an @ascension.org email address; do not trust other domains, and an official offer will only be extended to candidates who have completed a job application through our authorized applicant tracking system.
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Benefits:
Various health insurance options & wellness plans
Retirement benefits including employer match plans
Long-term & short-term disability
Employee assistance programs (EAP)
Parental leave & adoption assistance
Tuition reimbursement
Ways to give back to your community
Benefit options and eligibility vary by position. Compensation varies based on factors including, but not limited to, experience, skills, education, performance, location and salary range at the time of the offer.
See All 31 Program Director Jobs in Indianapolis
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Find Program Director JobsProgram Director Job Market in Indianapolis
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
- Education
Program Director Jobs in Indianapolis: Frequently Asked Questions
How do I get a program director job in Indianapolis?
Your strongest path into a program director role in Indianapolis runs through the city's large healthcare networks, its dense nonprofit sector along the Near Northside, and the university and foundation community downtown. Candidates who can show direct experience managing budgets, leading cross-functional teams, and reporting to boards or funders stand out. Familiarity with Indianapolis's community development landscape is a genuine edge for mission-driven roles.
Which companies hire program directors in Indianapolis?
Employers hiring program directors in Indianapolis right now include State of Indiana, Sevita, and Eli Lilly, based on current listings on Migrate Mate as of July 2026. Indianapolis draws a broad mix of employer types, from large hospital systems and health insurers to national nonprofits with regional headquarters and state-funded human services agencies.
Are there remote program director jobs in Indianapolis?
Yes, though availability depends on the sector: program directors in healthcare operations and direct services are typically on-site, while those in grant management, policy, or foundation roles often have more flexibility. About 17% of program director openings tied to Indianapolis are remote or hybrid as of July 2026, reflecting broader hybrid norms across professional and administrative functions. Foundation and government-funded program roles tend to offer the most remote days locally.
How can I get a program director job in Indianapolis with little or no experience?
The most realistic entry path in Indianapolis is moving up from a program coordinator or program manager role within one of the city's large nonprofits, health systems, or community development organizations. Employers like community health centers, United Way affiliates, and city-funded workforce programs regularly hire coordinators who advance internally. Building relationships through Indianapolis-area professional networks and volunteering with local foundations can accelerate that progression significantly.
Which industries hire the most program directors in Indianapolis?
Most program director openings in Indianapolis sit in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Education, per current listings on Migrate Mate as of July 2026. Indianapolis's role as Indiana's healthcare hub, combined with its concentration of national nonprofit headquarters and state agency offices downtown, makes those sectors consistently the largest sources of local demand.
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